DE3765009D1 - Verfahren zur herstellung von 4-acetoxy-3-hydroxyaethyl-azetidin-2-one-derivaten. - Google Patents

Verfahren zur herstellung von 4-acetoxy-3-hydroxyaethyl-azetidin-2-one-derivaten.

Info

Publication number
DE3765009D1
DE3765009D1 DE8787106234A DE3765009A DE3765009D1 DE 3765009 D1 DE3765009 D1 DE 3765009D1 DE 8787106234 A DE8787106234 A DE 8787106234A DE 3765009 A DE3765009 A DE 3765009A DE 3765009 D1 DE3765009 D1 DE 3765009D1
Authority
DE
Germany
Prior art keywords
hydroxyaethyl
azetidine
acetoxy
derivatives
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787106234A
Other languages
English (en)
Inventor
Kazunori Kan
Noboru Ueyama
Isao Sada
Takehisa Ohashi
Kiyoshi Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP61101856A priority Critical patent/JPH0830057B2/ja
Priority to JP27062286 priority
Priority to JP62028942A priority patent/JPH0655717B2/ja
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Application granted granted Critical
Publication of DE3765009D1 publication Critical patent/DE3765009D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE8787106234A 1986-04-30 1987-04-29 Verfahren zur herstellung von 4-acetoxy-3-hydroxyaethyl-azetidin-2-one-derivaten. Expired - Fee Related DE3765009D1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP61101856A JPH0830057B2 (ja) 1986-04-30 1986-04-30 ４―アセトキシ―３―ヒドロキシエチルアゼチジン―２―オン誘導体の製造方法
JP27062286 1986-11-13
JP62028942A JPH0655717B2 (ja) 1986-11-13 1987-02-09 ４−アセトキシ−３−ヒドロキシエチルアゼチジン−２−オン誘導体の製造方法

Publications (1)

Publication Number Publication Date
DE3765009D1 true DE3765009D1 (de) 1990-10-25

Family

ID=27286381

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787106234A Expired - Fee Related DE3765009D1 (de) 1986-04-30 1987-04-29 Verfahren zur herstellung von 4-acetoxy-3-hydroxyaethyl-azetidin-2-one-derivaten.

Country Status (6)

