IT1230140B - Derivati della serina, loro processo di preparazione e impiego in terapia umana - Google Patents

Derivati della serina, loro processo di preparazione e impiego in terapia umana

Info

Publication number
IT1230140B
IT1230140B IT8920357A IT2035789A IT1230140B IT 1230140 B IT1230140 B IT 1230140B IT 8920357 A IT8920357 A IT 8920357A IT 2035789 A IT2035789 A IT 2035789A IT 1230140 B IT1230140 B IT 1230140B
Authority
IT
Italy
Prior art keywords
derivatives
serina
preparation
human therapy
therapy
Prior art date
Application number
IT8920357A
Other languages
English (en)
Other versions
IT8920357A0 (it
Inventor
Francesco Della Valle
Aurelio Romeo
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Priority to IT8920357A priority Critical patent/IT1230140B/it
Publication of IT8920357A0 publication Critical patent/IT8920357A0/it
Priority to DE69016085T priority patent/DE69016085T2/de
Priority to ES90108222T priority patent/ES2070202T3/es
Priority to EP90108222A priority patent/EP0396080B1/en
Priority to AT90108222T priority patent/ATE117307T1/de
Priority to JP2118501A priority patent/JPH0735389B2/ja
Application granted granted Critical
Publication of IT1230140B publication Critical patent/IT1230140B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT8920357A 1989-05-03 1989-05-03 Derivati della serina, loro processo di preparazione e impiego in terapia umana IT1230140B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT8920357A IT1230140B (it) 1989-05-03 1989-05-03 Derivati della serina, loro processo di preparazione e impiego in terapia umana
DE69016085T DE69016085T2 (de) 1989-05-03 1990-04-30 Serinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung in der Humantherapie.
ES90108222T ES2070202T3 (es) 1989-05-03 1990-04-30 Nuevos derivados de serina, procedimiento para su preparacion y su uso en terapia humana.
EP90108222A EP0396080B1 (en) 1989-05-03 1990-04-30 New serine derivatives, process for their preparation and their use in human therapy
AT90108222T ATE117307T1 (de) 1989-05-03 1990-04-30 Serinderivate, verfahren zu ihrer herstellung und ihre verwendung in der humantherapie.
JP2118501A JPH0735389B2 (ja) 1989-05-03 1990-05-07 新規セリン誘導体、その製造方法およびヒト治療への用途

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920357A IT1230140B (it) 1989-05-03 1989-05-03 Derivati della serina, loro processo di preparazione e impiego in terapia umana

Publications (2)

Publication Number Publication Date
IT8920357A0 IT8920357A0 (it) 1989-05-03
IT1230140B true IT1230140B (it) 1991-10-14

Family

ID=11166005

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8920357A IT1230140B (it) 1989-05-03 1989-05-03 Derivati della serina, loro processo di preparazione e impiego in terapia umana

Country Status (6)

Country Link
EP (1) EP0396080B1 (it)
JP (1) JPH0735389B2 (it)
AT (1) ATE117307T1 (it)
DE (1) DE69016085T2 (it)
ES (1) ES2070202T3 (it)
IT (1) IT1230140B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1249063B (it) * 1991-05-28 1995-02-11 Fidia Spa Impiego di derivati fosfolipidici per la preparazione di composizioni farmaceutiche aventi attivita' immunosoppressiva
JP3053537B2 (ja) * 1994-11-08 2000-06-19 株式会社ヤクルト本社 脳機能改善剤
US6242473B1 (en) * 1999-01-08 2001-06-05 Maxim Pharmaceuticals, Inc. Treatment and prevention of reactive oxygen metabolite-mediated cellular damage
JP5140824B2 (ja) * 2006-04-19 2013-02-13 国立大学法人 東京大学 リゾホスファチジルスレオニンおよびその誘導体
JP2010184867A (ja) * 2009-02-10 2010-08-26 Univ Of Tokyo リゾホスファチジルスレオニン誘導体
JP6153019B2 (ja) * 2013-01-31 2017-06-28 国立大学法人 東京大学 リゾホスファチジルセリン受容体機能調節活性を有する化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1123142B (it) * 1979-09-14 1986-04-30 Lpb Ist Farm Uso di glicerilfosforil derivati nella terapia di dislipemie ed epatiti,e composizioni farmaceutiche relative
DE3572491D1 (en) * 1984-07-25 1989-09-28 Ciba Geigy Ag Phosphatidyl compounds, process for their preparation and their use
IT1213034B (it) * 1986-02-12 1989-12-07 Istituto Chemioterapico Di Lod Composizioni farmaceutiche per la terapia di cerebropatie su base organica e funzionale.

Also Published As

Publication number Publication date
IT8920357A0 (it) 1989-05-03
DE69016085T2 (de) 1995-05-18
EP0396080A3 (en) 1991-04-10
ATE117307T1 (de) 1995-02-15
ES2070202T3 (es) 1995-06-01
JPH0735389B2 (ja) 1995-04-19
JPH02306982A (ja) 1990-12-20
DE69016085D1 (de) 1995-03-02
EP0396080A2 (en) 1990-11-07
EP0396080B1 (en) 1995-01-18

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950525