DE60115900D1 - Nukleotidsequenzen kodierend für das mdha gen aus corynebakterium glutamicum - Google Patents

Nukleotidsequenzen kodierend für das mdha gen aus corynebakterium glutamicum

Info

Publication number
DE60115900D1
DE60115900D1 DE60115900T DE60115900T DE60115900D1 DE 60115900 D1 DE60115900 D1 DE 60115900D1 DE 60115900 T DE60115900 T DE 60115900T DE 60115900 T DE60115900 T DE 60115900T DE 60115900 D1 DE60115900 D1 DE 60115900D1
Authority
DE
Germany
Prior art keywords
polynucleotide
sequence
malate dehydrogenase
gene
thr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60115900T
Other languages
English (en)
Other versions
DE60115900T2 (de
Inventor
Douwe Molenaar
Der Rest Eduard Van
Andre Drysch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7647660&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60115900(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Degussa GmbH filed Critical Degussa GmbH
Priority to DE60115900T priority Critical patent/DE60115900T2/de
Application granted granted Critical
Publication of DE60115900D1 publication Critical patent/DE60115900D1/de
Publication of DE60115900T2 publication Critical patent/DE60115900T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE60115900T 2000-07-04 2001-06-20 Nukleotidsequenzen kodierend für das mdha gen aus corynebakterium glutamicum Expired - Lifetime DE60115900T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE60115900T DE60115900T2 (de) 2000-07-04 2001-06-20 Nukleotidsequenzen kodierend für das mdha gen aus corynebakterium glutamicum

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10032350A DE10032350A1 (de) 2000-07-04 2000-07-04 Neue für das mdhA-Gen kodierende Nukleotidsequenzen
DE10032350 2000-07-04
DE60115900T DE60115900T2 (de) 2000-07-04 2001-06-20 Nukleotidsequenzen kodierend für das mdha gen aus corynebakterium glutamicum
PCT/EP2001/006928 WO2002002778A1 (en) 2000-07-04 2001-06-20 Nucleotide sequences which code for the mdha gene from corynebacterium glutamicum

Publications (2)

Publication Number Publication Date
DE60115900D1 true DE60115900D1 (de) 2006-01-19
DE60115900T2 DE60115900T2 (de) 2006-08-03

Family

ID=7647660

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10032350A Withdrawn DE10032350A1 (de) 2000-07-04 2000-07-04 Neue für das mdhA-Gen kodierende Nukleotidsequenzen
DE60115900T Expired - Lifetime DE60115900T2 (de) 2000-07-04 2001-06-20 Nukleotidsequenzen kodierend für das mdha gen aus corynebakterium glutamicum

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE10032350A Withdrawn DE10032350A1 (de) 2000-07-04 2000-07-04 Neue für das mdhA-Gen kodierende Nukleotidsequenzen

Country Status (9)

Country Link
US (2) US6995002B2 (de)
EP (1) EP1297148B1 (de)
KR (1) KR100904744B1 (de)
CN (1) CN1440458A (de)
AT (1) ATE312929T1 (de)
AU (1) AU2001279674A1 (de)
DE (2) DE10032350A1 (de)
ES (1) ES2254459T3 (de)
WO (1) WO2002002778A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100506990C (zh) * 2004-02-24 2009-07-01 中国科学院植物研究所 小麦高光效和抗逆相关的苹果酸脱氢酶、其编码基因及培育抗逆植物的方法
KR100789270B1 (ko) 2005-11-30 2008-01-02 씨제이 주식회사 Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용하여 ｌ-라이신을 생산하는 방법
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
KR100822041B1 (ko) * 2006-12-21 2008-04-15 씨제이제일제당 (주) 몰리브덴 보조인자 생합성 효소 에이 코딩 유전자의 발현이강화된 코리네박테리움 속 미생물 및 이를 이용한엘-라이신 생산방법
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
KR101072708B1 (ko) * 2008-12-17 2011-10-11 씨제이제일제당 (주) ５＇－크산틸산 생산능이 향상된 미생물 및 이를 이용한 ５＇－크산틸산의 생산방법
DE102013204728A1 (de) * 2013-03-18 2014-09-18 Wacker Chemie Ag Mikroorganismenstamm und Verfahren zur fermentativen Herstellung von C4-Verbindungen aus C5-Zuckern
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
KR101947945B1 (ko) * 2018-01-25 2019-02-13 씨제이제일제당 (주) L-아미노산을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아미노산의 생산방법
EP3594355A1 (de) 2018-07-12 2020-01-15 Evonik Operations GmbH Verfahren zur fermentativen herstellung von l-lysin
CN109161555A (zh) * 2018-09-07 2019-01-08 大连大学 一种海洋低温苹果酸脱氢酶基因及其重组表达载体
KR102129379B1 (ko) * 2018-10-10 2020-07-02 한국과학기술원 고활성의 말산 탈수소효소가 도입된 숙신산 생성용 변이 미생물 및 이를 이용한 숙신산 제조방법
CN110129342B (zh) * 2019-05-17 2021-11-23 河南农业大学 玉米高赖氨酸基因ZmcytMdh4的分子标记及其应用
KR102258159B1 (ko) * 2021-01-29 2021-05-27 씨제이제일제당 (주) 신규한 말레이트 디하이드로게나제 변이체 및 이를 이용한 l-라이신 생산 방법
CN115449518B (zh) * 2021-06-08 2024-01-26 中国科学院天津工业生物技术研究所 基于mdh基因的具有启动子活性的多核苷酸及其用途
JP2023038944A (ja) * 2021-09-07 2023-03-17 花王株式会社 芳香族化合物の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK284235B6 (en) * 1997-10-04 2004-11-03 Forschungszentrum Juelich Gmbh Method for microbial production of amino acids of the aspartate and/or glutamate family and agents which can be used in the said method
CZ20014659A3 (cs) * 1999-06-25 2002-09-11 Basf Aktiengesellschaft Geny Corynebacterium glutamicum kódující proteiny účastnící se metabolismu uhlíku a produkce energie
WO2001000804A2 (en) * 1999-06-25 2001-01-04 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins
DE19929365A1 (de) 1999-06-25 2000-12-28 Basf Lynx Bioscience Ag Teilsequenzen der Gene des Primär- und Sekundärmetabolismus aus Corynebacterium glutamicum und ihr Einsatz zur mikrobiellen Herstellung von Primär- und Sekundärmetaboliten
JP2003144161A (ja) * 1999-07-02 2003-05-20 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP4623825B2 (ja) * 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド

Also Published As

Publication number Publication date
ATE312929T1 (de) 2005-12-15
DE60115900T2 (de) 2006-08-03
DE10032350A1 (de) 2002-01-24
WO2002002778A8 (en) 2002-02-07
EP1297148A1 (de) 2003-04-02
US6995002B2 (en) 2006-02-07
KR100904744B1 (ko) 2009-06-29
US7067288B2 (en) 2006-06-27
ES2254459T3 (es) 2006-06-16
KR20030013521A (ko) 2003-02-14
EP1297148B1 (de) 2005-12-14
US20020037568A1 (en) 2002-03-28
CN1440458A (zh) 2003-09-03
WO2002002778A1 (en) 2002-01-10
AU2001279674A1 (en) 2002-01-14
US20040142454A1 (en) 2004-07-22

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: DEGUSSA GMBH, 40474 DUESSELDORF, DE

8327 Change in the person/name/address of the patent owner

Owner name: EVONIK DEGUSSA GMBH, 40474 DUESSELDORF, DE

8365 Fully valid after opposition proceedings