DE60114572T2 - Ein verfahren zur herstellung von salzen des l-carnitins und alkanoyl l-carnitins mit galaktarsäure - Google Patents

Ein verfahren zur herstellung von salzen des l-carnitins und alkanoyl l-carnitins mit galaktarsäure Download PDF

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Publication number
DE60114572T2
DE60114572T2 DE60114572T DE60114572T DE60114572T2 DE 60114572 T2 DE60114572 T2 DE 60114572T2 DE 60114572 T DE60114572 T DE 60114572T DE 60114572 T DE60114572 T DE 60114572T DE 60114572 T2 DE60114572 T2 DE 60114572T2
Authority
DE
Germany
Prior art keywords
carnitine
alkanoyl
solution
chloride
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60114572T
Other languages
German (de)
English (en)
Other versions
DE60114572D1 (de
Inventor
Carlo A. Bagolini
Angelo Sigma-Tau Ind. Farmac. Ri. Sp DE LUCA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Application granted granted Critical
Publication of DE60114572D1 publication Critical patent/DE60114572D1/de
Publication of DE60114572T2 publication Critical patent/DE60114572T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/285—Polyhydroxy dicarboxylic acids having five or more carbon atoms, e.g. saccharic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60114572T 2000-02-10 2001-02-09 Ein verfahren zur herstellung von salzen des l-carnitins und alkanoyl l-carnitins mit galaktarsäure Expired - Lifetime DE60114572T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM200006 2000-02-10
IT2000RM000060A IT1316988B1 (it) 2000-02-10 2000-02-10 Procedimento migliorato di preparazione industriale di mucati dellal-carnitina e di alcanoil l-carnitine.
PCT/IT2001/000056 WO2001058850A1 (en) 2000-02-10 2001-02-09 A process for the preparation of salts of l-carnitine and alkanoyl l-carnitine with mucic acid

Publications (2)

Publication Number Publication Date
DE60114572D1 DE60114572D1 (de) 2005-12-08
DE60114572T2 true DE60114572T2 (de) 2006-07-27

Family

ID=11454414

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60114572T Expired - Lifetime DE60114572T2 (de) 2000-02-10 2001-02-09 Ein verfahren zur herstellung von salzen des l-carnitins und alkanoyl l-carnitins mit galaktarsäure

Country Status (19)

Country Link
US (1) US6693215B2 (enExample)
EP (1) EP1257524B1 (enExample)
JP (1) JP4708655B2 (enExample)
KR (1) KR100709629B1 (enExample)
CN (1) CN1169781C (enExample)
AT (1) ATE308509T1 (enExample)
AU (1) AU2001234079A1 (enExample)
CA (1) CA2399501C (enExample)
CZ (1) CZ303031B6 (enExample)
DE (1) DE60114572T2 (enExample)
DK (1) DK1257524T3 (enExample)
ES (1) ES2249411T3 (enExample)
HK (1) HK1052682B (enExample)
HU (1) HU226129B1 (enExample)
IT (1) IT1316988B1 (enExample)
MX (1) MXPA02007682A (enExample)
PL (1) PL201605B1 (enExample)
SK (1) SK287250B6 (enExample)
WO (1) WO2001058850A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118638020B (zh) * 2024-08-08 2024-11-19 杭州海尔希畜牧科技有限公司 L-天门冬氨酸l(-)肉碱(1:1)的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1172394B (it) * 1983-12-28 1987-06-18 Sigma Tau Ind Farmaceuti Sali della l-carnitina e di alcuni alcanoil derivati della l-carnitina e procedimento per la loro preparazione
AU718308B2 (en) 1996-05-31 2000-04-13 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Stable, non-hygroscopic salts of L(-)carnitine and alkanoyl L(-)carnitines, a process for their preparation and solid, orally administrable compositions containing such salts
IT1289974B1 (it) * 1997-02-25 1998-10-19 Aldo Fassi Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine

Also Published As

Publication number Publication date
CN1398251A (zh) 2003-02-19
EP1257524B1 (en) 2005-11-02
WO2001058850A1 (en) 2001-08-16
HU226129B1 (en) 2008-04-28
CZ303031B6 (cs) 2012-03-07
HUP0204378A3 (en) 2005-05-30
PL358098A1 (en) 2004-08-09
SK287250B6 (sk) 2010-04-07
IT1316988B1 (it) 2003-05-26
HUP0204378A2 (hu) 2003-04-28
PL201605B1 (pl) 2009-04-30
ES2249411T3 (es) 2006-04-01
KR100709629B1 (ko) 2007-04-19
AU2001234079A1 (en) 2001-08-20
HK1052682B (zh) 2005-05-06
CA2399501C (en) 2010-06-29
US20030130539A1 (en) 2003-07-10
ATE308509T1 (de) 2005-11-15
ITRM20000060A1 (it) 2001-08-10
SK11552002A3 (sk) 2002-12-03
US6693215B2 (en) 2004-02-17
DK1257524T3 (da) 2006-02-13
HK1052682A1 (en) 2003-09-26
EP1257524A1 (en) 2002-11-20
JP2003522749A (ja) 2003-07-29
KR20020073543A (ko) 2002-09-26
ITRM20000060A0 (it) 2000-02-10
CA2399501A1 (en) 2001-08-16
JP4708655B2 (ja) 2011-06-22
DE60114572D1 (de) 2005-12-08
CN1169781C (zh) 2004-10-06
MXPA02007682A (es) 2003-01-28
CZ20022533A3 (cs) 2003-02-12

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