Country Link
US (1) US4914200A (de)
EP (1) EP0247378B1 (de)
AU (1) AU601180B2 (de)
CA (1) CA1256444A (de)
DE (1) DE3765009D1 (de)
ES (1) ES2017956B3 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1017991B (zh) * 1987-02-20 1992-08-26 钟渊化学工业株式会社 4-乙酰氧基-3-羟乙基氮杂环丁-2-酮衍生物的制备方法
CA2000565C (en) * 1988-10-19 1998-06-23 Masaji Ishiguro Process for the preparation of 4-acyloxy-2-azetidinone derivatives
US5204460A (en) * 1988-11-29 1993-04-20 Takasago International Corporation Ruthenium catalyzed process for preparing 4-acetoxyazetidinones
DE68920298T2 (de) 1988-11-29 1995-07-27 Takasago Perfumery Co Ltd Verfahren zur Herstellung von 4-Acetoxyazetidinonen.
KR0130463B1 (ko) * 1989-05-31 1998-04-09 로버트 엠. 존슨 신규 β-락탐을 사용하는 탁솔 제조방법
JP2969387B2 (ja) * 1991-04-18 1999-11-02 高砂香料工業株式会社 置換アセトキシアゼチジノン類及び４−アシルオキシアゼチジノン類の製造方法
US5728850A (en) * 1991-09-23 1998-03-17 Florida State University Taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5283253A (en) * 1991-09-23 1994-02-01 Florida State University Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
US6018073A (en) * 1991-09-23 2000-01-25 Florida State University Tricyclic taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US6495704B1 (en) 1991-09-23 2002-12-17 Florida State University 9-desoxotaxanes and process for the preparation of 9-desoxotaxanes
US6335362B1 (en) 1991-09-23 2002-01-01 Florida State University Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
US5739362A (en) * 1991-09-23 1998-04-14 Florida State University Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US7074945B2 (en) 1991-09-23 2006-07-11 Florida State University Metal alkoxide taxane derivatives
US5489601A (en) * 1991-09-23 1996-02-06 Florida State University Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them
US5350866A (en) * 1991-09-23 1994-09-27 Bristol-Myers Squibb Company 10-desacetoxytaxol derivatives
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US6005138A (en) * 1991-09-23 1999-12-21 Florida State University Tricyclic taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5430160A (en) * 1991-09-23 1995-07-04 Florida State University Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides
US5998656A (en) * 1991-09-23 1999-12-07 Florida State University C10 tricyclic taxanes
US5714513A (en) * 1991-09-23 1998-02-03 Florida State University C10 taxane derivatives and pharmaceutical compositions
US5654447A (en) * 1991-09-23 1997-08-05 Florida State University Process for the preparation of 10-desacetoxybaccatin III
US6710191B2 (en) 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
US5284865A (en) 1991-09-23 1994-02-08 Holton Robert A Cyclohexyl substituted taxanes and pharmaceutical compositions containing them
US5274124A (en) * 1991-09-23 1993-12-28 Florida State University Metal alkoxides
US6066747A (en) * 1993-03-05 2000-05-23 Florida State University Process for the preparation of 9-desoxotaxanes
CN1221412A (zh) 1996-05-06 1999-06-30 佛罗里达州立大学 1－脱氧浆果赤霉素ⅲ,1－脱氧紫杉醇和1－脱氧紫杉醇类似物及其制备方法
KR20050044621A (ko) 2001-11-30 2005-05-12 브리스톨-마이어스 스큅 컴퍼니 파클리탁셀 용매화물
PL227494B1 (pl) 2012-12-21 2017-12-29 Inst Chemii Organicznej Polskiej Akademii Nauk A method for producing a 2-azetidinone derivative and a method for producing intermediates
CN109096150B (zh) * 2018-09-26 2020-08-25 中国科学技术大学 一种光诱导非金属催化制备β-氨基酮的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770855C3 (de) * 1961-03-23 1974-10-10 Chemie Gruenenthal Gmbh, 5190 Stolberg
AU8605382A (en) * 1981-07-15 1983-01-20 Sumitomo Chemical Company, Limited Penicillins and azetidinones
CA1190236A (en) * 1981-10-23 1985-07-09 Edward J.J. Grabowski Antibiotic synthesis
DE3375481D1 (en) * 1982-10-13 1988-03-03 Sumitomo Pharma Beta-lactam compounds and production thereof
GB8321004D0 (en) * 1983-08-04 1983-09-07 Erba Farmitalia Azetidinones
US4596677A (en) * 1984-04-06 1986-06-24 Bristol-Myers Company Anhydropenicillin intermediates
CA1256443A (en) * 1984-07-05 1989-06-27 Takehisa Ohashi Process for preparing 4-acetoxy-3- hydroxyethylazetidin-2-one derivatives
JPS6118791A (en) * 1984-07-05 1986-01-27 Kanegafuchi Chem Ind Co Ltd Novel beta-lactam compound and preparation thereof
DE3587546D1 (de) * 1984-10-01 1993-09-30 Ciba Geigy Verfahren zur Herstellung von optisch aktiven Acyloxyazetidinonen.
IT1197873B (it) * 1986-10-15 1988-12-21 Erba Farmitalia Procedimento per la preparazione di azetidinoni

Also Published As

Publication number Publication date
ES2017956B3 (es) 1991-03-16
CA1256444A (en) 1989-06-27
CA1256444A1 (de)
EP0247378A1 (de) 1987-12-02
EP0247378B1 (de) 1990-09-19
AU601180B2 (en) 1990-09-06
US4914200A (en) 1990-04-03
AU7214087A (en) 1987-11-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee