DE60113410D1 - Spritzensysteme für lyophilisierte arzneimittel und methode zu deren herstellung - Google Patents

Spritzensysteme für lyophilisierte arzneimittel und methode zu deren herstellung

Info

Publication number
DE60113410D1
DE60113410D1 DE60113410T DE60113410T DE60113410D1 DE 60113410 D1 DE60113410 D1 DE 60113410D1 DE 60113410 T DE60113410 T DE 60113410T DE 60113410 T DE60113410 T DE 60113410T DE 60113410 D1 DE60113410 D1 DE 60113410D1
Authority
DE
Germany
Prior art keywords
lyophilization
drug chamber
plug cap
drug
maintenance sleeve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60113410T
Other languages
English (en)
Other versions
DE60113410T2 (de
Inventor
W Grabenkort
M Farmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hospira Inc
Original Assignee
Hospira Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hospira Inc filed Critical Hospira Inc
Publication of DE60113410D1 publication Critical patent/DE60113410D1/de
Application granted granted Critical
Publication of DE60113410T2 publication Critical patent/DE60113410T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104—Caps for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3106—Plugs for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3123—Details having air entrapping or venting means, e.g. purging channels in pistons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
    • A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE60113410T 2000-05-31 2001-05-23 Spritzensysteme für lyophilisierte arzneimittel und methode zu deren herstellung Expired - Fee Related DE60113410T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US584307 2000-05-31
US09/584,307 US6440101B1 (en) 2000-05-31 2000-05-31 Syringe systems for lyophilized drugs and methods for making the same
PCT/US2001/016803 WO2001091836A2 (en) 2000-05-31 2001-05-23 Syringe systems for lyophilized drugs and methods for making the same

Publications (2)

Publication Number Publication Date
DE60113410D1 true DE60113410D1 (de) 2005-10-20
DE60113410T2 DE60113410T2 (de) 2006-07-06

Family

ID=24336770

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60113410T Expired - Fee Related DE60113410T2 (de) 2000-05-31 2001-05-23 Spritzensysteme für lyophilisierte arzneimittel und methode zu deren herstellung

Country Status (9)

Country Link
US (1) US6440101B1 (de)
EP (1) EP1289583B1 (de)
JP (1) JP2003535624A (de)
AT (1) ATE304380T1 (de)
AU (2) AU6490701A (de)
CA (1) CA2410468A1 (de)
DE (1) DE60113410T2 (de)
ES (1) ES2248338T3 (de)
WO (1) WO2001091836A2 (de)

Families Citing this family (36)

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US6835191B2 (en) 2001-12-21 2004-12-28 3M Innovative Properties Co. Self-venting movable seal and plunger
US7294119B2 (en) * 2004-06-10 2007-11-13 Safety Syringes, Inc. Passive delivery system diluents mixing and delivery
US7727195B2 (en) * 2004-07-01 2010-06-01 West Pharmaceutical Services, Inc. Syringe device having venting system
AT500930B1 (de) * 2004-10-25 2007-03-15 Pharma Consult Ges M B H & Co Verfahren und vorrichtung zum lyophilisieren, rekonstituieren und verabreichen eines rekonstituierten wirkstoffes
AU2005312301B2 (en) 2004-12-01 2012-02-09 Acushot Inc. Needle-free injector
US20060157507A1 (en) * 2004-12-30 2006-07-20 Chang Byeong S Multi-functional container closure delivery system
US20060144869A1 (en) * 2004-12-30 2006-07-06 Chang Byeong S Container closure delivery system
US7959600B2 (en) 2004-12-30 2011-06-14 Byeong S. Chang Container closure delivery system
DE502005005547D1 (de) * 2005-07-15 2008-11-13 Dentaco Gmbh Pipettiervorrichtung
DE102005038458A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter ohne Bypass im zylindrischen Körper
DE102005038497A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter ohne Bypass
DE102005038368A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter zur Lyophilisation, Verfahren zu dessen Befüllung und dessen Verwendung
DE102005038495A1 (de) * 2005-08-13 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Doppelkammer-Behälter und Verfahren zu dessen Befüllung
WO2007093307A1 (de) * 2006-02-14 2007-08-23 Arzneimittel Gmbh Spritze
NZ573048A (en) 2006-05-25 2011-08-26 Bayer Healthcare Llc Reconstitution device
CN101500631A (zh) * 2006-08-09 2009-08-05 药物混合系统股份公司 带有活塞的注射器
JP4994775B2 (ja) 2006-10-12 2012-08-08 日本コヴィディエン株式会社 針先保護具
JP5113377B2 (ja) * 2006-12-20 2013-01-09 武蔵エンジニアリング株式会社 閉蓋具および液体材料貯留容器
US9044378B2 (en) 2007-05-31 2015-06-02 Safety Syringes, Inc. Anti-needle stick safety device or system for use with drugs requiring reconstitution
WO2009030342A1 (de) * 2007-08-28 2009-03-12 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Aufnahmevorrichtung
ES2589322T3 (es) 2008-02-11 2016-11-11 Safety Syringes, Inc. Jeringa con protector de seguridad de aguja y clip para evitar la liberación del protector durante un proceso de reconstitución
DE102008031809A1 (de) * 2008-06-27 2009-12-31 Optima Group Pharma Gmbh Halterung
US8371039B2 (en) * 2009-12-30 2013-02-12 Baxter International Inc. Thermal shielding to optimize lyophilization process for pre-filled syringes or vials
CN103582473B (zh) 2011-01-10 2016-11-02 拜昂·塞翁·常 紧凑药物复原装置和方法
ES2662356T3 (es) 2011-04-27 2018-04-06 Kpr U.S., Llc Conjuntos de catéter IV de seguridad
GB201113606D0 (en) * 2011-08-05 2011-09-21 Norbrook Lab Ltd Dual chamber syringe
US8715250B2 (en) 2011-09-26 2014-05-06 Covidien Lp Safety catheter and needle assembly
US8628497B2 (en) 2011-09-26 2014-01-14 Covidien Lp Safety catheter
WO2013056223A1 (en) 2011-10-14 2013-04-18 Covidien Lp Safety iv catheter assembly
CN102961803B (zh) * 2012-10-30 2015-01-21 无锡耐思生物科技有限公司 一次性使用预灌封注射器
WO2015038281A1 (en) 2013-09-16 2015-03-19 Zoetis Llc Assembly for sequentially delivering substances, and associated methods
MX2017003095A (es) 2014-09-09 2018-01-26 Seon Chang Byeong Dispositivo y método de entrega de solución.
CA3056099C (en) * 2015-01-16 2021-10-19 Becton Dickinson France Drug storage and dispensing system for pre-filled containers
JP2022543820A (ja) * 2019-08-06 2022-10-14 マイクロベンション インコーポレイテッド 注射器
JP2022012330A (ja) * 2020-07-01 2022-01-17 テルモ株式会社 プレフィルドシリンジ、シリンジ組立体、プレフィルドシリンジの製造方法及び表面積増加方法
WO2024059819A2 (en) 2022-09-15 2024-03-21 Tff Pharmaceuticals, Inc. Compositions of cannabinoids for delivery by inhalation

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US3810469A (en) 1972-05-24 1974-05-14 Ampoules Inc Multiple compartment hypodermic devices
US4254768A (en) 1979-09-14 1981-03-10 Ty Perla J Hypodermic syringe
IT8222194V0 (it) 1982-06-18 1982-06-18 Edwards Alto Vuoto Spa Dispositivo per il caricamento delle piastre porta-prodotto di una camera di liofilizzazione mediante impiego di contenitori preposizionati ad altezza costante.
US4693706A (en) * 1986-08-11 1987-09-15 Mark L. Anderson Two compartment mixing syringe
US5364369A (en) * 1987-07-08 1994-11-15 Reynolds David L Syringe
SE9201247D0 (sv) 1992-04-21 1992-04-21 Kabi Pharmacia Ab Injection device
US5531683A (en) * 1992-08-13 1996-07-02 Science Incorporated Mixing and delivery syringe assembly
US5522804A (en) * 1994-02-15 1996-06-04 Lynn; Lawrence A. Aspiration, mixing, and injection syringe
DE4445969C1 (de) * 1994-12-22 1996-03-14 Schott Glaswerke Spritzenzylinder für eine Zweikammer-Fertigspritze, Zweikammer-Fertigspritze und Verfahren zum Herstellen und Füllen derselben
US5685846A (en) * 1995-02-27 1997-11-11 Schott Parenta Systems, Inc. Dual chamber internal by-pass syringe assembly
US5779668A (en) 1995-03-29 1998-07-14 Abbott Laboratories Syringe barrel for lyophilization, reconstitution and administration
DE19638940C2 (de) * 1996-09-23 1999-01-07 Vetter & Co Apotheker Vorgefüllte Spritze für medizinische Zwecke
US5865803A (en) * 1997-05-19 1999-02-02 Major; Miklos Syringe device having a vented piston
US5971953A (en) * 1998-01-09 1999-10-26 Bachynsky; Nicholas Dual chamber syringe apparatus

Also Published As

Publication number Publication date
EP1289583B1 (de) 2005-09-14
JP2003535624A (ja) 2003-12-02
ES2248338T3 (es) 2006-03-16
WO2001091836A3 (en) 2002-03-28
ATE304380T1 (de) 2005-09-15
AU2001264907B2 (en) 2005-07-21
AU6490701A (en) 2001-12-11
WO2001091836A2 (en) 2001-12-06
CA2410468A1 (en) 2001-12-06
DE60113410T2 (de) 2006-07-06
EP1289583A2 (de) 2003-03-12
US6440101B1 (en) 2002-08-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee