WO2009084023A3 - Amorphous ramelteon and process for the preparation thereof - Google Patents
Amorphous ramelteon and process for the preparation thereof Download PDFInfo
- Publication number
- WO2009084023A3 WO2009084023A3 PCT/IN2008/000679 IN2008000679W WO2009084023A3 WO 2009084023 A3 WO2009084023 A3 WO 2009084023A3 IN 2008000679 W IN2008000679 W IN 2008000679W WO 2009084023 A3 WO2009084023 A3 WO 2009084023A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ramelteon
- amorphous
- preparation
- dissolving
- solution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
Abstract
The present invention provides ramelteon substantially in an amorphous form and a process for its preparation, by preparing solution of ramelteon by dissolving in one or more solvents capable of dissolving the ramelteon; and substantially removing the solvent from the solution to provide amorphous ramelteon
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2081/MUM/2007 | 2007-10-19 | ||
IN2081MU2007 | 2007-10-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009084023A2 WO2009084023A2 (en) | 2009-07-09 |
WO2009084023A3 true WO2009084023A3 (en) | 2011-09-22 |
Family
ID=40824838
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2008/000679 WO2009084023A2 (en) | 2007-10-19 | 2008-10-16 | Amorphous ramelteon and process for the preparation thereof |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009084023A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2098519A1 (en) | 2007-05-31 | 2009-09-09 | Teva Pharmaceutical Industries Ltd. | Process for the synthesis of ramelteon and its intermediates |
EP2453891A1 (en) * | 2009-07-16 | 2012-05-23 | Vanda Pharmaceuticals Inc. | Use of a melatonin agonist for the treatment of sleep disorders including primary insomnia |
KR102307012B1 (en) | 2012-01-26 | 2021-09-30 | 반다 파마슈티칼즈, 인코퍼레이티드. | Treatment of circadian rhythm disorders |
US11918557B2 (en) | 2012-01-26 | 2024-03-05 | Vanda Pharmaceuticals Inc. | Treatment of circadian rhythm disorders |
JP6144358B2 (en) | 2012-12-18 | 2017-06-07 | ヴァンダ ファーマシューティカルズ インコーポレイテッド | Treatment of circadian rhythm disorders |
US10376487B2 (en) | 2013-11-12 | 2019-08-13 | Vanda Pharmaceuticals Inc. | Method of treatment |
US11090285B2 (en) | 2013-11-12 | 2021-08-17 | Vanda Pharmaceuticals Inc | Treatment of circadian rhythm disorders |
JP7407364B2 (en) * | 2019-02-12 | 2024-01-04 | 日本ジェネリック株式会社 | Ramelteon-containing solid preparation |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2612090A1 (en) * | 2005-06-22 | 2006-12-28 | Takeda Pharmaceutical Company Limited | Tablet containing hardly soluble active ingredient |
WO2007020337A1 (en) * | 2005-08-19 | 2007-02-22 | Sanofi-Aventis | Combination of a long-acting hypnotic agent and a short-acting hypnotic agent and therapeutic use of same |
-
2008
- 2008-10-16 WO PCT/IN2008/000679 patent/WO2009084023A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2612090A1 (en) * | 2005-06-22 | 2006-12-28 | Takeda Pharmaceutical Company Limited | Tablet containing hardly soluble active ingredient |
WO2007020337A1 (en) * | 2005-08-19 | 2007-02-22 | Sanofi-Aventis | Combination of a long-acting hypnotic agent and a short-acting hypnotic agent and therapeutic use of same |
Also Published As
Publication number | Publication date |
---|---|
WO2009084023A2 (en) | 2009-07-09 |
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