DE3886221D1 - VERFAHREN ZUR HERSTELLUNG VON PROTEINPRODUKTEN IN -i(ASPERGILLUS) UND PROMOTOREN ZUR VERWENDUNG IN -i(ASPERGILLUS). - Google Patents

VERFAHREN ZUR HERSTELLUNG VON PROTEINPRODUKTEN IN -i(ASPERGILLUS) UND PROMOTOREN ZUR VERWENDUNG IN -i(ASPERGILLUS).

Info

Publication number
DE3886221D1
DE3886221D1 DE88908169T DE3886221T DE3886221D1 DE 3886221 D1 DE3886221 D1 DE 3886221D1 DE 88908169 T DE88908169 T DE 88908169T DE 3886221 T DE3886221 T DE 3886221T DE 3886221 D1 DE3886221 D1 DE 3886221D1
Authority
DE
Germany
Prior art keywords
aspergillus
promotors
protein products
producing protein
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE88908169T
Other languages
English (en)
Other versions
DE3886221T2 (de
DE3886221T3 (de
Inventor
Helle Woeldike
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26067550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3886221(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DK460987A external-priority patent/DK460987D0/da
Priority claimed from DK512687A external-priority patent/DK512687D0/da
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE3886221D1 publication Critical patent/DE3886221D1/de
Publication of DE3886221T2 publication Critical patent/DE3886221T2/de
Application granted granted Critical
Publication of DE3886221T3 publication Critical patent/DE3886221T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C12N9/242—Fungal source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE3886221T 1987-09-04 1988-09-02 VERFAHREN ZUR HERSTELLUNG VON PROTEINPRODUKTEN IN -i(ASPERGILLUS) UND PROMOTOREN ZUR VERWENDUNG IN -i(ASPERGILLUS). Expired - Lifetime DE3886221T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK460987A DK460987D0 (da) 1987-09-04 1987-09-04 Fremstilling af proteiner.
DK512687A DK512687D0 (da) 1987-09-29 1987-09-29 Fremstilling af proteiner
PCT/DK1988/000145 WO1989001969A1 (en) 1987-09-04 1988-09-02 Process for the production of protein products in aspergillus and promoters for use in aspergillus

Publications (3)

Publication Number Publication Date
DE3886221D1 true DE3886221D1 (de) 1994-01-20
DE3886221T2 DE3886221T2 (de) 1994-05-19
DE3886221T3 DE3886221T3 (de) 2000-12-21

Family

ID=26067550

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3886221T Expired - Lifetime DE3886221T3 (de) 1987-09-04 1988-09-02 VERFAHREN ZUR HERSTELLUNG VON PROTEINPRODUKTEN IN -i(ASPERGILLUS) UND PROMOTOREN ZUR VERWENDUNG IN -i(ASPERGILLUS).

Country Status (4)

Country Link
EP (1) EP0383779B2 (de)
JP (1) JP2703598B2 (de)
DE (1) DE3886221T3 (de)
WO (1) WO1989001969A1 (de)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
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US5536661A (en) * 1987-03-10 1996-07-16 Novo Nordisk A/S Process for the production of protein products in aspergillus
US5766912A (en) 1986-03-17 1998-06-16 Novo Nordisk A/S Humicola lipase produced in aspergillus
CA1341226C (en) * 1988-08-16 2001-05-01 Wim Van Hartingsveldt Gene replacement as a tool for the construction of aspergillus strains
IL94183A (en) 1989-05-05 2003-09-17 Baylor College Medicine cDNA SEQUENCE CODING FOR HUMAN LACTOFERRIN PROTEIN OR PORTION THEREOF AND LACTOFERRIN PROTEIN PRODUCED FROM SAID SEQUENCE
US6100054A (en) * 1989-05-05 2000-08-08 Baylor College Of Medicine Production for recombinant lactoferrin and lactoferrin polypeptides using DNA sequences in various organisms
US5766939A (en) * 1989-05-05 1998-06-16 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
US5571691A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
US5849881A (en) * 1989-05-05 1998-12-15 Baylor College Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using cDNA sequences in various organisms
JPH05505308A (ja) * 1990-03-13 1993-08-12 ハワイ・バイオテクノロジー・グループ・インコーポレイテツド アオパンカビ発現システム
FR2666590A1 (fr) * 1990-09-11 1992-03-13 Sanofi Sa Adn recombinant codant pour un precurseur de l'endothiapepsine, vecteur d'expression, bacteries et cellules eucaryotes transformees.
US5914306A (en) 1991-05-01 1999-06-22 Novo Nordisk A/S Stabilized enzymes
ZA932568B (en) * 1992-04-24 1993-11-12 Baylor College Midecine A Non Production of recombinant human lactoferrin
WO1995000652A1 (en) * 1993-06-18 1995-01-05 Ciba-Geigy Ag Chimeric plant genes possessing independent regulatory sequences
GB9316883D0 (en) * 1993-08-13 1993-09-29 Univ Leeds Production of heterologous peptices
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US7816129B2 (en) 1994-07-29 2010-10-19 Ab Enzymes Gmbh Production and secretion of proteins of bacterial origin in filamentous fungi
US5935836A (en) * 1994-07-29 1999-08-10 Rohm Enzyme Finland Oy Actinomadura xylanase sequences and methods of use
US6111081A (en) * 1996-05-31 2000-08-29 Baylor College Of Medicine Lactoferrin variants and uses thereof
GB9704157D0 (en) * 1997-02-28 1997-04-16 Danisco Expression element
AU7398100A (en) * 1999-09-13 2001-04-17 Concordia University A multifunctional system for the efficient manipulation of protein expression infilamentous fungi and method using same
AR026433A1 (es) 1999-11-10 2003-02-12 Novozymes As Variantes de alfa-amilasa tipo fungamyl
PL371800A1 (en) 2001-03-22 2005-06-27 Novo Nordisk Health Care Ag Coagulation factor vii derivatives
US7063962B2 (en) 2001-07-20 2006-06-20 Novozymes A/S DNA sequences for regulating transcription
ES2376694T3 (es) 2001-09-27 2012-03-16 Novo Nordisk Health Care Ag Polipã‰ptidos del factor vii de coagulaciã“n humano.
AU2003206683A1 (en) * 2002-02-19 2003-09-09 Novozymes A/S Expression cloning methods in filamentous fungi
WO2004106533A1 (en) 2003-05-30 2004-12-09 Novozymes A/S Alcohol product processes
WO2005003311A2 (en) 2003-06-25 2005-01-13 Novozymes A/S Enzymes for starch processing
DK2336308T3 (da) 2003-06-25 2014-11-10 Novozymes As Enzymer til forarbejdning af stivelse
CN101870729A (zh) 2003-09-09 2010-10-27 诺和诺德医疗保健公司 凝固因子ⅶ多肽
JP5452869B2 (ja) 2004-12-22 2014-03-26 ノボザイムス アクティーゼルスカブ デンプン加工法
EP1856263A1 (de) * 2005-03-01 2007-11-21 DSMIP Assets B.V. Aspergillus-promotoren zur expression eines gens in einer pilzzelle
US20090055942A1 (en) 2005-09-14 2009-02-26 Novo Nordisk Healthcare A/G Human Coagulation Factor VII Polypeptides
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DK2147107T3 (da) 2007-05-09 2011-10-24 Novozymes As Fremgangsmåde til ekspressionskloning, som er egnet til selektion af bibliotekskloner, der producerer et polypeptid af interesse
US9695549B2 (en) 2007-09-03 2017-07-04 Norozymes Als Detoxifying and recycling of washing solution used in pretreatment of lignocellulose-containing materials
CN102083991A (zh) 2008-06-23 2011-06-01 诺维信公司 生产发酵产物的方法
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EP2358878B1 (de) 2008-11-20 2014-10-15 Novozymes Inc. Polypeptide mit amylolytischer verstärkungsaktivität und dafür codierende polynukloeotide
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EP2451961A1 (de) 2009-07-07 2012-05-16 Novozymes A/S Verfahren zur behandlung eines substrats mit einem enzym
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CN107353327A (zh) * 2017-03-30 2017-11-17 南京百斯杰生物工程有限公司 植酸酶在黑曲霉中表达
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ATE161881T1 (de) * 1985-04-15 1998-01-15 Gist Brocades Nv Verwendung von promotoren von filamentösen pilzen
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Also Published As

Publication number Publication date
JP2703598B2 (ja) 1998-01-26
DE3886221T2 (de) 1994-05-19
EP0383779B2 (de) 2000-05-31
WO1989001969A1 (en) 1989-03-09
EP0383779A1 (de) 1990-08-29
DE3886221T3 (de) 2000-12-21
EP0383779B1 (de) 1993-12-08
JPH04503150A (ja) 1992-06-11

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Owner name: NOVOZYMES A/S, BAGSVAERD, DK