DE3407654C2 - Verwendung von Benzamid-Derivaten - Google Patents

Verwendung von Benzamid-Derivaten

Info

Publication number
DE3407654C2
DE3407654C2 DE3407654A DE3407654A DE3407654C2 DE 3407654 C2 DE3407654 C2 DE 3407654C2 DE 3407654 A DE3407654 A DE 3407654A DE 3407654 A DE3407654 A DE 3407654A DE 3407654 C2 DE3407654 C2 DE 3407654C2
Authority
DE
Germany
Prior art keywords
aminoethyl
compounds
addition salts
acid addition
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3407654A
Other languages
German (de)
English (en)
Other versions
DE3407654A1 (de
Inventor
Mose Da Prada
Renato Joos
Emilio Kyburz
Pierre Charles Wyss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE3407654A1 publication Critical patent/DE3407654A1/de
Application granted granted Critical
Publication of DE3407654C2 publication Critical patent/DE3407654C2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE3407654A 1983-03-03 1984-03-01 Verwendung von Benzamid-Derivaten Expired - Fee Related DE3407654C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1150/83A CH653670A5 (de) 1983-03-03 1983-03-03 Benzamid-derivate.

Publications (2)

Publication Number Publication Date
DE3407654A1 DE3407654A1 (de) 1984-09-06
DE3407654C2 true DE3407654C2 (de) 1994-04-07

Family

ID=4203649

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3407654A Expired - Fee Related DE3407654C2 (de) 1983-03-03 1984-03-01 Verwendung von Benzamid-Derivaten

Country Status (28)

Country Link
JP (1) JPS59167552A (da)
KR (1) KR910008202B1 (da)
AR (1) AR243155A1 (da)
AT (1) AT390948B (da)
AU (2) AU570431B2 (da)
BE (1) BE899059A (da)
CA (1) CA1252794A (da)
CH (1) CH653670A5 (da)
DE (1) DE3407654C2 (da)
DK (1) DK166382C (da)
ES (3) ES530230A0 (da)
FI (1) FI79297C (da)
FR (1) FR2541996B1 (da)
GB (1) GB2135998B (da)
GR (1) GR81866B (da)
HU (1) HU193556B (da)
IE (1) IE57004B1 (da)
IL (1) IL71078A (da)
IT (1) IT1173365B (da)
LU (1) LU85231A1 (da)
MC (1) MC1568A1 (da)
NL (1) NL8400459A (da)
NO (1) NO165999C (da)
NZ (1) NZ207272A (da)
PH (1) PH19623A (da)
PT (1) PT78187B (da)
SE (1) SE466447B (da)
ZA (1) ZA841394B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1261335A (en) * 1984-08-29 1989-09-26 Hoffmann-La Roche Limited/Hoffmann-La Roche Limitee Ethylenediamine monoamide derivatives
US4772630A (en) * 1984-11-23 1988-09-20 Ciba-Geigy Corp. Benzamides and their salts
NZ219974A (en) * 1986-04-22 1989-08-29 Goedecke Ag N-(2'-aminophenyl)-benzamide derivatives, process for their preparation and their use in the control of neoplastic diseases
FR2642972B1 (fr) * 1989-02-14 1994-08-05 Inst Nat Sante Rech Med Agents pour le diagnostic et le traitement des melanomes, derives halogenes aromatiques utilisables comme de tels agents et leur preparation
WO2014155184A1 (en) * 2013-03-28 2014-10-02 Rhenovia Pharma Treatment for parkinson's disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342679A (en) * 1967-09-19 Parts by weight of acid chloride to react with parts of amine in
FR6557M (da) * 1967-06-20 1968-12-23 Ile De France
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
GB1520584A (en) * 1975-04-02 1978-08-09 Yamanouchi Pharma Co Ltd 2 - alkoxy - 5 substituted benzamide derivatives and their use in pharmaceutical compositions
DE2616486A1 (de) * 1976-04-14 1977-11-03 Basf Ag Farbstoffe der perylentetracarbonsaeurediimidreihe
CA1206964A (en) * 1980-11-12 1986-07-02 Nobuo Shinma Tetra-substituted benzene derivatives
DE3200258A1 (de) * 1982-01-07 1983-07-21 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Substituierte 1-benzoyl-2-phenylimino-imidazolidine, deren saeureadditionssalze, verfahren zu deren herstellung und diese enthaltende arzneimittel
IL69997A0 (en) * 1983-01-03 1984-01-31 Miles Lab Procainamide and n-acetylprocainamide immunogens,antibodies prepared therefrom,labeled conjugates,and the use of such antibodies and labeled conjugates in immunoassays
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides

Also Published As

Publication number Publication date
GB2135998B (en) 1986-09-24
SE8401190L (sv) 1984-09-04
AU570431B2 (en) 1988-03-17
DK166382B (da) 1993-05-10
ES8504680A1 (es) 1985-05-01
CH653670A5 (de) 1986-01-15
FI79297C (fi) 1989-12-11
ES530230A0 (es) 1985-05-01
AU609758B2 (en) 1991-05-09
JPS59167552A (ja) 1984-09-21
FI840734A (fi) 1984-09-04
IE840512L (en) 1984-09-03
NO165999C (no) 1991-05-15
GR81866B (da) 1984-12-12
FR2541996B1 (fr) 1987-12-11
PT78187B (en) 1986-08-05
ES8506601A1 (es) 1985-08-16
IT1173365B (it) 1987-06-24
HU193556B (en) 1987-10-28
DK147584D0 (da) 1984-02-29
FI79297B (fi) 1989-08-31
NO840797L (no) 1984-09-04
PH19623A (da) 1986-06-04
SE466447B (sv) 1992-02-17
NO165999B (no) 1991-02-04
AT390948B (de) 1990-07-25
AU2506684A (en) 1984-09-06
ATA72484A (de) 1990-01-15
ES8506600A1 (es) 1985-08-16
CA1252794A (en) 1989-04-18
FI840734A0 (fi) 1984-02-22
ES537046A0 (es) 1985-08-16
IL71078A (en) 1987-12-31
DE3407654A1 (de) 1984-09-06
IE57004B1 (en) 1992-03-11
NZ207272A (en) 1987-07-31
NL8400459A (nl) 1984-10-01
ZA841394B (en) 1985-06-26
MC1568A1 (fr) 1985-02-04
ES537045A0 (es) 1985-08-16
DK166382C (da) 1993-09-27
LU85231A1 (de) 1985-09-12
GB8405486D0 (en) 1984-04-04
IT8419778A0 (it) 1984-02-23
GB2135998A (en) 1984-09-12
PT78187A (en) 1984-04-01
KR910008202B1 (ko) 1991-10-11
IL71078A0 (en) 1984-05-31
AU8307987A (en) 1988-06-16
SE8401190D0 (sv) 1984-03-02
AR243155A1 (es) 1993-07-30
KR840009077A (ko) 1984-12-24
JPH0430389B2 (da) 1992-05-21
BE899059A (fr) 1984-09-03
FR2541996A1 (fr) 1984-09-07
DK147584A (da) 1984-09-04

Similar Documents

Publication Publication Date Title
DE1964516C3 (de) 1-Substituierte 3-Propionyl-anilinopyrrolidine, Verfahren zu ihrer Herstellung und Arzneimittel
DE2558501C2 (da)
DE1643262C3 (de) i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3530046A1 (de) Aethylendiaminmonoamid-derivate
DE2502993A1 (de) Amine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2818672A1 (de) Alpha-(1-r-3-azetidinyl)-alpha- phenyl-alpha-substituierte-acetamide oder -acetonitrile, verfahren zu ihrer herstellung und verwendung zur behandlung von herzarrhythmien
DE3407654C2 (de) Verwendung von Benzamid-Derivaten
CH631700A5 (de) Verfahren zur herstellung von neuen substituierten diphenylsulfiden.
DE2930608C2 (de) Alkylthiophenoxyalkylamine, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE1940566B2 (de) 1- (2-Nitrilophenoxy)-2-hydroxy-3äthylaminopropan, Verfahren zu dessen Herstellung und diese enthaltende Arzneimittel
DE2817083A1 (de) Benzylisochinolin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate
DE2829471C2 (da)
DE3035688A1 (de) 2-amino-3-benzoyl-phenylacetamid-derivate, pharmazeutische zubereitungen, welche diese verbindungen enthalten und verfahren zu ihrer herstellung
CH637646A5 (de) Analgetisch wirksame triazindione, herstellungsverfahren und pharmazeutische zusammensetzungen.
DE1770331A1 (de) Verfahren zur Herstellung einer neuen heterocylischen Verbindung mit entzuendungshemmender Wirksamkeit
DE2616403A1 (de) Verfahren zur herstellung des diastereoisomeren a durch racemische trennung von 5 eckige klammer auf 1-hydroxy-2-(1-methyl-3-phenylpropylamino)-aethyl eckige klammer zu salicylamid sowie es enthaltende arzneimittel
DE1620295C3 (de) Isochinolo eckige Klammer auf 2,1-d eckige Klammer zu benzo eckige Klammer auf 1,4 eckige Klammer zu diazepin-6-one
DE3786187T2 (de) Chemische Verbindung.
CH635312A5 (de) Alpha-aryl-alpha,alpha-bis(omega-(disubstituierte amino)-alkyl)acetamide und deren saeureanlagerungssalze, verfahren zu ihrer herstellung sowie sie enthaltende arzneimittelzubereitungen.
CH641167A5 (en) N-Cyano-N'-(2-((4-methyl-5-imidazolyl)-methylthio)ethyl)-N''-alkyny l guanidines
DE2705949C2 (de) 4-(Benzoylamino)-piperidinderivate, ein Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
DE3004348C2 (da)
DE2127812C2 (de) 3-Methyl-7-phenyl-5H-pyrimido [1,2-a] [1,4] benzodiazepin-1-one und Verfahren zu deren Herstellung
DE2530613A1 (de) Aminderivate, verfahren zu deren herstellung und sie enthaltende arzneimittel
DD202692A5 (de) Verfahren zur herstellung neuer derivate des 2-amino-aethanols

Legal Events

Date Code Title Description
8101 Request for examination as to novelty
8105 Search report available
8127 New person/name/address of the applicant

Owner name: F. HOFFMANN-LA ROCHE AG, BASEL, CH

8128 New person/name/address of the agent

Representative=s name: LEDERER, F., DIPL.-CHEM. DR., 8000 MUENCHEN RIEDER

8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: LEDERER, F., DIPL.-CHEM. DR., 8000 MUENCHEN RIEDER

8125 Change of the main classification

Ipc: A61K 31/165

D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee