ES2068844T3 - Dispositivo analitico en fase solida y metodo para su utilizacion. - Google Patents
Dispositivo analitico en fase solida y metodo para su utilizacion.Info
- Publication number
- ES2068844T3 ES2068844T3 ES89105114T ES89105114T ES2068844T3 ES 2068844 T3 ES2068844 T3 ES 2068844T3 ES 89105114 T ES89105114 T ES 89105114T ES 89105114 T ES89105114 T ES 89105114T ES 2068844 T3 ES2068844 T3 ES 2068844T3
- Authority
- ES
- Spain
- Prior art keywords
- analyte
- assay
- solid phase
- analytical device
- phase analytical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/521—Single-layer analytical elements
- G01N33/523—Single-layer analytical elements the element being adapted for a specific analyte
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/528—Atypical element structures, e.g. gloves, rods, tampons, toilet paper
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5761—Hepatitis B
- G01N33/5764—Hepatitis B surface antigen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Reproductive Health (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Un dispositivo de prueba para utilizar en un ensayo de fijación para determinar la presencia o cantidad de un analito en una muestra líquida con la adición de la muestra, reactivos adecuados y marca a un emplazamiento de reacción, en donde dicho emplazamiento de reacción tiene una primera área de control (30), una segunda área de control (32) que incluye medios para representar una respuesta detectable indicativa de un resultado de ensayo válido, y un área de fijación de analito (34) incluyendo medios para representar un resultado detectable indicativo de la presencia o cantidad del analito en la muestra fluida; caracterizado en que dicho dispositivo es una tira cromatográfica porosa (11) que tiene un emplazamiento de contacto a diferencia de dicho emplazamiento de reacción para poner en contacto una muestra fluida y medios (12) para transportar la muestra fluida por capilaridad o mecha al emplazamiento de reacción, tal que dicha muestra fluida uye a través de dicho emplazamiento de reacción de extremo a extremo; y en el que el símbolo detectable producido por la segunda área de control (32) interactúa con el símbolo producido por el área de fijación de analito (34) en la presencia de analito para formar un símbolo interactivo representativo de un resultado positivo, mientras que el símbolo producido por la segunda área de control (32) tomado sólo es representativo de un resultado negativo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/173,979 US4916056A (en) | 1986-02-18 | 1988-03-28 | Solid-phase analytical device and method for using same |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2068844T3 true ES2068844T3 (es) | 1995-05-01 |
Family
ID=22634314
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89105114T Expired - Lifetime ES2068844T3 (es) | 1988-03-28 | 1989-03-22 | Dispositivo analitico en fase solida y metodo para su utilizacion. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4916056A (es) |
EP (1) | EP0335244B1 (es) |
JP (1) | JP2818191B2 (es) |
KR (1) | KR920009420B1 (es) |
AT (1) | ATE116443T1 (es) |
AU (1) | AU618586B2 (es) |
CA (1) | CA1332807C (es) |
DE (1) | DE68920176T2 (es) |
ES (1) | ES2068844T3 (es) |
