HUP0204378A2 - Eljárás L-karnitin- és alkanoil-L-karnitin-sók mucinsav alkalmazásával megvalósított előállítására - Google Patents

Eljárás L-karnitin- és alkanoil-L-karnitin-sók mucinsav alkalmazásával megvalósított előállítására

Info

Publication number
HUP0204378A2
HUP0204378A2 HU0204378A HUP0204378A HUP0204378A2 HU P0204378 A2 HUP0204378 A2 HU P0204378A2 HU 0204378 A HU0204378 A HU 0204378A HU P0204378 A HUP0204378 A HU P0204378A HU P0204378 A2 HUP0204378 A2 HU P0204378A2
Authority
HU
Hungary
Prior art keywords
carnitine
alkanoyl
salts
preparation
mucic acid
Prior art date
Application number
HU0204378A
Other languages
English (en)
Inventor
Carlo Alberto Bagolini
Angelo Luca
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of HUP0204378A2 publication Critical patent/HUP0204378A2/hu
Publication of HUP0204378A3 publication Critical patent/HUP0204378A3/hu
Publication of HU226129B1 publication Critical patent/HU226129B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/285—Polyhydroxy dicarboxylic acids having five or more carbon atoms, e.g. saccharic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány tárgya javított eljárás L-karnitin- és alkanoil-L-karnitin-mucátok ipari méretű előállítására, amelyet szakaszosüzemben, normál kémiai reaktorban, keveréssel hajtanak végre, ésnagyobb hígítású, homogén fázist alkalmaznak. Ó
HU0204378A 2000-02-10 2001-02-09 A process for the preparation of salts of l-carnitine and alkanoyl l-carnitine with mucic acid HU226129B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000RM000060A IT1316988B1 (it) 2000-02-10 2000-02-10 Procedimento migliorato di preparazione industriale di mucati dellal-carnitina e di alcanoil l-carnitine.
PCT/IT2001/000056 WO2001058850A1 (en) 2000-02-10 2001-02-09 A process for the preparation of salts of l-carnitine and alkanoyl l-carnitine with mucic acid

Publications (3)

Publication Number Publication Date
HUP0204378A2 true HUP0204378A2 (hu) 2003-04-28
HUP0204378A3 HUP0204378A3 (en) 2005-05-30
HU226129B1 HU226129B1 (en) 2008-04-28

Family

ID=11454414

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0204378A HU226129B1 (en) 2000-02-10 2001-02-09 A process for the preparation of salts of l-carnitine and alkanoyl l-carnitine with mucic acid

Country Status (19)

Country Link
US (1) US6693215B2 (hu)
EP (1) EP1257524B1 (hu)
JP (1) JP4708655B2 (hu)
KR (1) KR100709629B1 (hu)
CN (1) CN1169781C (hu)
AT (1) ATE308509T1 (hu)
AU (1) AU2001234079A1 (hu)
CA (1) CA2399501C (hu)
CZ (1) CZ303031B6 (hu)
DE (1) DE60114572T2 (hu)
DK (1) DK1257524T3 (hu)
ES (1) ES2249411T3 (hu)
HK (1) HK1052682B (hu)
HU (1) HU226129B1 (hu)
IT (1) IT1316988B1 (hu)
MX (1) MXPA02007682A (hu)
PL (1) PL201605B1 (hu)
SK (1) SK287250B6 (hu)
WO (1) WO2001058850A1 (hu)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1172394B (it) * 1983-12-28 1987-06-18 Sigma Tau Ind Farmaceuti Sali della l-carnitina e di alcuni alcanoil derivati della l-carnitina e procedimento per la loro preparazione
IT1289974B1 (it) * 1997-02-25 1998-10-19 Aldo Fassi Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine
PL188558B1 (pl) * 1996-05-31 2005-02-28 Sigma Tau Ind Farmaceuti Sole L(-)karnityny i alkanoilo L(-)karnityn, sposób ich wytwarzania i kompozycje farmaceutyczne zawierające takie sole

Also Published As

Publication number Publication date
CN1398251A (zh) 2003-02-19
CZ303031B6 (cs) 2012-03-07
CZ20022533A3 (cs) 2003-02-12
DK1257524T3 (da) 2006-02-13
PL201605B1 (pl) 2009-04-30
PL358098A1 (en) 2004-08-09
CA2399501C (en) 2010-06-29
IT1316988B1 (it) 2003-05-26
CN1169781C (zh) 2004-10-06
ITRM20000060A1 (it) 2001-08-10
ITRM20000060A0 (it) 2000-02-10
WO2001058850A1 (en) 2001-08-16
HK1052682A1 (en) 2003-09-26
HU226129B1 (en) 2008-04-28
ES2249411T3 (es) 2006-04-01
MXPA02007682A (es) 2003-01-28
KR100709629B1 (ko) 2007-04-19
SK287250B6 (sk) 2010-04-07
ATE308509T1 (de) 2005-11-15
CA2399501A1 (en) 2001-08-16
SK11552002A3 (sk) 2002-12-03
DE60114572D1 (de) 2005-12-08
JP4708655B2 (ja) 2011-06-22
HK1052682B (zh) 2005-05-06
AU2001234079A1 (en) 2001-08-20
EP1257524A1 (en) 2002-11-20
JP2003522749A (ja) 2003-07-29
US6693215B2 (en) 2004-02-17
US20030130539A1 (en) 2003-07-10
DE60114572T2 (de) 2006-07-27
EP1257524B1 (en) 2005-11-02
HUP0204378A3 (en) 2005-05-30
KR20020073543A (ko) 2002-09-26

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Legal Events

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MM4A Lapse of definitive patent protection due to non-payment of fees