DE3766300D1 - Verfahren zur herstellung von imidazopyridinen. - Google Patents

Verfahren zur herstellung von imidazopyridinen.

Info

Publication number
DE3766300D1
DE3766300D1 DE8787401353T DE3766300T DE3766300D1 DE 3766300 D1 DE3766300 D1 DE 3766300D1 DE 8787401353 T DE8787401353 T DE 8787401353T DE 3766300 T DE3766300 T DE 3766300T DE 3766300 D1 DE3766300 D1 DE 3766300D1
Authority
DE
Germany
Prior art keywords
imidazopyridines
producing
producing imidazopyridines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787401353T
Other languages
English (en)
Inventor
Guy Rossey
David Long
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of DE3766300D1 publication Critical patent/DE3766300D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
DE8787401353T 1986-06-27 1987-06-17 Verfahren zur herstellung von imidazopyridinen. Expired - Lifetime DE3766300D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8609330A FR2600650B1 (fr) 1986-06-27 1986-06-27 Procede de preparation d'imidazopyridines et composes intermediaires

Publications (1)

Publication Number Publication Date
DE3766300D1 true DE3766300D1 (de) 1991-01-03

Family

ID=9336785

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787401353T Expired - Lifetime DE3766300D1 (de) 1986-06-27 1987-06-17 Verfahren zur herstellung von imidazopyridinen.

Country Status (21)

Country Link
US (1) US4794185A (de)
EP (1) EP0251859B1 (de)
JP (1) JPH0653740B2 (de)
KR (1) KR940006594B1 (de)
AR (1) AR243188A1 (de)
AT (1) ATE58537T1 (de)
AU (1) AU7477287A (de)
CA (1) CA1324138C (de)
DE (1) DE3766300D1 (de)
DK (1) DK169505B1 (de)
ES (1) ES2019646B3 (de)
FI (1) FI872850A (de)
FR (1) FR2600650B1 (de)
GR (1) GR3001118T3 (de)
HU (1) HU204826B (de)
IE (1) IE60467B1 (de)
IL (1) IL82982A (de)
NO (1) NO167392C (de)
NZ (1) NZ220853A (de)
PT (1) PT85188B (de)
ZA (1) ZA874643B (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2032455T3 (es) * 1986-01-22 1993-02-16 Synthelabo Procedimiento para preparar derivados de 3-acilaminometil-imidazo (-1,2-a)piridinas.
FR2615513B1 (fr) * 1987-05-21 1989-07-13 Synthelabo Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
AU4060599A (en) 1998-06-09 1999-12-30 Takeda Chemical Industries Ltd. Pharmaceutical composition for treating or preventing sleep disorders
ES2151834B1 (es) * 1998-08-06 2001-08-16 Sint Quimica Sa Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
PT1038875E (pt) 1999-03-25 2003-10-31 Synthon Bv Derivados de imidazopiridina e processo para os preparar
ES2240074T3 (es) * 1999-03-25 2005-10-16 Synthon B.V. Sales de zolpidem.
US6333345B1 (en) * 1999-05-14 2001-12-25 Sepracor, Inc. Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en) 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
EP1272181A2 (de) * 2000-04-13 2003-01-08 Synthon B.V. Arzneizubereitungen mit gesteuerter wirkstoffabgabe enthaltend ein hypnotikum
PT1475093E (pt) * 2000-04-24 2006-11-30 Teva Pharma Hemitartarato de zolpidem micronizado
EP1475093B1 (de) * 2000-04-24 2006-09-06 Teva Pharmaceutical Industries Ltd. Mikronisierter zolpidem Hemitartrat
IT1318624B1 (it) * 2000-07-14 2003-08-27 Dinamite Dipharma S P A In For Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
WO2002014306A1 (en) * 2000-08-17 2002-02-21 Cilag Ag Process for the preparation of imidazopyridines
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
US20020183522A1 (en) 2001-05-03 2002-12-05 Markus Sauter Process for preparing zolpidem
DE10121638A1 (de) * 2001-05-03 2002-11-14 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Imidazopyridinen
US6861525B2 (en) * 2002-07-15 2005-03-01 Scinopharm Taiwan, Ltd. Process for the preparation imidazo[1,2-A]pyridine-3-acetamides
DE60326270D1 (de) 2002-12-18 2009-04-02 Mallinckrodt Inc Synthese von heteroaryl acetamiden
US20040241100A1 (en) * 2003-03-17 2004-12-02 Fabre Kramer Pharmaceutical, Inc. Nasally administrable compositions of zolpidem and methods of use
GB0311457D0 (en) * 2003-05-19 2003-06-25 Sciencom Ltd New therapeutic use
CA2548917C (en) 2003-12-11 2014-09-23 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
AU2005262622A1 (en) * 2004-06-22 2006-01-19 Mallinckrodt Inc. Synthesis of heteroaryl acetamides from reaction mixtures having reduced water content
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258357A3 (de) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenese mit Acetylcholinesterasehemmer
US20080293946A1 (en) * 2005-10-03 2008-11-27 Cheng Brian K Process for Preparing Zolpidem Hemitartrate and Tartrate Polymorphs
JP2009511627A (ja) * 2005-10-17 2009-03-19 マリンクロッド・インコーポレイテッド 錠剤マトリックスにおけるゾルピデムの多形転移
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
WO2007065559A1 (en) 2005-11-18 2007-06-14 Synthon B.V. Zolpidem tablets
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2021000A2 (de) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenese mittels angiotensin-modulation
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
US7998971B2 (en) * 2006-09-08 2011-08-16 Braincells Inc. Combinations containing a 4-acylaminopyridine derivative
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
CN103360387B (zh) * 2012-03-28 2016-12-14 江苏豪森药业集团有限公司 一种制备化合物唑吡坦的方法
KR101704589B1 (ko) * 2016-07-12 2017-02-08 주식회사 뉴트라팜텍 후박 추출물 및 신이 추출물의 혼합물을 유효성분으로 함유하는 치주조직 성장 촉진용 및 치주염 예방 또는 치료용 약학적 조성물
CN107793415A (zh) * 2016-12-01 2018-03-13 湖南省食品药品检验研究院 酒石酸唑吡坦杂质的合成方法
CN106749237A (zh) * 2016-12-28 2017-05-31 江苏豪森药业集团有限公司 酒石酸唑吡坦及其中间体的制备方法
CN114057726A (zh) * 2020-07-31 2022-02-18 株洲千金药业股份有限公司 一种唑吡坦盐酸盐的合成方法
CN114057727B (zh) * 2020-07-31 2024-02-27 株洲千金药业股份有限公司 一种唑吡坦中间体的合成方法
CN114057725B (zh) * 2020-07-31 2024-01-16 株洲千金药业股份有限公司 一种酒石酸唑吡坦的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68765B (de) * 1979-06-20 1982-02-17 Rohm & Haas
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
AU7477287A (en) 1988-01-07
FR2600650B1 (fr) 1988-09-09
AR243188A1 (es) 1993-07-30
JPS638384A (ja) 1988-01-14
DK328187A (da) 1987-12-28
ATE58537T1 (de) 1990-12-15
CA1324138C (en) 1993-11-09
NO167392B (no) 1991-07-22
JPH0653740B2 (ja) 1994-07-20
ZA874643B (en) 1988-02-24
EP0251859A3 (en) 1989-07-19
PT85188B (pt) 1990-03-30
FI872850A (fi) 1987-12-28
NO872682L (no) 1987-12-28
DK169505B1 (da) 1994-11-14
FR2600650A1 (fr) 1987-12-31
DK328187D0 (da) 1987-06-26
EP0251859A2 (de) 1988-01-07
KR880000433A (ko) 1988-03-25
NO872682D0 (no) 1987-06-26
NZ220853A (en) 1989-09-27
FI872850A0 (fi) 1987-06-26
IL82982A (en) 1992-03-29
PT85188A (fr) 1987-07-01
IE871723L (en) 1987-12-27
HU204826B (en) 1992-02-28
ES2019646B3 (es) 1991-07-01
GR3001118T3 (en) 1992-05-12
US4794185A (en) 1988-12-27
IE60467B1 (en) 1994-07-13
IL82982A0 (en) 1987-12-20
HUT44547A (en) 1988-03-28
EP0251859B1 (de) 1990-11-22
KR940006594B1 (ko) 1994-07-23
NO167392C (no) 1991-10-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-SYNTHELABO, PARIS, FR

8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS, PARIS, FR