IT1215973B - Analoghi della ammino prostaglandina 7 ossabicicloeptansostituiti. - Google Patents

Analoghi della ammino prostaglandina 7 ossabicicloeptansostituiti.

Info

Publication number
IT1215973B
IT1215973B IT8819603A IT1960388A IT1215973B IT 1215973 B IT1215973 B IT 1215973B IT 8819603 A IT8819603 A IT 8819603A IT 1960388 A IT1960388 A IT 1960388A IT 1215973 B IT1215973 B IT 1215973B
Authority
IT
Italy
Prior art keywords
oxabicycleeptans
prostaglandina
analogues
amino
replaced
Prior art date
Application number
IT8819603A
Other languages
English (en)
Other versions
IT8819603A0 (it
Inventor
Steven Edward Hall
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8819603A0 publication Critical patent/IT8819603A0/it
Application granted granted Critical
Publication of IT1215973B publication Critical patent/IT1215973B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8819603A 1987-03-02 1988-03-01 Analoghi della ammino prostaglandina 7 ossabicicloeptansostituiti. IT1215973B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/020,640 US4749715A (en) 1987-03-02 1987-03-02 7-oxabicycloheptane substituted amino prostaglandin analogs

Publications (2)

Publication Number Publication Date
IT8819603A0 IT8819603A0 (it) 1988-03-01
IT1215973B true IT1215973B (it) 1990-02-22

Family

ID=21799754

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8819603A IT1215973B (it) 1987-03-02 1988-03-01 Analoghi della ammino prostaglandina 7 ossabicicloeptansostituiti.

Country Status (6)

Country Link
US (1) US4749715A (it)
JP (1) JPS63243086A (it)
DE (1) DE3806549A1 (it)
FR (1) FR2611718B1 (it)
GB (1) GB2201675B (it)
IT (1) IT1215973B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332607C (en) * 1988-07-19 1994-10-18 Masayuki Narisada Alkenyltetrazole derivatives
US5451605A (en) * 1993-12-30 1995-09-19 Allergan, Inc. 1,2-epoxycyclohexanyl and bicyclic aromatic substituted ethyne compounds having retinoid-like biological activity
CA2360740A1 (en) 1999-03-02 2000-09-08 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as reversible inhibitors of cathepsin s
US6420364B1 (en) * 1999-09-13 2002-07-16 Boehringer Ingelheim Pharmaceuticals, Inc. Compound useful as reversible inhibitors of cysteine proteases
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
JP5277665B2 (ja) * 2008-03-06 2013-08-28 東ソー株式会社 環状脂肪族ジアミンの製造方法
ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
US8445002B2 (en) 2009-05-06 2013-05-21 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980691A (en) * 1969-03-14 1976-09-14 The Upjohn Company Racemic prostaglandins of the 2-series and analogs thereof
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
EP0045118B1 (en) * 1979-01-05 1984-04-04 National Research Development Corporation Intermediates for the synthesis of bicyclo (2,2,1) heptanes and bicyclo (2,2,1) hept-2z-enes
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA829068B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
EP0082646B1 (en) * 1981-12-23 1989-11-15 National Research Development Corporation Prostaglandins
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease
US4456615A (en) * 1982-10-25 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4456617A (en) * 1983-01-12 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4607048A (en) * 1985-05-16 1986-08-19 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted aryl amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4663336A (en) * 1985-07-01 1987-05-05 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diamide and its congener prostaglandin analogs useful in the treatment of thrombotic disease
US4639461A (en) * 1985-10-28 1987-01-27 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted keto-amide prostaglandin analogs useful in the treatment of thrombotic disease
US4638012A (en) * 1985-11-05 1987-01-20 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane α-substituted ketone prostaglandin analogs useful in the treatment of thrombotic disease
US4687865A (en) * 1986-06-04 1987-08-18 E. R. Squibb & Sons, Inc. Process for preparing 7-oxabicycloheptane amino-alcohol intermediates useful in making thromboxane A2 receptor antagonists

Also Published As

Publication number Publication date
FR2611718A1 (fr) 1988-09-09
GB2201675B (en) 1990-10-03
JPS63243086A (ja) 1988-10-07
IT8819603A0 (it) 1988-03-01
GB8804750D0 (en) 1988-03-30
FR2611718B1 (fr) 1990-01-12
US4749715A (en) 1988-06-07
GB2201675A (en) 1988-09-07
DE3806549A1 (de) 1988-09-15

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950330