DE3751893T2 - Polypeptid und dessen Herstellung - Google Patents

Polypeptid und dessen Herstellung

Info

Publication number
DE3751893T2
DE3751893T2 DE3751893T DE3751893T DE3751893T2 DE 3751893 T2 DE3751893 T2 DE 3751893T2 DE 3751893 T DE3751893 T DE 3751893T DE 3751893 T DE3751893 T DE 3751893T DE 3751893 T2 DE3751893 T2 DE 3751893T2
Authority
DE
Germany
Prior art keywords
rat
kinase
disease
agent
signal transduction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3751893T
Other languages
English (en)
Other versions
DE3751893D1 (de
Inventor
Yoshitaka Ono
Tsutomu Kurokawa
Koichi Igarashi
Yasutomi Nishizuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE3751893D1 publication Critical patent/DE3751893D1/de
Publication of DE3751893T2 publication Critical patent/DE3751893T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE3751893T 1986-06-27 1987-06-26 Polypeptid und dessen Herstellung Expired - Lifetime DE3751893T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP14938586 1986-06-27
JP21794486 1986-09-18
JP28187086 1986-11-28
JP4016087 1987-02-25

Publications (2)

Publication Number Publication Date
DE3751893D1 DE3751893D1 (de) 1996-10-10
DE3751893T2 true DE3751893T2 (de) 1997-01-16

Family

ID=27460860

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3751893T Expired - Lifetime DE3751893T2 (de) 1986-06-27 1987-06-26 Polypeptid und dessen Herstellung
DE3752391T Expired - Lifetime DE3752391T2 (de) 1986-06-27 1987-06-26 Rattenproteinkinase C und Verfahren zur Herstellung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE3752391T Expired - Lifetime DE3752391T2 (de) 1986-06-27 1987-06-26 Rattenproteinkinase C und Verfahren zur Herstellung

Country Status (7)

Country Link
US (1) US5219748A (de)
EP (2) EP0686695B1 (de)
JP (2) JP2593476B2 (de)
AT (2) ATE142256T1 (de)
CA (1) CA1341288C (de)
DE (2) DE3751893T2 (de)
ES (1) ES2093600T3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988001303A1 (en) * 1986-08-13 1988-02-25 Genetics Institute, Inc. Protein kinase c enzymes
EP0358325A1 (de) * 1988-08-10 1990-03-14 Takeda Chemical Industries, Ltd. Herstellung von Proteinkinase C durch Hefe
JPH0536077U (ja) * 1991-10-22 1993-05-18 蔡 憲堂 騒音防止手段を有する空気ポンプ
US5459036A (en) * 1993-03-19 1995-10-17 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Extracellular signal-regulated kinase, sequences, and methods of production and use
ATE265537T1 (de) * 1996-03-19 2004-05-15 Millennium Pharm Inc Kinase für die stellen-spezifische phosphorylierung von i-kappa-b-alpha
BR9708390A (pt) * 1996-03-28 2000-01-04 Trustees O Boston University Método para identificar uma substância que altera a pigmentação nos melanócitos epidérmicos de vertebrados, substância que inibe, intensifica ou modula a fosforização da tirosinase mediada pela proteìna c-beta quinase, uso de um agente que modula ou inibe a fosforização de um resìduo de serina ou de treonina mediada pela proteìna c-beta quinase, uso em peptìdeo que especificamente interfere na fosforização de resìduos de serina/treonina mediada pela proteìna c-beta quinase, uso de uma construção de dna ou de um peptìdeo para fabricar um medicamento para diminuir a pigmentação na pela, cabelo, lã ou pelo de vertebrados e uso de uma substância que modula a fosforização da tirosinase mediada pela proteìna c-beta quinase.
US6150338A (en) * 1997-02-13 2000-11-21 Albert Einstein College Of Medicine Of Yeshiva University Gene therapy for alleviating erectile dysfunction
US7030096B1 (en) * 1997-02-13 2006-04-18 Albert Einstein College Of Medicine Of Yeshiva University Method of enhancing relaxation of penile smooth muscle by introduction of DNA encoding maxi-K potassium channel protein
US6271211B1 (en) 1997-02-13 2001-08-07 Albert Einstein College Of Medicine Of Yeshiva University Gene therapy for regulating penile smooth muscle tone
US6239117B1 (en) 1997-02-13 2001-05-29 Albert Einstein College Of Medicine Of Yeshiva University Gene therapy for regulating bladder smooth muscle tone
CN1311309A (zh) * 2000-03-02 2001-09-05 上海博德基因开发有限公司 一种新的多肽——人信号传导蛋白激酶17和编码这种多肽的多核苷酸
JP7362611B2 (ja) 2017-12-14 2023-10-17 ユニヴェルシテ・ドゥ・ストラスブール 非アルコール性脂肪肝疾患及び線維症の治療及び予防のためのペプチド

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988001303A1 (en) * 1986-08-13 1988-02-25 Genetics Institute, Inc. Protein kinase c enzymes

Also Published As

Publication number Publication date
ATE347592T1 (de) 2006-12-15
EP0251244A2 (de) 1988-01-07
ES2093600T3 (es) 1997-01-01
CA1341288C (en) 2001-09-04
JPS642572A (en) 1989-01-06
EP0251244A3 (en) 1989-02-08
JP2593476B2 (ja) 1997-03-26
JPH11123084A (ja) 1999-05-11
JP3146352B2 (ja) 2001-03-12
ATE142256T1 (de) 1996-09-15
US5219748A (en) 1993-06-15
EP0686695B1 (de) 2006-12-06
EP0251244B1 (de) 1996-09-04
DE3751893D1 (de) 1996-10-10
DE3752391T2 (de) 2007-12-13
EP0686695A1 (de) 1995-12-13
DE3752391D1 (de) 2007-01-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP