DE3781878T2 - Antibiotikum-a10255-komplex und faktoren, verfahren, mikroorganismen fuer seine herstellung. - Google Patents

Antibiotikum-a10255-komplex und faktoren, verfahren, mikroorganismen fuer seine herstellung.

Info

Publication number
DE3781878T2
DE3781878T2 DE8787310953T DE3781878T DE3781878T2 DE 3781878 T2 DE3781878 T2 DE 3781878T2 DE 8787310953 T DE8787310953 T DE 8787310953T DE 3781878 T DE3781878 T DE 3781878T DE 3781878 T2 DE3781878 T2 DE 3781878T2
Authority
DE
Germany
Prior art keywords
factor
complex
antibiotic
dimethyl sulfoxide
approximately
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787310953T
Other languages
German (de)
English (en)
Other versions
DE3781878D1 (de
Inventor
Laverne Dwaine Boeck
Godfrey, Jr
Marvin Martin Hoehn
Herbert Andrew Kirst
Karl Heinz Michel
Eugene Thomas Seno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE3781878D1 publication Critical patent/DE3781878D1/de
Publication of DE3781878T2 publication Critical patent/DE3781878T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8787310953T 1986-12-15 1987-12-14 Antibiotikum-a10255-komplex und faktoren, verfahren, mikroorganismen fuer seine herstellung. Expired - Fee Related DE3781878T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94189486A 1986-12-15 1986-12-15
US94147386A 1986-12-15 1986-12-15

Publications (2)

Publication Number Publication Date
DE3781878D1 DE3781878D1 (de) 1992-10-29
DE3781878T2 true DE3781878T2 (de) 1993-03-11

Family

ID=27130157

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787310953T Expired - Fee Related DE3781878T2 (de) 1986-12-15 1987-12-14 Antibiotikum-a10255-komplex und faktoren, verfahren, mikroorganismen fuer seine herstellung.

Country Status (15)

Country Link
EP (1) EP0274873B1 (enExample)
JP (1) JPS63258585A (enExample)
KR (1) KR880007553A (enExample)
CN (1) CN1023758C (enExample)
AU (1) AU604806B2 (enExample)
DE (1) DE3781878T2 (enExample)
DK (1) DK654987A (enExample)
ES (1) ES2052584T3 (enExample)
GR (1) GR3006408T3 (enExample)
HU (1) HU199559B (enExample)
IE (1) IE60394B1 (enExample)
IL (1) IL84819A (enExample)
MX (1) MX170925B (enExample)
NZ (1) NZ222895A (enExample)
PT (1) PT86364B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25145A (en) * 1986-12-15 1991-02-19 Laverne Dwaine Boeck Process for producing the a10255 complex and corresponding microorganism
US5229362A (en) * 1986-12-15 1993-07-20 Eli Lilly And Company Antibiotic A10255 complex and factors, and process and production therefor
DE3851268T2 (de) * 1987-06-19 1995-01-26 Sandoz Ag Zyklische Peptolide.
IT1234197B (it) * 1988-06-14 1992-05-06 Mini Ricerca Scient Tecnolog Antibiotici ottenuti mediante coltivazione aerobica controllata dello streptomyces s.p. ncib 12629
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
SI1413331T1 (sl) 2001-01-26 2008-02-29 Schering Corp Kombinacije fenofibrata peroksisomskega proliferator aktivirajocega receptorja (PPAR) z ezetimib zaviralcem absorpcije sterola za vaskularne indikacije
JP4711600B2 (ja) 2001-01-26 2011-06-29 シェーリング コーポレイション シトステロール血症の処置のための置換アゼチジノン化合物の使用
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7132415B2 (en) 2001-09-21 2006-11-07 Schering Corporation Methods and therapeutic combinations for the treatment of xanthoma using sterol absorption inhibitors
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
CA2504878A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorption inhibitors for the treatment of demyelination
CA2513793A1 (en) 2003-02-18 2004-09-02 Incro Limited Dispenser pump
CN100439361C (zh) 2003-03-07 2008-12-03 先灵公司 取代的2-吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
CN1756755A (zh) 2003-03-07 2006-04-05 先灵公司 取代的2－吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP4589919B2 (ja) 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
BR112012004643A2 (pt) * 2009-09-02 2019-09-24 Piramal Life Scinces Ltd compostos antibióticos

Also Published As

Publication number Publication date
EP0274873A3 (en) 1989-08-09
CN87108341A (zh) 1988-08-10
IE60394B1 (en) 1994-07-13
PT86364A (en) 1988-01-01
MX170925B (es) 1993-09-22
EP0274873A2 (en) 1988-07-20
HU199559B (en) 1990-02-28
IE873390L (en) 1988-06-15
EP0274873B1 (en) 1992-09-23
KR880007553A (ko) 1988-08-27
CN1023758C (zh) 1994-02-16
DE3781878D1 (de) 1992-10-29
IL84819A (en) 1993-07-08
HUT49376A (en) 1989-09-28
JPS63258585A (ja) 1988-10-26
NZ222895A (en) 1992-08-26
GR3006408T3 (enExample) 1993-06-21
ES2052584T3 (es) 1994-07-16
PT86364B (pt) 1990-11-07
AU8249387A (en) 1988-07-28
DK654987D0 (da) 1987-12-14
DK654987A (da) 1988-09-23
AU604806B2 (en) 1991-01-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee