FR2578255B1 - Acides 8-oxo-2-oxa-1-azabicyclo(4.2.0)octane-3-carboxyliques a action therapeutique - Google Patents

Acides 8-oxo-2-oxa-1-azabicyclo(4.2.0)octane-3-carboxyliques a action therapeutique

Info

Publication number
FR2578255B1
FR2578255B1 FR8602834A FR8602834A FR2578255B1 FR 2578255 B1 FR2578255 B1 FR 2578255B1 FR 8602834 A FR8602834 A FR 8602834A FR 8602834 A FR8602834 A FR 8602834A FR 2578255 B1 FR2578255 B1 FR 2578255B1
Authority
FR
France
Prior art keywords
azabicyclo
oxa
octane
oxo
carboxylic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8602834A
Other languages
English (en)
Other versions
FR2578255A1 (fr
Inventor
David R Kronenthal
Paula L Kuester
William H Koster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2578255A1 publication Critical patent/FR2578255A1/fr
Application granted granted Critical
Publication of FR2578255B1 publication Critical patent/FR2578255B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR8602834A 1985-03-01 1986-02-28 Acides 8-oxo-2-oxa-1-azabicyclo(4.2.0)octane-3-carboxyliques a action therapeutique Expired FR2578255B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/707,357 US4574153A (en) 1985-03-01 1985-03-01 8-Oxo-2-oxa-1-azabicyclo(4.2.0)octane-3-carboxylic acids

Publications (2)

Publication Number Publication Date
FR2578255A1 FR2578255A1 (fr) 1986-09-05
FR2578255B1 true FR2578255B1 (fr) 1989-01-06

Family

ID=24841378

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8602834A Expired FR2578255B1 (fr) 1985-03-01 1986-02-28 Acides 8-oxo-2-oxa-1-azabicyclo(4.2.0)octane-3-carboxyliques a action therapeutique

Country Status (6)

Country Link
US (1) US4574153A (fr)
JP (1) JPS61212588A (fr)
DE (1) DE3606584A1 (fr)
FR (1) FR2578255B1 (fr)
GB (1) GB2171701B (fr)
IT (1) IT1188557B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089609A (en) * 1986-03-13 1992-02-18 Schering Corporation 4-benzoyl azetidinones
US5008404A (en) * 1988-08-01 1991-04-16 Schering Corporation Preparation of azetidinones via novel protected intermediates
US4827006A (en) * 1986-03-13 1989-05-02 Schering Corporation Preparation of azetidinones via novel protected intermediates
US8263579B2 (en) * 2011-01-24 2012-09-11 Piramal Healthcare Limited Anti-inflammatory compounds
AU2012277481B2 (en) * 2011-06-30 2016-10-06 Godavari Biorefineries Limited Synthesis of cleistanthin A an derivatives thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458071A (en) * 1982-11-16 1984-07-03 Eli Lilly And Company Process for 1-oxa-β-lactams

Also Published As

Publication number Publication date
GB8604686D0 (en) 1986-04-03
US4574153A (en) 1986-03-04
JPS61212588A (ja) 1986-09-20
IT8619594A1 (it) 1987-08-28
GB2171701A (en) 1986-09-03
DE3606584A1 (de) 1986-09-04
IT1188557B (it) 1988-01-20
FR2578255A1 (fr) 1986-09-05
IT8619594A0 (it) 1986-02-28
GB2171701B (en) 1988-10-12

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Legal Events

Date Code Title Description
ST Notification of lapse