DE3046979A1 - Verfahren und vorrichtung fuer massentransferoperationen auf immunoassay- und anderen anwendungsgebieten - Google Patents

Verfahren und vorrichtung fuer massentransferoperationen auf immunoassay- und anderen anwendungsgebieten

Info

Publication number
DE3046979A1
DE3046979A1 DE19803046979 DE3046979A DE3046979A1 DE 3046979 A1 DE3046979 A1 DE 3046979A1 DE 19803046979 DE19803046979 DE 19803046979 DE 3046979 A DE3046979 A DE 3046979A DE 3046979 A1 DE3046979 A1 DE 3046979A1
Authority
DE
Germany
Prior art keywords
separator
mixer
mixing container
immunoassay
mixing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19803046979
Other languages
German (de)
English (en)
Other versions
DE3046979C2 (enExample
Inventor
Michael Prof. Cais
Moshe Haifa Shimoni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technion Research and Development Foundation Ltd
Original Assignee
Technion Research and Development Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion Research and Development Foundation Ltd filed Critical Technion Research and Development Foundation Ltd
Publication of DE3046979A1 publication Critical patent/DE3046979A1/de
Application granted granted Critical
Publication of DE3046979C2 publication Critical patent/DE3046979C2/de
Granted legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/0015—Feeding of the particles in the reactor; Evacuation of the particles out of the reactor
    • B01J8/003—Feeding of the particles in the reactor; Evacuation of the particles out of the reactor in a downward flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/18—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles
    • B01J8/24—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles according to "fluidised-bed" technique
    • B01J8/34—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles according to "fluidised-bed" technique with stationary packing material in the fluidised bed, e.g. bricks, wire rings, baffles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/801—Electron dense compounds, e.g. ferritin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/804—Radioisotope, e.g. radioimmunoassay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/816—Alkaloids, amphetamines, and barbiturates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Combustion & Propulsion (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
DE19803046979 1979-12-12 1980-12-12 Verfahren und vorrichtung fuer massentransferoperationen auf immunoassay- und anderen anwendungsgebieten Granted DE3046979A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL58943A IL58943A (en) 1979-12-12 1979-12-12 Method and device for mass transfer operations in immunoassays and other applications

Publications (2)

Publication Number Publication Date
DE3046979A1 true DE3046979A1 (de) 1981-10-01
DE3046979C2 DE3046979C2 (enExample) 1989-05-18

Family

ID=11051493

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19803046979 Granted DE3046979A1 (de) 1979-12-12 1980-12-12 Verfahren und vorrichtung fuer massentransferoperationen auf immunoassay- und anderen anwendungsgebieten

Country Status (12)

Country Link
US (1) US4454231A (enExample)
JP (1) JPS56161801A (enExample)
BE (1) BE886517A (enExample)
CA (1) CA1158839A (enExample)
DE (1) DE3046979A1 (enExample)
FR (1) FR2471204A1 (enExample)
GB (1) GB2064357B (enExample)
IL (1) IL58943A (enExample)
IT (1) IT1141126B (enExample)
NL (1) NL189801C (enExample)
SE (1) SE448403B (enExample)
ZA (1) ZA807508B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL56839A0 (en) * 1979-03-11 1979-05-31 Technion Res & Dev Foundation Improvement in specific binding assay technique
IL60645A (en) * 1980-07-21 1984-02-29 Cais Michael Method and device for mass transfer and separation through selective barriers
IL63363A (en) * 1981-07-20 1986-08-31 Cais Michael Non-centrifugation method for immunoassay of materials
US4775635A (en) * 1985-04-12 1988-10-04 E. I. Du Pont De Nemours And Company Rapid assay processor
DE3682502D1 (de) * 1985-08-21 1991-12-19 Biotope Inc Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests.
US5073341A (en) * 1985-08-21 1991-12-17 Biotope, Inc. Devices for conducting specific binding assays
US4800020A (en) * 1987-05-21 1989-01-24 Xydex Corporation Piston filtering device
JP2854058B2 (ja) * 1987-12-01 1999-02-03 ベーリンガー マンヘイム コーポレイション アッセイを実施するための方法及び装置
US4891134A (en) * 1988-01-25 1990-01-02 Abbott Laboratories Sample filtration device
US4990253A (en) * 1988-01-25 1991-02-05 Abbott Laboratories Fluid sample filtration device
US5114858A (en) * 1990-06-26 1992-05-19 E. I. Du Pont De Nemours And Company Cellular component extraction process in a disposable filtration vessel
CA2933491A1 (en) * 2013-12-16 2015-06-25 Dow Global Technologies Llc Method for analysis of trace levels of chemical additives in oil recovery production fluids
CN108654138B (zh) * 2017-04-01 2023-06-16 四川大学 一种离心力微流体萃取装置及其萃取方法
US11590463B2 (en) 2017-06-28 2023-02-28 University Of Tasmania Liquid-liquid mixing device suitable for sample preparation by liquid-liquid extraction
JP7276203B2 (ja) 2020-03-06 2023-05-18 横河電機株式会社 情報処理装置、情報処理方法、及びプログラム
JP7276204B2 (ja) 2020-03-06 2023-05-18 横河電機株式会社 情報処理装置、情報処理方法、及びプログラム

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3355098A (en) * 1964-07-06 1967-11-28 Bioconsultants Inc Serum separation apparatus and method
US3661265A (en) * 1970-07-27 1972-05-09 Contemporary Research And Dev Serum separator type container
DE2415618A1 (de) * 1974-03-30 1975-10-09 Sarstedt Kunststoff Filtervorrichtung zum trennen von blutfraktionen

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2524362A (en) * 1947-07-19 1950-10-03 Arthur E Smith Disposable ampoule syringe
US3068855A (en) * 1957-04-29 1962-12-18 Jr Norman B Furlong Disposable blood-gas analyzer
US3449081A (en) * 1965-03-29 1969-06-10 Electronic Instr Co Test kit
DE6901705U (de) * 1969-01-17 1969-06-04 Pfeiffer Vakuumtechnik Vorrichtung zum aufbereiten, z.b. mischen und/oder homogenisieren von stoffen
US3586064A (en) * 1969-09-03 1971-06-22 Metropolitan Pathology Lab Inc Blood serum collection tube and method of collection
DE2346313A1 (de) * 1973-09-14 1975-03-27 Kettenbach Fab Chem A Verfahren und vorrichtung zum zwangslaeufig definierten messen und schnellen luftfreien mischen mehrerer komponenten, insbesondere elastomerer abdruckmassen
FR2274918A1 (fr) * 1974-03-30 1976-01-09 Sarstedt Kunststoff Dispositif de filtrage pour la separation de fractions de sang
DE2422260B2 (de) * 1974-05-08 1979-04-12 Compur-Electronic Gmbh, 8000 Muenchen Einrichtung zur Herstellung einer optisch zu untersuchenden Meßflüssigkeit
US4022576A (en) * 1975-06-09 1977-05-10 I. C. L. Scientific Method and apparatus for preparation of liquids containing suspended material for examination
FR2343496A1 (fr) * 1976-03-12 1977-10-07 Commissariat Energie Atomique Dispositif automatique d'extraction liquide-liquide.
US4087248A (en) * 1976-07-26 1978-05-02 Miles Laughton E Multiple assay machine and method
US4071319A (en) * 1976-11-26 1978-01-31 Becton, Dickinson And Company Contaminant detector
US4197287A (en) * 1977-06-10 1980-04-08 Ventrex Laboratories Inc. Method and apparatus for performing in nitro clinical diagnostic tests using a solid phase assay system having special utility for use with automatic pipetting equipment
US4254082A (en) * 1978-06-12 1981-03-03 Miles Laboratories, Inc. Specific binding-adsorbent assay test means

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3355098A (en) * 1964-07-06 1967-11-28 Bioconsultants Inc Serum separation apparatus and method
US3661265A (en) * 1970-07-27 1972-05-09 Contemporary Research And Dev Serum separator type container
DE2415618A1 (de) * 1974-03-30 1975-10-09 Sarstedt Kunststoff Filtervorrichtung zum trennen von blutfraktionen

Also Published As

Publication number Publication date
SE8008664L (sv) 1981-06-13
JPS6228681B2 (enExample) 1987-06-22
FR2471204B1 (enExample) 1984-07-13
SE448403B (sv) 1987-02-16
GB2064357A (en) 1981-06-17
IL58943A (en) 1983-05-15
NL8006730A (nl) 1981-07-16
BE886517A (fr) 1981-04-01
US4454231A (en) 1984-06-12
NL189801B (nl) 1993-03-01
GB2064357B (en) 1984-08-08
ZA807508B (en) 1982-01-27
JPS56161801A (en) 1981-12-12
IL58943A0 (en) 1980-03-31
FR2471204A1 (fr) 1981-06-19
IT1141126B (it) 1986-10-01
DE3046979C2 (enExample) 1989-05-18
CA1158839A (en) 1983-12-20
NL189801C (nl) 1993-08-02
IT8026541A0 (it) 1980-12-10

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee