DE60028534D1 - Binärsonde, klammerzusammensetzung und verfahren zum zielhybridisierungsnachweis - Google Patents

Binärsonde, klammerzusammensetzung und verfahren zum zielhybridisierungsnachweis

Info

Publication number
DE60028534D1
DE60028534D1 DE60028534T DE60028534T DE60028534D1 DE 60028534 D1 DE60028534 D1 DE 60028534D1 DE 60028534 T DE60028534 T DE 60028534T DE 60028534 T DE60028534 T DE 60028534T DE 60028534 D1 DE60028534 D1 DE 60028534D1
Authority
DE
Germany
Prior art keywords
detection
probe
target hybridization
hybridization procedure
procedure method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60028534T
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English (en)
Other versions
DE60028534T2 (de
Inventor
J Livak
Michael Egholm
W Hunkapiller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Application granted granted Critical
Publication of DE60028534D1 publication Critical patent/DE60028534D1/de
Publication of DE60028534T2 publication Critical patent/DE60028534T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6818Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
DE60028534T 1999-01-15 2000-01-14 Binärsonde, klammerzusammensetzung und verfahren zum zielhybridisierungsnachweis Expired - Lifetime DE60028534T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/232,000 US6432642B1 (en) 1999-01-15 1999-01-15 Binary probe and clamp composition and methods for a target hybridization detection
US232000 1999-01-15
PCT/US2000/000972 WO2000041549A2 (en) 1999-01-15 2000-01-14 Binary probe and clamp composition and methods for target hybridization detection

Publications (2)

Publication Number Publication Date
DE60028534D1 true DE60028534D1 (de) 2006-07-20
DE60028534T2 DE60028534T2 (de) 2007-06-06

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE60028534T Expired - Lifetime DE60028534T2 (de) 1999-01-15 2000-01-14 Binärsonde, klammerzusammensetzung und verfahren zum zielhybridisierungsnachweis

Country Status (8)

Country Link
US (4) US6432642B1 (de)
EP (1) EP1141387B1 (de)
JP (3) JP4644370B2 (de)
AT (1) ATE329056T1 (de)
AU (1) AU771650B2 (de)
CA (1) CA2360543C (de)
DE (1) DE60028534T2 (de)
WO (1) WO2000041549A2 (de)

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CN106715768B (zh) 2014-07-30 2020-06-16 哈佛学院院长及董事 用于测定核酸的系统和方法
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US11788123B2 (en) 2017-05-26 2023-10-17 President And Fellows Of Harvard College Systems and methods for high-throughput image-based screening
KR101899371B1 (ko) * 2017-07-25 2018-10-29 (주)엔바이오텍 핵산 복합체 페어, 핵산 복합체 페어를 포함하는 pcr용 키트, 및 핵산 복합체 페어를 이용한 타겟 검출 방법
KR102262260B1 (ko) * 2018-02-08 2021-06-09 주식회사 시선테라퓨틱스 엔도좀 탈출능을 갖는 펩티드 핵산 복합체 및 이의 용도
CN110542674B (zh) * 2019-09-19 2021-10-22 济南大学 一种检测谷胱甘肽的生物传感器及其制备方法
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Also Published As

Publication number Publication date
US8067165B2 (en) 2011-11-29
ATE329056T1 (de) 2006-06-15
EP1141387A2 (de) 2001-10-10
CA2360543C (en) 2009-03-31
WO2000041549A2 (en) 2000-07-20
US20100291557A1 (en) 2010-11-18
US20060035217A1 (en) 2006-02-16
DE60028534T2 (de) 2007-06-06
US6432642B1 (en) 2002-08-13
JP4644370B2 (ja) 2011-03-02
JP2002534100A (ja) 2002-10-15
AU2850400A (en) 2000-08-01
EP1141387B1 (de) 2006-06-07
WO2000041549A3 (en) 2000-11-30
JP2005160489A (ja) 2005-06-23
US7057025B2 (en) 2006-06-06
JP2009017882A (ja) 2009-01-29
US20070026429A1 (en) 2007-02-01
AU771650B2 (en) 2004-04-01
CA2360543A1 (en) 2000-07-20

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Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US

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