DE60013764D1 - Behandlung und vorbeugung von durch reaktive sauerstoffmetabolite verursachten zellschäden - Google Patents
Behandlung und vorbeugung von durch reaktive sauerstoffmetabolite verursachten zellschädenInfo
- Publication number
- DE60013764D1 DE60013764D1 DE60013764T DE60013764T DE60013764D1 DE 60013764 D1 DE60013764 D1 DE 60013764D1 DE 60013764 T DE60013764 T DE 60013764T DE 60013764 T DE60013764 T DE 60013764T DE 60013764 D1 DE60013764 D1 DE 60013764D1
- Authority
- DE
- Germany
- Prior art keywords
- reactive oxygen
- damage caused
- prevention
- treatment
- roms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/227,455 US6242473B1 (en) | 1999-01-08 | 1999-01-08 | Treatment and prevention of reactive oxygen metabolite-mediated cellular damage |
US227455 | 1999-01-08 | ||
PCT/US2000/000314 WO2000040241A2 (en) | 1999-01-08 | 2000-01-07 | Treatment and prevention of reactive oxygen metabolite-mediated cellular damage |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60013764D1 true DE60013764D1 (de) | 2004-10-21 |
DE60013764T2 DE60013764T2 (de) | 2005-09-29 |
Family
ID=22853182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60013764T Expired - Fee Related DE60013764T2 (de) | 1999-01-08 | 2000-01-07 | Behandlung und vorbeugung von durch reaktive sauerstoffmetabolite verursachten zellschäden |
Country Status (16)
Country | Link |
---|---|
US (6) | US6242473B1 (de) |
EP (2) | EP1410798A3 (de) |
JP (1) | JP2002534384A (de) |
KR (1) | KR20010101416A (de) |
CN (1) | CN1203851C (de) |
AT (1) | ATE275954T1 (de) |
AU (1) | AU768526B2 (de) |
CA (1) | CA2358851A1 (de) |
DE (1) | DE60013764T2 (de) |
ES (1) | ES2228453T3 (de) |
HK (1) | HK1040923B (de) |
IL (1) | IL143970A0 (de) |
PT (1) | PT1140077E (de) |
TW (1) | TWI248816B (de) |
WO (1) | WO2000040241A2 (de) |
ZA (1) | ZA200105165B (de) |
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US6270781B1 (en) * | 1999-01-08 | 2001-08-07 | Maxim Pharmaceuticals, Inc. | Method and compositions for topical treatment of damaged tissue using reactive oxygen metabolite production or release inhibitors |
US6242473B1 (en) * | 1999-01-08 | 2001-06-05 | Maxim Pharmaceuticals, Inc. | Treatment and prevention of reactive oxygen metabolite-mediated cellular damage |
US7341717B2 (en) * | 2001-04-13 | 2008-03-11 | Gpc Biotech Ag | Therapeutic targets for treatment of HCV infections, methods of treating HCV infections and compounds useful therefor |
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KR20040058192A (ko) * | 2001-10-19 | 2004-07-03 | 맥심 파마수티컬즈 인크. | 간 질환 치료용으로서의 히스타민 용도 |
KR20050043763A (ko) * | 2001-11-06 | 2005-05-11 | 맥심 파마수티컬즈 인크. | 감염 질환의 치료용 조성물 |
JP2006512279A (ja) * | 2002-03-29 | 2006-04-13 | マキシム ファーマシューティカルス,インコーポレイテッド | 眼内損傷を治療および予防するためのrom生成および放出阻害剤の使用 |
US20040106896A1 (en) * | 2002-11-29 | 2004-06-03 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
CN1649641A (zh) * | 2002-05-08 | 2005-08-03 | 加利福尼亚大学董事会 | 形成非切除性心脏传导阻滞的系统和方法 |
CA2483105C (en) | 2002-05-13 | 2011-05-10 | Arexis Ab | Autoimmune conditions and nadph oxidase defects |
EP1380290A1 (de) * | 2002-07-09 | 2004-01-14 | Universitair Medisch Centrum Utrecht | Cross-Beta-Strukturweg und seine therapeutische Relevanz |
US20070003552A1 (en) * | 2002-07-09 | 2007-01-04 | Gebbink Martijn F B | Cross-beta structure comprising amyloid binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity and method for interfering with blood coagulation |
US20040057983A1 (en) | 2002-09-25 | 2004-03-25 | David Schmidt | Biomolecular wearable apparatus |
US7317950B2 (en) * | 2002-11-16 | 2008-01-08 | The Regents Of The University Of California | Cardiac stimulation system with delivery of conductive agent |
AU2003297294A1 (en) * | 2002-11-20 | 2004-06-15 | Board Of Regents, The University Of Texas System | Methods for inhibiting allergic inflammation and other responses initiated by pollens, molds, and other non-animal derived allergens |
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US20050171192A1 (en) * | 2003-12-11 | 2005-08-04 | Gehlsen Kurt R. | Use of histamine to treat bone disease |
TW200538181A (en) | 2004-05-18 | 2005-12-01 | Brni Neurosciences Inst | Treatment of depressive disorders |
EP1602926A1 (de) | 2004-06-04 | 2005-12-07 | University of Geneva | Neue Mittel und Verfahren zur Behandlung von Gehörverlust oder Tinnitus |
US20090202980A1 (en) * | 2005-03-21 | 2009-08-13 | Crossbeta Biosciences B.V. | Cross-Beta Structure Comprising Amyloid Binding Proteins and Methods for Detection of the Cross-Beta Structure, for Modulating Cross-Beta Structures Fibril Formation and for Modulating Cross-Beta Structure-Mediated Toxicity and Method for Interfering With Blood Coagulation |
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US8114832B2 (en) * | 2005-07-13 | 2012-02-14 | Crossbeta Biosciences B.V. | Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition |
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-
1999
- 1999-01-08 US US09/227,455 patent/US6242473B1/en not_active Expired - Fee Related
- 1999-08-26 TW TW088114611A patent/TWI248816B/zh active
-
2000
- 2000-01-07 PT PT00902340T patent/PT1140077E/pt unknown
- 2000-01-07 CA CA002358851A patent/CA2358851A1/en not_active Abandoned
- 2000-01-07 CN CNB008045828A patent/CN1203851C/zh not_active Expired - Fee Related
- 2000-01-07 EP EP03026944A patent/EP1410798A3/de not_active Withdrawn
- 2000-01-07 ES ES00902340T patent/ES2228453T3/es not_active Expired - Lifetime
- 2000-01-07 EP EP00902340A patent/EP1140077B1/de not_active Expired - Lifetime
- 2000-01-07 JP JP2000591998A patent/JP2002534384A/ja active Pending
- 2000-01-07 KR KR1020017008621A patent/KR20010101416A/ko not_active Application Discontinuation
- 2000-01-07 AT AT00902340T patent/ATE275954T1/de not_active IP Right Cessation
- 2000-01-07 DE DE60013764T patent/DE60013764T2/de not_active Expired - Fee Related
- 2000-01-07 AU AU24075/00A patent/AU768526B2/en not_active Ceased
- 2000-01-07 WO PCT/US2000/000314 patent/WO2000040241A2/en not_active Application Discontinuation
- 2000-01-07 IL IL14397000A patent/IL143970A0/xx unknown
- 2000-11-06 US US09/707,343 patent/US6462067B1/en not_active Expired - Fee Related
-
2001
- 2001-04-12 US US09/833,896 patent/US6407133B2/en not_active Expired - Fee Related
- 2001-06-22 ZA ZA200105165A patent/ZA200105165B/xx unknown
-
2002
- 2002-04-10 HK HK02102711.2A patent/HK1040923B/zh not_active IP Right Cessation
- 2002-06-11 US US10/171,018 patent/US6730692B2/en not_active Expired - Lifetime
- 2002-09-19 US US10/251,420 patent/US20030017145A1/en not_active Abandoned
-
2004
- 2004-04-07 US US10/819,594 patent/US20040191239A1/en not_active Abandoned
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WO2000040241A3 (en) | 2000-11-30 |
AU768526B2 (en) | 2003-12-18 |
US20010023256A1 (en) | 2001-09-20 |
AU2407500A (en) | 2000-07-24 |
CA2358851A1 (en) | 2000-07-13 |
PT1140077E (pt) | 2005-01-31 |
IL143970A0 (en) | 2002-04-21 |
US20040191239A1 (en) | 2004-09-30 |
CN1203851C (zh) | 2005-06-01 |
CN1342079A (zh) | 2002-03-27 |
US6462067B1 (en) | 2002-10-08 |
JP2002534384A (ja) | 2002-10-15 |
ZA200105165B (en) | 2002-06-12 |
US6242473B1 (en) | 2001-06-05 |
US20030017145A1 (en) | 2003-01-23 |
ATE275954T1 (de) | 2004-10-15 |
WO2000040241A2 (en) | 2000-07-13 |
US6407133B2 (en) | 2002-06-18 |
HK1040923B (zh) | 2005-04-01 |
DE60013764T2 (de) | 2005-09-29 |
HK1040923A1 (en) | 2002-06-28 |
ES2228453T3 (es) | 2005-04-16 |
KR20010101416A (ko) | 2001-11-14 |
EP1410798A3 (de) | 2004-10-13 |
EP1410798A2 (de) | 2004-04-21 |
US6730692B2 (en) | 2004-05-04 |
TWI248816B (en) | 2006-02-11 |
US20020150565A1 (en) | 2002-10-17 |
EP1140077B1 (de) | 2004-09-15 |
EP1140077A2 (de) | 2001-10-10 |
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