Families Citing this family (152)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5622871A (en) | 1987-04-27 | 1997-04-22 | Unilever Patent Holdings B.V. | Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents |
US6060237A (en) | 1985-02-26 | 2000-05-09 | Biostar, Inc. | Devices and methods for optical detection of nucleic acid hybridization |
TW203120B (es) * | 1985-10-04 | 1993-04-01 | Abbott Lab | |
US5160701A (en) * | 1986-02-18 | 1992-11-03 | Abbott Laboratories | Solid-phase analytical device and method for using same |
US5250412A (en) * | 1987-03-23 | 1993-10-05 | Diamedix Corporation | Swab device and method for collecting and analyzing a sample |
EP0291194B8 (en) | 1987-04-27 | 2003-10-22 | Inverness Medical Switzerland GmbH | Immunoassays and devices therefor |
US5120643A (en) * | 1987-07-13 | 1992-06-09 | Abbott Laboratories | Process for immunochromatography with colloidal particles |
US5073344A (en) * | 1987-07-17 | 1991-12-17 | Porex Technologies Corp. | Diagnostic system employing a unitary substrate to immobilize microspheres |
WO1989001626A1 (en) * | 1987-08-19 | 1989-02-23 | Flemming Gmbh | Process and device for detecting an antigen or antibody in a liquid test specimen |
DE3740471A1 (de) * | 1987-11-28 | 1989-06-08 | Boehringer Mannheim Gmbh | Testtraeger zur analyse einer probenfluessigkeit und verfahren zu seiner herstellung |
CA1339723C (en) * | 1988-01-19 | 1998-03-17 | Philip Mcmahon | Immunoassay with multiple test spots |
AU2684488A (en) * | 1988-06-27 | 1990-01-04 | Carter-Wallace, Inc. | Test device and method for colored particle immunoassay |
IT1227293B (it) * | 1988-10-06 | 1991-04-05 | Boehringer Biochemia Srl | Dispositivo e metodo per la diagnosi di gravidanza |
JPH02176466A (ja) * | 1988-12-27 | 1990-07-09 | Mochida Pharmaceut Co Ltd | 液性試料中の特定物質の測定方法および測定器具 |
CA2008304C (en) * | 1989-01-31 | 2001-03-27 | Craig S. Hill | Assay for bone alkaline phosphatase |
US6352862B1 (en) | 1989-02-17 | 2002-03-05 | Unilever Patent Holdings B.V. | Analytical test device for imuno assays and methods of using same |
GB2233090B (en) * | 1989-04-19 | 1992-03-25 | Pall Corp | Multilayered diagnostic device and method |
US5100620A (en) * | 1989-05-15 | 1992-03-31 | Miles, Inc. | Capillary tube/gap reagent format |
EP0401913B1 (en) * | 1989-06-05 | 1995-01-25 | Janssen Pharmaceutica N.V. | A solid phase assay for use with a physical developer |
US5185127A (en) * | 1989-09-21 | 1993-02-09 | Becton, Dickinson And Company | Test device including flow control means |
US5075078A (en) * | 1989-10-05 | 1991-12-24 | Abbott Laboratories | Self-performing immunochromatographic device |
GB2241329B (en) * | 1990-01-10 | 1994-02-09 | Princeton Biomeditech Corp | No wash immunoassay |
KR910014705A (ko) * | 1990-01-10 | 1991-08-31 | 원본미기재 | 세척이 필요없은 딥스틱(Dipstick) 형태의 이뮤노어세이(Immunoasssay)장치 |
KR910014706A (ko) * | 1990-01-10 | 1991-08-31 | 원본미기재 | 세척이 필요없는 개량된 이뮤노어세이(immunoassay)장치 |
CA2032114A1 (en) * | 1990-01-22 | 1991-07-23 | Brian A. Snyder | Antibody composition for actinobacillus actinomycetemcomitans and its use in diagnostics |
CA2032959A1 (en) * | 1990-01-22 | 1991-07-23 | Brian A. Snyder | Article, test kit and sandwich assay for the detection of bacteroides intermedius, bacteroides gingivalis or actinobacillus actinomycetemcomotams |
US5212061A (en) * | 1990-01-22 | 1993-05-18 | Eastman Kodak Company | Direct binding assay for the determination of a bacteroids organism |
CA2032112A1 (en) * | 1990-01-22 | 1991-07-23 | Brian Anthony Snyder | Screening assay for microorganisms associated with periodontal diseases, article and kit useful therein |
CA2028681A1 (en) * | 1990-01-22 | 1991-07-23 | Brian A. Snyder | Differentiation of microorganisms associated with periodontal diseases, article and kit useful therein |
US5104619A (en) * | 1990-01-24 | 1992-04-14 | Gds Technology, Inc. | Disposable diagnostic system |
AU637480B2 (en) * | 1990-03-12 | 1993-05-27 | Biosite Diagnostics Incorporated | Bioassay device with non-absorbent textured capillary surface |
DE4012216A1 (de) * | 1990-04-14 | 1991-10-17 | Boehringer Mannheim Gmbh | Testtraeger fuer die analyse von fluessigkeiten |
CA2035595A1 (en) * | 1990-04-12 | 1991-10-13 | Carol A. Miller | Immunoassay test device with thread control element |
US5132085A (en) * | 1991-02-28 | 1992-07-21 | Eastman Kodak Company | Test device with novel control symbolism |
US5266497A (en) * | 1990-08-31 | 1993-11-30 | Japan Synthetic Rubber Co., Ltd. | Immunochromatographic assay with improved colored latex |
US5200321A (en) * | 1990-09-07 | 1993-04-06 | The United States Of America As Represented By The Secretary Of The Navy | Microassay on a card |
US5726064A (en) * | 1990-11-22 | 1998-03-10 | Applied Research Systems Ars Holding Nv | Method of assay having calibration within the assay |
EP1231282A3 (en) * | 1990-12-06 | 2005-05-18 | Affymetrix, Inc. | Methods and compositions for identification of polymers |
US5294698A (en) * | 1990-12-06 | 1994-03-15 | Bomalaski John S | Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis |
GB9026538D0 (en) * | 1990-12-06 | 1991-01-23 | Knight Scient Ltd | Filtration arrangement |
US5389338A (en) * | 1991-01-06 | 1995-02-14 | Orgenics Ltd. | Apparatus for dry chemical analysis of fluids |
JP3108115B2 (ja) * | 1991-03-28 | 2000-11-13 | ロート製薬株式会社 | イムノクロマトグラフ法による物質検出法 |
US5256543A (en) * | 1991-05-10 | 1993-10-26 | Sangstat Medical Corporation | HLA typing |
US5877028A (en) | 1991-05-29 | 1999-03-02 | Smithkline Diagnostics, Inc. | Immunochromatographic assay device |
US5998220A (en) | 1991-05-29 | 1999-12-07 | Beckman Coulter, Inc. | Opposable-element assay devices, kits, and methods employing them |
US5468648A (en) * | 1991-05-29 | 1995-11-21 | Smithkline Diagnostics, Inc. | Interrupted-flow assay device |
US6168956B1 (en) | 1991-05-29 | 2001-01-02 | Beckman Coulter, Inc. | Multiple component chromatographic assay device |
US5607863A (en) * | 1991-05-29 | 1997-03-04 | Smithkline Diagnostics, Inc. | Barrier-controlled assay device |
US5869345A (en) * | 1991-05-29 | 1999-02-09 | Smithkline Diagnostics, Inc. | Opposable-element assay device employing conductive barrier |
US5686315A (en) * | 1991-06-14 | 1997-11-11 | Quidel Corporation | Assay device for one step detection of analyte |
WO1993018398A1 (en) * | 1992-03-10 | 1993-09-16 | Quidel Corporation | Red blood cell separation means for specific binding assays |
US5268146A (en) * | 1992-03-25 | 1993-12-07 | Litmus Concepts, Inc. | Fast response test panel |
US6156270A (en) | 1992-05-21 | 2000-12-05 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
US6905882B2 (en) | 1992-05-21 | 2005-06-14 | Biosite, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
US7524456B1 (en) | 1992-05-21 | 2009-04-28 | Biosite Incorporated | Diagnostic devices for the controlled movement of reagents without membranes |
US6767510B1 (en) * | 1992-05-21 | 2004-07-27 | Biosite, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
US5395754A (en) * | 1992-07-31 | 1995-03-07 | Hybritech Incorporated | Membrane-based immunoassay method |
EP0583980A1 (en) * | 1992-08-20 | 1994-02-23 | Eli Lilly And Company | Method for generating monoclonal antibodies from rabbits |
US5356782A (en) * | 1992-09-03 | 1994-10-18 | Boehringer Mannheim Corporation | Analytical test apparatus with on board negative and positive control |
US6093546A (en) * | 1992-09-03 | 2000-07-25 | Roche Diagnostics | Process for preparing test elements |
US5354692A (en) * | 1992-09-08 | 1994-10-11 | Pacific Biotech, Inc. | Analyte detection device including a hydrophobic barrier for improved fluid flow |
AU675251B2 (en) * | 1993-01-04 | 1997-01-30 | Becton Dickinson & Company | Flow-through hybridization assay for oligonucleotide sequences |
JP3299330B2 (ja) * | 1993-03-18 | 2002-07-08 | 持田製薬株式会社 | 簡易測定装置および方法 |
US5500375A (en) * | 1993-04-13 | 1996-03-19 | Serex, Inc. | Integrated packaging-holder device for immunochromatographic assays in flow-through or dipstick formats |
US6893816B1 (en) * | 1993-10-28 | 2005-05-17 | Houston Advanced Research Center | Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions |
US20010051350A1 (en) | 1995-05-02 | 2001-12-13 | Albert Nazareth | Diagnostic detection device and method |
IL113920A (en) * | 1995-05-30 | 1999-09-22 | Avraham Reinhartz | Apparatus and method for detection of analytes in a sample |
EP0882230A4 (en) * | 1995-11-17 | 2001-05-02 | Universal Healthwatch Inc | CHEMILUMINESCENCE ASSAY METHODS AND DEVICES FOR DETECTING TARGET ANALYTES |
US6750031B1 (en) | 1996-01-11 | 2004-06-15 | The United States Of America As Represented By The Secretary Of The Navy | Displacement assay on a porous membrane |
US5770086A (en) * | 1996-01-25 | 1998-06-23 | Eureka| Science Corp. | Methods and apparatus using hydrogels |
WO1997031268A1 (en) * | 1996-02-23 | 1997-08-28 | Universal Healthwatch, Inc. | Chromatographic strip having detection and control zones oriented parallel to the direction of flow |
US5660790A (en) * | 1996-08-13 | 1997-08-26 | Litmus Concepts, Inc. | PH and amine test elements |
US5879951A (en) | 1997-01-29 | 1999-03-09 | Smithkline Diagnostics, Inc. | Opposable-element assay device employing unidirectional flow |
US6057165A (en) * | 1997-02-07 | 2000-05-02 | Becton, Dickinson And Company | Quality control procedure for membrane flow-through diagnostic assay devices |
US6103536A (en) | 1997-05-02 | 2000-08-15 | Silver Lake Research Corporation | Internally referenced competitive assays |
US5939252A (en) | 1997-05-09 | 1999-08-17 | Lennon; Donald J. | Detachable-element assay device |
US6258548B1 (en) | 1997-06-05 | 2001-07-10 | A-Fem Medical Corporation | Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules |
DE19731465A1 (de) * | 1997-07-22 | 1999-01-28 | Boehringer Mannheim Gmbh | Verwendung von Kontrollflächen zur Detektion von Störproben in einem Nachweisverfahren |
SE9704935D0 (sv) | 1997-12-30 | 1997-12-30 | Pharmacia & Upjohn Diag Ab | Analysmetod med partiklar |
US6267722B1 (en) | 1998-02-03 | 2001-07-31 | Adeza Biomedical Corporation | Point of care diagnostic systems |
US6394952B1 (en) * | 1998-02-03 | 2002-05-28 | Adeza Biomedical Corporation | Point of care diagnostic systems |
USD432244S (en) * | 1998-04-20 | 2000-10-17 | Adeza Biomedical Corporation | Device for encasing an assay test strip |
USD434153S (en) * | 1998-04-20 | 2000-11-21 | Adeza Biomedical Corporation | Point of care analyte detector system |
US6355419B1 (en) | 1998-04-27 | 2002-03-12 | Hyseq, Inc. | Preparation of pools of nucleic acids based on representation in a sample |
US7640083B2 (en) * | 2002-11-22 | 2009-12-29 | Monroe David A | Record and playback system for aircraft |
US6372514B1 (en) | 1998-09-18 | 2002-04-16 | Syntron Bioresearch, Inc. | Even fluid front for liquid sample on test strip device |
US6140136A (en) * | 1998-09-18 | 2000-10-31 | Syntron Bioresearch, Inc. | Analytical test device and method of use |
US6490030B1 (en) | 1999-01-18 | 2002-12-03 | Verification Technologies, Inc. | Portable product authentication device |
US6261523B1 (en) | 1999-04-27 | 2001-07-17 | Agilent Technologies Inc. | Adjustable volume sealed chemical-solution-confinement vessel |
US6306665B1 (en) | 1999-10-13 | 2001-10-23 | A-Fem Medical Corporation | Covalent bonding of molecules to an activated solid phase material |
US6512580B1 (en) | 1999-10-27 | 2003-01-28 | Verification Technologies, Inc. | Method and apparatus for portable product authentication |
WO2001071341A1 (fr) * | 2000-03-24 | 2001-09-27 | Arkray, Inc. | Dispositif auxiliaire d'introduction d'echantillons |
US6653147B2 (en) * | 2000-03-31 | 2003-11-25 | Neogen Corporation | Apparatus and method for chemiluminescent assays |
US6699722B2 (en) | 2000-04-14 | 2004-03-02 | A-Fem Medical Corporation | Positive detection lateral-flow apparatus and method for small and large analytes |
US20030104492A1 (en) * | 2000-12-15 | 2003-06-05 | Albert Chu | Flow-through membrane assays for carbohydrates using labeled lectins |
US7531362B2 (en) | 2001-06-07 | 2009-05-12 | Medmira Inc. | Rapid diagnostic assay |
US6855561B2 (en) * | 2001-09-10 | 2005-02-15 | Quidel Corporation | Method for adding an apparent non-signal line to a lateral flow assay |
EP1430303A1 (en) * | 2001-09-17 | 2004-06-23 | F. Hoffmann-La Roche Ag | Embossed test strip system |
US7098041B2 (en) | 2001-12-11 | 2006-08-29 | Kimberly-Clark Worldwide, Inc. | Methods to view and analyze the results from diffraction-based diagnostics |
US7102752B2 (en) * | 2001-12-11 | 2006-09-05 | Kimberly-Clark Worldwide, Inc. | Systems to view and analyze the results from diffraction-based diagnostics |
EP1461615B1 (en) * | 2001-12-12 | 2007-03-28 | Proteome Systems Intellectual Property Pty Ltd. | Diagnostic testing process |
US20030119203A1 (en) * | 2001-12-24 | 2003-06-26 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay devices and methods for conducting assays |
US8367013B2 (en) * | 2001-12-24 | 2013-02-05 | Kimberly-Clark Worldwide, Inc. | Reading device, method, and system for conducting lateral flow assays |
US7432105B2 (en) * | 2002-08-27 | 2008-10-07 | Kimberly-Clark Worldwide, Inc. | Self-calibration system for a magnetic binding assay |
US7314763B2 (en) * | 2002-08-27 | 2008-01-01 | Kimberly-Clark Worldwide, Inc. | Fluidics-based assay devices |
US7285424B2 (en) | 2002-08-27 | 2007-10-23 | Kimberly-Clark Worldwide, Inc. | Membrane-based assay devices |
US20040106190A1 (en) * | 2002-12-03 | 2004-06-03 | Kimberly-Clark Worldwide, Inc. | Flow-through assay devices |
EP1567671A1 (en) * | 2002-12-04 | 2005-08-31 | PamGene B.V. | Method for probe hybridisation of immobilized genomic dna |
US20040121334A1 (en) * | 2002-12-19 | 2004-06-24 | Kimberly-Clark Worldwide, Inc. | Self-calibrated flow-through assay devices |
US7247500B2 (en) * | 2002-12-19 | 2007-07-24 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in membrane-based assay devices |
US7851209B2 (en) * | 2003-04-03 | 2010-12-14 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in assay devices |
US20040197819A1 (en) * | 2003-04-03 | 2004-10-07 | Kimberly-Clark Worldwide, Inc. | Assay devices that utilize hollow particles |
CA2538587A1 (en) * | 2003-09-19 | 2005-03-31 | Quidel Corporation | Iconic colorimetric test device with reduced susceptibility to false positive and false negative readings |
US7713748B2 (en) * | 2003-11-21 | 2010-05-11 | Kimberly-Clark Worldwide, Inc. | Method of reducing the sensitivity of assay devices |
US7943395B2 (en) * | 2003-11-21 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Extension of the dynamic detection range of assay devices |
US20050112703A1 (en) * | 2003-11-21 | 2005-05-26 | Kimberly-Clark Worldwide, Inc. | Membrane-based lateral flow assay devices that utilize phosphorescent detection |
US20050136550A1 (en) * | 2003-12-19 | 2005-06-23 | Kimberly-Clark Worldwide, Inc. | Flow control of electrochemical-based assay devices |
US7943089B2 (en) * | 2003-12-19 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Laminated assay devices |
JP4672263B2 (ja) * | 2004-01-27 | 2011-04-20 | デンカ生研株式会社 | 簡便な検出法、検出装置及び検出キットとその製法 |
US8465696B2 (en) * | 2004-02-03 | 2013-06-18 | Polymer Technology Systems, Inc. | Dry test strip with controlled flow and method of manufacturing same |
US7625721B2 (en) | 2004-02-03 | 2009-12-01 | Polymer Technology Systems, Inc. | Non-precipitating bodily fluid analysis system |
US20060062688A1 (en) * | 2004-02-03 | 2006-03-23 | Polymer Technology Systems, Inc. | Bodily fluid analysis system |
JP2007530946A (ja) * | 2004-03-23 | 2007-11-01 | クイデル コーポレイション | ハイブリッド相ラテラルフロー・アッセイ |
US8128871B2 (en) | 2005-04-22 | 2012-03-06 | Alverix, Inc. | Lateral flow assay systems and methods |
DE102004023402A1 (de) * | 2004-05-12 | 2005-12-08 | Roche Diagnostics Gmbh | Verfahren zur Erhöhung des dynamischen Messbereichs von auf spezifischen Bindereaktionen basierenden, insbesondere immunologischen Testelementen |
GB0412949D0 (en) * | 2004-06-10 | 2004-07-14 | Inverness Medical Switzerland | Improvements in or relating to lateral flow assay devices |
US7521226B2 (en) | 2004-06-30 | 2009-04-21 | Kimberly-Clark Worldwide, Inc. | One-step enzymatic and amine detection technique |
WO2006023679A1 (en) * | 2004-08-17 | 2006-03-02 | Polymer Technology Systems, Inc. | Apparatus and method for manufacturing bodily fluid test strip |
