DE602005001553T2 - Verfahren zur herstellung einer 4-nitroimidazolverbindung - Google Patents

Verfahren zur herstellung einer 4-nitroimidazolverbindung Download PDF

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Publication number
DE602005001553T2
DE602005001553T2 DE602005001553T DE602005001553T DE602005001553T2 DE 602005001553 T2 DE602005001553 T2 DE 602005001553T2 DE 602005001553 T DE602005001553 T DE 602005001553T DE 602005001553 T DE602005001553 T DE 602005001553T DE 602005001553 T2 DE602005001553 T2 DE 602005001553T2
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DE
Germany
Prior art keywords
group
substituted
eine
einer
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005001553T
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German (de)
English (en)
Other versions
DE602005001553D1 (de
Inventor
Koichi Tokushima-shi SHINHAMA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of DE602005001553D1 publication Critical patent/DE602005001553D1/de
Application granted granted Critical
Publication of DE602005001553T2 publication Critical patent/DE602005001553T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dentistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
DE602005001553T 2004-02-18 2005-02-15 Verfahren zur herstellung einer 4-nitroimidazolverbindung Expired - Lifetime DE602005001553T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2004041381 2004-02-18
JP2004041381 2004-02-18
JP2004278999 2004-09-27
JP2004278999 2004-09-27
PCT/JP2005/002668 WO2005077913A1 (en) 2004-02-18 2005-02-15 Method for producing 4-nitroimidazole compound

Publications (2)

Publication Number Publication Date
DE602005001553D1 DE602005001553D1 (de) 2007-08-16
DE602005001553T2 true DE602005001553T2 (de) 2008-03-13

Family

ID=34863488

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005001553T Expired - Lifetime DE602005001553T2 (de) 2004-02-18 2005-02-15 Verfahren zur herstellung einer 4-nitroimidazolverbindung

Country Status (19)

Country Link
US (1) US7569702B2 (enExample)
EP (1) EP1720838B1 (enExample)
JP (1) JP4789483B2 (enExample)
KR (1) KR100830386B1 (enExample)
CN (1) CN100526300C (enExample)
AR (1) AR047672A1 (enExample)
AT (1) ATE366241T1 (enExample)
AU (1) AU2005212093B2 (enExample)
BR (1) BRPI0507777A (enExample)
CA (1) CA2555372A1 (enExample)
DE (1) DE602005001553T2 (enExample)
EG (1) EG24393A (enExample)
ES (1) ES2289695T3 (enExample)
MY (1) MY141776A (enExample)
RU (1) RU2345071C2 (enExample)
TW (1) TWI300409B (enExample)
UA (1) UA82773C2 (enExample)
WO (1) WO2005077913A1 (enExample)
ZA (1) ZA200606332B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI331607B (en) * 2002-10-15 2010-10-11 Otsuka Pharma Co Ltd 1-substituted-4-nitroimidazole compound
TW200624422A (en) * 2004-09-27 2006-07-16 Otsuka Pharma Co Ltd Process for production of 2-chloro-4-nitroimidazole
JP5072675B2 (ja) * 2007-04-03 2012-11-14 四国化成工業株式会社 ２−ハロイミダゾール化合物の製造方法
WO2010021409A1 (en) 2008-08-21 2010-02-25 Dynamit Nobel Gmbh Explosivstoff - Und Systemtechnik Methods for the production of 2-halo-4-nitroimidazole and intermediates thereof
RU2542988C2 (ru) * 2009-07-31 2015-02-27 Глоубал Элаенс Фор Тб Драг Дивелопмент Нитроимидазооксазины и их применения при противотуберкулезной терапии
CN103265494A (zh) * 2013-05-28 2013-08-28 南京理工大学 一种硝基咪唑含能化合物及其制备方法
CN105439957B (zh) * 2015-11-24 2018-05-08 浙江省诸暨合力化学对外贸易有限公司 一种合成2-溴-4-硝基咪唑的方法
KR20200116118A (ko) 2018-01-29 2020-10-08 오츠카 세이야쿠 가부시키가이샤 2-클로로-4-니트로이미다졸 유도체의 제조 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341548A (en) * 1964-04-29 1967-09-12 Hoffmann La Roche Nitroimidazoles and their preparation
DE2414280C2 (de) * 1974-03-25 1981-12-17 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 1-Methyl-5-nitroimidazolen
IL88943A (en) * 1988-01-15 1994-05-30 Rhone Poulenc Sante Process for preparing 1-alkyl-5- nitroimidazoles
RU2049780C1 (ru) * 1992-12-04 1995-12-10 Государственный научно-исследовательский институт "Кристалл" Способ получения производных 2-r-4(5)-нитроимидазолов
US5668127A (en) 1995-06-26 1997-09-16 Pathogenesis Corporation Nitroimidazole antibacterial compounds and methods of use thereof
TWI347946B (en) 2002-10-11 2011-09-01 Otsuka Pharma Co Ltd 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound
TWI331607B (en) * 2002-10-15 2010-10-11 Otsuka Pharma Co Ltd 1-substituted-4-nitroimidazole compound

Also Published As

Publication number Publication date
RU2345071C2 (ru) 2009-01-27
EG24393A (en) 2009-04-19
ATE366241T1 (de) 2007-07-15
AU2005212093A1 (en) 2005-08-25
BRPI0507777A (pt) 2007-07-17
MY141776A (en) 2010-06-30
AR047672A1 (es) 2006-02-01
WO2005077913A1 (en) 2005-08-25
AU2005212093B2 (en) 2008-04-03
RU2006133312A (ru) 2008-03-27
ES2289695T3 (es) 2008-02-01
EP1720838A1 (en) 2006-11-15
HK1097846A1 (zh) 2007-07-06
CA2555372A1 (en) 2005-08-25
CN1922154A (zh) 2007-02-28
JP2006117628A (ja) 2006-05-11
TWI300409B (en) 2008-09-01
DE602005001553D1 (de) 2007-08-16
EP1720838B1 (en) 2007-07-04
JP4789483B2 (ja) 2011-10-12
KR20060116857A (ko) 2006-11-15
US7569702B2 (en) 2009-08-04
US20070161802A1 (en) 2007-07-12
CN100526300C (zh) 2009-08-12
TW200530194A (en) 2005-09-16
UA82773C2 (uk) 2008-05-12
KR100830386B1 (ko) 2008-05-19
ZA200606332B (en) 2008-01-30

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