DE602004023104D1 - Vereinfachte gewebeverarbeitung - Google Patents

Vereinfachte gewebeverarbeitung

Info

Publication number
DE602004023104D1
DE602004023104D1 DE602004023104T DE602004023104T DE602004023104D1 DE 602004023104 D1 DE602004023104 D1 DE 602004023104D1 DE 602004023104 T DE602004023104 T DE 602004023104T DE 602004023104 T DE602004023104 T DE 602004023104T DE 602004023104 D1 DE602004023104 D1 DE 602004023104D1
Authority
DE
Germany
Prior art keywords
tissue processing
processing
simplified
simplified tissue
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004023104T
Other languages
English (en)
Inventor
Azorides R Morales
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Miami
Original Assignee
University of Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Miami filed Critical University of Miami
Publication of DE602004023104D1 publication Critical patent/DE602004023104D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/16—Retorts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/44—Sample treatment involving radiation, e.g. heat
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B01L2300/1866—Microwaves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/305—Fixative compositions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
DE602004023104T 2003-10-24 2004-10-25 Vereinfachte gewebeverarbeitung Expired - Lifetime DE602004023104D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51356003P 2003-10-24 2003-10-24
PCT/US2004/035245 WO2005040763A1 (en) 2003-10-24 2004-10-25 Simplified tissue processing

Publications (1)

Publication Number Publication Date
DE602004023104D1 true DE602004023104D1 (de) 2009-10-22

Family

ID=34520114

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004023104T Expired - Lifetime DE602004023104D1 (de) 2003-10-24 2004-10-25 Vereinfachte gewebeverarbeitung

Country Status (11)

Country Link
US (2) US7470401B2 (de)
EP (1) EP1676117B1 (de)
JP (1) JP4527122B2 (de)
KR (1) KR20060115366A (de)
AT (1) ATE442576T1 (de)
AU (1) AU2004283291B2 (de)
CA (1) CA2543043C (de)
DE (1) DE602004023104D1 (de)
DK (1) DK1676117T3 (de)
ES (1) ES2331364T3 (de)
WO (1) WO2005040763A1 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2301924C (en) * 1997-08-20 2008-12-09 The University Of Miami A high quality, continuous throughput, tissue fixation-dehydration-fat removal-impregnation method
US7233340B2 (en) * 2003-02-27 2007-06-19 Applied Imaging Corp. Linking of images to enable simultaneous viewing of multiple objects
US7767152B2 (en) 2003-08-11 2010-08-03 Sakura Finetek U.S.A., Inc. Reagent container and slide reaction retaining tray, and method of operation
US9518899B2 (en) 2003-08-11 2016-12-13 Sakura Finetek U.S.A., Inc. Automated reagent dispensing system and method of operation
ES2535047T3 (es) * 2004-12-17 2015-05-04 Ventana Medical Systems, Inc. Método para la desparafinación de una muestra tisular a base de una microemulsión
FR2888971B1 (fr) * 2005-07-20 2007-11-02 Nicolas Bara Procede d'identification sequentielle d'echantillons
JP2007093254A (ja) * 2005-09-27 2007-04-12 Jokoh Co Ltd 迅速脱灰・脱脂・固定装置
JP5490414B2 (ja) * 2006-01-13 2014-05-14 ベンタナ・メデイカル・システムズ・インコーポレーテツド 生体サンプル処理用組成物及び方法
US9691043B2 (en) * 2006-04-11 2017-06-27 Leica Biosystems Melbourne Pty Ltd Device and method for cross-referencing
US8459509B2 (en) 2006-05-25 2013-06-11 Sakura Finetek U.S.A., Inc. Fluid dispensing apparatus
AT504371B8 (de) 2006-10-03 2008-09-15 Leica Mikrosysteme Gmbh Vorrichtung zur mikrowellen-gestützten präparation von proben
US20090298172A1 (en) * 2008-05-28 2009-12-03 Steven Paul Wheeler Histological specimen treatment apparatus and method
JP5758295B2 (ja) 2008-08-27 2015-08-05 ザ ユニバーシティー オブ マイアミ 病理グロシングツール、カセットおよびボード
JP5739351B2 (ja) 2009-03-11 2015-06-24 サクラ ファインテック ユー．エス．エー．， インコーポレイテッド 自動合焦方法および自動合焦装置
WO2010108930A2 (en) * 2009-03-23 2010-09-30 Engin Hasan Hueseyin Laboratory type quick film drying oven
DE102009025574A1 (de) * 2009-06-19 2010-12-23 Leica Biosystems Nussloch Gmbh Verfahren zum automatischen Bearbeiten von Gewebeproben in einem Gewebeprozessor
EP2278295A1 (de) * 2009-07-24 2011-01-26 Milestone S.r.l. Histologie-Gewebeprozessor für Gewebe eines einzelnen Hohlraums
US8831776B2 (en) * 2009-08-27 2014-09-09 Sakura Finetek U.S.A., Inc. Integrated tissue processing and embedding systems, and methods thereof
US10139613B2 (en) 2010-08-20 2018-11-27 Sakura Finetek U.S.A., Inc. Digital microscope and method of sensing an image of a tissue sample
US8752732B2 (en) 2011-02-01 2014-06-17 Sakura Finetek U.S.A., Inc. Fluid dispensing system
EP2518468B1 (de) * 2011-04-26 2019-07-24 Milestone S.r.l. Verfahren, Prozessor und Träger zur Verarbeitung von gefrorenen Gewebescheiben aus biologischen Proben
US8975562B2 (en) * 2011-05-03 2015-03-10 General Electric Company Over the range microwave safety door
US8932543B2 (en) 2011-09-21 2015-01-13 Sakura Finetek U.S.A., Inc. Automated staining system and reaction chamber
US8580568B2 (en) 2011-09-21 2013-11-12 Sakura Finetek U.S.A., Inc. Traceability for automated staining system
BR112014007683B1 (pt) * 2011-09-29 2021-02-09 The University Of Miami sistema e método para o processamento de uma amostra de um tecido sólido, módulo de extrapolação de tecido sólido e ferramenta de extrapolação
US10092905B2 (en) 2012-06-22 2018-10-09 Leica Biosystems Nussloch Gmbh Tissue sample container and methods
WO2013192606A1 (en) 2012-06-22 2013-12-27 Leica Biosystems Nussloch Gmbh Biopsy tissue sample transport device and method of using thereof
US9759711B2 (en) * 2013-02-05 2017-09-12 Genia Technologies, Inc. Nanopore arrays
US9389154B2 (en) 2013-03-15 2016-07-12 Leica Biosystems Nussloch Gmbh Tissue cassette with biasing element
US9052256B2 (en) 2013-03-15 2015-06-09 Leica Biosystems Nussloch Gmbh Method for processing and embedding tissue
CA2845830C (en) 2013-03-15 2020-10-27 Leica Biosystems Nussloch Gmbh Tissue cassette with retractable member
DE102013103971A1 (de) 2013-04-19 2014-11-06 Sensovation Ag Verfahren zum Erzeugen eines aus mehreren Teilbildern zusammengesetzten Gesamtbilds eines Objekts
US9733162B2 (en) 2014-02-11 2017-08-15 Ihor Turkevych Universal system, method and solution for the acceleration of the process of fixing, dehydrating and clearing the structure of biological tissue
WO2015154000A1 (en) 2014-04-04 2015-10-08 Massachusetts Institute Of Technology Active transport of charged molecules into, within, and/or from charged matrices
US10591392B2 (en) 2014-07-03 2020-03-17 Applikate Technologies Llc Simultaneous dehydration and staining of tissue for deep imaging
US10579959B2 (en) 2014-09-10 2020-03-03 Cerner Innovation, Inc. Intelligent routing of radio-frequency identification data
US10365189B2 (en) 2015-05-07 2019-07-30 Steven Wheeler Histological specimen treatment
CN105300753B (zh) * 2015-09-10 2018-10-30 山东骏腾医疗科技有限公司 一种用于病理切片的快速组织处理试剂
CN105606437B (zh) * 2016-03-01 2018-06-19 青岛锴锦医疗器械有限公司 一种快速病理组织脱水机
CN106018040B (zh) * 2016-07-19 2019-07-26 杨静 病理组织脱水装置
US11280803B2 (en) 2016-11-22 2022-03-22 Sakura Finetek U.S.A., Inc. Slide management system
CN106855475A (zh) * 2017-03-18 2017-06-16 王瑞才 一种用于病理切片的快速组织处理试剂
WO2019129646A1 (en) * 2017-12-29 2019-07-04 F. Hoffmann-La Roche Ag Tissue sample preparation system
CN111989558A (zh) * 2018-03-16 2020-11-24 因为傲可值有限公司 用于自动处理组织学样品的样品处理系统和方法
EP3897987A1 (de) * 2018-12-20 2021-10-27 TECAN Trading AG Verfahren zur behandlung einer probe
JP7330065B2 (ja) * 2019-10-30 2023-08-21 サクラ精機株式会社 組織片処理装置
CN115803065A (zh) 2020-06-15 2023-03-14 莱卡生物系统努斯洛赫有限责任公司 组织处理器和处理组织样品的方法
US20240344943A1 (en) * 2023-04-14 2024-10-17 Leica Biosystems Richmond, Inc. Method of Accelerated Histological Tissue Processing

Family Cites Families (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2150757A (en) * 1937-06-22 1939-03-14 Agfa Ansco Corp Film drier
US2684925A (en) * 1949-03-16 1954-07-27 Technicon Chemical Company Inc Liquid for treating tissue in histologic processing
US3546334A (en) 1965-05-21 1970-12-08 Lerner Lab Inc Composition for fixing and protecting a smear of body cells and method of applying same
US3389052A (en) * 1965-11-02 1968-06-18 Ehrenreich Theodore Fixing and drying cytological smears
GB1321712A (en) * 1970-03-17 1973-06-27 Shandon Elliott Ltd Sequential processing apparatus for processing an article by immersion
US3961097A (en) * 1971-10-28 1976-06-01 Gravlee Jr Joseph F Method of preparing tissue for microscopic examination
GB1454510A (en) * 1973-05-22 1976-11-03 Tetronics Research Dev Co Ltd Laying blood traces
US3892197A (en) * 1974-04-22 1975-07-01 Thomas D Kinney Light microscopy processing apparatus
IT1062484B (it) 1975-08-08 1984-10-10 Gen Electric Combinazione di fluido colorante e incollante per vetrini da microscopio
US4099483A (en) * 1976-04-07 1978-07-11 Shandon Southern Products Limited Tissue processing apparatus
US4199558A (en) * 1976-04-07 1980-04-22 Shandon Southern Products Limited Tissue processing method
US4141312A (en) * 1977-05-16 1979-02-27 Fisher Scientific Company Apparatus for histological tissue processing
US4221823A (en) * 1978-04-21 1980-09-09 Phillips Petroleum Company Process for mounting palynological specimens
DE2906650A1 (de) * 1979-02-21 1980-08-28 Pfrimmer Pharma Verfahren zur herstellung von transplantatkonserven
US4670386A (en) * 1980-05-23 1987-06-02 Stephen Sugaar Cancer tests using tumor antigen generated lymphokines and compositions
US4578282A (en) * 1982-02-04 1986-03-25 Harrison James S Composition for diagnostic reagents
US4545831A (en) * 1982-09-13 1985-10-08 The Mount Sinai School Of Medicine Method for transferring a thin tissue section
US4681996A (en) * 1982-12-16 1987-07-21 Cem Corporation Analytical process in which materials to be analyzed are directly and indirectly heated and dried by microwave radiation
DE3319564A1 (de) * 1983-05-30 1984-12-06 Arthur Pfeiffer Vakuumtechnik Wetzlar Gmbh, 6334 Asslar Verfahren zur herstellung flexibler, dauerhaltbargemachter nicht konservierter und konservierter biologischer materialien
DE8509640U1 (de) * 1985-03-30 1985-05-30 AGW Analysen-Geräte GmbH, 7970 Leutkirch Küvette
US4839194A (en) * 1985-07-05 1989-06-13 Bone Diagnostic Center Methods of preparing tissue samples
US5023187A (en) * 1985-09-13 1991-06-11 Fisher Scientific Company Method and device for accelerated treatment of thin sample on surface
US4656047A (en) * 1986-03-06 1987-04-07 Kok Lanbrecht P Rapid method for cell block preparation
US4835354A (en) * 1987-03-30 1989-05-30 Cem Corporation Microwave heating apparatus for laboratory analyses
FR2616273B1 (fr) * 1987-06-05 1989-10-20 Thomson Csf Resonateur hyperfrequence en mode de chuchotement en galerie
US5782897A (en) * 1987-06-26 1998-07-21 Microwave Medical Systems, Inc. Microwave heating apparatus for rapid tissue fixation
US4857300A (en) * 1987-07-27 1989-08-15 Cytocorp, Inc. Cytological and histological fixative formulation and methods for using same
US4882128A (en) * 1987-07-31 1989-11-21 Parr Instrument Company Pressure and temperature reaction vessel, method, and apparatus
US4946669A (en) 1987-10-09 1990-08-07 Siegfried Barry A Histological fixatives
US4911915A (en) * 1987-10-13 1990-03-27 Richard-Allan Medical Industries Method of processing tissue specimens and dehydrant solvent for use therein
US5544650A (en) * 1988-04-08 1996-08-13 Neuromedical Systems, Inc. Automated specimen classification system and method
US4891239A (en) * 1988-07-05 1990-01-02 Raytheon Company Method and apparatus for ultrafast microwave tissue fixation
EP0437480B1 (de) * 1988-10-10 1994-10-19 Commonwealth Scientific And Industrial Research Organisation Verfahren und vorrichtung für kontinuierliche chemische reaktionen
US5104640A (en) * 1989-03-17 1992-04-14 Wescor, Inc. Fixative composition for fixing blood smears to slides
EP0476004B1 (de) * 1989-06-07 1993-05-26 MOSHAMMER, Wolfgang, Dipl.-Ing. Verfahren und vorrichtung zur einstrahlung von mikrowellenenergie in wasserhaltige oder mit wasser versetzte materie
US5089288A (en) * 1989-06-24 1992-02-18 Berger Hermann J Method for impregnating tissue samples in paraffin
US5230865A (en) * 1989-09-08 1993-07-27 Cem Corporation Ventable rupture diaphragm-protected container for heating contained materials by microwave radiation
US5049510A (en) * 1990-01-05 1991-09-17 Fisher Scientific Company Process for histological tissue specimen treatment that includes variable sensitivity level control
US5030929A (en) * 1990-01-09 1991-07-09 General Atomics Compact waveguide converter apparatus
US5068086A (en) * 1990-06-12 1991-11-26 Raytheon Company Method and apparatus for batch fixating tissue specimens
DE4018955A1 (de) * 1990-06-13 1991-12-19 Werner Lautenschlaeger Probenbehaelter zum aufschliessen bzw. analysieren von probenmaterial
US5244787A (en) * 1991-01-31 1993-09-14 Biogenex Laboratories Antigen retrieval in formalin-fixed tissues using microwave energy
DE4143541C2 (de) * 1991-02-19 1999-03-04 Mls Gmbh Vorrichtung zum Extrahieren von Proben mittels eines Lösungsmittels bei erhöhter Temperatur
US5256571A (en) * 1991-05-01 1993-10-26 Cytyc Corporation Cell preservative solution
WO1992019952A1 (en) * 1991-05-07 1992-11-12 Wescor, Inc. Improved staining method for histology and cytology specimens
US5849517A (en) 1991-05-08 1998-12-15 Streck Laboratories, Inc. Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same
US5460797A (en) * 1991-05-08 1995-10-24 Streck Laboratories, Inc. Method for fixing tissues and cells for analysis using oxazolidine compounds
US5696887A (en) * 1991-08-05 1997-12-09 Biotek Solutions, Incorporated Automated tissue assay using standardized chemicals and packages
US5289140A (en) * 1991-08-16 1994-02-22 Dako Japan Co., Ltd. Consistent diagnostic test method using microwaves
DE4136416C2 (de) * 1991-11-05 1994-01-13 Gossler Kg Oscar Vorrichtung zur Mikrowellen-Bestrahlung von Materialien
US5422277A (en) 1992-03-27 1995-06-06 Ortho Diagnostic Systems Inc. Cell fixative composition and method of staining cells without destroying the cell surface
DE4223116A1 (de) * 1992-04-30 1993-11-04 Mikrowellen Labor Systeme Vorrichtung zur verdampfungsbehandlung von vorzugsweise fluessigen stoffen, insbesondere reagenzstoffen, oder zum aufbereiten oder analysieren von probenmaterial
US5401625A (en) * 1993-06-24 1995-03-28 E. K. Industries, Inc. Histological composition for light microscopy
US5624706A (en) * 1993-07-15 1997-04-29 Electron R+D International, Inc. Method for fabricating electron multipliers
US5830417A (en) * 1993-09-24 1998-11-03 Duquesne University Of The Holy Ghost Method and apparatus for microwave assisted chemical reactions
US5725835A (en) * 1993-11-11 1998-03-10 Lautenschlaeger; Werner Device for initiating and/or promoting chemical or physical processes in a material
US5432056A (en) * 1993-11-15 1995-07-11 Ventana Medical Systems, Inc. Bisulfite-based tissue fixative
US5431952A (en) * 1994-02-28 1995-07-11 Board Of Trustees Operating Michigan State University Method for preservation of biological tissue
EP0751809B1 (de) * 1994-03-22 1998-11-11 LAUTENSCHLÄGER, Werner Vorrichtung zum aufbereiten und/oder extrahieren von proben mittels eines verdampfungsfähigen mittels bei erhöhter temperatur
CA2147593C (en) * 1994-04-22 2008-07-29 Hyman C. Birnboim Dual purpose tissue fixative
US5532462A (en) * 1994-04-29 1996-07-02 Communications & Power Industries Method of and apparatus for heating a reaction vessel with microwave energy
US5712605A (en) * 1994-05-05 1998-01-27 Hewlett-Packard Co. Microwave resonator
CA2153215A1 (en) * 1994-07-06 1996-01-07 Lu Wang Treatment of paraffin embedded tissue for gene analysis
WO1996021075A1 (de) * 1995-01-05 1996-07-11 Lautenschlaeger Werner Vorrichtung zur wärmebehandlung von materialien in einer heizkammer
DE19503591A1 (de) * 1995-02-03 1996-08-08 Werner Lautenschlaeger Verfahren und Vorrichtung zur Extraktions-Behandlung einer Probe
US5625706A (en) * 1995-05-31 1997-04-29 Neopath, Inc. Method and apparatus for continously monitoring and forecasting slide and specimen preparation for a biological specimen population
US5796080A (en) * 1995-10-03 1998-08-18 Cem Corporation Microwave apparatus for controlling power levels in individual multiple cells
US6072086A (en) * 1996-04-12 2000-06-06 Intergen Company Method and composition for controlling formaldehyde fixation by delayed quenching
EP0822403B1 (de) * 1996-08-02 1998-07-29 Milestone S.r.l. Verfahren zur Bearbeitung von organischen Proben
DE19639022B4 (de) * 1996-09-23 2013-03-21 Mwt Mikrowellen Labor Technik Ag Verfahren und Vorrichtung zum Herstellen hochreiner flüssiger Chemikalien
DE19639021A1 (de) * 1996-09-23 1998-03-26 Mikrowellen Systeme Mws Gmbh Vorrichtung und Verfahren zum Behandeln einer chemischen Substanz durch Erhitzen unter Druck
US5679333A (en) * 1996-10-25 1997-10-21 Dunphy; Brian William Formaldehyde-free tissue preservative compositions
DE19652339A1 (de) 1996-12-17 1998-06-18 Microm Laborgeraete Gmbh Vorrichtung zur Behandlung von Objekten
ATE240514T1 (de) * 1997-07-15 2003-05-15 Bernard Pajak Methode zum fixieren und einbetten von geweben für histologische präperate
CA2301924C (en) * 1997-08-20 2008-12-09 The University Of Miami A high quality, continuous throughput, tissue fixation-dehydration-fat removal-impregnation method
US6793890B2 (en) * 1997-08-20 2004-09-21 The University Of Miami Rapid tissue processor
US6017725A (en) * 1997-08-21 2000-01-25 Aaper Alcohol And Chemical Company Cytological fixative and dehydrating agent for treating histological and cytological tissue
US6183995B1 (en) * 1997-09-05 2001-02-06 Lifespan Biosciences, Inc. Methods of measuring gene expression using wax-embedded tissue specimens
US6033912A (en) 1997-11-13 2000-03-07 Milestone S.R.L. Method of controlling a chemical process heated by microwave radiation
DE69942309D1 (de) 1998-05-18 2010-06-10 Igenex Inc In situ hybridisierungsverfahren zur entdeckung von zielnukleinsäuren
DE69917779T2 (de) * 1998-06-30 2005-06-16 Lamina, Inc. Zytologische und histologische fixier-zusammensetzung und verfahren zur verwendung
US6054695A (en) * 1998-07-30 2000-04-25 Milestone S.R.L. Apparatus for condensing gases within a microwave radiation field
US6242723B1 (en) * 1998-07-30 2001-06-05 Milestone S.R.L. Apparatus for performing chemical and physical processes without sample transfer within a microwave radiation field
US6204375B1 (en) * 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
DE60026309T2 (de) * 1999-05-10 2006-12-14 California Institute Of Technology, Pasadena Verwendung eines räumlich-zeitlichen reaktionsverhaltens in sensor-arrays zur detektion von analyten in fluiden
DE19928820A1 (de) 1999-06-17 2000-12-21 Ulrich Groth Fixiermittel für Zellen und Gewebe von Lebewesen
US6291180B1 (en) * 1999-09-29 2001-09-18 American Registry Of Pathology Ultrasound-mediated high-speed biological reaction and tissue processing
WO2001044784A1 (en) 1999-12-14 2001-06-21 University Of Miami Microwave unit and system for tissue processing
US6248535B1 (en) * 1999-12-20 2001-06-19 University Of Southern California Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
US6337189B1 (en) * 2000-02-08 2002-01-08 Streck Laboratories, Inc. Fixative system, method and composition for biological testing
WO2001067820A1 (en) 2000-03-03 2001-09-13 Ted Pella, Inc. Apparatus for dampening standing wave pattern generation in microwave oven
DE10015794A1 (de) * 2000-03-27 2001-10-11 Univ Schiller Jena Vorrichtung zur Durchführung chemischer Reaktionen und Prozesse in Hochfrequenzfeldern
EP1156309B1 (de) * 2000-05-18 2003-04-16 Precisa Instruments AG Automatische Probenpräparation
DE10037417A1 (de) * 2000-07-24 2002-02-07 Friedrich Schiller Uni Jena Bu Vorrichtung zur Durchführung multipler chemischer Reaktionen und Prozesse in Hochfrequenzfeldern
DE10104320A1 (de) * 2001-01-25 2002-08-01 Univ Schiller Jena Vorrichtung zur Erfüllung von Sicherheitsfunktionen in Räumen mit Hochfrequenzstrahlung
US6875583B2 (en) * 2001-05-22 2005-04-05 Ted Pella, Inc. Rapid microwave-assisted fixation of fresh tissue
US20030194352A1 (en) * 2001-12-20 2003-10-16 Milestone S.R.L. Device for closing a plurality of digestion vessesls
DE20120649U1 (de) * 2001-12-20 2002-04-18 MLS Mikrowellen-Labor-Systeme GmbH, 88299 Leutkirch Vorrichtung zum Verschließen eines topfförmigen Aufschlussbehälters
US20030127313A1 (en) * 2001-12-20 2003-07-10 Milestone S.R.L. Device for closing a pot-like digestion vessel
US6797928B2 (en) * 2002-04-23 2004-09-28 Ted Pella, Inc. Method and apparatus for the rapid decalcification and fixation of mineralized tissues
US7138226B2 (en) * 2002-05-10 2006-11-21 The University Of Miami Preservation of RNA and morphology in cells and tissues
WO2004033622A2 (en) 2002-05-10 2004-04-22 The University Of Miami Preservation of rna and morphology in cells and tissues
ATE285070T1 (de) 2003-03-05 2005-01-15 Milestone Srl Fixierungslösung
EP1464388A1 (de) * 2003-04-04 2004-10-06 Mikrowellen-Systeme MWS GmbH Mikrowellen-Behandlung von chemischen Substanzen in einem Behälter
US7273720B1 (en) * 2004-12-02 2007-09-25 Collaborative Laboratory Services, Llc Rapid tissue processing method and apparatus

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US20050090017A1 (en) 2005-04-28
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US8288168B2 (en) 2012-10-16
WO2005040763A1 (en) 2005-05-06
DK1676117T3 (da) 2009-11-09
EP1676117B1 (de) 2009-09-09
ES2331364T3 (es) 2009-12-30
US7470401B2 (en) 2008-12-30
JP2007509354A (ja) 2007-04-12
ATE442576T1 (de) 2009-09-15
KR20060115366A (ko) 2006-11-08
JP4527122B2 (ja) 2010-08-18
CA2543043C (en) 2013-09-17
AU2004283291A1 (en) 2005-05-06
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