GB2420850A (en) | 2004-12-03 | 2006-06-07 | Orion Diagnostica Oy | Particle based binding assay |
US7704753B2 (en) * | 2005-03-03 | 2010-04-27 | Inverness Medical Switzerland Gmbh | Devices and methods for analyte assays with built-in result reporting using recognizable symbols |
US9891217B2 (en) | 2005-04-22 | 2018-02-13 | Alverix, Inc. | Assay test strips with multiple labels and reading same |
KR101255400B1 (ko) | 2005-05-23 | 2013-04-17 | 파디아 에이비 | 2 단계 횡 유동 검사 방법 및 장치 |
US7871568B2 (en) * | 2006-01-23 | 2011-01-18 | Quidel Corporation | Rapid test apparatus |
US7794656B2 (en) * | 2006-01-23 | 2010-09-14 | Quidel Corporation | Device for handling and analysis of a biological sample |
CN102680680B (zh) * | 2006-04-12 | 2015-03-18 | 艾博生物医药(杭州)有限公司 | 在控制区域上含有非蛋白捕获物质的检测装置 |
CN101021531B (zh) * | 2006-04-12 | 2012-11-28 | 艾博生物医药(杭州)有限公司 | 在控制区域上含有非蛋白捕获物质的检测装置 |
US20080057528A1 (en) * | 2006-08-30 | 2008-03-06 | Kimberly-Clark Worldwide, Inc. | Detection of hydrogen peroxide released by enzyme-catalyzed oxidation of an analyte |
US7569396B1 (en) | 2006-09-08 | 2009-08-04 | Purplecow Llc | Caffeine detection using internally referenced competitive assays |
US7749775B2 (en) * | 2006-10-03 | 2010-07-06 | Jonathan Scott Maher | Immunoassay test device and method of use |
US8012761B2 (en) * | 2006-12-14 | 2011-09-06 | Kimberly-Clark Worldwide, Inc. | Detection of formaldehyde in urine samples |
US7846383B2 (en) * | 2006-12-15 | 2010-12-07 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay device and absorbent article containing same |
US7919331B2 (en) * | 2006-12-21 | 2011-04-05 | Silver Lake Research Corporation | Chromatographic test strips for one or more analytes |
JP5066498B2 (ja) * | 2008-09-19 | 2012-11-07 | 富士フイルム株式会社 | アッセイ方法 |
DE102010032718A1 (de) * | 2010-07-23 | 2012-01-26 | Christoph Gienapp | Testgerät |
US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
US8828329B2 (en) | 2010-10-01 | 2014-09-09 | Church & Dwight, Co., Inc. | Electronic analyte assaying device |
CN103858009B (zh) | 2011-09-16 | 2016-05-18 | 克里多生物医药私人有限公司 | 分子诊断检测设备及使用方法 |
US9927443B2 (en) | 2015-04-10 | 2018-03-27 | Conquerab Inc. | Risk assessment for therapeutic drugs |
US20160313307A1 (en) * | 2015-04-23 | 2016-10-27 | Ted Titmus | Diagnostic test strip for oral samples and method of use therefore |
US9903866B2 (en) | 2016-04-05 | 2018-02-27 | Conquerab Inc. | Portable devices for detection of antibodies against therapeutic drugs |
MX2019001016A (es) * | 2016-07-25 | 2019-07-04 | Gentian As | Dispositivo de ensayo y metodo para la evaluacion de celulas sanguineas. |
CN112005116A (zh) * | 2018-02-02 | 2020-11-27 | 日本化学药品株式会社 | 生化反应用基体以及分析装置 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3260413A (en) * | 1964-08-31 | 1966-07-12 | Scientific Industries | Automatic chemical analyzer |
US3992096A (en) * | 1975-08-04 | 1976-11-16 | Minnesota Mining And Manufacturing Company | Detecting system |
US4059407A (en) * | 1976-04-14 | 1977-11-22 | Becton, Dickinson And Company | Disposable chemical indicators |
US4219335A (en) * | 1978-09-18 | 1980-08-26 | E. I. Du Pont De Nemours And Company | Immunochemical testing using tagged reagents |
US4540659A (en) * | 1981-04-17 | 1985-09-10 | Syva Company | Simultaneous calibration heterogeneous immunoassay |
