CN1169781C - L-肉碱和烷酰基l-肉碱与粘酸的盐的制备方法 - Google Patents

L-肉碱和烷酰基l-肉碱与粘酸的盐的制备方法 Download PDF

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Publication number
CN1169781C
CN1169781C CNB018047637A CN01804763A CN1169781C CN 1169781 C CN1169781 C CN 1169781C CN B018047637 A CNB018047637 A CN B018047637A CN 01804763 A CN01804763 A CN 01804763A CN 1169781 C CN1169781 C CN 1169781C
Authority
CN
China
Prior art keywords
carnitine
alkanoyl
solution
inner salt
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB018047637A
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English (en)
Chinese (zh)
Other versions
CN1398251A (zh
Inventor
Ca
C·A·巴格里尼
A·德鲁卡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of CN1398251A publication Critical patent/CN1398251A/zh
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Publication of CN1169781C publication Critical patent/CN1169781C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/285—Polyhydroxy dicarboxylic acids having five or more carbon atoms, e.g. saccharic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB018047637A 2000-02-10 2001-02-09 L-肉碱和烷酰基l-肉碱与粘酸的盐的制备方法 Expired - Fee Related CN1169781C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000RM000060A IT1316988B1 (it) 2000-02-10 2000-02-10 Procedimento migliorato di preparazione industriale di mucati dellal-carnitina e di alcanoil l-carnitine.
ITRM2000A000060 2000-02-10

Publications (2)

Publication Number Publication Date
CN1398251A CN1398251A (zh) 2003-02-19
CN1169781C true CN1169781C (zh) 2004-10-06

Family

ID=11454414

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018047637A Expired - Fee Related CN1169781C (zh) 2000-02-10 2001-02-09 L-肉碱和烷酰基l-肉碱与粘酸的盐的制备方法

Country Status (19)

Country Link
US (1) US6693215B2 (enExample)
EP (1) EP1257524B1 (enExample)
JP (1) JP4708655B2 (enExample)
KR (1) KR100709629B1 (enExample)
CN (1) CN1169781C (enExample)
AT (1) ATE308509T1 (enExample)
AU (1) AU2001234079A1 (enExample)
CA (1) CA2399501C (enExample)
CZ (1) CZ303031B6 (enExample)
DE (1) DE60114572T2 (enExample)
DK (1) DK1257524T3 (enExample)
ES (1) ES2249411T3 (enExample)
HK (1) HK1052682B (enExample)
HU (1) HU226129B1 (enExample)
IT (1) IT1316988B1 (enExample)
MX (1) MXPA02007682A (enExample)
PL (1) PL201605B1 (enExample)
SK (1) SK287250B6 (enExample)
WO (1) WO2001058850A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118638020B (zh) * 2024-08-08 2024-11-19 杭州海尔希畜牧科技有限公司 L-天门冬氨酸l(-)肉碱(1:1)的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1172394B (it) * 1983-12-28 1987-06-18 Sigma Tau Ind Farmaceuti Sali della l-carnitina e di alcuni alcanoil derivati della l-carnitina e procedimento per la loro preparazione
AU718308B2 (en) 1996-05-31 2000-04-13 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Stable, non-hygroscopic salts of L(-)carnitine and alkanoyl L(-)carnitines, a process for their preparation and solid, orally administrable compositions containing such salts
IT1289974B1 (it) * 1997-02-25 1998-10-19 Aldo Fassi Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine

Also Published As

Publication number Publication date
CN1398251A (zh) 2003-02-19
EP1257524B1 (en) 2005-11-02
WO2001058850A1 (en) 2001-08-16
HU226129B1 (en) 2008-04-28
CZ303031B6 (cs) 2012-03-07
HUP0204378A3 (en) 2005-05-30
PL358098A1 (en) 2004-08-09
SK287250B6 (sk) 2010-04-07
IT1316988B1 (it) 2003-05-26
HUP0204378A2 (hu) 2003-04-28
PL201605B1 (pl) 2009-04-30
ES2249411T3 (es) 2006-04-01
KR100709629B1 (ko) 2007-04-19
AU2001234079A1 (en) 2001-08-20
HK1052682B (zh) 2005-05-06
CA2399501C (en) 2010-06-29
US20030130539A1 (en) 2003-07-10
ATE308509T1 (de) 2005-11-15
DE60114572T2 (de) 2006-07-27
ITRM20000060A1 (it) 2001-08-10
SK11552002A3 (sk) 2002-12-03
US6693215B2 (en) 2004-02-17
DK1257524T3 (da) 2006-02-13
HK1052682A1 (en) 2003-09-26
EP1257524A1 (en) 2002-11-20
JP2003522749A (ja) 2003-07-29
KR20020073543A (ko) 2002-09-26
ITRM20000060A0 (it) 2000-02-10
CA2399501A1 (en) 2001-08-16
JP4708655B2 (ja) 2011-06-22
DE60114572D1 (de) 2005-12-08
MXPA02007682A (es) 2003-01-28
CZ20022533A3 (cs) 2003-02-12

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