DK1372686T3 - Fremgangsmåder og sammensætninger til peptidsyntese - Google Patents

Fremgangsmåder og sammensætninger til peptidsyntese

Info

Publication number
DK1372686T3
DK1372686T3 DK00992116T DK00992116T DK1372686T3 DK 1372686 T3 DK1372686 T3 DK 1372686T3 DK 00992116 T DK00992116 T DK 00992116T DK 00992116 T DK00992116 T DK 00992116T DK 1372686 T3 DK1372686 T3 DK 1372686T3
Authority
DK
Denmark
Prior art keywords
compositions
methods
peptide synthesis
peptide
synthesis
Prior art date
Application number
DK00992116T
Other languages
Danish (da)
English (en)
Inventor
Brian Bray
Myung-Chol Kang
Marc Andersen
Paul E Friedrich
Original Assignee
Trimeris Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trimeris Inc filed Critical Trimeris Inc
Application granted granted Critical
Publication of DK1372686T3 publication Critical patent/DK1372686T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK00992116T 1999-07-07 2000-07-05 Fremgangsmåder og sammensætninger til peptidsyntese DK1372686T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/349,205 US6469136B1 (en) 1999-07-07 1999-07-07 Methods and composition for peptide synthesis
PCT/US2000/035725 WO2001034635A2 (en) 1999-07-07 2000-07-05 Methods and compositions for peptide synthesis

Publications (1)

Publication Number Publication Date
DK1372686T3 true DK1372686T3 (da) 2005-05-30

Family

ID=23371340

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00992116T DK1372686T3 (da) 1999-07-07 2000-07-05 Fremgangsmåder og sammensætninger til peptidsyntese

Country Status (17)

Country Link
US (2) US6469136B1 (https=)
EP (1) EP1372686B1 (https=)
JP (1) JP2003530311A (https=)
KR (1) KR100631874B1 (https=)
CN (1) CN1267449C (https=)
AR (1) AR024686A1 (https=)
AT (1) ATE288278T1 (https=)
AU (1) AU4133701A (https=)
BR (1) BR0012249A (https=)
CA (1) CA2378086A1 (https=)
DE (1) DE60017955T2 (https=)
DK (1) DK1372686T3 (https=)
ES (1) ES2236043T3 (https=)
MX (1) MXPA02000021A (https=)
PT (1) PT1372686E (https=)
TW (1) TWI237640B (https=)
WO (1) WO2001034635A2 (https=)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6656906B1 (en) * 1998-05-20 2003-12-02 Trimeris, Inc. Hybrid polypeptides with enhanced pharmacokinetic properties
SK782002A3 (en) * 1999-07-21 2003-08-05 Lexigen Pharm Corp FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
WO2004013165A1 (en) * 2002-07-24 2004-02-12 F. Hoffmann-La Roche Ag Pegylated t1249 polypeptide
US20040158037A1 (en) * 2003-02-12 2004-08-12 Bohling James Charles Amino acid loaded trityl alcohol resins, method of production of amino acid loaded trityl alcohol resins and biologically active substances and therapeutics produced therewith
AU2004200485A1 (en) * 2003-02-25 2004-09-09 Rohm And Haas Company Method of manufacturing T-20 and T-1249 peptides at commercial scale, and T-20 and T-1249 compositions related thereto
PL2298347T3 (pl) * 2003-05-06 2016-03-31 Bioverativ Therapeutics Inc Białka chimeryczne czynnika krzepnięcia do leczenia zaburzenia hemostazy
TWI353991B (en) * 2003-05-06 2011-12-11 Syntonix Pharmaceuticals Inc Immunoglobulin chimeric monomer-dimer hybrids
US7348004B2 (en) 2003-05-06 2008-03-25 Syntonix Pharmaceuticals, Inc. Immunoglobulin chimeric monomer-dimer hybrids
WO2005063792A2 (en) * 2003-12-31 2005-07-14 F. Hoffmann-La Roche Ag Methods for recovering cleaved peptide from a support
EP1701976A2 (en) * 2003-12-31 2006-09-20 F.Hoffmann-La Roche Ag Peptide synthesis and deprotection with co-solvent
WO2005063800A2 (en) * 2003-12-31 2005-07-14 F. Hoffmann-La Roche Ag Peptide synthesis using decanting filter
ATE376556T1 (de) * 2003-12-31 2007-11-15 Hoffmann La Roche Verfahren zur peptidsynthese unter verwendung einer reduzierten menge an entschützungsmittel
ATE410437T1 (de) * 2003-12-31 2008-10-15 Hoffmann La Roche Verfahren und systeme zur rückgewinnung von peptiden
KR101276422B1 (ko) * 2004-03-15 2013-06-19 넥타르 테라퓨틱스 Ｈｉｖ 유입 억제제의 중합체-기재 조성물 및 콘쥬게이트
ES2329270T3 (es) * 2004-12-30 2009-11-24 F. Hoffmann-La Roche Ag Sintesis del peptido t-1249 utilizando fragmentos intermediarios del ipeptido.
JP4886702B2 (ja) * 2004-12-30 2012-02-29 エフ．ホフマン−ラ ロシュ アーゲー ペプチド中間体断片を使用するペプチドｔ−２０の合成
WO2006069779A1 (en) * 2004-12-30 2006-07-06 F. Hoffmann-La Roche Ag Preparing of peptides with excellent solubility
WO2006069697A1 (en) * 2004-12-30 2006-07-06 F. Hoffmann-La Roche Ag Colorimetrically assessing peptide characteristics
WO2006105199A2 (en) * 2005-03-30 2006-10-05 Trimeris, Inc. Compositions and methods for synthesis of peptide and related conjugate
TW200745163A (en) 2006-02-17 2007-12-16 Syntonix Pharmaceuticals Inc Peptides that block the binding of IgG to FcRn
CA2651070A1 (en) 2006-05-03 2007-11-15 Mallinckrodt Inc. Composition and method for the release of protected peptides from a resin
CN101195653B (zh) * 2006-12-08 2010-05-12 吉尔生化（上海）有限公司 亮丙瑞林的固液合成法
TW200911289A (en) * 2007-08-09 2009-03-16 Syntonix Pharmaceuticals Inc Immunomodulatory peptides
CN101874038A (zh) * 2007-09-25 2010-10-27 特里梅里斯公司 治疗性抗-hiv肽的合成方法
CN101835794A (zh) * 2007-10-27 2010-09-15 霍夫曼-拉罗奇有限公司 使用固相和溶液相组合技术的促胰岛素肽合成法
EP2222695A2 (en) * 2007-12-11 2010-09-01 F. Hoffmann-La Roche AG Insulinotropic peptide synthesis using solid and solution phase combination techniques
WO2010014909A1 (en) * 2008-08-01 2010-02-04 Syntonix Pharmaceuticals, Inc. Immunomodulatory peptides
TW201217527A (en) 2010-07-09 2012-05-01 Biogen Idec Hemophilia Inc Processable single chain molecules and polypeptides made using same
CN102268065A (zh) * 2011-06-23 2011-12-07 成都圣诺科技发展有限公司 氨基保护丝氨酸寡肽及其制备方法和用途
CN102603869B (zh) * 2012-03-27 2013-03-27 西安华澳丽康生物工程有限公司 六胜肽的合成方法
WO2014144549A1 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Factor ix polypeptide formulations
US10450343B2 (en) 2013-03-21 2019-10-22 Sanofi-Aventis Deutschland Gmbh Synthesis of cyclic imide containing peptide products
CA2907454C (en) 2013-03-21 2021-05-04 Sanofi-Aventis Deutschland Gmbh Synthesis of hydantoin containing peptide products
CN108572171A (zh) * 2017-03-10 2018-09-25 江苏金斯瑞生物科技有限公司 一种检测哌啶残留的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100358209B1 (ko) 1992-07-20 2003-01-24 듀크 유니버시티 Hiv복제를저해하는조성물
JP3401005B2 (ja) 1992-12-11 2003-04-28 ユニバーシティ オブ フロリダ 有害生物の防除のための材料および方法
WO1994028929A1 (en) 1993-06-07 1994-12-22 Genentech, Inc. Hiv envelope polypeptides
US6479055B1 (en) 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
US5464933A (en) 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
WO1999048513A1 (en) * 1998-03-23 1999-09-30 Trimeris, Inc. Methods and compositions for peptide synthesis
US6258782B1 (en) * 1998-05-20 2001-07-10 Trimeris, Inc. Hybrid polypeptides with enhanced pharmacokinetic properties
US6217666B1 (en) 1998-08-31 2001-04-17 Danieli Technology, Inc. Countercurrent reduction of oxides on moving metal

Also Published As

Publication number Publication date
AU4133701A (en) 2001-06-06
ES2236043T3 (es) 2005-07-16
CN1267449C (zh) 2006-08-02
EP1372686B1 (en) 2005-02-02
CN1450906A (zh) 2003-10-22
JP2003530311A (ja) 2003-10-14
TWI237640B (en) 2005-08-11
EP1372686A4 (en) 2004-01-02
US6767993B2 (en) 2004-07-27
KR100631874B1 (ko) 2006-10-09
KR20020038676A (ko) 2002-05-23
US6469136B1 (en) 2002-10-22
PT1372686E (pt) 2005-05-31
WO2001034635A3 (en) 2003-10-16
DE60017955T2 (de) 2006-01-12
BR0012249A (pt) 2003-11-11
WO2001034635A9 (en) 2002-08-01
US20030125516A1 (en) 2003-07-03
CA2378086A1 (en) 2001-05-17
WO2001034635A2 (en) 2001-05-17
DE60017955D1 (de) 2005-03-10
MXPA02000021A (es) 2002-07-02
AR024686A1 (es) 2002-10-23
EP1372686A2 (en) 2004-01-02
ATE288278T1 (de) 2005-02-15

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