DE3682502D1 - Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests. - Google Patents
Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests.Info
- Publication number
- DE3682502D1 DE3682502D1 DE8686905538T DE3682502T DE3682502D1 DE 3682502 D1 DE3682502 D1 DE 3682502D1 DE 8686905538 T DE8686905538 T DE 8686905538T DE 3682502 T DE3682502 T DE 3682502T DE 3682502 D1 DE3682502 D1 DE 3682502D1
- Authority
- DE
- Germany
- Prior art keywords
- devices
- specific binding
- separating
- mixing
- label
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/806—Electrical property or magnetic property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Sampling And Sample Adjustment (AREA)
- Accessories For Mixers (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76810885A | 1985-08-21 | 1985-08-21 | |
PCT/US1986/001720 WO1987001206A1 (en) | 1985-08-21 | 1986-08-21 | Methods and devices for separating, mixing, and detecting components in specific binding assays |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3682502D1 true DE3682502D1 (de) | 1991-12-19 |
Family
ID=25081541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686905538T Expired - Fee Related DE3682502D1 (de) | 1985-08-21 | 1986-08-21 | Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4868130A (de) |
EP (1) | EP0233939B1 (de) |
JP (1) | JP2591738B2 (de) |
KR (1) | KR880700269A (de) |
AT (1) | ATE69507T1 (de) |
CA (1) | CA1292092C (de) |
DE (1) | DE3682502D1 (de) |
WO (1) | WO1987001206A1 (de) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5073341A (en) * | 1985-08-21 | 1991-12-17 | Biotope, Inc. | Devices for conducting specific binding assays |
US5470711A (en) * | 1986-03-26 | 1995-11-28 | Synbiotics Corporation | Saliva enhancement reagent for feline leukemia virus elisa |
SE8703733L (sv) * | 1987-09-28 | 1989-03-29 | Ragnar Soedergaard | Analysmetod foer bestaemning av procent fri substans i biologiska vaetskor genom jaemviktsfoerdelning i olja/vatten system |
WO1989005456A1 (en) * | 1987-12-01 | 1989-06-15 | Biotope, Inc. | Methods and devices for conducting assays |
US5145784A (en) * | 1988-05-04 | 1992-09-08 | Cambridge Biotech Corporation | Double capture assay method employing a capillary flow device |
US5484735A (en) * | 1989-08-23 | 1996-01-16 | Northwestern University | Immunoassay of glycosylated proteins employing antibody directed to reductively glycosylated N-terminal amino acids |
GB2239197B (en) * | 1989-12-22 | 1993-10-06 | Syntex Inc | Method for separating components in a mixture |
US5279936A (en) * | 1989-12-22 | 1994-01-18 | Syntex (U.S.A.) Inc. | Method of separation employing magnetic particles and second medium |
US5223393A (en) * | 1990-06-12 | 1993-06-29 | Microgenics Corporation | Detection of analytes having binding sites for at least two binding moieties |
US6703236B2 (en) * | 1990-11-29 | 2004-03-09 | Applera Corporation | Thermal cycler for automatic performance of the polymerase chain reaction with close temperature control |
KR100236506B1 (ko) * | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
US5506114A (en) * | 1992-02-07 | 1996-04-09 | Osborn Laboratories | Methods and kits for detecting the presence or concentration of biological analytes |
US5629168A (en) * | 1992-02-10 | 1997-05-13 | British Technology Group Limited | Chemiluminescent enhancers |
GB2312746B (en) * | 1996-04-24 | 2000-07-19 | Molecular Light Technology Lim | Detection of an analyte in a Water Immiscible Solvent |
US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
US6143496A (en) * | 1997-04-17 | 2000-11-07 | Cytonix Corporation | Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly |
US6752965B2 (en) * | 1998-03-06 | 2004-06-22 | Abner Levy | Self resealing elastomeric closure |
US6030582A (en) * | 1998-03-06 | 2000-02-29 | Levy; Abner | Self-resealing, puncturable container cap |
EP2045334A1 (de) | 1998-06-24 | 2009-04-08 | Illumina, Inc. | Dekodierung von Arraysensoren mit Mikrosphären |
CA2283597C (en) | 1998-10-02 | 2008-02-05 | Ortho-Clinical Diagnostics, Inc. | Reduced cortisol conjugates |
ATE427159T1 (de) † | 1999-05-14 | 2009-04-15 | Gen Probe Inc | Fluid-transfer-gerat zur verwendung mit durchdringbarer kappe |
US6623982B1 (en) * | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
US7759067B2 (en) * | 2001-03-19 | 2010-07-20 | Gyros Patent Ab | Method for determining the amount of an analyte with a disc-shaped microfluidic device |
CA2513985C (en) | 2003-01-21 | 2012-05-29 | Illumina Inc. | Chemical reaction monitor |
US20050181513A1 (en) * | 2004-02-18 | 2005-08-18 | Viorica Lopez-Avila | Methods and compositions for assessing a sample by MAILDI mass spectrometry |
US7776531B1 (en) | 2004-03-25 | 2010-08-17 | Illumina, Inc. | Compositions and methods for stabilizing surface bound probes |
EP3167961A1 (de) | 2004-04-08 | 2017-05-17 | Biomatrica, Inc. | Integration von probenlagerung und probenverwaltung für biowissenschaften |
US9488665B2 (en) * | 2005-09-13 | 2016-11-08 | Chrome Red Technologies, Llc | Magnetic particle tagged reagents and techniques |
US20070113908A1 (en) * | 2005-11-18 | 2007-05-24 | The Ohio State University And Bioloc, Inc. | Valve for microfluidic chips |
US9274082B2 (en) * | 2007-08-27 | 2016-03-01 | Technion Research & Development Foundation Limited | pH gradients controlled by electrolysis, and their use in isoelectric focusing |
MX2011004169A (es) * | 2008-10-31 | 2011-09-27 | Bio Merieux Inc | Metodos para la separacion y caracterizacion de microorganismos utilizando agentes identificadores. |
BRPI1015218B1 (pt) * | 2009-05-07 | 2019-10-08 | Biomerieux Inc. | Métodos para determinar a resistência antimicrobiana |
CN103154735B (zh) * | 2009-05-11 | 2018-10-02 | 连接Dx股份有限公司 | 用于检测分析物的方法和组合物 |
CA2770518A1 (en) | 2009-08-18 | 2011-02-24 | Technion Research & Development Foundation Ltd. | Methods and devices of separating molecular analytes |
CN102483390B (zh) | 2009-08-18 | 2014-11-19 | 工业研究与发展基金会有限公司 | 质子浓度形貌、用于产生其的方法和装置 |
KR20120107497A (ko) | 2009-12-17 | 2012-10-02 | 아박시스, 인크. | 샘플 내 분석물을 검출하기 위한 신규 분석 및 그것과 관련된 키트 및 조성물 |
WO2012018639A2 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
EP2598660B1 (de) | 2010-07-26 | 2017-03-15 | Biomatrica, INC. | Zusammensetzungen zur stabilisierung von dna, rna und proteinen in blut- und anderen biologischen proben während des transports und der lagerung bei umgebungstemperaturen |
US20130071946A1 (en) | 2011-09-21 | 2013-03-21 | Roche Molecular Systems, Inc. | Suspension Container For Binding Particles For The Isolation Of Biological Material |
EP2773221B1 (de) | 2011-11-04 | 2019-01-09 | Bio-Rad Laboratories, Inc. | Gleichzeitige reinigung von zellkomponenten |
US9766207B2 (en) | 2011-11-04 | 2017-09-19 | Bio-Rad Laboratories, Inc. | Affinity methods and compositions employing electronic control of pH |
US20130164860A1 (en) * | 2011-11-04 | 2013-06-27 | Technion Research & Development Foundation Ltd. | Affinity methods and compositions employing electronic control of ph |
US9658195B2 (en) | 2012-02-15 | 2017-05-23 | Bio-Rad Laboratories, Inc. | Electronic control of pH and ionic strength |
US9321012B2 (en) | 2012-04-04 | 2016-04-26 | Bio-Rad Laboratories, Inc. | Electronic protein fractionation |
US20130280146A1 (en) * | 2012-04-18 | 2013-10-24 | Rarecyte, Inc. | Systems and methods for separation and analysis of target analytes |
EP3249054A1 (de) | 2012-12-20 | 2017-11-29 | Biomatrica, INC. | Formulierungen und verfahren zur stabilisierung von pcr-reagenzien |
US10364453B1 (en) * | 2013-02-04 | 2019-07-30 | The United States Of America, As Represented By The Secretary Of The Navy | Detecting of bacteria using fluorescently-labeled phage immobilized on an optically transparent surface |
EP3828284A1 (de) | 2013-03-15 | 2021-06-02 | Abbott Molecular Inc. | Einstufiges verfahren zur aufreinigung von nukleinsäuren |
EP3154338B1 (de) | 2014-06-10 | 2020-01-29 | Biomatrica, INC. | Stabilisierung von thrombozyten bei umgebungstemperatur |
WO2017100212A1 (en) | 2015-12-08 | 2017-06-15 | Biomatrica, Inc. | Reduction of erythrocyte sedimentation rate |
US11382185B2 (en) * | 2016-01-08 | 2022-07-05 | Siemens Healthcare Diagnostics Inc. | Heating element for sensor array |
IT201600079328A1 (it) * | 2016-07-28 | 2018-01-28 | Altergon Sa | Metodo migliorato per la decontaminazione di materiale biologico mediante partizione e inattivazione |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1411382A (en) * | 1971-12-16 | 1975-10-22 | Radiochemical Centre Ltd | Methods of analysis |
US3852194A (en) * | 1972-12-11 | 1974-12-03 | Corning Glass Works | Apparatus and method for fluid collection and partitioning |
GB1566098A (en) * | 1975-11-14 | 1980-04-30 | Nat Res Dev | Separation of solid and liquid components of mixtures |
GB1533272A (en) * | 1976-02-13 | 1978-11-22 | Radiochemical Centre Ltd | Centrifuge tube |
IL56839A0 (en) * | 1979-03-11 | 1979-05-31 | Technion Res & Dev Foundation | Improvement in specific binding assay technique |
IL58943A (en) * | 1979-12-12 | 1983-05-15 | Cais Michael | Method and device for mass transfer operations in immunoassays and other applications |
JPS58205854A (ja) * | 1982-05-25 | 1983-11-30 | Mihama Hisaharu | 潜血反応検査用の固定化抗体 |
DE3222962A1 (de) * | 1982-06-19 | 1983-12-22 | Bayer Ag, 5090 Leverkusen | Siliconpasten fuer die trennung von blutproben |
AU1912783A (en) * | 1982-09-15 | 1984-03-22 | Ortho Diagnostic Systems Inc. | Carousel microparticle separating, washing + reading device |
FI844027A (fi) * | 1984-10-12 | 1986-04-13 | Labsystems Oy | Immunologiskt bestaemningsfoerfarande. |
-
1986
- 1986-08-21 DE DE8686905538T patent/DE3682502D1/de not_active Expired - Fee Related
- 1986-08-21 CA CA000516560A patent/CA1292092C/en not_active Expired - Fee Related
- 1986-08-21 AT AT86905538T patent/ATE69507T1/de not_active IP Right Cessation
- 1986-08-21 JP JP61504751A patent/JP2591738B2/ja not_active Expired - Fee Related
- 1986-08-21 WO PCT/US1986/001720 patent/WO1987001206A1/en active IP Right Grant
- 1986-08-21 EP EP86905538A patent/EP0233939B1/de not_active Expired - Lifetime
-
1987
- 1987-02-20 US US07/017,318 patent/US4868130A/en not_active Expired - Lifetime
- 1987-04-21 KR KR870700345A patent/KR880700269A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR880700269A (ko) | 1988-02-22 |
EP0233939B1 (de) | 1991-11-13 |
EP0233939A1 (de) | 1987-09-02 |
ATE69507T1 (de) | 1991-11-15 |
JP2591738B2 (ja) | 1997-03-19 |
US4868130A (en) | 1989-09-19 |
WO1987001206A1 (en) | 1987-02-26 |
JPS63501172A (ja) | 1988-04-28 |
CA1292092C (en) | 1991-11-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |