DE3205149C2 - - Google Patents

Info

Publication number
DE3205149C2
DE3205149C2 DE3205149A DE3205149A DE3205149C2 DE 3205149 C2 DE3205149 C2 DE 3205149C2 DE 3205149 A DE3205149 A DE 3205149A DE 3205149 A DE3205149 A DE 3205149A DE 3205149 C2 DE3205149 C2 DE 3205149C2
Authority
DE
Germany
Prior art keywords
propanediol
compound
theophyllin
phenylpiperazin
piperazin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3205149A
Other languages
German (de)
English (en)
Other versions
DE3205149A1 (de
Inventor
Vittorio Pestellini
Mario Florenz/Firenze It Ghelardoni
Danilo Altopascio Lucca It Giannotti
Alberto Meli
Carlo Alberto Florenz/Firenze It Maggi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Menarini SAS
Original Assignee
Menarini SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini SAS filed Critical Menarini SAS
Publication of DE3205149A1 publication Critical patent/DE3205149A1/de
Application granted granted Critical
Publication of DE3205149C2 publication Critical patent/DE3205149C2/de
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE19823205149 1981-02-25 1982-02-13 3-(4-phenyl-1-piperazinio-1-yl)-1,2-propandiol-3-(theophyllin-7-yl)-propansulfonat, verfahren zu seiner herstellung und es enthaltende arzneimittel Granted DE3205149A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8109343A IT1210639B (it) 1981-02-25 1981-02-25 Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazione

Publications (2)

Publication Number Publication Date
DE3205149A1 DE3205149A1 (de) 1982-11-11
DE3205149C2 true DE3205149C2 (US20090192370A1-20090730-C00001.png) 1991-04-18

Family

ID=11128724

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19823205149 Granted DE3205149A1 (de) 1981-02-25 1982-02-13 3-(4-phenyl-1-piperazinio-1-yl)-1,2-propandiol-3-(theophyllin-7-yl)-propansulfonat, verfahren zu seiner herstellung und es enthaltende arzneimittel

Country Status (18)

Country Link
US (1) US4372958A (US20090192370A1-20090730-C00001.png)
JP (1) JPS57188589A (US20090192370A1-20090730-C00001.png)
AT (1) AT380881B (US20090192370A1-20090730-C00001.png)
BE (1) BE892271A (US20090192370A1-20090730-C00001.png)
CA (1) CA1192549A (US20090192370A1-20090730-C00001.png)
CH (1) CH651043A5 (US20090192370A1-20090730-C00001.png)
DE (1) DE3205149A1 (US20090192370A1-20090730-C00001.png)
DK (1) DK148687C (US20090192370A1-20090730-C00001.png)
ES (1) ES8302680A1 (US20090192370A1-20090730-C00001.png)
FR (1) FR2500455A1 (US20090192370A1-20090730-C00001.png)
GB (1) GB2093445B (US20090192370A1-20090730-C00001.png)
GR (1) GR76060B (US20090192370A1-20090730-C00001.png)
IT (1) IT1210639B (US20090192370A1-20090730-C00001.png)
LU (1) LU83962A1 (US20090192370A1-20090730-C00001.png)
NL (1) NL8200746A (US20090192370A1-20090730-C00001.png)
PT (1) PT74463B (US20090192370A1-20090730-C00001.png)
SE (1) SE440503B (US20090192370A1-20090730-C00001.png)
YU (1) YU44007B (US20090192370A1-20090730-C00001.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1203721B (it) * 1983-12-29 1989-02-23 Dompe Farmaceutici Spa Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono
IT1217950B (it) * 1988-06-28 1990-03-30 Dott Formenti Ind Chimica E Fa Sali di (r,s) 3 (4 fenil 1 piperazinil) 1,2 propandtolo
IT1231158B (it) * 1989-07-20 1991-11-19 Dompe Farmaceutici Spa Procedimento per la risoluzione ottica della dropropizina.
DE3938123A1 (de) * 1989-11-16 1991-05-23 Diehl Gmbh & Co Treibladungsanzuender
IT1318651B1 (it) * 2000-07-28 2003-08-27 Dompe Spa Sintesi di (+-)1,3-diossolani e loro risoluzione ottica.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3163649A (en) * 1964-12-29 Substituteb phenyl-piperazine
GB938646A (en) * 1961-03-16 1963-10-02 Henri Morren New piperazine derivatives
FR1384693A (fr) * 1963-10-08 1965-01-08 Electrochimie Soc Procédé de préparation d'esters méthallyliques
FR1554628A (US20090192370A1-20090730-C00001.png) * 1967-05-23 1969-01-24

Also Published As

Publication number Publication date
SE8201184L (sv) 1982-08-26
DK148687B (da) 1985-09-02
DK79982A (da) 1982-08-26
LU83962A1 (fr) 1982-07-08
FR2500455B1 (US20090192370A1-20090730-C00001.png) 1984-04-27
IT8109343A0 (it) 1981-02-25
US4372958A (en) 1983-02-08
CH651043A5 (it) 1985-08-30
DE3205149A1 (de) 1982-11-11
JPS57188589A (en) 1982-11-19
PT74463A (en) 1982-03-01
NL8200746A (nl) 1982-09-16
SE440503B (sv) 1985-08-05
GB2093445B (en) 1985-02-27
FR2500455A1 (fr) 1982-08-27
ATA59982A (de) 1985-12-15
IT1210639B (it) 1989-09-14
DK148687C (da) 1986-04-28
ES509850A0 (es) 1983-02-01
AT380881B (de) 1986-07-25
GB2093445A (en) 1982-09-02
PT74463B (en) 1983-08-24
GR76060B (US20090192370A1-20090730-C00001.png) 1984-08-03
ES8302680A1 (es) 1983-02-01
YU41282A (en) 1987-10-31
BE892271A (fr) 1982-06-16
CA1192549A (en) 1985-08-27
JPH0333715B2 (US20090192370A1-20090730-C00001.png) 1991-05-20
YU44007B (en) 1990-02-28

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee