DE60038386D1 - Stabile proteinlösung abgefüllt in einem behältnis aus hydrophobem harz und eine methode zur stabilisierung derselben - Google Patents

Stabile proteinlösung abgefüllt in einem behältnis aus hydrophobem harz und eine methode zur stabilisierung derselben

Info

Publication number
DE60038386D1
DE60038386D1 DE60038386T DE60038386T DE60038386D1 DE 60038386 D1 DE60038386 D1 DE 60038386D1 DE 60038386 T DE60038386 T DE 60038386T DE 60038386 T DE60038386 T DE 60038386T DE 60038386 D1 DE60038386 D1 DE 60038386D1
Authority
DE
Germany
Prior art keywords
protein solution
hydrophobic resin
stabilizing
reservoir
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60038386T
Other languages
English (en)
Other versions
DE60038386T2 (de
Inventor
Nobuyuki Suzuki
Naoki Mitsui
Takaya Hiraishi
Yoshirou Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of DE60038386D1 publication Critical patent/DE60038386D1/de
Application granted granted Critical
Publication of DE60038386T2 publication Critical patent/DE60038386T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Non-Alcoholic Beverages (AREA)
DE60038386T 1999-09-08 2000-09-08 Stabile proteinlösung abgefüllt in einem behältnis aus hydrophobem harz und eine methode zur stabilisierung derselben Expired - Lifetime DE60038386T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP25489699 1999-09-08
JP25489699 1999-09-08
PCT/JP2000/006144 WO2001017542A1 (fr) 1999-09-08 2000-09-08 Preparation de solution de proteines et procede de stabilisation associe

Publications (2)

Publication Number Publication Date
DE60038386D1 true DE60038386D1 (de) 2008-04-30
DE60038386T2 DE60038386T2 (de) 2009-04-23

Family

ID=17271358

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60038386T Expired - Lifetime DE60038386T2 (de) 1999-09-08 2000-09-08 Stabile proteinlösung abgefüllt in einem behältnis aus hydrophobem harz und eine methode zur stabilisierung derselben

Country Status (8)

Country Link
US (1) US7253142B1 (de)
EP (1) EP1232753B1 (de)
JP (3) JP5450508B2 (de)
AT (1) ATE389414T1 (de)
AU (1) AU6875900A (de)
DE (1) DE60038386T2 (de)
TW (1) TWI245645B (de)
WO (1) WO2001017542A1 (de)

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WO2004082708A2 (en) * 2003-03-18 2004-09-30 Novo Nordisk Health Care Ag Liquid, aqueous, pharmaceutical compositions of factor vii polypeptides
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
DE602004025100D1 (de) * 2003-05-23 2010-03-04 Novo Nordisk Healthcare Ag Stabilisierung von proteinen in lösung
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EP3907236A1 (de) 2016-12-22 2021-11-10 Zeon Corporation Oligopeptidsuchverfahren, oligopeptid, modifiziertes peptid und immuntestverfahren
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Also Published As

Publication number Publication date
JP5450508B2 (ja) 2014-03-26
JP2016056176A (ja) 2016-04-21
ATE389414T1 (de) 2008-04-15
EP1232753A4 (de) 2004-08-11
WO2001017542A1 (fr) 2001-03-15
JP6134370B2 (ja) 2017-05-24
TWI245645B (en) 2005-12-21
JP6076226B2 (ja) 2017-02-08
EP1232753A1 (de) 2002-08-21
DE60038386T2 (de) 2009-04-23
EP1232753B1 (de) 2008-03-19
JP2014051502A (ja) 2014-03-20
AU6875900A (en) 2001-04-10
JP2011168610A (ja) 2011-09-01
US7253142B1 (en) 2007-08-07

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Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: WATANABE, YOSHIROU, TOKYO, JP

Inventor name: HIRAISHI, TAKAYA, TOKYO, JP

Inventor name: MITSUI, NAOKI, TOKYO, JP

Inventor name: SUZUKI, NOBUYUKI, TOKYO, JP

8364 No opposition during term of opposition