DE3875765T2 - Fluor enthaltende atriale natriuretische peptide. - Google Patents

Fluor enthaltende atriale natriuretische peptide.

Info

Publication number
DE3875765T2
DE3875765T2 DE8888104365T DE3875765T DE3875765T2 DE 3875765 T2 DE3875765 T2 DE 3875765T2 DE 8888104365 T DE8888104365 T DE 8888104365T DE 3875765 T DE3875765 T DE 3875765T DE 3875765 T2 DE3875765 T2 DE 3875765T2
Authority
DE
Germany
Prior art keywords
ser
peptide
formula
arg
phe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888104365T
Other languages
German (de)
English (en)
Other versions
DE3875765D1 (enrdf_load_stackoverflow
Inventor
Mahesh H Goghari
Sumanas Rakhit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Mega Boehringer Ingelheim Research Inc
Original Assignee
Bio Mega Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Mega Inc filed Critical Bio Mega Inc
Publication of DE3875765D1 publication Critical patent/DE3875765D1/de
Application granted granted Critical
Publication of DE3875765T2 publication Critical patent/DE3875765T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/58Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE8888104365T 1987-03-25 1988-03-18 Fluor enthaltende atriale natriuretische peptide. Expired - Fee Related DE3875765T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA532982 1987-03-25
CA542192 1987-07-15

Publications (2)

Publication Number Publication Date
DE3875765D1 DE3875765D1 (enrdf_load_stackoverflow) 1992-12-17
DE3875765T2 true DE3875765T2 (de) 1993-03-25

Family

ID=25671281

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888104365T Expired - Fee Related DE3875765T2 (de) 1987-03-25 1988-03-18 Fluor enthaltende atriale natriuretische peptide.

Country Status (7)

Country Link
US (1) US5095004A (enrdf_load_stackoverflow)
EP (1) EP0283956B1 (enrdf_load_stackoverflow)
JP (1) JPS646296A (enrdf_load_stackoverflow)
AU (1) AU605259B2 (enrdf_load_stackoverflow)
DE (1) DE3875765T2 (enrdf_load_stackoverflow)
IL (1) IL85728A (enrdf_load_stackoverflow)
NZ (1) NZ223885A (enrdf_load_stackoverflow)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376635A (en) * 1987-03-15 1994-12-27 Bio-Mega/Boehringer Ingelheim Research Inc. Fluorine containing atrial natriuretic peptides
JP2539940Y2 (ja) * 1993-03-23 1997-07-02 村田機械株式会社 ブレイダー
US5846932A (en) * 1993-11-12 1998-12-08 Genentech, Inc. Receptor specific atrial natriuretic peptides
US5665704A (en) * 1993-11-12 1997-09-09 Genentech, Inc. Receptor specific atrial natriuretic peptides
US6525022B1 (en) 1993-11-12 2003-02-25 Genentech, Inc. Receptor specific atrial natriuretic peptides
FI974436A7 (fi) * 1995-06-06 1998-01-27 Pfizer Substituoituja N-(indoli-2-karbonyyli)-glysiiniamideja ja -johdannaisi a glykogeenifosforylaasi-inhibiittoreina
WO1997019908A1 (en) * 1995-11-29 1997-06-05 Nihon Nohyaku Co., Ltd. Phenylalanine derivatives, optically active substances, salts or coordination compounds thereof, and their use as fungicides
US6277877B1 (en) 2000-08-15 2001-08-21 Pfizer, Inc. Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors
EP2004633A4 (en) * 2006-03-30 2009-08-26 Palatin Technologies Inc LINEAR NATRIURETIC PEPTIDE CONSTRUCTS
US8580746B2 (en) * 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
US7622440B2 (en) 2006-03-30 2009-11-24 Palatin Technologies, Inc. Cyclic natriuretic peptide constructs

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004870A1 (en) * 1984-04-19 1985-11-07 Biotechnology Research Partners, Ltd. Novel atrial natriuretic/vasodilator polypeptides
AU4292785A (en) * 1984-04-24 1985-11-15 Salk Institute For Biological Studies, The Atrial peptide analogs
JPS61233698A (ja) * 1985-04-09 1986-10-17 Ajinomoto Co Inc 新規ペプチド
JPH0672157B2 (ja) * 1984-08-29 1994-09-14 味の素株式会社 新規ペプチド
DE3443257A1 (de) * 1984-11-28 1986-05-28 Bissendorf Peptide GmbH, 3002 Wedemark Mittel enthaltend vollsynthetisches alpha-humanes atriales natriuretisches peptid (alpha-hanap)
JPS61161299A (ja) * 1985-01-04 1986-07-21 メルク エンド カムパニ− インコ−ポレ−テツド 心房ペプチド
US4652549A (en) * 1985-01-22 1987-03-24 Merck & Co., Inc. Cardiac anti-hypertrophic agents
JPS61243100A (ja) * 1985-04-19 1986-10-29 アボツト ラボラトリ−ズ Anp誘導体
AU8108687A (en) * 1986-09-30 1988-04-21 Smithkline Beckman Corporation Cell transfection
EP0263908B1 (en) * 1986-10-15 1991-09-25 Battelle Memorial Institute Method for the production of proteins by means of inducible expression systems in genetically modified eukaryotic host-cells multiplicated in-vivo

Also Published As

Publication number Publication date
AU1316788A (en) 1988-11-24
JPS646296A (en) 1989-01-10
DE3875765D1 (enrdf_load_stackoverflow) 1992-12-17
IL85728A0 (en) 1988-08-31
EP0283956A2 (en) 1988-09-28
US5095004A (en) 1992-03-10
EP0283956A3 (en) 1990-04-11
EP0283956B1 (en) 1992-11-11
AU605259B2 (en) 1991-01-10
NZ223885A (en) 1989-10-27
IL85728A (en) 1993-01-14

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC., LAVAL

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee