DE3205018A1 - Bifidobakterien vermehrendes mittel - Google Patents
Bifidobakterien vermehrendes mittelInfo
- Publication number
- DE3205018A1 DE3205018A1 DE19823205018 DE3205018A DE3205018A1 DE 3205018 A1 DE3205018 A1 DE 3205018A1 DE 19823205018 DE19823205018 DE 19823205018 DE 3205018 A DE3205018 A DE 3205018A DE 3205018 A1 DE3205018 A1 DE 3205018A1
- Authority
- DE
- Germany
- Prior art keywords
- bifidobacteria
- cyclodextrin
- bacteria
- administration
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/16—Cyclodextrin; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- General Preparation And Processing Of Foods (AREA)
Description
• | Anzahl der Glucoseeinheiten |
ii-Cyclodextr in | 14.5 | ß-Cyclrodextrin | •y*-Cyclod-extr in |
Molekulargewicht | 6 | 7 | 8 | ||
Höhlungsdurch messer, nm |
973 | 1135 | 129 7' | ||
Höhlungs tiefe, nm · · |
0,5 - 0,6 | 0,7 - 0,8 | 0,9 - 1,0 | ||
Kristali- form 1) |
0,7 - 0,8 | 0,7 - 0,8 | 0,7 - 0,8 ' | ||
Optische 2) Drehung |
nadeiförmig | prismatisch | prismatisch | ||
Löslichkeit ■ in Wasser, (q/100 ml bei 25°C) |
+150.5° | +162.5° | +177.4° · | ||
1.85 | • 23.2 |
Verabrei- | Tier- | "4 | α-Cyclo dextrin |
LD50 | (g/kg) | γ-c^cio- dextri-n |
ehungsweg | >12.5 | ß-Cyclo dextrin |
>12.5 | |||
Maus | ί | >12·.5 | ... >12.5 | >12.5 | ||
Qral ' | O | >12 | >12.5 | >12 | ||
Ratte | ί | >12 | >12 | >12 | ||
> 0.9- | • >12 | >0.9 . | ||||
subkutan . | Maus | ■t | > 0.9. | > 0.9 | > 0.9 | |
> 1.5 ". | > 0.9 | > 1.5 | ||||
Ratte | ί | > 1.5 | > 1.5 | ■ >: 1.5 | ||
> 0.9 | > 1.5 | > 0.9 | ||||
intraperi- | Maus | -.4; | > 0.9 | > 0.9 | > 0.9 | |
toneal | Ratte | > ■ 1. 2 | > 0.9 | > 1.2 | ||
> 1.2 | > 1.2 | > 1.2 | ||||
> 1.2 | ||||||
■'.. ■■"-."..■■.-. -
Bakterienart | Auszählung der Bakterien |
lebensfähigen | 6.5 χ | ίο7' | Vermehrung, B/A |
.00 |
vor(A) 7 Tage nach(B) der Verabreichung |
8.8 χ | 108 | .98' | |||
Bifidobakterien | 5.4.x ίο5: | 8.4 χ | ίο8 | 120 | .45 | |
IJactobacilli | 8.8 χ ΙΟ8 | S. 0 χ | 106 | 1 | ||
Bacteroides sp. | 8.6 χ 108 | 0 | ||||
Escherichia coli | 6.2 χ 106 | 1 | ||||
■ Bakterienart | Auszählung der 1) |
lebensfähigen | 1.8 | X | ίο8 | Vermehrung, B/A |
47 |
vor (A) 7 Tage nach (B) der Verabreichung |
2.2 | X | ίο9' | 06 | |||
Bifidobakterien | 1.3 x 105 | 3.7 | X | 108 | 1385 | 45 | |
Lactobacilli | 1.5 x 109 | 5.8 | X | 106 | 1. | ||
Bacteroides sp. | 3.5 χ 10S | 1. | |||||
Escherichia coli | 4.0 χ ΙΟ6 | ; ι. | |||||
Bakterienart | Auszählung.der lebensfähigen Bakterien |
Vermehrung, ß/A |
Bifidobakterien Lactobacilli Bacteroides sp. Escherichia coli |
vor (A) 7 Tage nach (B) der Verabreichung |
90 0.7 8. 3.0 0 0.93 |
2.0 χ 104 1.8 x 106 9.0 χ 108 ' .7.0 x 108 .1.0 χ 108 3.0 χ 108 7.5 χ 106 7.0 χ 106 |
Bakterienart | Auszählung,der _ , , T) |
lebensfähigen | X | 105 | Ί. 6 | X | 105 | Vermehrung, B/A |
. Bifidobakterien | vor der |
(A) 7'Tage nach" (B) Verabreichung |
X | 108 | 6.0 | X | ίο8 · | ■-0.70- |
Lactobacilli | 2. | 3 | X | IQ8 | 8.0 | X | 10 8 | 1.20 |
Bac'teroides sp. | 5 | 0 | X | 106 | 7,2 | X | 106 | 2.50 |
Escherichia coli | 3 | 2 | 0.80 . | |||||
9 | 0 |
Claims (2)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56022620A JPS5830032B2 (ja) | 1981-02-18 | 1981-02-18 | ビフイダス菌の増殖剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3205018A1 true DE3205018A1 (de) | 1982-08-19 |
DE3205018C2 DE3205018C2 (de) | 1986-03-06 |
Family
ID=12087868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3205018A Expired DE3205018C2 (de) | 1981-02-18 | 1982-02-12 | Verwendung von Cyclodextrin als Bifidobakterien vermehrendes Mittel |
Country Status (8)
Country | Link |
---|---|
US (1) | US4451457A (de) |
JP (1) | JPS5830032B2 (de) |
AU (2) | AU556379B2 (de) |
CA (1) | CA1179265A (de) |
DE (1) | DE3205018C2 (de) |
FR (1) | FR2499854B1 (de) |
GB (1) | GB2092890B (de) |
IT (1) | IT1150191B (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU708107B2 (en) * | 1994-11-04 | 1999-07-29 | Commonwealth Scientific And Industrial Research Organisation | Method for treating animals |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2117222B (en) * | 1982-02-10 | 1985-10-09 | Boc Group Plc | Freezing a liquid |
JPS5920230A (ja) * | 1982-07-19 | 1984-02-01 | チバ−ガイギ−・アクチエンゲゼルシヤフト | ピルプロフエン含有薬剤 |
HU196128B (en) * | 1985-01-10 | 1988-10-28 | Chinoin Gyogyszer Es Vegyeszet | Process for production of compound substituating bile and forwarding digestion of fat |
JPS61271986A (ja) * | 1985-05-27 | 1986-12-02 | Agency Of Ind Science & Technol | リンパ系細胞用培地 |
JPS61286318A (ja) * | 1985-06-13 | 1986-12-16 | Ichiro Shibauchi | 浴剤の製造方法 |
DE3609116A1 (de) * | 1986-03-14 | 1987-09-17 | Herbe Wirkstoffe Gmbh | Zubereitungen von gewuerzen oder drogen |
JPH07106143B2 (ja) * | 1987-04-09 | 1995-11-15 | 株式会社ヤクルト本社 | ビフイドバクテリウム菌含有粉末の製造法 |
JPH03104532U (de) * | 1990-02-15 | 1991-10-30 | ||
US7034013B2 (en) * | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
DE10203999A1 (de) * | 2002-02-01 | 2003-08-14 | Nutricia Nv | Cycloglycane |
CN100497594C (zh) * | 2006-05-12 | 2009-06-10 | 河北农业大学 | 一种高活性双歧杆菌干粉制剂的复合保护剂 |
WO2017195888A1 (ja) * | 2016-05-12 | 2017-11-16 | 国立大学法人 東京大学 | 固体培地での微生物の増殖能を増強する方法 |
CN111437248A (zh) * | 2020-03-17 | 2020-07-24 | 东华理工大学 | 一种益肠寿口服液及其制备方法与应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5443570B2 (de) * | 1972-10-27 | 1979-12-20 | ||
US3974274A (en) * | 1972-12-23 | 1976-08-10 | Tanabe Seiyaku Co., Ltd. | Process for preparing a cyclodextrin derivative |
JPS52108027A (en) * | 1976-03-09 | 1977-09-10 | Rikagaku Kenkyusho | Anticarcinogen |
HU176215B (en) * | 1978-01-27 | 1981-01-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing a cyclodextrin-indomethacin inclusion complex with a ratio of at about 2:1 |
HU176764B (en) * | 1978-05-23 | 1981-05-28 | Chinoin Gyogyszer Es Vegyeszet | Process for influencing the germination of plant seed and the growth of plants evolved therefrom by the application of dextrins |
HU176217B (en) * | 1978-11-20 | 1981-01-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing a cyclodextrin-chamomille inclusion complex and compositions containing thereof |
JPS55122709A (en) * | 1979-03-13 | 1980-09-20 | Asama Kasei Kk | Stench remover from mouth |
US4352793A (en) * | 1979-04-26 | 1982-10-05 | Sumitomo Chemical Company, Limited | Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin |
DE2947742C2 (de) * | 1979-11-27 | 1986-04-03 | Koch, Jürgen, Dr., 2000 Hamburg | Arzneimittel, enthaltend β-Cyclodextrin |
-
1981
- 1981-02-18 JP JP56022620A patent/JPS5830032B2/ja not_active Expired
-
1982
- 1982-02-10 CA CA000396000A patent/CA1179265A/en not_active Expired
- 1982-02-10 US US06/347,726 patent/US4451457A/en not_active Expired - Lifetime
- 1982-02-12 DE DE3205018A patent/DE3205018C2/de not_active Expired
- 1982-02-16 AU AU80569/82A patent/AU556379B2/en not_active Ceased
- 1982-02-17 IT IT19704/82A patent/IT1150191B/it active
- 1982-02-17 FR FR8202637A patent/FR2499854B1/fr not_active Expired
- 1982-02-17 GB GB8204627A patent/GB2092890B/en not_active Expired
-
1986
- 1986-09-09 AU AU62524/86A patent/AU574934B2/en not_active Ceased
Non-Patent Citations (7)
Title |
---|
Chem. Abstr. 87, 1977, 157099j * |
Chem. Abstr. 88, 1978, 27825v * |
Chem. Abstr. 88, 1978, 79103j * |
Chem. Abstr. 92, 1980, 185773f * |
Chem. Abstr. 92, 1980, 28556h * |
Chem. Abstr. 92, 1980, 64754b * |
Chem. Abstr. 93, 1980, 192036f * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU708107B2 (en) * | 1994-11-04 | 1999-07-29 | Commonwealth Scientific And Industrial Research Organisation | Method for treating animals |
Also Published As
Publication number | Publication date |
---|---|
GB2092890B (en) | 1986-01-02 |
AU8056982A (en) | 1982-08-26 |
IT8219704A0 (it) | 1982-02-17 |
DE3205018C2 (de) | 1986-03-06 |
US4451457A (en) | 1984-05-29 |
JPS5830032B2 (ja) | 1983-06-27 |
AU574934B2 (en) | 1988-07-14 |
AU556379B2 (en) | 1986-10-30 |
AU6252486A (en) | 1986-12-24 |
GB2092890A (en) | 1982-08-25 |
FR2499854A1 (fr) | 1982-08-20 |
CA1179265A (en) | 1984-12-11 |
FR2499854B1 (fr) | 1985-09-13 |
JPS57138385A (en) | 1982-08-26 |
IT1150191B (it) | 1986-12-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
OP8 | Request for examination as to paragraph 44 patent law | ||
8181 | Inventor (new situation) |
Free format text: YOSHIKUMI, CHIKAO, KUNITACHI, TOKYO, JP SAKURAI, KATSUO, HINO, TOKYO, JP OMURA, YOSHIO, FUNABASHI, CHIBA, JP NOHARA, MAYUMI, RYUGASAKI, IBARAKI, JP ANDO, TAKAO, NERIMA, TOKYO, JP MOTOKAWA, ISMA, HINO, TOKYO, JP |
|
8181 | Inventor (new situation) |
Free format text: YOSHIKUMI, CHIKAO, KUNITACHI, TOKYO, JP SAKURAI, KATSUO, HINO, TOKYO, JP OMURA, YOSHIO, FUNABASHI, CHIBA, JP NOHARA, MAYUMI, RYUGASAKI, IBARAKI, JP ANDO, TAKAO, NERIMA, TOKYO, JP MOTOKAWA, ISAMU, HINO, TOKYO, JP |
|
D2 | Grant after examination | ||
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Free format text: STOLBERG-WERNIGERODE, GRAF ZU, U., DIPL.-CHEM. DR.RER.NAT. SUCHANTKE, J., DIPL.-ING. HUBER, A., DIPL.-ING. KAMEKE, VON, A., DIPL.-CHEM. DR.RER.NAT., 2000 HAMBURG SCHULMEYER, K., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 2087 HASLOH |
|
8339 | Ceased/non-payment of the annual fee |