FR2558836B1 - Analogues d'oxaprostaglandines a substituant 7-oxabicyloheptane, a action therapeutique - Google Patents

Analogues d'oxaprostaglandines a substituant 7-oxabicyloheptane, a action therapeutique

Info

Publication number
FR2558836B1
FR2558836B1 FR8500991A FR8500991A FR2558836B1 FR 2558836 B1 FR2558836 B1 FR 2558836B1 FR 8500991 A FR8500991 A FR 8500991A FR 8500991 A FR8500991 A FR 8500991A FR 2558836 B1 FR2558836 B1 FR 2558836B1
Authority
FR
France
Prior art keywords
oxabicyloheptane
oxaprostaglandin
analogs
substituted
therapeutic action
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8500991A
Other languages
English (en)
Other versions
FR2558836A1 (fr
Inventor
Steven E Hall
Martin F Haslanger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2558836A1 publication Critical patent/FR2558836A1/fr
Application granted granted Critical
Publication of FR2558836B1 publication Critical patent/FR2558836B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8500991A 1984-01-26 1985-01-24 Analogues d'oxaprostaglandines a substituant 7-oxabicyloheptane, a action therapeutique Expired FR2558836B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/574,000 US4526900A (en) 1984-01-26 1984-01-26 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease

Publications (2)

Publication Number Publication Date
FR2558836A1 FR2558836A1 (fr) 1985-08-02
FR2558836B1 true FR2558836B1 (fr) 1986-12-19

Family

ID=24294275

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8500991A Expired FR2558836B1 (fr) 1984-01-26 1985-01-24 Analogues d'oxaprostaglandines a substituant 7-oxabicyloheptane, a action therapeutique

Country Status (7)

Country Link
US (1) US4526900A (fr)
JP (1) JPS60178874A (fr)
CA (1) CA1257285A (fr)
DE (1) DE3502512A1 (fr)
FR (1) FR2558836B1 (fr)
GB (1) GB2153352B (fr)
IT (1) IT1208493B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1256887A (fr) * 1983-03-14 1989-07-04 Steven E. Hall 7-oxabicycloheptanes substitues analogues de prostaglandines
JPH01145594A (ja) * 1987-12-01 1989-06-07 Nippon Denso Co Ltd 対人追従装置
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑-磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
WO1980001381A1 (fr) * 1979-01-05 1980-07-10 R Jones Bicyclo (2,2,1) heptanes et hep-2-enes substitues
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA829068B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease
CA1256887A (fr) * 1983-03-14 1989-07-04 Steven E. Hall 7-oxabicycloheptanes substitues analogues de prostaglandines

Also Published As

Publication number Publication date
GB2153352A (en) 1985-08-21
IT8519224A0 (it) 1985-01-25
US4526900A (en) 1985-07-02
DE3502512A1 (de) 1985-08-01
JPS60178874A (ja) 1985-09-12
GB2153352B (en) 1987-10-07
GB8501266D0 (en) 1985-02-20
FR2558836A1 (fr) 1985-08-02
IT1208493B (it) 1989-07-10
CA1257285A (fr) 1989-07-11

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Legal Events

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ST Notification of lapse