KR100830386B1 - 4-니트로이미다졸 화합물의 제조 방법 - Google Patents

4-니트로이미다졸 화합물의 제조 방법 Download PDF

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Publication number
KR100830386B1
KR100830386B1 KR1020067017553A KR20067017553A KR100830386B1 KR 100830386 B1 KR100830386 B1 KR 100830386B1 KR 1020067017553 A KR1020067017553 A KR 1020067017553A KR 20067017553 A KR20067017553 A KR 20067017553A KR 100830386 B1 KR100830386 B1 KR 100830386B1
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KR
South Korea
Prior art keywords
group
substituted
halogen
unsubstituted
phenyl
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Expired - Fee Related
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KR1020067017553A
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English (en)
Korean (ko)
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KR20060116857A (ko
Inventor
고이치 신하마
Original Assignee
오쓰까 세이야꾸 가부시키가이샤
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dentistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
KR1020067017553A 2004-02-18 2005-02-15 4-니트로이미다졸 화합물의 제조 방법 Expired - Fee Related KR100830386B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JPJP-P-2004-00041381 2004-02-18
JP2004041381 2004-02-18
JPJP-P-2004-00278999 2004-09-27
JP2004278999 2004-09-27

Publications (2)

Publication Number Publication Date
KR20060116857A KR20060116857A (ko) 2006-11-15
KR100830386B1 true KR100830386B1 (ko) 2008-05-19

Family

ID=34863488

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067017553A Expired - Fee Related KR100830386B1 (ko) 2004-02-18 2005-02-15 4-니트로이미다졸 화합물의 제조 방법

Country Status (19)

Country Link
US (1) US7569702B2 (enExample)
EP (1) EP1720838B1 (enExample)
JP (1) JP4789483B2 (enExample)
KR (1) KR100830386B1 (enExample)
CN (1) CN100526300C (enExample)
AR (1) AR047672A1 (enExample)
AT (1) ATE366241T1 (enExample)
AU (1) AU2005212093B2 (enExample)
BR (1) BRPI0507777A (enExample)
CA (1) CA2555372A1 (enExample)
DE (1) DE602005001553T2 (enExample)
EG (1) EG24393A (enExample)
ES (1) ES2289695T3 (enExample)
MY (1) MY141776A (enExample)
RU (1) RU2345071C2 (enExample)
TW (1) TWI300409B (enExample)
UA (1) UA82773C2 (enExample)
WO (1) WO2005077913A1 (enExample)
ZA (1) ZA200606332B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI331607B (en) * 2002-10-15 2010-10-11 Otsuka Pharma Co Ltd 1-substituted-4-nitroimidazole compound
TW200624422A (en) * 2004-09-27 2006-07-16 Otsuka Pharma Co Ltd Process for production of 2-chloro-4-nitroimidazole
JP5072675B2 (ja) * 2007-04-03 2012-11-14 四国化成工業株式会社 ２−ハロイミダゾール化合物の製造方法
WO2010021409A1 (en) 2008-08-21 2010-02-25 Dynamit Nobel Gmbh Explosivstoff - Und Systemtechnik Methods for the production of 2-halo-4-nitroimidazole and intermediates thereof
RU2542988C2 (ru) * 2009-07-31 2015-02-27 Глоубал Элаенс Фор Тб Драг Дивелопмент Нитроимидазооксазины и их применения при противотуберкулезной терапии
CN103265494A (zh) * 2013-05-28 2013-08-28 南京理工大学 一种硝基咪唑含能化合物及其制备方法
CN105439957B (zh) * 2015-11-24 2018-05-08 浙江省诸暨合力化学对外贸易有限公司 一种合成2-溴-4-硝基咪唑的方法
KR20200116118A (ko) 2018-01-29 2020-10-08 오츠카 세이야쿠 가부시키가이샤 2-클로로-4-니트로이미다졸 유도체의 제조 방법

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341548A (en) * 1964-04-29 1967-09-12 Hoffmann La Roche Nitroimidazoles and their preparation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2414280C2 (de) * 1974-03-25 1981-12-17 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 1-Methyl-5-nitroimidazolen
IL88943A (en) * 1988-01-15 1994-05-30 Rhone Poulenc Sante Process for preparing 1-alkyl-5- nitroimidazoles
RU2049780C1 (ru) * 1992-12-04 1995-12-10 Государственный научно-исследовательский институт "Кристалл" Способ получения производных 2-r-4(5)-нитроимидазолов
US5668127A (en) 1995-06-26 1997-09-16 Pathogenesis Corporation Nitroimidazole antibacterial compounds and methods of use thereof
TWI347946B (en) 2002-10-11 2011-09-01 Otsuka Pharma Co Ltd 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound
TWI331607B (en) * 2002-10-15 2010-10-11 Otsuka Pharma Co Ltd 1-substituted-4-nitroimidazole compound

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341548A (en) * 1964-04-29 1967-09-12 Hoffmann La Roche Nitroimidazoles and their preparation

Also Published As

Publication number Publication date
RU2345071C2 (ru) 2009-01-27
EG24393A (en) 2009-04-19
DE602005001553T2 (de) 2008-03-13
ATE366241T1 (de) 2007-07-15
AU2005212093A1 (en) 2005-08-25
BRPI0507777A (pt) 2007-07-17
MY141776A (en) 2010-06-30
AR047672A1 (es) 2006-02-01
WO2005077913A1 (en) 2005-08-25
AU2005212093B2 (en) 2008-04-03
RU2006133312A (ru) 2008-03-27
ES2289695T3 (es) 2008-02-01
EP1720838A1 (en) 2006-11-15
HK1097846A1 (zh) 2007-07-06
CA2555372A1 (en) 2005-08-25
CN1922154A (zh) 2007-02-28
JP2006117628A (ja) 2006-05-11
TWI300409B (en) 2008-09-01
DE602005001553D1 (de) 2007-08-16
EP1720838B1 (en) 2007-07-04
JP4789483B2 (ja) 2011-10-12
KR20060116857A (ko) 2006-11-15
US7569702B2 (en) 2009-08-04
US20070161802A1 (en) 2007-07-12
CN100526300C (zh) 2009-08-12
TW200530194A (en) 2005-09-16
UA82773C2 (uk) 2008-05-12
ZA200606332B (en) 2008-01-30

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