DE3405581C2 - - Google Patents

Info

Publication number
DE3405581C2
DE3405581C2 DE3405581A DE3405581A DE3405581C2 DE 3405581 C2 DE3405581 C2 DE 3405581C2 DE 3405581 A DE3405581 A DE 3405581A DE 3405581 A DE3405581 A DE 3405581A DE 3405581 C2 DE3405581 C2 DE 3405581C2
Authority
DE
Germany
Prior art keywords
coenzyme
carnitine
animals
treated
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3405581A
Other languages
German (de)
English (en)
Other versions
DE3405581A1 (de
Inventor
Alberto Mailand/Milano It Bertelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of DE3405581A1 publication Critical patent/DE3405581A1/de
Application granted granted Critical
Publication of DE3405581C2 publication Critical patent/DE3405581C2/de
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE19843405581 1983-02-16 1984-02-16 Pharmazeutische zusammensetzung mit metabolischer und energetischer wirksamkeit zur verwendung in der herz- und gefaesstherapie Granted DE3405581A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH858/83A CH655005A5 (it) 1983-02-16 1983-02-16 Composizione farmaceutica ad azione metabolica ed energetica utilizzabile in terapia cardiaca e vascolare.

Publications (2)

Publication Number Publication Date
DE3405581A1 DE3405581A1 (de) 1984-10-18
DE3405581C2 true DE3405581C2 (cg-RX-API-DMAC7.html) 1992-10-22

Family

ID=4196830

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843405581 Granted DE3405581A1 (de) 1983-02-16 1984-02-16 Pharmazeutische zusammensetzung mit metabolischer und energetischer wirksamkeit zur verwendung in der herz- und gefaesstherapie

Country Status (11)

Country Link
US (1) US4599232A (cg-RX-API-DMAC7.html)
JP (1) JPS59186914A (cg-RX-API-DMAC7.html)
BE (1) BE898918A (cg-RX-API-DMAC7.html)
CH (1) CH655005A5 (cg-RX-API-DMAC7.html)
DE (1) DE3405581A1 (cg-RX-API-DMAC7.html)
DK (1) DK165167C (cg-RX-API-DMAC7.html)
FR (1) FR2543827B1 (cg-RX-API-DMAC7.html)
GB (1) GB2137088B (cg-RX-API-DMAC7.html)
IT (1) IT1170235B (cg-RX-API-DMAC7.html)
NL (1) NL192778C (cg-RX-API-DMAC7.html)
SE (1) SE457143B (cg-RX-API-DMAC7.html)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209519B (it) * 1984-04-10 1989-08-30 Poli Ind Chimica Spa Composti ad attivita'cardiotrofica.
CH662505A5 (it) * 1985-04-30 1987-10-15 Seuref Ag Composizioni farmaceutiche ad azione protettiva vascolare.
CH670763A5 (cg-RX-API-DMAC7.html) * 1985-08-02 1989-07-14 Seuref Ag
CH666183A5 (it) * 1985-08-06 1988-07-15 Seuref Ag Composizione farmaceutica ad azione protettiva cardiaca e metabolica sul metabolismo energetico muscolare.
IT1184655B (it) * 1985-10-14 1987-10-28 Sigma Tau Ind Farmaceuti Imiego di acetil l-carnitina nel trattamento terapeutico degli stati di shock
SE8703321D0 (sv) * 1987-08-27 1987-08-27 Sockerbolaget Ab Kostforsterkning
JPH02188523A (ja) * 1989-01-13 1990-07-24 M S C:Kk 睡眠時無呼吸症治療薬
GB8907276D0 (en) * 1989-03-31 1989-05-17 Therapy Advisory Services Limi Health supplement
AT393954B (de) * 1990-02-28 1992-01-10 Bock Orthopaed Ind Verfahren und vorrichtung zur bestimmung von gebrauchseigenschaften eines prothesenschaftes
IT1254314B (it) * 1992-03-27 1995-09-14 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche conyenenti l-carnitina e acil- carnitine inassociazione con ace-inibitori per il trattamento di patologie cardiovascolari.
WO1993024650A1 (en) * 1992-05-28 1993-12-09 Monash University Therapeutic compositions
DE4335454A1 (de) * 1993-10-19 1995-04-20 Schleicher Peter Geriatrikum
US5707971A (en) * 1995-06-07 1998-01-13 Life Resuscitation Technologies, Inc. Modulation of glycolytic ATP production
DK0969744T3 (da) * 1997-03-27 2003-06-23 Khursheed N Jeejeebhoy Kosttilskud til forbedringer af celleenergetik
US6080788A (en) * 1997-03-27 2000-06-27 Sole; Michael J. Composition for improvement of cellular nutrition and mitochondrial energetics
IT1291127B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica
US5973004A (en) * 1997-04-04 1999-10-26 Howard; James R. L-carnitine, acetyl-L-carnitine, and pantothenic acid or ubiquinone, combined for prevention and treatment of syndromes related to ineffective energy metabolism
US5889055A (en) * 1997-04-04 1999-03-30 Howard; James R. L-carnitine and acetyl-L-carnitine combined for prevention and treatment of syndromes related to diseases of energy metabolism
US5916912A (en) * 1997-06-16 1999-06-29 The Regents Of The University Of California Dietary composition for enhancing metabolism and alleviating oxidative stress
US7371415B1 (en) 1998-04-03 2008-05-13 The Daily Wellness Company Method and composition for improving sexual fitness
US20050196470A9 (en) * 1998-04-03 2005-09-08 Wuh Hank C Method and composition for enhancing sexual desire
WO1999051252A1 (en) * 1998-04-03 1999-10-14 The Daily Wellness Company Compositions comprising l-arginine, ginseng and gingko biloba for enhancing blood circulation
IT1299266B1 (it) 1998-05-15 2000-02-29 Sigma Tau Ind Farmaceuti Inibitori reversibili della carnitina palmitoil trasferasi
US6616942B1 (en) 1999-03-29 2003-09-09 Soft Gel Technologies, Inc. Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing
US6479069B1 (en) 1999-09-23 2002-11-12 Juvenon, Inc. Nutritional supplement for increased energy and stamina
US6562869B1 (en) 1999-09-23 2003-05-13 Juvenon, Inc. Nutritional supplement for increased energy and stamina
US20070072927A1 (en) * 1999-09-23 2007-03-29 Vita Joseph A Nutritional supplement for increased energy and stamina
US6335361B1 (en) 1999-11-03 2002-01-01 Juvenon Inc. Method of treating benign forgetfulness
US8753675B1 (en) 2000-01-20 2014-06-17 Raj K. Chopra Reduced form of Coenzyme Q in high bioavailability stable dosage forms and related applications
US6740338B1 (en) 2000-01-20 2004-05-25 Raj K. Chopra Reduced form of Cenzyme Q in high bioavailability stable oral dosage form
US20010043983A1 (en) * 2000-01-25 2001-11-22 Hamilton Nathan D. Nutritional supplements for aged pets
DE10036798A1 (de) * 2000-07-28 2002-02-07 Beiersdorf Ag Mittel zur Behandlung der Haare und der Kopfhaut
US6441050B1 (en) 2000-08-29 2002-08-27 Raj K. Chopra Palatable oral coenzyme Q liquid
US6497885B2 (en) 2000-12-22 2002-12-24 The Daily Wellness Company Method and composition for improving fertility health in female and male animals and humans
US6989164B2 (en) 2000-12-22 2006-01-24 The Daily Wellness Company Method and composition for improving male fertility health
US6579866B2 (en) 2000-12-28 2003-06-17 Mccleary Larry Composition and method for modulating nutrient partitioning
US20060062864A1 (en) * 2000-12-28 2006-03-23 Mccleary Edward L Weight loss composition and method
US20040043013A1 (en) 2000-12-28 2004-03-04 Mccleary Edward Larry Metabolic uncoupling therapy
KR100685696B1 (ko) * 2001-05-10 2007-02-23 카네카 코포레이션 활성 성분으로 조효소 ｑ를 함유하는 경점막 투여용 조성물
EP1407782A4 (en) * 2001-06-28 2004-10-20 Takeda Chemical Industries Ltd AGENTS FOR PREVENTION / TREATMENT OF FUNCTIONAL ORGANIC DISEASES AND ORGANIC DYSFUNCTION
US8703209B2 (en) * 2003-06-17 2014-04-22 Edward Larry McCleary Composition and method for modulating hydrogen ion physiology
EP1643863A2 (en) * 2003-07-10 2006-04-12 Carl A. Forest Foods, beverages, condiments, spices and salad dressings with specialized supplements
US20080089877A1 (en) * 2003-08-14 2008-04-17 Udell Ronald G Super Absorption Coenzyme Q10
WO2005032278A1 (en) 2003-09-29 2005-04-14 Soft Gel Technologies, Inc. SOLUBILIZED CoQ-10
US7169385B2 (en) * 2003-09-29 2007-01-30 Ronald G. Udell Solubilized CoQ-10 and carnitine
US8124072B2 (en) 2003-09-29 2012-02-28 Soft Gel Technologies, Inc. Solubilized CoQ-10
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
US20070225355A1 (en) * 2004-06-29 2007-09-27 Elixirin Corporation Dietary Compositions for Enhancing Metabolism and Reducing Reactive Oxygen Species
MX2007015006A (es) * 2005-06-01 2008-03-18 Edison Pharmaceuticals Inc Sustancias terapeuticas activas redox para el tratamiento de enfermedades mitocondriales y otras condiciones o modulacion de biomarcadores de energia.
US20050249803A1 (en) * 2005-06-03 2005-11-10 Udell Ronald G Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
US7887852B2 (en) * 2005-06-03 2011-02-15 Soft Gel Technologies, Inc. Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols
ES2823728T3 (es) * 2005-09-15 2021-05-10 Ptc Therapeutics Inc Variantes de cola de agentes terapéuticos con actividad redox para el tratamiento de enfermedades mitocondriales y otras afecciones y la modulación de biomarcadores de energía
US20100022629A1 (en) * 2006-01-13 2010-01-28 Elixirin Dietary Methods and Compositions for Enhancing Metabolism and Reducing Reactive Oxygen Species
JP5374162B2 (ja) 2006-02-22 2013-12-25 エジソン ファーマシューティカルズ， インコーポレイテッド ミトコンドリア病および他の症状の処置のためのレドックス活性化治療の側鎖変異体およびエネルギーバイオマーカーの調節
US20080020022A1 (en) * 2006-06-05 2008-01-24 Udell Ronald G Chewable co-enzyme q-10 capsule
ATE547743T1 (de) * 2007-03-14 2012-03-15 Fujifilm Corp Lichtempfindliche zusammensetzung und herstellungsverfahren für ein gehärtetes reliefmuster
US8343541B2 (en) 2007-03-15 2013-01-01 Soft Gel Technologies, Inc. Ubiquinol and alpha lipoic acid compositions
ES2306610B1 (es) * 2007-04-16 2009-09-11 Universidad De Sevilla Uso de la l-carnitina para el tratamiento de la hipertension arterial.
TW200918096A (en) * 2007-06-22 2009-05-01 Kaneka Corp Composition comprising bioactive substance
TW200916090A (en) * 2007-06-22 2009-04-16 Kaneka Corp Composition comprising coenzyme Q10
US20110123505A1 (en) * 2007-08-22 2011-05-26 Kaneka Corporation Method of producing reduced coenzyme q10 and method of stabilizing the same
CN101951930A (zh) * 2008-02-19 2011-01-19 阿奈斯特药品株式会社 对身体功能的恢复有用的口服或经肠组合物
MX363223B (es) 2008-09-10 2019-03-15 Bioelectron Tech Corp Tratamiento de trastornos generalizados del desarrollo con terapeuticos con actividad redox.
CA3008849A1 (en) 2015-12-17 2017-06-22 Bioelectron Technology Corporation Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2903558C2 (de) * 1978-02-03 1994-09-01 Sigma Tau Ind Farmaceuti Verwendung von L-Carnitin
IT1206954B (it) * 1979-02-12 1989-05-17 Sigma Tau Ind Farmaceuti Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche
US4346107A (en) * 1979-02-12 1982-08-24 Claudio Cavazza Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism
IT1142934B (it) * 1981-11-06 1986-10-15 Sigma Tau Ind Farmaceuti Uso della carnitina e delle acilcarnitine inferiori nel trattamento terapeutico della patologia delle vene

Also Published As

Publication number Publication date
SE457143B (sv) 1988-12-05
NL192778C (nl) 1998-02-03
FR2543827A1 (fr) 1984-10-12
DE3405581A1 (de) 1984-10-18
GB2137088B (en) 1986-02-05
US4599232A (en) 1986-07-08
GB2137088A (en) 1984-10-03
DK165167B (da) 1992-10-19
DK165167C (da) 1993-03-01
GB8403668D0 (en) 1984-03-14
IT1170235B (it) 1987-06-03
JPS59186914A (ja) 1984-10-23
DK72284A (da) 1984-08-17
NL192778B (nl) 1997-10-01
DK72284D0 (da) 1984-02-16
SE8400851D0 (sv) 1984-02-16
SE8400851L (sv) 1984-08-17
NL8400488A (nl) 1984-09-17
FR2543827B1 (fr) 1987-06-12
BE898918A (nl) 1984-08-16
JPH027572B2 (cg-RX-API-DMAC7.html) 1990-02-19
IT8323559A0 (it) 1983-10-31
CH655005A5 (it) 1986-03-27

Similar Documents

Publication Publication Date Title
DE3405581C2 (cg-RX-API-DMAC7.html)
DE69909775T2 (de) Neue fettanaloge zur behandlung von diabetes
DE60212786T2 (de) Verwendung mehrfach ungesättigter Fettsäuren zur primären Prävention kardiovaskulärer Ereignisse
DE69618158T2 (de) Pharmazeutische Zusammensetzung enthaltend ein Alkanoyl-L-Carnitin in Kombination mit einer polyungesättigten Fettsäure der Omega-3-Serie zur Verhütung und Behandlung von Störungen des Fettstoffwechsels
DE69327468T2 (de) Verfahren zur reduktion der blutspiegel von gesamtcholesterin und ldl-cholesterin
DE2817358C2 (cg-RX-API-DMAC7.html)
DE69022678T2 (de) S(+)-Ibuprofen-L-Aminosäure und S(+)-Ibuprofen-D-Aminosäure als Analgetika mit grösserem pharmakologischem Potential.
DE2621214B2 (de) Verwendung von Stabilisatoren in Arzneimitteln mit Fumarsäuremonoäthylester und dessen Mineralsalzen
DE10164711A1 (de) Verwendung von Zuckerphosphaten, Zuckerphosphatanalogen, Aminosäuren und/oder Aminosäureanalogen zur Modulation des Glycolyse-Enzym-Komplexes, des Malat Aspartat Shuttles und/oder der Transaminasen
DE3119460A1 (de) Pharmazeutische zusammensetzung aus l-karnitin und/oder l-acylkarnitin und verwendung der zusammensetzung gegen diabetes mellitus bei jugendlichen
DE3200016A1 (de) Oral oder parenteral berabreichbare arzneimittelzubereitung mit einem gehalt an (gamma)-butyrobetain zur behandlung von syndromen, hervorgerufen durch l-carnitinmangel
DE3838716C2 (cg-RX-API-DMAC7.html)
DE2514335C3 (de) Oral zu verabreichendes Arzneimittel mit Antiplasmin-Inhibitorwirkung
DE60313886T2 (de) Zusammensetzung von einem PPAR-alpha Agonisten und Metformin zur Behandlung von Obesitas
DE3000139C2 (de) Verwendung von Glyzerinphosphorylderivaten zur Behandlung der Dislipämie, der akuten, subakuten oder chronischen Hepatitis und der Steatose
DE1815808A1 (de) Benzolderivate
DE69330842T2 (de) Verwendung von Monosialogangliosid GMl oder von N-Dichlor-Acetyl-lyso-GMl zur Vorbeugung oder zur Umkehrung der von einer Langzeitbehandlung mit L-DOPA bei der Therapie von Morbus Parkinson induzierten neuronale Degeneration
DE3035494A1 (de) Carnitin enthaltendes arzneimittel zur behandlung von hyperlipidaemie und hyperlipoproteinaemie, sowie verwendung von carnitin zur herstellung eines solchen arzneimittels
DE69407684T2 (de) Verwendung von L-Carnitine oder Acyl-L-Carnitinen und Valproat zur Behandlung von Anfallserkrankungen
DE3609005A1 (de) Pharmazeutische zusammensetzungen mit metabolischer aktivitaet
EP0472033B1 (de) 3,5-Diiod-L-Thyronin zur TSH-Suppression und Behandlung von Struma
EP0043548B1 (de) Salz aus Furosemid oder Piretanid als Säurekomponente und Penbutolol als Basenkomponente sowie Arzneimittel, das beide Komponenten enthält
CH366523A (de) Verfahren zur Herstellung der neuen 1,3,4,6- und 1,3,4,5-Tetranicotinoyl-fructose
DE3625459C2 (cg-RX-API-DMAC7.html)
DE1667903C3 (de) Verwendung von Cysteinderivaten zur Herstellung von per oral verabreichbaren Mitteln zur Bekämpfung der Seborrhoe

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: HOFFMANN * EITLE, 81925 MUENCHEN