DE3532563C2 - - Google Patents

Info

Publication number
DE3532563C2
DE3532563C2 DE3532563A DE3532563A DE3532563C2 DE 3532563 C2 DE3532563 C2 DE 3532563C2 DE 3532563 A DE3532563 A DE 3532563A DE 3532563 A DE3532563 A DE 3532563A DE 3532563 C2 DE3532563 C2 DE 3532563C2
Authority
DE
Germany
Prior art keywords
carrier element
refractive index
light
indicator layer
excitation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3532563A
Other languages
German (de)
English (en)
Other versions
DE3532563A1 (de
Inventor
Herbert Dipl.-Ing. Dr. Kroneis
Helmut Dr. Graz At Offenbacher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avl AG
Original Assignee
Avl AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avl AG filed Critical Avl AG
Publication of DE3532563A1 publication Critical patent/DE3532563A1/de
Application granted granted Critical
Publication of DE3532563C2 publication Critical patent/DE3532563C2/de
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DE19853532563 1984-09-17 1985-09-12 Anordnung zur fluoreszenzoptischen messung von stoffkonzentrationen in einer probe Granted DE3532563A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0295584A AT383684B (de) 1984-09-17 1984-09-17 Anordnung zur fluoreszenzoptischen messung von stoffkonzentrationen in einer probe

Publications (2)

Publication Number Publication Date
DE3532563A1 DE3532563A1 (de) 1986-03-27
DE3532563C2 true DE3532563C2 (un) 1988-06-23

Family

ID=3543017

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19853532563 Granted DE3532563A1 (de) 1984-09-17 1985-09-12 Anordnung zur fluoreszenzoptischen messung von stoffkonzentrationen in einer probe

Country Status (4)

Country Link
US (1) US4703182A (un)
JP (1) JPH0678982B2 (un)
AT (1) AT383684B (un)
DE (1) DE3532563A1 (un)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT397458B (de) * 1992-09-25 1994-04-25 Avl Verbrennungskraft Messtech Sensoranordnung
DE19651935A1 (de) * 1996-12-14 1998-06-18 Ruckstuhl Thomas Detektionssystem für den optischen Nachweis von Molekülen
DE19735144A1 (de) * 1997-08-13 1999-02-25 Wolfram Dr Bohnenkamp Reflexionsfluorimeter
DE19947616A1 (de) * 1999-10-01 2001-05-03 Fraunhofer Ges Forschung Verfahren und Einrichtung zur Bestimmung von Substanzen, wie z. B. DNA-Sequenzen, in einer Probe

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3779807D1 (de) * 1986-04-23 1992-07-23 Avl Medical Instr Ag Sensorelement zur bestimmung von stoffkonzentrationen.
GB8629283D0 (en) * 1986-12-08 1987-01-14 Gen Electric Co Plc Radiation meters
JPH0799353B2 (ja) * 1987-03-31 1995-10-25 株式会社島津製作所 塩基配列決定装置
GB8714503D0 (en) * 1987-06-20 1987-07-22 Pa Consulting Services Detector
DK163194C (da) * 1988-12-22 1992-06-22 Radiometer As Fremgangsmaade ved fotometrisk in vitro bestemmelse af en blodgasparameter i en blodproeve
US5564419A (en) * 1987-11-25 1996-10-15 Radiometer A/S Method of photometric in vitro determination of the content of oxygen in a blood sample
US5166515A (en) * 1989-06-22 1992-11-24 Applied Research Systems Ars Holding, N.V. Method of optical analysis of a fluid including an optical waveguide
DE3931350A1 (de) * 1989-09-20 1991-03-28 Kaltenbach Martin Fuehrungshuelse zum einfuehren von kathetern
US5619586A (en) * 1990-12-20 1997-04-08 Thorn Emi Plc Method and apparatus for producing a directly viewable image of a fingerprint
US5192510A (en) * 1991-01-30 1993-03-09 E. I. Du Pont De Nemours And Company Apparatus for performing fluorescent assays which separates bulk and evanescent fluorescence
US5340715A (en) * 1991-06-07 1994-08-23 Ciba Corning Diagnostics Corp. Multiple surface evanescent wave sensor with a reference
US5156976A (en) * 1991-06-07 1992-10-20 Ciba Corning Diagnostics Corp. Evanescent wave sensor shell and apparatus
DE4128846C2 (de) * 1991-08-30 1994-07-14 Rainer Dr Klein Integriert optischer Stoffsensor
JPH07318481A (ja) * 1994-05-25 1995-12-08 Daikin Ind Ltd 光学的測定方法およびその装置
AT403745B (de) * 1996-02-29 1998-05-25 Avl Verbrennungskraft Messtech Messanordnung mit einem für anregungs- und messstrahlung transparentem trägerelement
WO1998023945A1 (en) * 1996-11-27 1998-06-04 Optical Analytic Inc. Perimeter light detection apparatus for enhanced collection of radiation
DE19702557C2 (de) * 1997-01-24 1999-06-17 Fraunhofer Ges Forschung Vorrichtung zur Erfassung von diffus emittiertem Licht
GB9903283D0 (en) * 1998-06-01 1999-04-07 Farfield Sensors Ltd Device
US6701032B1 (en) 1999-05-27 2004-03-02 Farfield Sensors Limited Device for housing a planar optical component
AT410600B (de) 1999-12-02 2003-06-25 Hoffmann La Roche Messkammer mit lumineszenzoptischen sensorelementen
DE10101576B4 (de) * 2001-01-15 2016-02-18 Presens Precision Sensing Gmbh Optischer Sensor und Sensorfeld
DE10245432A1 (de) * 2002-09-27 2004-04-08 Micronas Gmbh Verfahren und Vorrichtung zum Detektieren mindestens eines Lumineszenz-Stoffs
US7285789B2 (en) * 2003-06-06 2007-10-23 Oc Oerlikon Balzers Ag Optical device for surface-generated fluorescence
JP4558448B2 (ja) 2004-11-01 2010-10-06 テルモ株式会社 光導波路およびこの光導波路を用いた蛍光センサ
DE102006041756A1 (de) * 2006-09-04 2008-03-06 Robert Bosch Gmbh Werkzeugmaschinenüberwachungsvorrichtung
EP1944599A3 (en) 2007-01-11 2008-11-12 Fujifilm Corporation Fluorescence analysis apparatus
JP2013019819A (ja) * 2011-07-13 2013-01-31 Tokai Kogaku Kk 蛍光分析装置
GB2495703A (en) * 2011-10-12 2013-04-24 Crowcon Detection Instr Ltd Optical sensor without wavelength filter

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US360927A (en) * 1887-04-12 Dredger
GB1190583A (en) * 1966-10-19 1970-05-06 Mini Of Power Improvements in or relating to Gas Detectors
US3604927A (en) * 1966-11-16 1971-09-14 Block Engineering Total reflection fluorescence spectroscopy
US3612866A (en) * 1969-07-08 1971-10-12 Brian Stevens Instrument for determining oxygen quantities by measuring oxygen quenching of fluorescent radiation
US3669545A (en) * 1971-05-06 1972-06-13 Wilks Scientific Corp Apparatus and method for analysis by attenuated total reflection
US4031399A (en) * 1975-02-24 1977-06-21 Beckman Instruments, Inc. Fluorometer
DE2508637C3 (de) * 1975-02-28 1979-11-22 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Anordnung zur optischen Messung von Blutgasen
US4050895A (en) * 1975-09-26 1977-09-27 Monsanto Research Corporation Optical analytical device, waveguide and method
US4399099A (en) * 1979-09-20 1983-08-16 Buckles Richard G Optical fiber apparatus for quantitative analysis
US4564598A (en) * 1982-07-12 1986-01-14 Syntex (U.S.A.) Inc. Limited volume method for particle counting
US4532425A (en) * 1982-08-04 1985-07-30 Elscint Inc. Gamma camera with light guide having greater index of refraction
US4447546A (en) * 1982-08-23 1984-05-08 Myron J. Block Fluorescent immunoassay employing optical fiber in capillary tube
AT379688B (de) * 1982-11-22 1986-02-10 List Hans Sensorelement zur bestimmung des o2-gehaltes einer probe
AT377095B (de) * 1982-11-23 1985-02-11 List Hans Sensorelement zur bestimmung des o2-gehaltes einer probe sowie verfahren zur herstellung desselben

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT397458B (de) * 1992-09-25 1994-04-25 Avl Verbrennungskraft Messtech Sensoranordnung
DE19651935A1 (de) * 1996-12-14 1998-06-18 Ruckstuhl Thomas Detektionssystem für den optischen Nachweis von Molekülen
DE19735144A1 (de) * 1997-08-13 1999-02-25 Wolfram Dr Bohnenkamp Reflexionsfluorimeter
DE19735144C2 (de) * 1997-08-13 2000-02-24 Wolfram Bohnenkamp Reflexionsfluorimeter
US6252657B1 (en) 1997-08-13 2001-06-26 Wolfram Bohnenkamp Reflection fluorometer
DE19947616A1 (de) * 1999-10-01 2001-05-03 Fraunhofer Ges Forschung Verfahren und Einrichtung zur Bestimmung von Substanzen, wie z. B. DNA-Sequenzen, in einer Probe
DE19947616C2 (de) * 1999-10-01 2003-05-28 Fraunhofer Ges Forschung Verfahren zur Bestimmung von Substanzen, wie z.B. DNA-Sequenzen, in einer Probe und Vorrichtung zur Durchführung des Verfahrens

Also Published As

Publication number Publication date
AT383684B (de) 1987-08-10
ATA295584A (de) 1986-12-15
DE3532563A1 (de) 1986-03-27
US4703182A (en) 1987-10-27
JPH0678982B2 (ja) 1994-10-05
JPS6177745A (ja) 1986-04-21

Similar Documents

Publication Publication Date Title
DE3532563C2 (un)
EP0148497B1 (de) Vorrichtung zum Führen und Sammeln von Licht in der Fotometrie od. dgl.
DE10008006C2 (de) SPR-Sensor und SPR-Sensoranordnung
DE69816809T2 (de) Vorrichtung für fluoreszenznachweis
DE2114107B2 (de) Photometer
DE2645959A1 (de) Verfahren zur identifizierung von fluoreszenzstoffen
DE102006037506A1 (de) Refraktometer
DE3200391A1 (de) Optisches geraet fuer eine fluoreszenzpolarisationsvorrichtung
DE2103318B2 (de) Streuhchtphotometer
DE3213183C2 (un)
EP1054252B1 (de) Optische Messanordnung zur Bestimmung der Transmissions- und Streustrahlung
DE2136634A1 (de) Optische Anordnung fur ein Gerat zum Analysieren einer Probe durch Atomspek troskopie
DE3204146A1 (de) Verfahren zur messung der zusammensetzung und oertlichen konzentration von stoffen an oberflaechen
DE102021100321B4 (de) SPR-Sensoreinheit und Verfahren zur Bestimmung des Brechungsindex eines Proben-mediums sowie Messeinrichtung zur Erfassung der Dichte eines Messmediums
DE2556677A1 (de) Verfahren zur diskriminierung gegenueber den einfluessen von artefakten bei optischen untersuchungen unter ausnutzung von streuung und vorrichtung zur durchfuehrung des verfahrens
DE112021005257T5 (de) Optisches extinktionsspektrometer, optisches bauelement und verfahren zur optischen extinktionsspektrometrie
EP0548027A2 (de) Einrichtung zur spektralphotometrischen Analyse
DE19848120C2 (de) Einrichtung zur Messung der Strahlungsabsorption von Gasen
EP0473940B1 (de) Fotometeranordnung mit Streulichtfalle
DE961219C (de) Vorrichtung fuer die gleichzeitige Registrierung der Brechungsindexfunktion und ihrer Ableitung in Messzellen mit geschichteten Loesungen
EP3060901A2 (de) Optochemischer sensor
DE19920184A1 (de) Verfahren für die gleichzeitige Erfassung von diffuser und specularer Reflexion von Proben, insbesondere undurchsichtiger Proben, sowie Reflektanz-Meßsonde
DE2560064C3 (de) Verfahren zur optischen Messung von Blutgasen
DE2622547C3 (de) Vorrichtung zur fluorometrischen Bestimmung von Aminosäuren
DE2328193C3 (de) Vorrichtung zur Aufteilung des Lichts einer Lichtquelle in mindestens zwei Teilstrahlen mit zueinander konstantem Intensitätsverhältnis

Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee