DK328187A - Fremgangsmaade til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmaaden - Google Patents
Fremgangsmaade til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmaadenInfo
- Publication number
- DK328187A DK328187A DK328187A DK328187A DK328187A DK 328187 A DK328187 A DK 328187A DK 328187 A DK328187 A DK 328187A DK 328187 A DK328187 A DK 328187A DK 328187 A DK328187 A DK 328187A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- imidazopyridines
- intermediates
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8609330 | 1986-06-27 | ||
| FR8609330A FR2600650B1 (fr) | 1986-06-27 | 1986-06-27 | Procede de preparation d'imidazopyridines et composes intermediaires |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK328187D0 DK328187D0 (da) | 1987-06-26 |
| DK328187A true DK328187A (da) | 1987-12-28 |
| DK169505B1 DK169505B1 (da) | 1994-11-14 |
Family
ID=9336785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK328187A DK169505B1 (da) | 1986-06-27 | 1987-06-26 | Fremgangsmåde til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmåden |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4794185A (da) |
| EP (1) | EP0251859B1 (da) |
| JP (1) | JPH0653740B2 (da) |
| KR (1) | KR940006594B1 (da) |
| AR (1) | AR243188A1 (da) |
| AT (1) | ATE58537T1 (da) |
| AU (1) | AU7477287A (da) |
| CA (1) | CA1324138C (da) |
| DE (1) | DE3766300D1 (da) |
| DK (1) | DK169505B1 (da) |
| ES (1) | ES2019646B3 (da) |
| FI (1) | FI872850A (da) |
| FR (1) | FR2600650B1 (da) |
| GR (1) | GR3001118T3 (da) |
| HU (1) | HU204826B (da) |
| IE (1) | IE60467B1 (da) |
| IL (1) | IL82982A (da) |
| NO (1) | NO167392C (da) |
| NZ (1) | NZ220853A (da) |
| PT (1) | PT85188B (da) |
| ZA (1) | ZA874643B (da) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3769333D1 (de) * | 1986-01-22 | 1991-05-23 | Synthelabo | Acylaminomethylimidazo(1,2-a)pyrimidinderivate, ihre herstellung und therapeutische verwendung. |
| FR2615513B1 (fr) * | 1987-05-21 | 1989-07-13 | Synthelabo | Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique |
| WO1999063977A2 (en) | 1998-06-09 | 1999-12-16 | Takeda Chemical Industries, Ltd. | Pharmaceutical combination comprising a tricyclic compound and at least one of zolpidem, zopiclone, triazolam and brotizolam for treating or preventing sleep disorders |
| ES2151834B1 (es) * | 1998-08-06 | 2001-08-16 | Sint Quimica Sa | Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales. |
| NL1014634C1 (nl) * | 1999-03-25 | 2000-08-03 | Synthon Bv | Zolpidemzouten. |
| EP1038875B1 (en) | 1999-03-25 | 2003-06-04 | Synthon B.V. | Imidazopyridine derivatives and process for making them |
| US6333345B1 (en) * | 1999-05-14 | 2001-12-25 | Sepracor, Inc. | Methods of using and compositions comprising N-desmethylzolpidem |
| US6399621B1 (en) | 1999-08-10 | 2002-06-04 | American Cyanamid Company | N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto |
| US20030091632A1 (en) * | 1999-08-26 | 2003-05-15 | Neurocrine Biosciences, Inc. | Controlled-release sedative-hypnotic compositions and methods related thereto |
| US6485746B1 (en) | 2000-08-25 | 2002-11-26 | Neurocrine Biosciences, Inc. | Controlled-release sedative-hypnotic compositions and methods related thereto |
| US6384221B1 (en) * | 1999-09-02 | 2002-05-07 | Neurocrine Biosciences, Inc. | Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto |
| WO2001078725A2 (en) * | 2000-04-13 | 2001-10-25 | Synthon B.V. | Modified release formulations containing a hypnotic agent |
| EP1600159A1 (en) * | 2000-04-24 | 2005-11-30 | Teva Pharmaceutical Industries Ltd | A method for synthesizing different Zolpidem hemitartrate derivatives |
| DE04010651T1 (de) * | 2000-04-24 | 2005-09-01 | Teva Pharmaceutical Industries Ltd. | Mikronisiertes Zolpidem-Hemitartrat |
| IT1318624B1 (it) * | 2000-07-14 | 2003-08-27 | Dinamite Dipharma S P A In For | Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi. |
| WO2002014306A1 (en) * | 2000-08-17 | 2002-02-21 | Cilag Ag | Process for the preparation of imidazopyridines |
| US6596731B2 (en) | 2001-03-27 | 2003-07-22 | Hoffmann-La Roche Inc. | Substituted imidazo[1,2-A] pyridine derivatives |
| US20020183522A1 (en) | 2001-05-03 | 2002-12-05 | Markus Sauter | Process for preparing zolpidem |
| DE10121638A1 (de) * | 2001-05-03 | 2002-11-14 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Imidazopyridinen |
| DE60320808D1 (de) * | 2002-07-15 | 2008-06-19 | Scinopharm Taiwan Ltd | Verfahren zur herstellung von imidazo(1,2-a)pyridin-3-acetamiden |
| ES2320758T3 (es) * | 2002-12-18 | 2009-05-28 | Mallinckrodt Inc. | Sintesis de heteroaril acetamidas. |
| US20040241100A1 (en) * | 2003-03-17 | 2004-12-02 | Fabre Kramer Pharmaceutical, Inc. | Nasally administrable compositions of zolpidem and methods of use |
| GB0311457D0 (en) * | 2003-05-19 | 2003-06-25 | Sciencom Ltd | New therapeutic use |
| DK1691811T3 (da) | 2003-12-11 | 2014-10-20 | Sunovion Pharmaceuticals Inc | Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression |
| CN1972939A (zh) * | 2004-06-22 | 2007-05-30 | 马林克罗特公司 | 由具有减少的水含量的反应混合物合成杂芳基乙酰胺 |
| WO2006008636A2 (en) * | 2004-07-16 | 2006-01-26 | Ranbaxy Laboratories Limited | Processes for the preparation of zolpidem and its hemitartrate |
| EP2258357A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| WO2007025177A2 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| CA2624340A1 (en) * | 2005-10-03 | 2007-04-12 | Mallinckrodt Inc. | Process for preparing zolpidem hemitartrate and tartrate polymorphs |
| CA2626242A1 (en) * | 2005-10-17 | 2007-04-26 | Mallinckrodt Inc. | Polymorph transformation of zolpidem in tablet matrix |
| US7985756B2 (en) | 2005-10-21 | 2011-07-26 | Braincells Inc. | Modulation of neurogenesis by PDE inhibition |
| WO2007053596A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| EP1948132B1 (en) | 2005-11-18 | 2009-08-05 | Synhton B.V. | Zolpidem tablets |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| JP2009536667A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス，インコーポレイティド | ５ｈｔ受容体介在性の神経新生 |
| WO2007134136A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| BRPI0716604A2 (pt) * | 2006-09-08 | 2013-04-09 | Braincells Inc | combinaÇÕes contendo um derivado de 4-acilaminopiridina |
| US20080145425A1 (en) * | 2006-12-15 | 2008-06-19 | Pliva Research & Development Limited | Pharmaceutical composition of zolpidem |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| CN103360387B (zh) * | 2012-03-28 | 2016-12-14 | 江苏豪森药业集团有限公司 | 一种制备化合物唑吡坦的方法 |
| KR101704589B1 (ko) * | 2016-07-12 | 2017-02-08 | 주식회사 뉴트라팜텍 | 후박 추출물 및 신이 추출물의 혼합물을 유효성분으로 함유하는 치주조직 성장 촉진용 및 치주염 예방 또는 치료용 약학적 조성물 |
| CN107793415A (zh) * | 2016-12-01 | 2018-03-13 | 湖南省食品药品检验研究院 | 酒石酸唑吡坦杂质的合成方法 |
| CN106749237A (zh) * | 2016-12-28 | 2017-05-31 | 江苏豪森药业集团有限公司 | 酒石酸唑吡坦及其中间体的制备方法 |
| CN114057725B (zh) * | 2020-07-31 | 2024-01-16 | 株洲千金药业股份有限公司 | 一种酒石酸唑吡坦的合成方法 |
| CN114057726A (zh) * | 2020-07-31 | 2022-02-18 | 株洲千金药业股份有限公司 | 一种唑吡坦盐酸盐的合成方法 |
| CN114057727B (zh) * | 2020-07-31 | 2024-02-27 | 株洲千金药业股份有限公司 | 一种唑吡坦中间体的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR68765B (da) * | 1979-06-20 | 1982-02-17 | Rohm & Haas | |
| FR2492382A1 (fr) * | 1980-10-22 | 1982-04-23 | Synthelabo | Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique |
-
1986
- 1986-06-27 FR FR8609330A patent/FR2600650B1/fr not_active Expired
-
1987
- 1987-06-17 AT AT87401353T patent/ATE58537T1/de active
- 1987-06-17 ES ES87401353T patent/ES2019646B3/es not_active Expired - Lifetime
- 1987-06-17 EP EP87401353A patent/EP0251859B1/fr not_active Expired - Lifetime
- 1987-06-17 DE DE8787401353T patent/DE3766300D1/de not_active Expired - Lifetime
- 1987-06-24 IL IL82982A patent/IL82982A/xx not_active IP Right Cessation
- 1987-06-26 ZA ZA874643A patent/ZA874643B/xx unknown
- 1987-06-26 DK DK328187A patent/DK169505B1/da not_active IP Right Cessation
- 1987-06-26 FI FI872850A patent/FI872850A/fi not_active Application Discontinuation
- 1987-06-26 NO NO872682A patent/NO167392C/no not_active IP Right Cessation
- 1987-06-26 AU AU74772/87A patent/AU7477287A/en not_active Abandoned
- 1987-06-26 HU HU872909A patent/HU204826B/hu unknown
- 1987-06-26 IE IE172387A patent/IE60467B1/en not_active IP Right Cessation
- 1987-06-26 KR KR1019870006538A patent/KR940006594B1/ko not_active IP Right Cessation
- 1987-06-26 US US07/066,530 patent/US4794185A/en not_active Expired - Lifetime
- 1987-06-26 JP JP62160827A patent/JPH0653740B2/ja not_active Expired - Lifetime
- 1987-06-26 PT PT85188A patent/PT85188B/pt unknown
- 1987-06-26 AR AR87307995A patent/AR243188A1/es active
- 1987-06-26 NZ NZ220853A patent/NZ220853A/xx unknown
- 1987-06-26 CA CA000540712A patent/CA1324138C/en not_active Expired - Fee Related
-
1990
- 1990-11-28 GR GR90400982T patent/GR3001118T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4794185A (en) | 1988-12-27 |
| ATE58537T1 (de) | 1990-12-15 |
| JPH0653740B2 (ja) | 1994-07-20 |
| FI872850A0 (fi) | 1987-06-26 |
| JPS638384A (ja) | 1988-01-14 |
| EP0251859A3 (en) | 1989-07-19 |
| KR940006594B1 (ko) | 1994-07-23 |
| IE60467B1 (en) | 1994-07-13 |
| KR880000433A (ko) | 1988-03-25 |
| AU7477287A (en) | 1988-01-07 |
| HU204826B (en) | 1992-02-28 |
| GR3001118T3 (en) | 1992-05-12 |
| IL82982A (en) | 1992-03-29 |
| FR2600650B1 (fr) | 1988-09-09 |
| PT85188B (pt) | 1990-03-30 |
| AR243188A1 (es) | 1993-07-30 |
| PT85188A (fr) | 1987-07-01 |
| EP0251859A2 (fr) | 1988-01-07 |
| NO872682D0 (no) | 1987-06-26 |
| NO872682L (no) | 1987-12-28 |
| ES2019646B3 (es) | 1991-07-01 |
| IE871723L (en) | 1987-12-27 |
| NO167392C (no) | 1991-10-30 |
| NO167392B (no) | 1991-07-22 |
| ZA874643B (en) | 1988-02-24 |
| DK169505B1 (da) | 1994-11-14 |
| HUT44547A (en) | 1988-03-28 |
| EP0251859B1 (fr) | 1990-11-22 |
| CA1324138C (en) | 1993-11-09 |
| DK328187D0 (da) | 1987-06-26 |
| FR2600650A1 (fr) | 1987-12-31 |
| FI872850A (fi) | 1987-12-28 |
| DE3766300D1 (de) | 1991-01-03 |
| NZ220853A (en) | 1989-09-27 |
| IL82982A0 (en) | 1987-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |