ATE329056T1 - Binärsonde, klammerzusammensetzung und verfahren zum zielhybridisierungsnachweis - Google Patents

Binärsonde, klammerzusammensetzung und verfahren zum zielhybridisierungsnachweis

Info

Publication number
ATE329056T1
ATE329056T1 AT00906924T AT00906924T ATE329056T1 AT E329056 T1 ATE329056 T1 AT E329056T1 AT 00906924 T AT00906924 T AT 00906924T AT 00906924 T AT00906924 T AT 00906924T AT E329056 T1 ATE329056 T1 AT E329056T1
Authority
AT
Austria
Prior art keywords
probe
detection
target hybridization
hybridization detection
clamps
Prior art date
Application number
AT00906924T
Other languages
English (en)
Inventor
Kenneth J Livak
Michael Egholm
Michael W Hunkapiller
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Application granted granted Critical
Publication of ATE329056T1 publication Critical patent/ATE329056T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT00906924T 1999-01-15 2000-01-14 Binärsonde, klammerzusammensetzung und verfahren zum zielhybridisierungsnachweis ATE329056T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/232,000 US6432642B1 (en) 1999-01-15 1999-01-15 Binary probe and clamp composition and methods for a target hybridization detection

Publications (1)

Publication Number Publication Date
ATE329056T1 true ATE329056T1 (de) 2006-06-15

Family

ID=22871476

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00906924T ATE329056T1 (de) 1999-01-15 2000-01-14 Binärsonde, klammerzusammensetzung und verfahren zum zielhybridisierungsnachweis

Country Status (8)

Country Link
US (4) US6432642B1 (de)
EP (1) EP1141387B1 (de)
JP (3) JP4644370B2 (de)
AT (1) ATE329056T1 (de)
AU (1) AU771650B2 (de)
CA (1) CA2360543C (de)
DE (1) DE60028534T2 (de)
WO (1) WO2000041549A2 (de)

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US7588921B1 (en) * 2004-09-22 2009-09-15 University Of Central Florida Research Foundation, Inc. Messenger RNA profiling: body fluid identification using multiplex real time-polymerase chain reaction (q-PCR)
WO2006081426A2 (en) * 2005-01-28 2006-08-03 Applera Corporation Compositions and methods for terminating a sequencing reaction at a specific location in a target dna template
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CN106715768B (zh) * 2014-07-30 2020-06-16 哈佛学院院长及董事 用于测定核酸的系统和方法
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WO2018218150A1 (en) 2017-05-26 2018-11-29 President And Fellows Of Harvard College Systems and methods for high-throughput image-based screening
KR101899371B1 (ko) * 2017-07-25 2018-10-29 (주)엔바이오텍 핵산 복합체 페어, 핵산 복합체 페어를 포함하는 pcr용 키트, 및 핵산 복합체 페어를 이용한 타겟 검출 방법
KR102262260B1 (ko) * 2018-02-08 2021-06-09 주식회사 시선테라퓨틱스 엔도좀 탈출능을 갖는 펩티드 핵산 복합체 및 이의 용도
KR20210104076A (ko) 2018-12-13 2021-08-24 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 Merfish 및 다른 적용을 위한 증폭 방법 및 시스템
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Also Published As

Publication number Publication date
JP4644370B2 (ja) 2011-03-02
JP2009017882A (ja) 2009-01-29
US7057025B2 (en) 2006-06-06
AU2850400A (en) 2000-08-01
WO2000041549A2 (en) 2000-07-20
DE60028534T2 (de) 2007-06-06
JP2005160489A (ja) 2005-06-23
DE60028534D1 (de) 2006-07-20
CA2360543C (en) 2009-03-31
EP1141387A2 (de) 2001-10-10
US20070026429A1 (en) 2007-02-01
WO2000041549A3 (en) 2000-11-30
US8067165B2 (en) 2011-11-29
US20100291557A1 (en) 2010-11-18
EP1141387B1 (de) 2006-06-07
US20060035217A1 (en) 2006-02-16
US6432642B1 (en) 2002-08-13
JP2002534100A (ja) 2002-10-15
AU771650B2 (en) 2004-04-01
CA2360543A1 (en) 2000-07-20

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