ATE455867T1 - Echtzeit-pcr unter zusatz von pyrophosphatase - Google Patents

Echtzeit-pcr unter zusatz von pyrophosphatase

Info

Publication number
ATE455867T1
ATE455867T1 AT05019405T AT05019405T ATE455867T1 AT E455867 T1 ATE455867 T1 AT E455867T1 AT 05019405 T AT05019405 T AT 05019405T AT 05019405 T AT05019405 T AT 05019405T AT E455867 T1 ATE455867 T1 AT E455867T1
Authority
AT
Austria
Prior art keywords
pyrophosphatase
real
addition
time pcr
nucleic acid
Prior art date
Application number
AT05019405T
Other languages
English (en)
Inventor
Inga Boell
Anja Degen
Dieter Heindl
Gregor Sagner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE455867T1 publication Critical patent/ATE455867T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6818Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT05019405T 2004-09-09 2005-09-07 Echtzeit-pcr unter zusatz von pyrophosphatase ATE455867T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04021399 2004-09-09

Publications (1)

Publication Number Publication Date
ATE455867T1 true ATE455867T1 (de) 2010-02-15

Family

ID=34926467

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05019405T ATE455867T1 (de) 2004-09-09 2005-09-07 Echtzeit-pcr unter zusatz von pyrophosphatase

Country Status (7)

Country Link
US (1) US20060051796A1 (de)
JP (1) JP2006075167A (de)
CN (1) CN100478453C (de)
AT (1) ATE455867T1 (de)
CA (1) CA2515242C (de)
DE (1) DE602005019005D1 (de)
ES (1) ES2338662T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008080254A1 (en) * 2006-12-29 2008-07-10 Honeywell International Inc. Reaction buffer for microarray
CN107011428B (zh) * 2008-03-28 2022-02-25 Mdna生命科学有限公司 异常线粒体dna、相关的融合转录物及其杂交探针
US8346485B2 (en) 2008-11-25 2013-01-01 Quest Diagnostics Investments Incorporated Methods and apparatuses for estimating initial target nucleic acid concentration in a sample by modeling background signal and cycle-dependent amplification efficiency of a polymerase chain reaction
EP3375890B1 (de) 2009-09-10 2020-01-22 DiaSorin S.p.A. Verfahren und vorrichtungen zur bestimmung einer übersprechkorrection bei der nukleinsäureamplifikation
KR20240171383A (ko) * 2023-05-30 2024-12-09 홍익대학교 산학협력단 전기화학적 방식을 이용한 중합효소 연쇄 반응의 피로인산 이온 농도 변화 측정 방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618711A (en) * 1986-08-22 1997-04-08 Hoffmann-La Roche Inc. Recombinant expression vectors and purification methods for Thermus thermophilus DNA polymerase
US5498523A (en) * 1988-07-12 1996-03-12 President And Fellows Of Harvard College DNA sequencing with pyrophosphatase
US5118801A (en) * 1988-09-30 1992-06-02 The Public Health Research Institute Nucleic acid process containing improved molecular switch
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5538848A (en) * 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
US5773258A (en) * 1995-08-25 1998-06-30 Roche Molecular Systems, Inc. Nucleic acid amplification using a reversibly inactivated thermostable enzyme
US6174670B1 (en) * 1996-06-04 2001-01-16 University Of Utah Research Foundation Monitoring amplification of DNA during PCR
DE19653494A1 (de) * 1996-12-20 1998-06-25 Svante Dr Paeaebo Verfahren zur entkoppelten, direkten, exponentiellen Amplifikation und Sequenzierung von DNA Molekülen unter Zugabe einer zweiten thermostabilen DNA Polymerase und dessen Anwendung
ATE353974T1 (de) * 2000-04-03 2007-03-15 Corixa Corp Verfahren, zusammensetzungen und kits zur identifizierung und überwachung von brustkrebs
GB0110501D0 (en) * 2001-04-30 2001-06-20 Secr Defence Brit Amplification process
US20040170981A1 (en) * 2003-02-10 2004-09-02 Mckenney Keith Real-time polymerase chain reaction using large target amplicons

Also Published As

Publication number Publication date
DE602005019005D1 (de) 2010-03-11
CA2515242C (en) 2010-11-02
CN1746314A (zh) 2006-03-15
US20060051796A1 (en) 2006-03-09
ES2338662T3 (es) 2010-05-11
JP2006075167A (ja) 2006-03-23
CA2515242A1 (en) 2006-03-09
CN100478453C (zh) 2009-04-15

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