US4533629A (en) * | 1981-04-17 | 1985-08-06 | Syva Company | Simultaneous calibration heterogeneous immunoassay |
US4340564A (en) * | 1980-07-21 | 1982-07-20 | Daryl Laboratories, Inc. | Immunoadsorptive surface coating for solid-phase immunosubstrate and solid-phase immunosubstrate |
DE3029579C2 (de) * | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut |
US4472353A (en) * | 1980-08-07 | 1984-09-18 | Gerald Moore | Gas detector badge |
US4366241A (en) * | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
US4558013A (en) * | 1983-04-08 | 1985-12-10 | Mast Immunosystems, Ltd. | Calibrated reaction measurement system |
US4496654A (en) * | 1983-04-08 | 1985-01-29 | Quidel | Detection of HCG with solid phase support having avidin coating |
US4541987A (en) * | 1983-09-29 | 1985-09-17 | Helena Laboratories Corporation | Test pad for detecting occult blood |
US4632901A (en) * | 1984-05-11 | 1986-12-30 | Hybritech Incorporated | Method and apparatus for immunoassays |
US4740468A (en) * | 1985-02-14 | 1988-04-26 | Syntex (U.S.A.) Inc. | Concentrating immunochemical test device and method |
US4649121A (en) * | 1985-02-26 | 1987-03-10 | Miles Laboratories, Inc. | Viability test device |
CA1272127A (en) * | 1985-04-04 | 1990-07-31 | Hybritech Incorporated | Solid phase system for use in ligand-receptor assays |
TW203120B (es) * | 1985-10-04 | 1993-04-01 | Abbott Lab | |
EP0264036B1 (en) * | 1986-10-16 | 1993-06-30 | Abbott Laboratories | Analytical device and method for detecting chlamydia trachomatis and neisseria gonorrhoeae |
DE3787078T2 (de) * | 1986-11-24 | 1993-12-09 | Abbott Lab | Proberichtwirkung für analytisches Festphasengerät. |
US4748042A (en) * | 1987-03-31 | 1988-05-31 | V-Tech, Inc. | Method and apparatus for imprinting membranes with patterns of antibody |
EP0299359A3 (en) * | 1987-07-16 | 1990-09-26 | Abbott Laboratories | Reagent delivery system for use in solid-phase analytical devices |
-
1988
- 1988-03-28 US US07/173,979 patent/US4916056A/en not_active Expired - Lifetime
-
1989
- 1989-03-21 AU AU31564/89A patent/AU618586B2/en not_active Ceased
- 1989-03-22 AT AT89105114T patent/ATE116443T1/de not_active IP Right Cessation
- 1989-03-22 DE DE68920176T patent/DE68920176T2/de not_active Expired - Lifetime
- 1989-03-22 EP EP89105114A patent/EP0335244B1/en not_active Expired - Lifetime
- 1989-03-22 ES ES89105114T patent/ES2068844T3/es not_active Expired - Lifetime
- 1989-03-23 CA CA000594550A patent/CA1332807C/en not_active Expired - Lifetime
- 1989-03-27 KR KR1019890003817A patent/KR920009420B1/ko not_active IP Right Cessation
- 1989-03-27 JP JP1076382A patent/JP2818191B2/ja not_active Expired - Fee Related
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ATE116443T1 (de) | 1995-01-15 |
DE68920176T2 (de) | 1995-05-11 |
KR890015016A (ko) | 1989-10-28 |
AU3156489A (en) | 1989-09-28 |
EP0335244A3 (en) | 1990-05-30 |
DE68920176D1 (de) | 1995-02-09 |
JPH01299464A (ja) | 1989-12-04 |
US4916056A (en) | 1990-04-10 |
CA1332807C (en) | 1994-11-01 |
KR920009420B1 (ko) | 1992-10-16 |
EP0335244A2 (en) | 1989-10-04 |
AU618586B2 (en) | 1992-01-02 |
JP2818191B2 (ja) | 1998-10-30 |
EP0335244B1 (en) | 1994-12-28 |
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