DE60100238D1 - Synthese von 3,6-Dialkyl-5,6-Dihydro-4-Hydroxy-2H-Pyran-2-one - Google Patents

Synthese von 3,6-Dialkyl-5,6-Dihydro-4-Hydroxy-2H-Pyran-2-one

Info

Publication number
DE60100238D1
DE60100238D1 DE60100238T DE60100238T DE60100238D1 DE 60100238 D1 DE60100238 D1 DE 60100238D1 DE 60100238 T DE60100238 T DE 60100238T DE 60100238 T DE60100238 T DE 60100238T DE 60100238 D1 DE60100238 D1 DE 60100238D1
Authority
DE
Germany
Prior art keywords
pyran
dialkyl
dihydro
hydroxy
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60100238T
Other languages
English (en)
Other versions
DE60100238T2 (de
Inventor
Peter John Harrington
Lewis M Hodges
Kurt Puentener
Michelangelo Scalone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE60100238D1 publication Critical patent/DE60100238D1/de
Application granted granted Critical
Publication of DE60100238T2 publication Critical patent/DE60100238T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Epoxy Compounds (AREA)
DE60100238T 2000-02-04 2001-01-26 Synthese von 3,6-Dialkyl-5,6-Dihydro-4-Hydroxy-2H-Pyran-2-one Expired - Lifetime DE60100238T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18057800P 2000-02-04 2000-02-04
US180578P 2000-02-04

Publications (2)

Publication Number Publication Date
DE60100238D1 true DE60100238D1 (de) 2003-06-12
DE60100238T2 DE60100238T2 (de) 2004-04-01

Family

ID=22660964

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60100238T Expired - Lifetime DE60100238T2 (de) 2000-02-04 2001-01-26 Synthese von 3,6-Dialkyl-5,6-Dihydro-4-Hydroxy-2H-Pyran-2-one

Country Status (12)

Country Link
US (1) US6552204B1 (de)
EP (1) EP1127886B1 (de)
JP (3) JP2001220387A (de)
KR (1) KR100509081B1 (de)
CN (1) CN1193992C (de)
AT (1) ATE239716T1 (de)
CA (1) CA2333192C (de)
DE (1) DE60100238T2 (de)
DK (1) DK1127886T3 (de)
ES (1) ES2197128T3 (de)
JO (1) JO2249B1 (de)
MX (1) MXPA01001187A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6552204B1 (en) * 2000-02-04 2003-04-22 Roche Colorado Corporation Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one
US8932136B2 (en) 2000-08-25 2015-01-13 Opentv, Inc. Method and system for initiating an interactive game
JPWO2004065346A1 (ja) * 2003-01-21 2006-05-18 住友化学株式会社 （−）−テトラヒドロリプスタチンおよびその中間体の製造方法
EP1651627A2 (de) * 2003-07-15 2006-05-03 Ranbaxy Laboratories Limited Verfahren zur herstellung von oxetan-2-one
CA2572845A1 (en) 2004-07-08 2006-02-16 Merck & Co., Inc. Formation of tetra-substituted enamides and stereoselective reduction thereof
WO2006090377A1 (en) * 2005-02-22 2006-08-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem One-pot non-symmetric heterobifunctional coupling of organic molecules through malonic acid derivatives
EP1868717B1 (de) * 2005-04-15 2013-03-27 DSM IP Assets B.V. Herstellung von thiolactonen
US20080113325A1 (en) * 2006-11-09 2008-05-15 Sony Ericsson Mobile Communications Ab Tv out enhancements to music listening
CN101066924B (zh) * 2007-06-08 2011-01-12 中国科学院上海有机化学研究所 2-己基-3-羟基-5-r1氧基十六羧酸r2酯,制备方法及用于制备减肥药物奥利司他的用途
KR101076680B1 (ko) * 2007-11-01 2011-10-26 한미홀딩스 주식회사 (6ｒ)-3-헥실-4-히드록시-6-운데실-5,6-다이히드로피란-2-온의 제조방법 및 이에 사용되는 중간체
CA2744511A1 (en) * 2008-12-16 2010-06-24 F.Hoffmann-La Roche Ag Process for the preparation of pyrollidine-3-carboxylic acids
JP5933529B2 (ja) * 2010-05-21 2016-06-08 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ ルテニウムをベースとする錯体
EP2585474B1 (de) * 2010-06-22 2015-10-07 Firmenich SA Rutheniumbasierte komplexe
US8598925B1 (en) * 2012-07-16 2013-12-03 Nanowave Technologies Inc. Frequency determination circuit and method
JP7161316B2 (ja) 2018-06-11 2022-10-26 クノールブレムゼ商用車システムジャパン株式会社 不純物分離装置
WO2024008605A2 (en) 2022-07-04 2024-01-11 F. Hoffmann-La Roche Ag Process for the preparation of [ru(oac)2(ligand)] catalysts

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3620467A1 (de) * 1985-06-20 1987-01-02 Ciba Geigy Ag Verfahren zur herstellung von (beta)-lactamen und (beta)-lactame
ES2021058B3 (es) * 1986-10-24 1991-10-16 Merck & Co Inc Procedimiento para la sintesis de una azetidinona quiral.
EP0333268A1 (de) * 1988-03-18 1989-09-20 Merck & Co. Inc. Verfahren zur Synthese eines chiralen 3-beta-Wasserstoff-(3R) 4-aroyloxyazetidinons
ATE128140T1 (de) * 1989-05-18 1995-10-15 Hoffmann La Roche Phosphorverbindungen.
CA2035972C (en) * 1990-02-23 2006-07-11 Martin Karpf Process for the preparation of oxetanones
JPH04316538A (ja) * 1991-01-22 1992-11-06 Chisso Corp 光学活性３，５−アンチ−ジヒドロキシカルボン酸エステル誘導体の製造法
WO1992014692A1 (en) * 1991-02-11 1992-09-03 Rhone-Poulenc Rorer International (Holdings) Inc. Enantioselective preparation of acetylenic or olefinic substituted cycloalkenyl dihydroxybutyrates and 4-hydroxy-tetrahydropyran-2-ones
DE19636974A1 (de) * 1996-09-12 1998-03-19 Hoechst Ag 2-Cyano-3,5-dihydroxy-hex-2-en- carbonsäureamidderivate
JP3445074B2 (ja) * 1996-09-20 2003-09-08 高砂香料工業株式会社 ルテニウム−ホスフィン錯体の製造方法
CA2294293A1 (en) * 1997-07-11 1999-01-21 Pharmacia & Upjohn Company Thiadiazolyl and oxadiazolyl phenyl oxazolidinone antibacterial agents
HU228986B1 (en) * 1997-09-11 2013-07-29 Upjohn Co Process to produce 4-hydroxy-2-oxo-pyrane derivatives useful as protease inhibitors
US6552204B1 (en) * 2000-02-04 2003-04-22 Roche Colorado Corporation Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one

Also Published As

Publication number Publication date
JP2009173635A (ja) 2009-08-06
CN1193992C (zh) 2005-03-23
JP2004346078A (ja) 2004-12-09
US6552204B1 (en) 2003-04-22
JP4666454B2 (ja) 2011-04-06
DK1127886T3 (da) 2003-09-01
KR100509081B1 (ko) 2005-08-18
CA2333192A1 (en) 2001-08-04
JO2249B1 (en) 2004-10-07
MXPA01001187A (es) 2002-06-04
EP1127886B1 (de) 2003-05-07
ATE239716T1 (de) 2003-05-15
DE60100238T2 (de) 2004-04-01
JP5173775B2 (ja) 2013-04-03
CN1319596A (zh) 2001-10-31
JP2001220387A (ja) 2001-08-14
CA2333192C (en) 2007-01-23
EP1127886A1 (de) 2001-08-29
KR20010078336A (ko) 2001-08-20
ES2197128T3 (es) 2004-01-01

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