WO2006096709A3 - Process for preparing amorphous salts - Google Patents

Process for preparing amorphous salts Download PDF

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Publication number
WO2006096709A3
WO2006096709A3 PCT/US2006/008064 US2006008064W WO2006096709A3 WO 2006096709 A3 WO2006096709 A3 WO 2006096709A3 US 2006008064 W US2006008064 W US 2006008064W WO 2006096709 A3 WO2006096709 A3 WO 2006096709A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparing amorphous
magnesium
amorphous salts
esomeprazole
omeprazole
Prior art date
Application number
PCT/US2006/008064
Other languages
French (fr)
Other versions
WO2006096709B1 (en
WO2006096709A2 (en
Inventor
Vijayabhaskar Bolugoddu
Jaydeepkumar Dahayabha Lilakar
Purandhar Koilkonda
Ramchandra Reddy Pingili
Amarnath Reddy Lekkala
Venkata Rambabu Kammili
Swarupa Reddy Dudipala
Sharat Pandurang Narasapur
Srinivasa Rao Malina
Ramulu Akula
Original Assignee
Reddys Lab Ltd Dr
Reddys Lab Inc Dr
Vijayabhaskar Bolugoddu
Jaydeepkumar Dahayabha Lilakar
Purandhar Koilkonda
Ramchandra Reddy Pingili
Amarnath Reddy Lekkala
Venkata Rambabu Kammili
Swarupa Reddy Dudipala
Sharat Pandurang Narasapur
Srinivasa Rao Malina
Ramulu Akula
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reddys Lab Ltd Dr, Reddys Lab Inc Dr, Vijayabhaskar Bolugoddu, Jaydeepkumar Dahayabha Lilakar, Purandhar Koilkonda, Ramchandra Reddy Pingili, Amarnath Reddy Lekkala, Venkata Rambabu Kammili, Swarupa Reddy Dudipala, Sharat Pandurang Narasapur, Srinivasa Rao Malina, Ramulu Akula filed Critical Reddys Lab Ltd Dr
Priority to EP06737257A priority Critical patent/EP1856101A4/en
Priority to CA002600456A priority patent/CA2600456A1/en
Publication of WO2006096709A2 publication Critical patent/WO2006096709A2/en
Publication of WO2006096709A3 publication Critical patent/WO2006096709A3/en
Publication of WO2006096709B1 publication Critical patent/WO2006096709B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)

Abstract

Amorphous solid omeprazole magnesium or esomeprazole magnesium is prepared by subjecting a solution of omeprazole magnesium or esomeprazole magnesium to flash evaporation, such as by using an agitated thin film drier-vertical.
PCT/US2006/008064 2005-03-08 2006-03-07 Process for preparing amorphous salts WO2006096709A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP06737257A EP1856101A4 (en) 2005-03-08 2006-03-07 Process for preparing amorphous salts
CA002600456A CA2600456A1 (en) 2005-03-08 2006-03-07 Process for preparing amorphous salts

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IN227CH2005 2005-03-08
IN227/CHE/2005 2005-03-08
US67314205P 2005-04-20 2005-04-20
US60/673,142 2005-04-20
IN1543CH2005 2005-10-25
IN1543/CHE/2005 2005-10-25

Publications (3)

Publication Number Publication Date
WO2006096709A2 WO2006096709A2 (en) 2006-09-14
WO2006096709A3 true WO2006096709A3 (en) 2006-12-21
WO2006096709B1 WO2006096709B1 (en) 2007-01-18

Family

ID=36953969

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/008064 WO2006096709A2 (en) 2005-03-08 2006-03-07 Process for preparing amorphous salts

Country Status (3)

Country Link
EP (1) EP1856101A4 (en)
CA (1) CA2600456A1 (en)
WO (1) WO2006096709A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7553857B2 (en) * 2005-12-23 2009-06-30 Lek Pharmaceuticals D.D. S-omeprazole magnesium
EP2842953A1 (en) 2007-02-21 2015-03-04 Cipla Limited Process for the preparation of esomeprazole magnesium dihydrate
EP2147918A1 (en) 2008-07-21 2010-01-27 LEK Pharmaceuticals D.D. Process for the preparation of S-omeprazole magnesium in a stable form
FR2959509B1 (en) 2010-05-03 2012-07-13 Prod Chim Auxiliaires Et De Synthese PRECURSOR PHASE AND USE THEREOF FOR PREPARING MAGNESIUM TETRAHYDRATE SALT OF AN OMEPRAZOLE ENANTIOMER

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6713495B1 (en) * 1999-11-16 2004-03-30 Bernard Charles Sherman Magnesium omeprazole

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5248601A (en) * 2000-05-15 2001-11-26 Ranbaxy Laboratories Limited Novel amorphous form of omeprazole salts
US6894066B2 (en) * 2002-05-09 2005-05-17 Bernard Charles Sherman Magnesium salt of S-omeprazole
EP1556043A1 (en) * 2002-10-22 2005-07-27 Ranbaxy Laboratories, Ltd. Amorphous form of esomeprazole salts

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6713495B1 (en) * 1999-11-16 2004-03-30 Bernard Charles Sherman Magnesium omeprazole

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1856101A4 *

Also Published As

Publication number Publication date
WO2006096709B1 (en) 2007-01-18
EP1856101A4 (en) 2009-10-21
EP1856101A2 (en) 2007-11-21
WO2006096709A2 (en) 2006-09-14
CA2600456A1 (en) 2006-09-14

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