DE59409312D1 - Imidazopyridine und ihre anwendung zur behandlung von magen-darm krankheiten - Google Patents

Imidazopyridine und ihre anwendung zur behandlung von magen-darm krankheiten

Info

Publication number
DE59409312D1
DE59409312D1 DE59409312T DE59409312T DE59409312D1 DE 59409312 D1 DE59409312 D1 DE 59409312D1 DE 59409312 T DE59409312 T DE 59409312T DE 59409312 T DE59409312 T DE 59409312T DE 59409312 D1 DE59409312 D1 DE 59409312D1
Authority
DE
Germany
Prior art keywords
stomeline
imidazopyridine
diseases
treatment
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE59409312T
Other languages
German (de)
English (en)
Inventor
Joerg Senn-Bilfinger
Gerhard Grundler
Georg Rainer
Stefan Postius
Richard Riedel
Wolfgang-Alexander Simon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Application granted granted Critical
Publication of DE59409312D1 publication Critical patent/DE59409312D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE59409312T 1993-02-15 1994-02-07 Imidazopyridine und ihre anwendung zur behandlung von magen-darm krankheiten Expired - Fee Related DE59409312D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH45393 1993-02-15
CH194593 1993-06-29
PCT/EP1994/000335 WO1994018199A1 (de) 1993-02-15 1994-02-07 Imidazopyridine und ihre anwendung zur behandlung von magen-darm krankheiten

Publications (1)

Publication Number Publication Date
DE59409312D1 true DE59409312D1 (de) 2000-05-31

Family

ID=25684624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE59409312T Expired - Fee Related DE59409312D1 (de) 1993-02-15 1994-02-07 Imidazopyridine und ihre anwendung zur behandlung von magen-darm krankheiten

Country Status (29)

Country Link
US (1) US5665730A (enExample)
EP (1) EP0683780B1 (enExample)
JP (1) JP3447292B2 (enExample)
KR (1) KR100297057B1 (enExample)
CN (1) CN1052005C (enExample)
AT (1) ATE192151T1 (enExample)
AU (1) AU678434B2 (enExample)
BG (1) BG62773B1 (enExample)
CA (1) CA2156078C (enExample)
CZ (1) CZ287313B6 (enExample)
DE (1) DE59409312D1 (enExample)
DK (1) DK0683780T3 (enExample)
ES (1) ES2148317T3 (enExample)
FI (1) FI109537B (enExample)
GR (1) GR3033846T3 (enExample)
HU (1) HU219395B (enExample)
IL (1) IL108520A (enExample)
MY (1) MY111201A (enExample)
NO (1) NO304889B1 (enExample)
NZ (1) NZ261579A (enExample)
PL (1) PL175932B1 (enExample)
PT (1) PT683780E (enExample)
RO (1) RO117917B1 (enExample)
RU (1) RU2136682C1 (enExample)
SG (1) SG55184A1 (enExample)
SK (1) SK280822B6 (enExample)
TW (1) TW293008B (enExample)
UA (1) UA43841C2 (enExample)
WO (1) WO1994018199A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2191979A1 (en) * 1994-06-20 1995-12-28 Muneo Takatani Condensed imidazole compounds, their production and use
CN1046726C (zh) * 1994-07-28 1999-11-24 比克·古尔顿·劳姆贝尔格化学公司 咪唑并吡啶-吡咯烷酮、其制法和药用
JPH10505331A (ja) * 1994-07-28 1998-05-26 ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンジルイミダゾピリジン
AU3343295A (en) * 1994-08-12 1996-03-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazopyridine salt
US6132768A (en) * 1995-07-05 2000-10-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for reversible proton pump inhibitors
JP2949474B2 (ja) * 1995-08-28 1999-09-13 隆久 古田 ペプシノーゲンi/ii比の変化率を基礎としたヘリコバクター・ピロリ除菌判定方法
EP0882048B1 (de) * 1996-01-26 2005-05-04 ALTANA Pharma AG 3-alkylimidazopyridine
DE19602855A1 (de) * 1996-01-26 1997-07-31 Byk Gulden Lomberg Chem Fab Neue 3-Methylimidazopyridine
AU1545297A (en) * 1996-01-26 1997-08-20 Byk Gulden Imidazopyridine halides
BR9807883A (pt) 1997-03-24 2000-02-22 Byk Gulden Lomberg Chem Fab Compostos de tetraidropirido
HUP0001555A3 (en) * 1997-10-30 2001-01-29 Altana Pharma Ag Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
SE9802794D0 (sv) 1998-08-21 1998-08-21 Astra Ab New compounds
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
AU3966600A (en) * 1999-04-17 2000-11-02 Byk Gulden Lomberg Chemische Fabrik Gmbh Haloalkoxy imidazonaphthyridines
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6369087B1 (en) * 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
DE10019714A1 (de) * 2000-04-20 2002-01-10 Gruenenthal Gmbh Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) * 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
DE10145457A1 (de) * 2001-09-14 2003-04-03 Basf Ag Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
AU2003254282A1 (en) * 2002-08-01 2004-02-23 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
EA009985B1 (ru) 2003-03-10 2008-04-28 Никомед Гмбх Новый способ получения рофлумиласта
RU2241710C1 (ru) * 2003-04-24 2004-12-10 Ярославский государственный технический университет Способ получения замещенных пиридо[1,2-а][1,3]бензимидазолов
EP1682133A1 (en) 2003-11-03 2006-07-26 AstraZeneca AB Imidazo 1,2-a pyridine derivatives for the treatment of silent gastro-esophageal reflux
AR049168A1 (es) * 2004-05-18 2006-07-05 Altana Pharma Ag Derivados de benzimidazol
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
WO1986003720A1 (fr) * 1984-12-14 1986-07-03 Moebius Ulrich Fixation pour skis
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
US4831041A (en) * 1986-11-26 1989-05-16 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound

Also Published As

Publication number Publication date
SK280822B6 (sk) 2000-08-14
NZ261579A (en) 1997-03-24
DK0683780T3 (da) 2000-09-25
SK99795A3 (en) 1995-12-06
AU678434B2 (en) 1997-05-29
FI109537B (fi) 2002-08-30
RO117917B1 (ro) 2002-09-30
SG55184A1 (en) 1998-12-21
HU219395B (hu) 2001-04-28
FI953838L (fi) 1995-09-06
CZ208895A3 (en) 1995-12-13
CN1119863A (zh) 1996-04-03
WO1994018199A1 (de) 1994-08-18
IL108520A (en) 1997-09-30
EP0683780B1 (de) 2000-04-26
ES2148317T3 (es) 2000-10-16
KR100297057B1 (ko) 2001-10-24
ATE192151T1 (de) 2000-05-15
KR960701051A (ko) 1996-02-24
GR3033846T3 (en) 2000-10-31
BG99855A (bg) 1996-04-30
UA43841C2 (uk) 2002-01-15
NO953187D0 (no) 1995-08-14
CA2156078C (en) 2005-02-01
US5665730A (en) 1997-09-09
PT683780E (pt) 2000-10-31
CN1052005C (zh) 2000-05-03
BG62773B1 (bg) 2000-07-31
PL175932B1 (pl) 1999-03-31
NO304889B1 (no) 1999-03-01
JPH08506333A (ja) 1996-07-09
FI953838A0 (fi) 1995-08-14
PL310171A1 (en) 1995-11-27
EP0683780A1 (de) 1995-11-29
RU2136682C1 (ru) 1999-09-10
CZ287313B6 (en) 2000-10-11
CA2156078A1 (en) 1994-08-18
MY111201A (en) 1999-09-30
AU6039194A (en) 1994-08-29
NO953187L (no) 1995-08-14
TW293008B (enExample) 1996-12-11
JP3447292B2 (ja) 2003-09-16
HUT72436A (en) 1996-04-29
IL108520A0 (en) 1994-05-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ALTANA PHARMA AG, 78467 KONSTANZ, DE

8327 Change in the person/name/address of the patent owner

Owner name: NYCOMED GMBH, 78467 KONSTANZ, DE

8339 Ceased/non-payment of the annual fee