DE602004029493D1 - 5-(benz- (z) -yliden) -thiazolidin-4-onderivate als das immunsystem unterdrückende mittel - Google Patents

5-(benz- (z) -yliden) -thiazolidin-4-onderivate als das immunsystem unterdrückende mittel

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Publication number
DE602004029493D1
DE602004029493D1 DE602004029493T DE602004029493T DE602004029493D1 DE 602004029493 D1 DE602004029493 D1 DE 602004029493D1 DE 602004029493 T DE602004029493 T DE 602004029493T DE 602004029493 T DE602004029493 T DE 602004029493T DE 602004029493 D1 DE602004029493 D1 DE 602004029493D1
Authority
DE
Germany
Prior art keywords
onderivate
thiazolidin
benz
ylidene
immune system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004029493T
Other languages
English (en)
Inventor
Martin Bolli
Michael Scherz
Claus Mueller
Boris Mathys
Christoph Binkert
Oliver Nayler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Actelion Pharmaceuticals Ltd
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of DE602004029493D1 publication Critical patent/DE602004029493D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54Nitrogen and either oxygen or sulfur atoms
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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DE602004029493T 2003-11-21 2004-11-16 5-(benz- (z) -yliden) -thiazolidin-4-onderivate als das immunsystem unterdrückende mittel Active DE602004029493D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP0313072 2003-11-21
PCT/EP2004/012953 WO2005054215A1 (en) 2003-11-21 2004-11-16 5-(benz- (z) -ylidene) -thiazolidin-4-one derivatives as immunosuppressant agents

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DE602004029493D1 true DE602004029493D1 (de) 2010-11-18

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US (8) USRE43728E1 (de)
EP (2) EP1689726B1 (de)
JP (2) JP4061332B2 (de)
KR (1) KR100783835B1 (de)
CN (1) CN100567275C (de)
AR (1) AR047128A1 (de)
AT (1) ATE483698T1 (de)
AU (1) AU2004295047B2 (de)
BR (1) BRPI0416752B8 (de)
CA (1) CA2545582C (de)
CY (1) CY1111087T1 (de)
DE (1) DE602004029493D1 (de)
DK (1) DK1689726T3 (de)
ES (1) ES2352555T3 (de)
HR (1) HRP20100714T1 (de)
IL (1) IL175758A (de)
MY (1) MY145074A (de)
NO (1) NO336734B1 (de)
NZ (1) NZ547962A (de)
PL (1) PL1689726T3 (de)
PT (1) PT1689726E (de)
RU (1) RU2379299C2 (de)
SI (1) SI1689726T1 (de)
TW (1) TWI323659B (de)
WO (1) WO2005054215A1 (de)
ZA (1) ZA200605077B (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004295047B2 (en) 2003-11-21 2011-03-10 Actelion Pharmaceuticals Ltd 5-(benz- (Z) -ylidene) -thiazolidin-4-one derivatives as immunosuppressant agents
USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
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