DE602004010787T2 - 3-substitutierte-2(arylalkyl)-1-azabicycloalkane und methoden zu deren verwendung - Google Patents

3-substitutierte-2(arylalkyl)-1-azabicycloalkane und methoden zu deren verwendung Download PDF

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Publication number
DE602004010787T2
DE602004010787T2 DE602004010787T DE602004010787T DE602004010787T2 DE 602004010787 T2 DE602004010787 T2 DE 602004010787T2 DE 602004010787 T DE602004010787 T DE 602004010787T DE 602004010787 T DE602004010787 T DE 602004010787T DE 602004010787 T2 DE602004010787 T2 DE 602004010787T2
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Prior art keywords
pyridinyl
azabicyclo
methyl
oct
carboxamide
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Expired - Lifetime
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DE602004010787T
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German (de)
English (en)
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DE602004010787D1 (de
Inventor
Anatoly A. Greensboro MAZUROV
Jozef Rural Hall KLUCIK
Lan Advance MIAO
Angela S. Jamestown SEAMANS
Teresa Youngpeter Greensboro PHILLIPS
Jeffrey Daniel Winston-Salem SCHMITT
Craig Harrison Winston-salem MILLER
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Gyre Therapeutics Inc
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Targacept Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

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DE602004010787T 2003-02-21 2004-02-20 3-substitutierte-2(arylalkyl)-1-azabicycloalkane und methoden zu deren verwendung Expired - Lifetime DE602004010787T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/372,642 US6953855B2 (en) 1998-12-11 2003-02-21 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
US372642 2003-02-21
PCT/US2004/005044 WO2004076449A2 (en) 2003-02-21 2004-02-20 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof

Publications (2)

Publication Number Publication Date
DE602004010787D1 DE602004010787D1 (de) 2008-01-31
DE602004010787T2 true DE602004010787T2 (de) 2008-12-24

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DE602004010787T Expired - Lifetime DE602004010787T2 (de) 2003-02-21 2004-02-20 3-substitutierte-2(arylalkyl)-1-azabicycloalkane und methoden zu deren verwendung

Country Status (22)

Country Link
US (11) US6953855B2 (https=)
EP (1) EP1594869B9 (https=)
JP (3) JP4828407B2 (https=)
KR (3) KR101098481B1 (https=)
CN (2) CN101220026A (https=)
AT (1) ATE381563T1 (https=)
AU (1) AU2004215386B2 (https=)
BR (1) BRPI0407708A (https=)
CA (1) CA2514135C (https=)
CY (1) CY1107175T1 (https=)
DE (1) DE602004010787T2 (https=)
DK (1) DK1594869T3 (https=)
EA (1) EA011033B1 (https=)
ES (1) ES2300749T3 (https=)
IL (3) IL169797A (https=)
MX (1) MXPA05008926A (https=)
NO (3) NO332757B1 (https=)
NZ (3) NZ565177A (https=)
PL (3) PL395718A1 (https=)
PT (1) PT1594869E (https=)
WO (1) WO2004076449A2 (https=)
ZA (1) ZA200506515B (https=)

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