DE60017955T2 - Verfahren und zusammensetzungen zur peptidsynthese - Google Patents
Verfahren und zusammensetzungen zur peptidsynthese Download PDFInfo
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- DE60017955T2 DE60017955T2 DE60017955T DE60017955T DE60017955T2 DE 60017955 T2 DE60017955 T2 DE 60017955T2 DE 60017955 T DE60017955 T DE 60017955T DE 60017955 T DE60017955 T DE 60017955T DE 60017955 T2 DE60017955 T2 DE 60017955T2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US349205 | 1989-05-09 | ||
| US09/349,205 US6469136B1 (en) | 1999-07-07 | 1999-07-07 | Methods and composition for peptide synthesis |
| PCT/US2000/035725 WO2001034635A2 (en) | 1999-07-07 | 2000-07-05 | Methods and compositions for peptide synthesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60017955D1 DE60017955D1 (de) | 2005-03-10 |
| DE60017955T2 true DE60017955T2 (de) | 2006-01-12 |
Family
ID=23371340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60017955T Expired - Fee Related DE60017955T2 (de) | 1999-07-07 | 2000-07-05 | Verfahren und zusammensetzungen zur peptidsynthese |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US6469136B1 (https=) |
| EP (1) | EP1372686B1 (https=) |
| JP (1) | JP2003530311A (https=) |
| KR (1) | KR100631874B1 (https=) |
| CN (1) | CN1267449C (https=) |
| AR (1) | AR024686A1 (https=) |
| AT (1) | ATE288278T1 (https=) |
| AU (1) | AU4133701A (https=) |
| BR (1) | BR0012249A (https=) |
| CA (1) | CA2378086A1 (https=) |
| DE (1) | DE60017955T2 (https=) |
| DK (1) | DK1372686T3 (https=) |
| ES (1) | ES2236043T3 (https=) |
| MX (1) | MXPA02000021A (https=) |
| PT (1) | PT1372686E (https=) |
| TW (1) | TWI237640B (https=) |
| WO (1) | WO2001034635A2 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6656906B1 (en) * | 1998-05-20 | 2003-12-02 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
| SK782002A3 (en) * | 1999-07-21 | 2003-08-05 | Lexigen Pharm Corp | FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
| IL166037A0 (en) * | 2002-07-24 | 2006-01-15 | Hoffmann La Roche | Pegylated t1249 polypeptide |
| US20040158037A1 (en) * | 2003-02-12 | 2004-08-12 | Bohling James Charles | Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and biologically active substances and therapeutics produced therewith |
| AU2004200485A1 (en) * | 2003-02-25 | 2004-09-09 | Rohm And Haas Company | Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto |
| PT1624891E (pt) | 2003-05-06 | 2010-01-05 | Syntonix Pharmaceuticals Inc | Proteínas quiméricas de factor de coagulação-fc destinadas ao tratamento da hemofilia |
| US7348004B2 (en) | 2003-05-06 | 2008-03-25 | Syntonix Pharmaceuticals, Inc. | Immunoglobulin chimeric monomer-dimer hybrids |
| TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
| EP1701971A2 (en) * | 2003-12-31 | 2006-09-20 | F.Hoffmann-La Roche Ag | Peptide synthesis using decanting filter |
| ATE410437T1 (de) * | 2003-12-31 | 2008-10-15 | Hoffmann La Roche | Verfahren und systeme zur rückgewinnung von peptiden |
| EP1701976A2 (en) * | 2003-12-31 | 2006-09-20 | F.Hoffmann-La Roche Ag | Peptide synthesis and deprotection with co-solvent |
| EP1701970A2 (en) * | 2003-12-31 | 2006-09-20 | F.Hoffmann-La Roche Ag | Methods for recovering cleaved peptide from a support |
| ES2295961T3 (es) * | 2003-12-31 | 2008-04-16 | F. Hoffmann-La Roche Ag | Proceso para la sintesis peptidica utilizacndo una cantidad reducida de agente de desproteccion. |
| JP4805911B2 (ja) * | 2004-03-15 | 2011-11-02 | ネクター セラピューティクス | Ｈｉｖ侵入阻害剤のポリマー系組成物及び複合体 |
| JP4886702B2 (ja) * | 2004-12-30 | 2012-02-29 | エフ．ホフマン−ラ ロシュ アーゲー | ペプチド中間体断片を使用するペプチドｔ−２０の合成 |
| WO2006069697A1 (en) * | 2004-12-30 | 2006-07-06 | F. Hoffmann-La Roche Ag | Colorimetrically assessing peptide characteristics |
| WO2006069779A1 (en) * | 2004-12-30 | 2006-07-06 | F. Hoffmann-La Roche Ag | Preparing of peptides with excellent solubility |
| ES2329270T3 (es) * | 2004-12-30 | 2009-11-24 | F. Hoffmann-La Roche Ag | Sintesis del peptido t-1249 utilizando fragmentos intermediarios del ipeptido. |
| WO2006105199A2 (en) * | 2005-03-30 | 2006-10-05 | Trimeris, Inc. | Compositions and methods for synthesis of peptide and related conjugate |
| TW200745163A (en) * | 2006-02-17 | 2007-12-16 | Syntonix Pharmaceuticals Inc | Peptides that block the binding of IgG to FcRn |
| US8022181B2 (en) | 2006-05-03 | 2011-09-20 | Mallinckrodt Llc | Composition and method for the release of protected peptides from a resin |
| CN101195653B (zh) * | 2006-12-08 | 2010-05-12 | 吉尔生化（上海）有限公司 | 亮丙瑞林的固液合成法 |
| MX2010001363A (es) * | 2007-08-09 | 2010-03-09 | Syntonix Pharmaceuticals Inc | Peptidos inmunomoduladores. |
| KR20100080812A (ko) * | 2007-09-25 | 2010-07-12 | 트라이머리스, 인코퍼레이티드 | 치료용 항-ｈｉｖ 펩티드의 합성 방법 |
| JP5473925B2 (ja) * | 2007-10-27 | 2014-04-16 | コーデン ファーマ コロラド インコーポレイテッド | 固相および溶液相の組み合わせ技法を使用するインスリン分泌性ペプチドの合成 |
| BRPI0820765A2 (pt) * | 2007-12-11 | 2015-06-16 | Hoffmann La Roche | Métodos para a produção de um peptídeo insulinotrópico e peptídeos |
| WO2010014909A1 (en) * | 2008-08-01 | 2010-02-04 | Syntonix Pharmaceuticals, Inc. | Immunomodulatory peptides |
| SG10201505217WA (en) | 2010-07-09 | 2015-08-28 | Biogen Hemophilia Inc | Chimeric clotting factors |
| CN102268065A (zh) * | 2011-06-23 | 2011-12-07 | 成都圣诺科技发展有限公司 | 氨基保护丝氨酸寡肽及其制备方法和用途 |
| CN102603869B (zh) * | 2012-03-27 | 2013-03-27 | 西安华澳丽康生物工程有限公司 | 六胜肽的合成方法 |
| AR095527A1 (es) | 2013-03-15 | 2015-10-21 | Biogen Idec Inc | Formulaciones de polipéptido fc-factor ix |
| WO2014147129A1 (en) | 2013-03-21 | 2014-09-25 | Sanofi-Aventis Deutschland Gmbh | Synthesis of cyclic imide containing peptide products |
| CN105189465B (zh) | 2013-03-21 | 2019-02-26 | 赛诺菲-安万特德国有限公司 | 合成含有乙内酰脲的肽产物 |
| CN108572171A (zh) * | 2017-03-10 | 2018-09-25 | 江苏金斯瑞生物科技有限公司 | 一种检测哌啶残留的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4010560B2 (ja) * | 1992-07-20 | 2007-11-21 | ドューク ユニバーシティー | Ｈｉｖ複製を阻害する化合物 |
| JP3401005B2 (ja) | 1992-12-11 | 2003-04-28 | ユニバーシティ オブ フロリダ | 有害生物の防除のための材料および方法 |
| US5464933A (en) * | 1993-06-07 | 1995-11-07 | Duke University | Synthetic peptide inhibitors of HIV transmission |
| EP0708659A4 (en) | 1993-06-07 | 2000-08-23 | Genentech Inc | HIV ENVELOPE POLYPEPTIDES |
| US6479055B1 (en) | 1993-06-07 | 2002-11-12 | Trimeris, Inc. | Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission |
| CA2324348C (en) * | 1998-03-23 | 2006-03-14 | Trimeris, Inc. | Methods and compositions for peptide synthesis |
| US6258782B1 (en) * | 1998-05-20 | 2001-07-10 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
| US6217666B1 (en) | 1998-08-31 | 2001-04-17 | Danieli Technology, Inc. | Countercurrent reduction of oxides on moving metal |
-
1999
- 1999-07-07 US US09/349,205 patent/US6469136B1/en not_active Expired - Fee Related
-
2000
- 2000-07-05 KR KR1020027000199A patent/KR100631874B1/ko not_active Expired - Fee Related
- 2000-07-05 PT PT00992116T patent/PT1372686E/pt unknown
- 2000-07-05 MX MXPA02000021A patent/MXPA02000021A/es active IP Right Grant
- 2000-07-05 DE DE60017955T patent/DE60017955T2/de not_active Expired - Fee Related
- 2000-07-05 JP JP2001537346A patent/JP2003530311A/ja not_active Ceased
- 2000-07-05 DK DK00992116T patent/DK1372686T3/da active
- 2000-07-05 CN CNB008125309A patent/CN1267449C/zh not_active Expired - Fee Related
- 2000-07-05 CA CA002378086A patent/CA2378086A1/en not_active Abandoned
- 2000-07-05 EP EP00992116A patent/EP1372686B1/en not_active Expired - Lifetime
- 2000-07-05 AU AU41337/01A patent/AU4133701A/en not_active Abandoned
- 2000-07-05 ES ES00992116T patent/ES2236043T3/es not_active Expired - Lifetime
- 2000-07-05 WO PCT/US2000/035725 patent/WO2001034635A2/en not_active Ceased
- 2000-07-05 BR BR0012249-1A patent/BR0012249A/pt not_active IP Right Cessation
- 2000-07-05 AT AT00992116T patent/ATE288278T1/de not_active IP Right Cessation
- 2000-07-07 AR ARP000103508A patent/AR024686A1/es active IP Right Grant
- 2000-08-05 TW TW089113543A patent/TWI237640B/zh active
-
2002
- 2002-03-29 US US10/109,748 patent/US6767993B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001034635A9 (en) | 2002-08-01 |
| CN1450906A (zh) | 2003-10-22 |
| EP1372686A2 (en) | 2004-01-02 |
| TWI237640B (en) | 2005-08-11 |
| JP2003530311A (ja) | 2003-10-14 |
| EP1372686A4 (en) | 2004-01-02 |
| ES2236043T3 (es) | 2005-07-16 |
| US6469136B1 (en) | 2002-10-22 |
| PT1372686E (pt) | 2005-05-31 |
| CN1267449C (zh) | 2006-08-02 |
| DE60017955D1 (de) | 2005-03-10 |
| AU4133701A (en) | 2001-06-06 |
| CA2378086A1 (en) | 2001-05-17 |
| EP1372686B1 (en) | 2005-02-02 |
| ATE288278T1 (de) | 2005-02-15 |
| WO2001034635A3 (en) | 2003-10-16 |
| US20030125516A1 (en) | 2003-07-03 |
| MXPA02000021A (es) | 2002-07-02 |
| US6767993B2 (en) | 2004-07-27 |
| KR100631874B1 (ko) | 2006-10-09 |
| AR024686A1 (es) | 2002-10-23 |
| DK1372686T3 (da) | 2005-05-30 |
| KR20020038676A (ko) | 2002-05-23 |
| BR0012249A (pt) | 2003-11-11 |
| WO2001034635A2 (en) | 2001-05-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |