DE3132915A1 - 1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel - Google Patents
1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittelInfo
- Publication number
- DE3132915A1 DE3132915A1 DE19813132915 DE3132915A DE3132915A1 DE 3132915 A1 DE3132915 A1 DE 3132915A1 DE 19813132915 DE19813132915 DE 19813132915 DE 3132915 A DE3132915 A DE 3132915A DE 3132915 A1 DE3132915 A1 DE 3132915A1
- Authority
- DE
- Germany
- Prior art keywords
- halogen
- compounds
- hydrogen
- lower alkyl
- lower alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
- Luminescent Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813132915 DE3132915A1 (de) | 1981-08-20 | 1981-08-20 | 1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
ZA825381A ZA825381B (en) | 1981-08-20 | 1982-07-27 | 1,5-diphenylpyrazolin-3-one compounds method for preparing them,and pharmaceutical compositions containing these compounds |
PT75353A PT75353B (en) | 1981-08-20 | 1982-07-30 | Process for the preparation of 1,5-diphenylpyrazolin-3-ona compounds useful as medicines and of the intermediate products thereof |
EP82107193A EP0072960B1 (de) | 1981-08-20 | 1982-08-09 | 1,5-Diphenylpyrazolin-3-on-Verbindungen sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
DE8282107193T DE3279756D1 (en) | 1981-08-20 | 1982-08-09 | 1,5-diphenylpyrazolin-3-one compounds, process and intermediates for their preparation and medicines containing these compounds |
AT82107193T ATE43841T1 (de) | 1981-08-20 | 1982-08-09 | 1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel. |
CA000409072A CA1208643A (en) | 1981-08-20 | 1982-08-10 | 1,5-diphenyl-pyrazolin-3-one compounds, process and intermediates for preparation thereof and pharmaceutical compositions containing them |
DD82242578A DD202563A5 (de) | 1981-08-20 | 1982-08-17 | Verfahren zur herstellung von 1,5-diphenylpyrazolin-3-on-verbindungen |
GR69059A GR78228B (el) | 1981-08-20 | 1982-08-18 | |
PH27741A PH19107A (en) | 1981-08-20 | 1982-08-18 | 1,5-diphenylpyrazolin-3-one compounds,method for preparing them and pharmaceutical compositions containing these compounds |
GR69057A GR76272B (el) | 1981-08-20 | 1982-08-18 | |
HU822675A HU187572B (en) | 1981-08-20 | 1982-08-18 | Process for preparing 1,5-diphenyl-pyrazolin-3-one derivatives |
IL66580A IL66580A (en) | 1981-08-20 | 1982-08-19 | 1,5-diphenyl-2-piperazinylalkyl-pyrazolin-3-one compounds,their preparation and pharmaceutical compositions containing them |
AU87424/82A AU555215B2 (en) | 1981-08-20 | 1982-08-19 | 1,5-diphenylpyrazolin-3-one compounds |
NO822827A NO158185C (no) | 1981-08-20 | 1982-08-19 | Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1,5-difenylpyrazolin-3-on-forbindelser. |
US06/409,631 US4442102A (en) | 1981-08-20 | 1982-08-19 | 1,5-Diphenylpyrazolin-3-one compounds, process and intermediates for preparation thereof and pharmaceutical compositions containing same |
ES515107A ES8306143A1 (es) | 1981-08-20 | 1982-08-19 | "procedimiento para la preparacion de compuestos de 1,5-difenilpirazolin-3-ona". |
IE2002/82A IE55377B1 (en) | 1981-08-20 | 1982-08-19 | 1,5-diphenylpyrazolin-3-one compounds,method for preparing them,and pharmaceutical compositions containing these compounds |
FI822883A FI73673C (fi) | 1981-08-20 | 1982-08-19 | Foerfarande foer framstaellning av farmakologiskt vaerdefulla 1,5-difenylpyrazolin-3-on-foereningar. |
DK372382A DK149947C (da) | 1981-08-20 | 1982-08-19 | Analogifremgangsmaade til fremstilling af 1,5-diphenylpyrazolin-3-on-forbindelser eller syreadditionssalte deraf |
NZ201643A NZ201643A (en) | 1981-08-20 | 1982-08-19 | 1,5-diphenylpyrazolin-3-ones and pharmaceutical compositions |
JP57143479A JPS5839668A (ja) | 1981-08-20 | 1982-08-20 | 1,5−ジフエニルピラゾリン−3−オン化合物、その製造法及び該化合物を含有する、抗アレルギ−作用を有する医薬品 |
US06/564,399 US4515944A (en) | 1981-08-20 | 1983-12-22 | 1,5-Diphenyl-2-haloalkylpyrazolin-3-one intermediates |
CA000488742A CA1210763A (en) | 1981-08-20 | 1985-08-14 | 1,5-diphenyl-pyrazolin-3-one compounds, process and intermediates for preparation thereof and pharmaceutical compositions containing them |
DK181086A DK154834C (da) | 1981-08-20 | 1986-04-21 | 1,5-diphenylpyrazolin-derivater |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813132915 DE3132915A1 (de) | 1981-08-20 | 1981-08-20 | 1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3132915A1 true DE3132915A1 (de) | 1983-03-03 |
Family
ID=6139713
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19813132915 Withdrawn DE3132915A1 (de) | 1981-08-20 | 1981-08-20 | 1,5-diphenylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE8282107193T Expired DE3279756D1 (en) | 1981-08-20 | 1982-08-09 | 1,5-diphenylpyrazolin-3-one compounds, process and intermediates for their preparation and medicines containing these compounds |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8282107193T Expired DE3279756D1 (en) | 1981-08-20 | 1982-08-09 | 1,5-diphenylpyrazolin-3-one compounds, process and intermediates for their preparation and medicines containing these compounds |
Country Status (20)
Country | Link |
---|---|
US (2) | US4442102A (el) |
EP (1) | EP0072960B1 (el) |
JP (1) | JPS5839668A (el) |
AT (1) | ATE43841T1 (el) |
AU (1) | AU555215B2 (el) |
CA (1) | CA1208643A (el) |
DD (1) | DD202563A5 (el) |
DE (2) | DE3132915A1 (el) |
DK (1) | DK149947C (el) |
ES (1) | ES8306143A1 (el) |
FI (1) | FI73673C (el) |
GR (2) | GR76272B (el) |
HU (1) | HU187572B (el) |
IE (1) | IE55377B1 (el) |
IL (1) | IL66580A (el) |
NO (1) | NO158185C (el) |
NZ (1) | NZ201643A (el) |
PH (1) | PH19107A (el) |
PT (1) | PT75353B (el) |
ZA (1) | ZA825381B (el) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3442860A1 (de) * | 1984-11-24 | 1986-05-28 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 5-alkyl-1-phenyl-2-piperazinoalkylpyrazolin-3- on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
ES2281434T3 (es) * | 2000-08-14 | 2007-10-01 | Ortho-Mcneil Pharmaceutical, Inc. | Pirazoles sustituidos. |
US7589199B2 (en) | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
US20050256130A1 (en) * | 2002-06-12 | 2005-11-17 | Chemocentryx, Inc. | Substituted piperazines |
US7842693B2 (en) * | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
DE60328690D1 (de) * | 2002-06-12 | 2009-09-17 | Chemocentryx Inc | 1-aryl-4-substituierte piperazin-derivate zur verwendung als ccr1-antagonisten zur behandlung von entzündungen und immunerkrankungen |
WO2005084667A1 (en) * | 2004-03-03 | 2005-09-15 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
US7435831B2 (en) * | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
WO2011051958A1 (en) * | 2009-10-30 | 2011-05-05 | E.I. Du Pont De Nemours And Company | Fungicidal pyrazolones |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE74912C (el) * | ||||
DE66610C (de) * | FARBWERKE VORM. MEISTER LUCIUS & BRÜNING in Höchst a. M | Verfahren zur Darstellung von Oxaethylmethylphenylpyrazolon | ||
GB666578A (en) * | 1948-01-10 | 1952-02-13 | Luxema | Process for the preparation of derivatives of 1, 2, 3 substituted pyrazolones and derivatives obtained by this process |
US3169966A (en) * | 1961-01-24 | 1965-02-16 | Ciba Geigy Corp | Aminopyrazoles |
DE2824764A1 (de) * | 1978-06-06 | 1979-12-20 | Hoechst Ag | Neue pyridylpiperazinderivate und verfahren zu ihrer herstellung |
DE2828529A1 (de) * | 1978-06-29 | 1980-01-17 | Kali Chemie Pharma Gmbh | Neue 5-phenylpyrazol-derivate, verfahren zu deren herstellung und arzneimittel |
-
1981
- 1981-08-20 DE DE19813132915 patent/DE3132915A1/de not_active Withdrawn
-
1982
- 1982-07-27 ZA ZA825381A patent/ZA825381B/xx unknown
- 1982-07-30 PT PT75353A patent/PT75353B/pt not_active IP Right Cessation
- 1982-08-09 AT AT82107193T patent/ATE43841T1/de not_active IP Right Cessation
- 1982-08-09 EP EP82107193A patent/EP0072960B1/de not_active Expired
- 1982-08-09 DE DE8282107193T patent/DE3279756D1/de not_active Expired
- 1982-08-10 CA CA000409072A patent/CA1208643A/en not_active Expired
- 1982-08-17 DD DD82242578A patent/DD202563A5/de unknown
- 1982-08-18 PH PH27741A patent/PH19107A/en unknown
- 1982-08-18 GR GR69057A patent/GR76272B/el unknown
- 1982-08-18 HU HU822675A patent/HU187572B/hu not_active IP Right Cessation
- 1982-08-18 GR GR69059A patent/GR78228B/el unknown
- 1982-08-19 NO NO822827A patent/NO158185C/no unknown
- 1982-08-19 US US06/409,631 patent/US4442102A/en not_active Expired - Fee Related
- 1982-08-19 DK DK372382A patent/DK149947C/da not_active IP Right Cessation
- 1982-08-19 ES ES515107A patent/ES8306143A1/es not_active Expired
- 1982-08-19 AU AU87424/82A patent/AU555215B2/en not_active Ceased
- 1982-08-19 FI FI822883A patent/FI73673C/fi not_active IP Right Cessation
- 1982-08-19 IE IE2002/82A patent/IE55377B1/en unknown
- 1982-08-19 NZ NZ201643A patent/NZ201643A/xx unknown
- 1982-08-19 IL IL66580A patent/IL66580A/xx unknown
- 1982-08-20 JP JP57143479A patent/JPS5839668A/ja active Granted
-
1983
- 1983-12-22 US US06/564,399 patent/US4515944A/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8110 | Request for examination paragraph 44 | ||
8139 | Disposal/non-payment of the annual fee |