DE3839401A1 - N-heterocyclische alkohol-derivate - Google Patents

N-heterocyclische alkohol-derivate

Info

Publication number
DE3839401A1
DE3839401A1 DE3839401A DE3839401A DE3839401A1 DE 3839401 A1 DE3839401 A1 DE 3839401A1 DE 3839401 A DE3839401 A DE 3839401A DE 3839401 A DE3839401 A DE 3839401A DE 3839401 A1 DE3839401 A1 DE 3839401A1
Authority
DE
Germany
Prior art keywords
rest means
rest
mmol
ethyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE3839401A
Other languages
German (de)
English (en)
Inventor
Iii Harold Norris Weller
Denis Evan Ryono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of DE3839401A1 publication Critical patent/DE3839401A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE3839401A 1987-11-23 1988-11-22 N-heterocyclische alkohol-derivate Ceased DE3839401A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12430987A 1987-11-23 1987-11-23

Publications (1)

Publication Number Publication Date
DE3839401A1 true DE3839401A1 (de) 1989-06-01

Family

ID=22414093

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3839401A Ceased DE3839401A1 (de) 1987-11-23 1988-11-22 N-heterocyclische alkohol-derivate

Country Status (6)

Country Link
JP (1) JP2650117B2 (it)
CA (1) CA1329680C (it)
DE (1) DE3839401A1 (it)
FR (1) FR2623507B1 (it)
GB (1) GB2212804B (it)
IT (1) IT1227717B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0427939A3 (en) * 1989-10-11 1991-11-06 American Cyanamid Company Renin inhibitors
US5149692A (en) * 1989-12-21 1992-09-22 Warner-Lambert Company Bisalkoxyphosphinyl compounds as renin inhibitors
IL99389A0 (en) * 1990-09-17 1992-08-18 Fujisawa Pharmaceutical Co Amino acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
AU680829B2 (en) * 1992-09-25 1997-08-14 Bio-Mega/Boehringer Ingelheim Research Inc. Renin inhibiting N-(2-amino-2-oxoethyl)butanediamide derivatives
NZ255300A (en) * 1992-09-25 1997-05-26 Bio Mega Boehringer Ingelheim N-(hydroxyethyl)butane diamide derivatives, preparation and pharmaceutical compositions thereof
CA2246725A1 (en) * 1996-02-19 1997-08-21 Japan Tobacco Inc. Therapeutic agent for diabetes
FR2752422B1 (fr) * 1996-08-16 1998-11-06 Lipha Composition pharmaceutique contenant des acides 4-oxo-butanoiques
JP4524015B2 (ja) * 1999-11-17 2010-08-11 キッセイ薬品工業株式会社 （２ｓ）−２−ベンジルコハク酸モノエステルの有機アミン塩およびその製造方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0231919A2 (en) * 1986-02-03 1987-08-12 E.R. Squibb & Sons, Inc. N-Heterocyclic alcohol renin inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87614A0 (en) * 1987-09-16 1989-01-31 Abbott Lab Peptidylheterocycles

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0231919A2 (en) * 1986-02-03 1987-08-12 E.R. Squibb & Sons, Inc. N-Heterocyclic alcohol renin inhibitors

Also Published As

Publication number Publication date
GB2212804B (en) 1991-07-31
FR2623507A1 (fr) 1989-05-26
GB8827050D0 (en) 1988-12-21
IT8822714A0 (it) 1988-11-23
IT1227717B (it) 1991-05-06
CA1329680C (en) 1994-05-17
GB2212804A (en) 1989-08-02
JP2650117B2 (ja) 1997-09-03
FR2623507B1 (fr) 1995-03-31
JPH01165571A (ja) 1989-06-29

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Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: TAUCHNER, P., DIPL.-CHEM. DR.RER.NAT. HEUNEMANN, D

8110 Request for examination paragraph 44
8131 Rejection