DE60034370T2 - Verfahren und vorrichtung zur analyse von zellen in einer vollblutprobe - Google Patents
Verfahren und vorrichtung zur analyse von zellen in einer vollblutprobe Download PDFInfo
- Publication number
- DE60034370T2 DE60034370T2 DE60034370T DE60034370T DE60034370T2 DE 60034370 T2 DE60034370 T2 DE 60034370T2 DE 60034370 T DE60034370 T DE 60034370T DE 60034370 T DE60034370 T DE 60034370T DE 60034370 T2 DE60034370 T2 DE 60034370T2
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- Prior art keywords
- cell
- sample
- blood cells
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
- G01N2015/139—Measuring the ratio of AC/DC impedances
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/808—Optical sensing apparatus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
Landscapes
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Optical Measuring Cells (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US251019 | 1999-02-16 | ||
| US09/251,019 US6228652B1 (en) | 1999-02-16 | 1999-02-16 | Method and apparatus for analyzing cells in a whole blood sample |
| PCT/US2000/002715 WO2000049385A2 (en) | 1999-02-16 | 2000-02-03 | Method and apparatus for analyzing cells in a whole blood sample |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60034370D1 DE60034370D1 (de) | 2007-05-24 |
| DE60034370T2 true DE60034370T2 (de) | 2007-12-20 |
Family
ID=22950141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60034370T Expired - Lifetime DE60034370T2 (de) | 1999-02-16 | 2000-02-03 | Verfahren und vorrichtung zur analyse von zellen in einer vollblutprobe |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6228652B1 (enExample) |
| EP (1) | EP1250585B1 (enExample) |
| JP (1) | JP4468590B2 (enExample) |
| DE (1) | DE60034370T2 (enExample) |
| WO (1) | WO2000049385A2 (enExample) |
Families Citing this family (159)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6060322A (en) * | 1998-10-20 | 2000-05-09 | Coulter International Corp. | Method for identification of reticulated cells |
| JP3817091B2 (ja) * | 1999-07-02 | 2006-08-30 | テルモ株式会社 | 細胞数測定装置 |
| AU8026100A (en) * | 1999-10-15 | 2001-04-30 | The Administrators Of The Tulane Eductional Fund | Device for and method of simultaneously measuring light scatter from multiple liquid samples |
| US6587792B1 (en) * | 2000-01-11 | 2003-07-01 | Richard A. Thomas | Nuclear packing efficiency |
| US6646742B1 (en) * | 2000-02-19 | 2003-11-11 | Mwi, Inc. | Optical device and method for multi-angle laser light scatter |
| US6624621B2 (en) * | 2000-04-03 | 2003-09-23 | Howard L. North, Jr. | Particle counter volume sensor |
| US6890489B2 (en) * | 2000-04-26 | 2005-05-10 | Rheodyne, L.P. | Mass rate attenuator |
| US7630063B2 (en) * | 2000-08-02 | 2009-12-08 | Honeywell International Inc. | Miniaturized cytometer for detecting multiple species in a sample |
| US6784981B1 (en) * | 2000-06-02 | 2004-08-31 | Idexx Laboratories, Inc. | Flow cytometry-based hematology system |
| JP4494606B2 (ja) * | 2000-08-11 | 2010-06-30 | 浜松ホトニクス株式会社 | 液体含有物質分析装置及び液体含有物質分析方法 |
| US20020086431A1 (en) * | 2000-08-21 | 2002-07-04 | Markham Walter Bruce | Sample preparation and slide plating apparatus and method |
| US20020028434A1 (en) * | 2000-09-06 | 2002-03-07 | Guava Technologies, Inc. | Particle or cell analyzer and method |
| JP4759188B2 (ja) * | 2000-09-18 | 2011-08-31 | シスメックス株式会社 | 血球検出器及びそれを備えた血液分析装置 |
| US6716633B2 (en) | 2000-09-18 | 2004-04-06 | Sysmex Corporation | Blood cell detector, blood analyzer and blood analyzing method using the detector |
| US7279883B2 (en) | 2001-01-23 | 2007-10-09 | Lydia L. Sohn | Particle analyzer and methods for use thereof |
| US6793642B2 (en) * | 2001-05-07 | 2004-09-21 | Biomed Solutions, Llc | Flow cytometer |
| US6743190B2 (en) * | 2001-05-07 | 2004-06-01 | Biomed Solutions L.L.C. | Flow cytometer shunt |
| US20030027347A1 (en) * | 2001-05-25 | 2003-02-06 | Phyllis Shapiro | Automated method for correcting blood analysis parameter results affected by interference from exogenous blood substitutes in whole blood, plasma, and serum |
| DE10128449B4 (de) * | 2001-06-12 | 2004-07-15 | Robert Bosch Gmbh | Vorrichtung und Verfahren zur Prüfung eines Materials |
| US6472215B1 (en) * | 2001-07-27 | 2002-10-29 | Coulter International Corp. | Method of analyzing nucleated red blood cells in a blood sample |
| EP1412740B1 (en) * | 2001-07-27 | 2015-07-08 | Beckman Coulter, Inc. | Method for measurement of nucleated red blood cells |
| US6410330B1 (en) * | 2001-07-27 | 2002-06-25 | Coulter International Corp. | Method for measurement of nucleated red blood cells |
| US6803208B2 (en) * | 2001-07-30 | 2004-10-12 | The United States Of America As Represented By The Secretary Of The Navy | Automated epifluorescence microscopy for detection of bacterial contamination in platelets |
| US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
| US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
| US6723563B2 (en) | 2001-12-03 | 2004-04-20 | Streck Laboratories Inc. | Hematology reference control |
| US6653137B2 (en) | 2001-12-03 | 2003-11-25 | Streck Laboratories Inc. | Hematology reference control |
| ATE339687T1 (de) * | 2002-05-22 | 2006-10-15 | Sysmex Corp | Immunologische verfahren, vorrichtungen und reagenzien |
| US7569393B2 (en) | 2002-06-28 | 2009-08-04 | International Technidyne Corporation | Analytical test cartridge; and, methods |
| JP4299597B2 (ja) * | 2002-07-29 | 2009-07-22 | シスメックス株式会社 | 血液分析装置及び方法 |
| US6794877B2 (en) * | 2002-07-31 | 2004-09-21 | International Technidyne Corporation | Apparatus and method for analytical determinations |
| US6743634B2 (en) * | 2002-08-23 | 2004-06-01 | Coulter International Corp. | Method and apparatus for differentiating blood cells using back-scatter |
| US20040166540A1 (en) * | 2003-02-24 | 2004-08-26 | Sysmex Corporation | Methods of detecting CD34 positive and negative hematopoietic stem cells in human samples |
| US20040219612A1 (en) * | 2003-05-02 | 2004-11-04 | Beckman Coulter, Inc. | Methods for detecting intracellular defensins in various leukocyte subpopulations |
| US20040228766A1 (en) * | 2003-05-14 | 2004-11-18 | Witty Thomas R. | Point of care diagnostic platform |
| US20040228765A1 (en) * | 2003-05-14 | 2004-11-18 | Witty Thomas R. | Point of care diagnostic platform |
| JP2005024472A (ja) * | 2003-07-04 | 2005-01-27 | Sysmex Corp | 幼若血小板測定装置 |
| EP1682865B1 (en) * | 2003-10-12 | 2018-08-15 | Beckman Coulter, Inc. | Method of using a reference control composition for measurement of nucleated red blood cells |
| US7095492B2 (en) * | 2003-12-19 | 2006-08-22 | Beckman Coulter, Inc. | Method and apparatus for measuring cell-by-cell hemoglobin |
| CA2551484C (en) * | 2003-12-24 | 2015-03-31 | Glycofi, Inc. | Methods for eliminating mannosylphosphorylation of glycans in the production of glycoproteins |
| JP4435581B2 (ja) * | 2004-01-07 | 2010-03-17 | シスメックス株式会社 | 免疫測定装置および方法 |
| JP4911601B2 (ja) * | 2004-02-10 | 2012-04-04 | ベックマン コールター， インコーポレイテッド | 有核赤血球細胞の計測方法 |
| US7208319B2 (en) * | 2004-02-10 | 2007-04-24 | Beckman Coulter, Inc. | Method of measurement of nucleated red blood cells |
| JP4417143B2 (ja) * | 2004-03-11 | 2010-02-17 | シスメックス株式会社 | 試料分析装置、プログラムおよびそのプログラムを記録した記録媒体 |
| US7625712B2 (en) | 2004-05-21 | 2009-12-01 | Beckman Coulter, Inc. | Method for a fully automated monoclonal antibody-based extended differential |
| US7674598B2 (en) * | 2004-05-21 | 2010-03-09 | Beckman Coulter, Inc. | Method for a fully automated monoclonal antibody-based extended differential |
| US7075647B2 (en) * | 2004-06-30 | 2006-07-11 | Beckman Coulter, Inc. | Back-scatter detection in flow cytometers |
| US7340957B2 (en) * | 2004-07-29 | 2008-03-11 | Los Alamos National Security, Llc | Ultrasonic analyte concentration and application in flow cytometry |
| FR2873813B1 (fr) * | 2004-07-30 | 2006-11-17 | Abx Sa | Procede et dispositif de caracterisation des composants cellulaires d'un liquide biologique |
| WO2006013942A1 (ja) * | 2004-08-04 | 2006-02-09 | Matsushita Electric Industrial Co., Ltd. | 侵入検出装置 |
| US8685711B2 (en) * | 2004-09-28 | 2014-04-01 | Singulex, Inc. | Methods and compositions for highly sensitive detection of molecules |
| US7392908B2 (en) * | 2005-01-12 | 2008-07-01 | Beckman Coulter, Inc. | Methods and apparatus for sorting particles hydraulically |
| US7678578B2 (en) * | 2005-02-07 | 2010-03-16 | Beckman Coulter, Inc. | Cell permeabilization and stabilization reagent and method of use |
| US20070077177A1 (en) * | 2005-03-16 | 2007-04-05 | Klaus Witt | Stimulated detection of sample compounds |
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- 2000-02-03 WO PCT/US2000/002715 patent/WO2000049385A2/en not_active Ceased
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| WO2000049385A2 (en) | 2000-08-24 |
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| DE60034370D1 (de) | 2007-05-24 |
| JP4468590B2 (ja) | 2010-05-26 |
| EP1250585B1 (en) | 2007-04-11 |
| EP1250585A2 (en) | 2002-10-23 |
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