ES2535047T3 - Método para la desparafinación de una muestra tisular a base de una microemulsión - Google Patents

Método para la desparafinación de una muestra tisular a base de una microemulsión Download PDF

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Publication number
ES2535047T3
ES2535047T3 ES05824805.5T ES05824805T ES2535047T3 ES 2535047 T3 ES2535047 T3 ES 2535047T3 ES 05824805 T ES05824805 T ES 05824805T ES 2535047 T3 ES2535047 T3 ES 2535047T3
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Spain
Prior art keywords
microemulsion
dewaxing
paraffin
tissue sample
sample based
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ES05824805.5T
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English (en)
Inventor
Brian Kram
Christopher Bieniarz
Paul D. Drumheller
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Ventana Medical Systems Inc
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Ventana Medical Systems Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Extraction Or Liquid Replacement (AREA)

Abstract

Procedimiento de retirada del medio impregnado en parafina de una muestra biológica impregnada en parafina que comprende: poner en contacto la muestra biológica impregnada de parafina con una microemulsión desparafinante que comprende tensoactivo, solvente orgánico no polar y agua, en la que el tensoactivo es soluble tanto en agua como en el solvente orgánico no polar, transfiriendo la parafina a la microemulsión; y Separar la microemulsión.

Description

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Claims (1)

  1. imagen1
ES05824805.5T 2004-12-17 2005-11-18 Método para la desparafinación de una muestra tisular a base de una microemulsión Active ES2535047T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63694204P 2004-12-17 2004-12-17
US636942P 2004-12-17
PCT/US2005/041853 WO2006065442A2 (en) 2004-12-17 2005-11-18 Methods and compositions for a microemulsion-based tissue treatment

Publications (1)

Publication Number Publication Date
ES2535047T3 true ES2535047T3 (es) 2015-05-04

Family

ID=36084210

Family Applications (1)

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ES05824805.5T Active ES2535047T3 (es) 2004-12-17 2005-11-18 Método para la desparafinación de una muestra tisular a base de una microemulsión

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US (4) US20060134732A1 (es)
EP (5) EP2390648A1 (es)
JP (4) JP5137585B2 (es)
AU (1) AU2005316930B2 (es)
CA (5) CA2764289C (es)
DK (2) DK2392908T3 (es)
ES (1) ES2535047T3 (es)
WO (1) WO2006065442A2 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2424988T3 (es) 2002-04-15 2013-10-10 Ventana Medical Systems, Inc. Sistema automatizado de coloración de placas portaobjetos con elevada velocidad de producción
US11249095B2 (en) 2002-04-15 2022-02-15 Ventana Medical Systems, Inc. Automated high volume slide processing system
US7468161B2 (en) * 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
EP2390648A1 (en) * 2004-12-17 2011-11-30 Ventana Medical Systems, Inc. Methods and compositions for a microemulsion-based tissue treatment
WO2006116199A2 (en) 2005-04-21 2006-11-02 Celerus Diagnostics, Inc. Parallel processing fluidic method and apparatus for automated rapid immunohistochemistry
WO2007084429A2 (en) * 2006-01-13 2007-07-26 Ventana Medical Systems, Inc. Biological sample processing composition and method
US20100075372A1 (en) * 2006-09-28 2010-03-25 Taka-Aki Sato Method for deparaffinization of paraffin-embedded specimen and method for analysis of paraffin-embedded specimen
CN102209889B (zh) 2008-11-12 2015-05-13 文塔纳医疗系统公司 用于加热载持标本的载玻片的方法及设备
EP2468862A1 (en) * 2010-12-23 2012-06-27 Qiagen GmbH Method and kit for processing wax-embedded biological samples
CN103930761B (zh) * 2011-02-28 2017-06-13 丹麦达科有限公司 用于预处理包埋的生物样本的不混溶两相系统
DE102011002197B4 (de) * 2011-04-20 2019-03-07 Leica Biosystems Nussloch Gmbh Verfahren und Vorrichtung zum Ablösen und/oder Vereinzeln einer histologischen Probe
WO2013079072A1 (en) * 2011-11-30 2013-06-06 Dako Denmark A/S Method and system for automated deparaffinization and non-immunohistochemical special staining of tissue samples
US8753836B2 (en) * 2012-01-23 2014-06-17 Richard-Allan Scientific Company Dewaxing buffer containing a water-soluble organic solvent and methods of use thereof
EP2873028A4 (en) * 2012-06-28 2016-05-25 Pelican Imaging Corp SYSTEMS AND METHOD FOR DETECTING DEFECTIVE CAMERA ARRAYS, OPTICAL ARRAYS AND SENSORS
JP6253657B2 (ja) 2012-10-08 2017-12-27 ヴェンタナ メディカル システムズ, インク. 有色素サンプルを明確化するための方法、キット、及びシステム
US9080167B2 (en) * 2012-11-16 2015-07-14 Covaris, Inc. System and method for processing paraffin embedded samples
WO2014079802A2 (en) 2012-11-20 2014-05-30 Ventana Medical Systems, Inc. Laser ablation inductively-coupled plasma mass spectral tissue diagnostics
AU2014363717B2 (en) 2013-12-13 2016-12-22 Ventana Medical Systems, Inc. Automated histological processing of biological specimens and associated technology
WO2017158469A1 (en) 2016-03-15 2017-09-21 Sabic Global Technologies B.V. Methods of making alpha, beta-unsaturated carboxylic acids or salts
CN106770226A (zh) * 2016-11-29 2017-05-31 河南中医药大学 一种用于观察植物花药发育结构变化的染色方法
US10852219B2 (en) 2017-11-02 2020-12-01 Diagnostic Biosystems Deparaffinizing compositions and methods
EP4211445A1 (en) 2020-09-08 2023-07-19 Clarapath, Inc. Automated tissue section transfer system with high throughput
JP7309140B1 (ja) 2022-04-07 2023-07-18 学校法人昭和大学 顕微鏡標本作製用平板及び顕微鏡標本の作製方法
DE102022111890B3 (de) 2022-05-12 2023-03-16 Dermagnostix GmbH Verfahren zur Deparaffinierung von Formalin-fixiertem Paraffin-eingebettetem Gewebe

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2681298A (en) * 1951-01-27 1954-06-15 Technicon Chemical Company Inc Preparation for and method of treating histological tissue
US3546334A (en) * 1965-05-21 1970-12-08 Lerner Lab Inc Composition for fixing and protecting a smear of body cells and method of applying same
US3624197A (en) * 1969-09-04 1971-11-30 Philip Schain Water-soluble tissue infiltrating and embedding compositions
US3761401A (en) * 1971-04-26 1973-09-25 Marathon Oil Co Hydrocarbon extraction process using micellar systems
CA1041382A (en) * 1974-11-08 1978-10-31 Vincent N.R. Sewell Method of enhancing oleophilic and hydrophobic properties of absorbent material
DE2826363C2 (de) * 1978-06-16 1984-08-16 Merck Patent Gmbh, 6100 Darmstadt Deckfolie zur Verwendung in mikroskopischen Färbeverfahren und Verfahren zu ihrer Herstellung
US4402708A (en) * 1980-11-18 1983-09-06 Exxon Research & Engineering Co. Dialkyl amine derivatives of phthalic acid
JPS57111399A (en) * 1980-11-19 1982-07-10 Du Pont Emulsion for aqueous detergent
US4446044A (en) * 1981-04-09 1984-05-01 E. I. Du Pont De Nemours And Company Aqueous water-in-oil cleaning emulsion
US4404181A (en) * 1981-10-15 1983-09-13 Cambridge Chemical Products, Inc. Extended-life tissue fixative composition and method of using the same
US4526586A (en) * 1982-09-24 1985-07-02 The United States Of America As Represented By The Secretary Of Agriculture Microemulsions from vegetable oil and aqueous alcohol with 1-butanol surfactant as alternative fuel for diesel engines
US4557734A (en) * 1984-08-08 1985-12-10 The United States Of America As Represented By The Secretary Of Agriculture Microemulsions from vegetable oil and lower alcohol with octanol surfactant as alternative fuel for diesel engines
US4946669A (en) * 1987-10-09 1990-08-07 Siegfried Barry A Histological fixatives
US5130238A (en) * 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
US5219560A (en) * 1989-03-20 1993-06-15 Kobayashi Kose Co., Ltd. Cosmetic composition
US5106730A (en) * 1989-07-24 1992-04-21 Microprobe Corporation Lactam-containing compositions and methods useful for the hybridization of nucleic acids
US5124444A (en) * 1989-07-24 1992-06-23 Microprobe Corporation Lactam-containing compositions and methods useful for the extraction of nucleic acids
JPH0376797A (ja) * 1989-08-21 1991-04-02 Lion Corp 液体洗浄剤組成物
US5521061A (en) * 1992-07-17 1996-05-28 Aprogenex, Inc. Enhancement of probe signal in nucleic acid-mediated in-situ hybridization studies
US5492837A (en) * 1993-08-27 1996-02-20 Biogenex Laboratories Mounting medium for microscope slide preparations
US5552087A (en) * 1993-11-15 1996-09-03 Ventana Medical Systems, Inc. High temperature evaporation inhibitor liquid
US6632598B1 (en) 1994-03-11 2003-10-14 Biogenex Laboratories Deparaffinization compositions and methods for their use
US6451551B1 (en) * 1994-03-11 2002-09-17 Biogenex Laboratories Releasing embedding media from tissue specimens
JPH0841263A (ja) * 1994-08-01 1996-02-13 Nisshin Kaken Kk 塩素化ポリプロピレンエマルションの製造方法
JP3522914B2 (ja) * 1994-08-09 2004-04-26 ヤスハラケミカル株式会社 病理組織検査用溶剤
WO1997016731A1 (en) * 1995-11-02 1997-05-09 Thomas Jefferson University Immunocytochemical staining of exfoliated cervical samples
JPH09157698A (ja) * 1995-12-05 1997-06-17 Olympus Optical Co Ltd 洗浄組成物及び洗浄方法
US5866748A (en) * 1996-04-23 1999-02-02 Exxon Research And Engineering Company Hydroisomerization of a predominantly N-paraffin feed to produce high purity solvent compositions
JP3742464B2 (ja) * 1996-08-09 2006-02-01 ヤスハラケミカル株式会社 プレパラート用封入剤
US5856289A (en) * 1996-12-02 1999-01-05 Kennedy; Michael Stephen Hard surface cleaner with d-limonene, ethylene slycolbutyl ether, nonylphenol ethoxylate, and phosphate
CA2235358A1 (en) * 1997-04-21 1998-10-21 Masahiro Takahashi Surface modifier composition
WO1999000470A1 (en) * 1997-06-30 1999-01-07 The Procter & Gamble Company LIGHT-DUTY LIQUID OR GEL DISHWASHING DETERGENT COMPOSITIONS HAVING CONTROLLED pH AND DESIRABLE FOOD SOIL REMOVAL, RHEOLOGICAL AND SUDSING CHARACTERISTICS
PT1000138E (pt) * 1997-07-31 2004-01-30 Du Pont Microemulsoes aquosas
DK1005633T3 (da) * 1997-08-20 2008-12-15 Univ Miami Vævsfikserings-dehydratiserings-fedtfjernelses-imprægneringsmetode med höj kvalitet og kontinuerligt gennemlöb
US6124253A (en) * 1997-09-16 2000-09-26 Church & Dwight Co., Inc. Aqueous composition for low-temperature metal-cleaning and method of use
US6649368B1 (en) * 1997-10-24 2003-11-18 Cell Marque Corporation Composition and method for treating tissue samples
NZ506722A (en) * 1998-02-24 2002-10-25 Weyerhaeuser Co Method for removing wax from a pulp furnish
EP1082611A4 (en) 1998-06-02 2003-01-15 Ventana Med Syst Inc METHODS OF COLORING BIOLOGICAL SAMPLES BY COMBINING REAGENTS INSTABLE ON THE OBJECT BLADE
US6143512A (en) * 1998-08-17 2000-11-07 Markovic; Nenad Cap-pap test
US7410753B2 (en) * 1998-09-03 2008-08-12 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
JP3782663B2 (ja) * 1998-09-03 2006-06-07 ベンタナ・メデイカル・システムズ・インコーポレーテツド 生物学的試料からの包埋媒体の除去および自動化された染色装置における細胞コンディショニング
US6255393B1 (en) * 1998-10-22 2001-07-03 Nippon Shokubai Co., Ltd. Aqueous polymer dispersion, production process therefor, and aqueous release agent
US6013683A (en) * 1998-12-17 2000-01-11 Dow Corning Corporation Single phase silicone and water compositions
US6544798B1 (en) * 1999-02-26 2003-04-08 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
JP2000258318A (ja) * 1999-03-09 2000-09-22 Muto Kagaku Kk 溶媒置換用組成物及びこれを用いた標本作成方法
US6916608B2 (en) * 1999-09-10 2005-07-12 Becton, Dickinson And Company Composition for providing long term stability to cells for diagnostic testing
JP2001125006A (ja) * 1999-10-27 2001-05-11 Muto Kagaku Kk 封入剤を印刷したカバーガラス及びその製造方法
US6337189B1 (en) * 2000-02-08 2002-01-08 Streck Laboratories, Inc. Fixative system, method and composition for biological testing
EP1325300A1 (en) * 2000-09-15 2003-07-09 Biogenex Laboratories ENHANCEMENT OF i IN SITU /i HYBRIDIZATION
DE60043845D1 (de) * 2000-10-02 2010-04-01 Mallinckrodt Baker B V Verwendung eines verbesserten Befestigungsmittels für Objektträger
FR2819201B1 (fr) * 2001-01-09 2003-02-21 Atofina Procede de nettoyage d'une surface solide par elimination de salissures organiques et/ou minerales au moyen d'une microemulsion
JP4801841B2 (ja) * 2001-02-19 2011-10-26 東レ東燃機能膜合同会社 熱可塑性樹脂微多孔膜の洗浄方法およびこれを利用した熱可塑性樹脂微多孔膜の製造方法
DE10144989B4 (de) * 2001-09-12 2007-11-08 Leica Microsystems Nussloch Gmbh System zum Färben und Eindecken von Objektträgern
US6891502B2 (en) * 2002-01-10 2005-05-10 Mems Optical, Inc. Variable shape antenna etching system and antenna formed thereby
US7468161B2 (en) * 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
ES2424988T3 (es) * 2002-04-15 2013-10-10 Ventana Medical Systems, Inc. Sistema automatizado de coloración de placas portaobjetos con elevada velocidad de producción
ATE435418T1 (de) * 2002-05-28 2009-07-15 Diapath S P A Zusammensetzung für die herstellung von histologischen, autopsischen und zytologischen proben
US20040122390A1 (en) * 2002-12-23 2004-06-24 Kimberly-Clark Worldwide, Inc. Low evaporative superabsorbent products and composites and methods for utilizing the same
US6953507B2 (en) * 2003-03-21 2005-10-11 Ecolab Inc. Low temperature cleaning
US7186522B2 (en) * 2003-03-31 2007-03-06 Cytyc Corporation Papanicolau staining process
KR20060115366A (ko) * 2003-10-24 2006-11-08 더 유니버시티 오브 마이애미 간소화시킨 조직 가공
KR100837041B1 (ko) 2004-02-18 2008-06-11 신에쓰 가가꾸 고교 가부시끼가이샤 대형 합성 석영 유리 기판의 제조 방법
EP2390648A1 (en) * 2004-12-17 2011-11-30 Ventana Medical Systems, Inc. Methods and compositions for a microemulsion-based tissue treatment
WO2007084429A2 (en) * 2006-01-13 2007-07-26 Ventana Medical Systems, Inc. Biological sample processing composition and method
FR2901124B1 (fr) * 2006-05-17 2008-06-27 Oreal Emulsion huile dans eau fine

Also Published As

Publication number Publication date
JP2008524584A (ja) 2008-07-10
CA2764289C (en) 2013-12-24
EP2390648A1 (en) 2011-11-30
EP2390647A1 (en) 2011-11-30
WO2006065442A3 (en) 2006-09-14
EP2392908B1 (en) 2019-08-21
EP2392909A1 (en) 2011-12-07
WO2006065442A2 (en) 2006-06-22
JP2014197009A (ja) 2014-10-16
US20060134732A1 (en) 2006-06-22
EP2392908A1 (en) 2011-12-07
CA2764621C (en) 2013-12-24
JP5137585B2 (ja) 2013-02-06
CA2588783C (en) 2012-03-27
US20080261266A1 (en) 2008-10-23
US8652803B2 (en) 2014-02-18
CA2764621A1 (en) 2006-06-22
CA2764289A1 (en) 2006-06-22
CA2764335A1 (en) 2006-06-22
EP1825246A2 (en) 2007-08-29
AU2005316930B2 (en) 2009-06-18
CA2588783A1 (en) 2006-06-22
EP2392909B1 (en) 2016-12-14
DK2392909T3 (en) 2017-02-13
DK2392908T3 (da) 2019-10-21
CA2764294A1 (en) 2006-06-22
US8512978B2 (en) 2013-08-20
JP2012215581A (ja) 2012-11-08
JP6018121B2 (ja) 2016-11-02
CA2764335C (en) 2015-04-14
US20130029376A1 (en) 2013-01-31
US8288121B2 (en) 2012-10-16
JP6018122B2 (ja) 2016-11-02
JP2014206538A (ja) 2014-10-30
CA2764294C (en) 2013-12-24
EP1825246B1 (en) 2015-04-01
AU2005316930A1 (en) 2006-06-22
US20130309718A1 (en) 2013-11-21

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