FR2623507B1 - Derives d'alcools n-heterocycliques a action therapeutique - Google Patents

Derives d'alcools n-heterocycliques a action therapeutique

Info

Publication number
FR2623507B1
FR2623507B1 FR8815275A FR8815275A FR2623507B1 FR 2623507 B1 FR2623507 B1 FR 2623507B1 FR 8815275 A FR8815275 A FR 8815275A FR 8815275 A FR8815275 A FR 8815275A FR 2623507 B1 FR2623507 B1 FR 2623507B1
Authority
FR
France
Prior art keywords
derivatives
therapeutic action
heterocyclic alcohols
heterocyclic
alcohols
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8815275A
Other languages
English (en)
Other versions
FR2623507A1 (fr
Inventor
Weller Harold Norris
Ryono Denis Evan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2623507A1 publication Critical patent/FR2623507A1/fr
Application granted granted Critical
Publication of FR2623507B1 publication Critical patent/FR2623507B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8815275A 1987-11-23 1988-11-23 Derives d'alcools n-heterocycliques a action therapeutique Expired - Lifetime FR2623507B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12430987A 1987-11-23 1987-11-23

Publications (2)

Publication Number Publication Date
FR2623507A1 FR2623507A1 (fr) 1989-05-26
FR2623507B1 true FR2623507B1 (fr) 1995-03-31

Family

ID=22414093

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8815275A Expired - Lifetime FR2623507B1 (fr) 1987-11-23 1988-11-23 Derives d'alcools n-heterocycliques a action therapeutique

Country Status (6)

Country Link
JP (1) JP2650117B2 (fr)
CA (1) CA1329680C (fr)
DE (1) DE3839401A1 (fr)
FR (1) FR2623507B1 (fr)
GB (1) GB2212804B (fr)
IT (1) IT1227717B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0427939A3 (en) * 1989-10-11 1991-11-06 American Cyanamid Company Renin inhibitors
US5149692A (en) * 1989-12-21 1992-09-22 Warner-Lambert Company Bisalkoxyphosphinyl compounds as renin inhibitors
IL99389A0 (en) * 1990-09-17 1992-08-18 Fujisawa Pharmaceutical Co Amino acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
JP3490442B2 (ja) * 1992-09-25 2004-01-26 ベーリンガー インゲルハイム (カナダ) リミテッド レニン阻害n−(2−アミノ−2−オキソエチル)ブタンジアミド誘導体
CA2143301C (fr) * 1992-09-25 1998-04-21 Paul Cates Anderson Derives de n-(hydroxyethyle)butanediamide utilises comme inhibiteurs de la renine
EP0885869A1 (fr) * 1996-02-19 1998-12-23 Japan Tobacco Inc. Agent therapeutique contre le diabete
FR2752422B1 (fr) * 1996-08-16 1998-11-06 Lipha Composition pharmaceutique contenant des acides 4-oxo-butanoiques
JP4524015B2 (ja) * 1999-11-17 2010-08-11 キッセイ薬品工業株式会社 (2s)−2−ベンジルコハク酸モノエステルの有機アミン塩およびその製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors
IL87614A0 (en) * 1987-09-16 1989-01-31 Abbott Lab Peptidylheterocycles

Also Published As

Publication number Publication date
JPH01165571A (ja) 1989-06-29
CA1329680C (fr) 1994-05-17
IT8822714A0 (it) 1988-11-23
DE3839401A1 (de) 1989-06-01
GB2212804B (en) 1991-07-31
FR2623507A1 (fr) 1989-05-26
JP2650117B2 (ja) 1997-09-03
IT1227717B (it) 1991-05-06
GB2212804A (en) 1989-08-02
GB8827050D0 (en) 1988-12-21

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