FR2611718B1 - Analogues d'amino prostaglandines 7-oxabicycloheptane substitues, a action therapeutique - Google Patents
Analogues d'amino prostaglandines 7-oxabicycloheptane substitues, a action therapeutiqueInfo
- Publication number
- FR2611718B1 FR2611718B1 FR888802609A FR8802609A FR2611718B1 FR 2611718 B1 FR2611718 B1 FR 2611718B1 FR 888802609 A FR888802609 A FR 888802609A FR 8802609 A FR8802609 A FR 8802609A FR 2611718 B1 FR2611718 B1 FR 2611718B1
- Authority
- FR
- France
- Prior art keywords
- oxabicycloheptane
- analogs
- substituted amino
- therapeutic action
- prostaglandin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/020,640 US4749715A (en) | 1987-03-02 | 1987-03-02 | 7-oxabicycloheptane substituted amino prostaglandin analogs |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2611718A1 FR2611718A1 (fr) | 1988-09-09 |
FR2611718B1 true FR2611718B1 (fr) | 1990-01-12 |
Family
ID=21799754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR888802609A Expired - Fee Related FR2611718B1 (fr) | 1987-03-02 | 1988-03-02 | Analogues d'amino prostaglandines 7-oxabicycloheptane substitues, a action therapeutique |
Country Status (6)
Country | Link |
---|---|
US (1) | US4749715A (fr) |
JP (1) | JPS63243086A (fr) |
DE (1) | DE3806549A1 (fr) |
FR (1) | FR2611718B1 (fr) |
GB (1) | GB2201675B (fr) |
IT (1) | IT1215973B (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1332607C (fr) * | 1988-07-19 | 1994-10-18 | Masayuki Narisada | Derives alkenyltetrazole |
US5451605A (en) * | 1993-12-30 | 1995-09-19 | Allergan, Inc. | 1,2-epoxycyclohexanyl and bicyclic aromatic substituted ethyne compounds having retinoid-like biological activity |
US6395897B1 (en) | 1999-03-02 | 2002-05-28 | Boehringer Ingelheim Pharmaceuticals, Inc. | Nitrile compounds useful as reversible inhibitors of #9 cathepsin 5 |
US6420364B1 (en) | 1999-09-13 | 2002-07-16 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compound useful as reversible inhibitors of cysteine proteases |
US20030129186A1 (en) | 2001-07-25 | 2003-07-10 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
PT1889198E (pt) | 2005-04-28 | 2015-03-06 | Proteus Digital Health Inc | Sistema fármaco-informático |
WO2008036682A2 (fr) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Traitement des troubles hépatiques par l'administration de conjugués de protéine associée au récepteur (rap) |
JP5277665B2 (ja) * | 2008-03-06 | 2013-08-28 | 東ソー株式会社 | 環状脂肪族ジアミンの製造方法 |
PT2398500T (pt) | 2009-02-20 | 2019-06-14 | 2 Bbb Medicines B V | Sistema de entrega de medicamentos à base de glutationas |
ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3980691A (en) * | 1969-03-14 | 1976-09-14 | The Upjohn Company | Racemic prostaglandins of the 2-series and analogs thereof |
US4220594A (en) * | 1977-11-04 | 1980-09-02 | E. R. Squibb & Sons, Inc. | Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol |
US4187236A (en) * | 1977-11-04 | 1980-02-05 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane compounds |
US4143054A (en) * | 1977-11-04 | 1979-03-06 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane- and 7-oxabicycloheptene compounds |
US4254044A (en) * | 1977-11-04 | 1981-03-03 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds |
EP0013607B1 (fr) * | 1979-01-05 | 1983-03-23 | National Research Development Corporation | Bicyclo (2,2,1)heptanes et bicyclo (2,2,1) hept-2-ènes substitués et leurs compositions pharmaceutiques |
US4228180A (en) * | 1979-11-01 | 1980-10-14 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs |
ZA829068B (en) * | 1980-07-01 | 1983-02-23 | Nat Res Dev | Prostaglandins |
JPS58502148A (ja) * | 1981-12-23 | 1983-12-15 | ナシヨナル リサ−チ デイベロツプメント コ−ポレイシヨン | プロスタグランジン |
US4416896A (en) * | 1982-05-17 | 1983-11-22 | E. R. Squibb & Sons, Inc. | 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease |
US4456615A (en) * | 1982-10-25 | 1984-06-26 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction |
US4456617A (en) * | 1983-01-12 | 1984-06-26 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction |
US4542157A (en) * | 1984-04-27 | 1985-09-17 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
US4607048A (en) * | 1985-05-16 | 1986-08-19 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted aryl amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction |
US4663336A (en) * | 1985-07-01 | 1987-05-05 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted diamide and its congener prostaglandin analogs useful in the treatment of thrombotic disease |
US4639461A (en) * | 1985-10-28 | 1987-01-27 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted keto-amide prostaglandin analogs useful in the treatment of thrombotic disease |
US4638012A (en) * | 1985-11-05 | 1987-01-20 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane α-substituted ketone prostaglandin analogs useful in the treatment of thrombotic disease |
US4687865A (en) * | 1986-06-04 | 1987-08-18 | E. R. Squibb & Sons, Inc. | Process for preparing 7-oxabicycloheptane amino-alcohol intermediates useful in making thromboxane A2 receptor antagonists |
-
1987
- 1987-03-02 US US07/020,640 patent/US4749715A/en not_active Expired - Lifetime
-
1988
- 1988-02-29 GB GB8804750A patent/GB2201675B/en not_active Expired - Fee Related
- 1988-03-01 DE DE3806549A patent/DE3806549A1/de not_active Withdrawn
- 1988-03-01 IT IT8819603A patent/IT1215973B/it active
- 1988-03-02 FR FR888802609A patent/FR2611718B1/fr not_active Expired - Fee Related
- 1988-03-02 JP JP63050559A patent/JPS63243086A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US4749715A (en) | 1988-06-07 |
JPS63243086A (ja) | 1988-10-07 |
IT8819603A0 (it) | 1988-03-01 |
GB2201675B (en) | 1990-10-03 |
FR2611718A1 (fr) | 1988-09-09 |
GB2201675A (en) | 1988-09-07 |
GB8804750D0 (en) | 1988-03-30 |
DE3806549A1 (de) | 1988-09-15 |
IT1215973B (it) | 1990-02-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |