ATE91023T1 - Verfahren und vorrichtungen zur durchfuehrung von untersuchungen. - Google Patents

Verfahren und vorrichtungen zur durchfuehrung von untersuchungen.

Info

Publication number
ATE91023T1
ATE91023T1 AT89900551T AT89900551T ATE91023T1 AT E91023 T1 ATE91023 T1 AT E91023T1 AT 89900551 T AT89900551 T AT 89900551T AT 89900551 T AT89900551 T AT 89900551T AT E91023 T1 ATE91023 T1 AT E91023T1
Authority
AT
Austria
Prior art keywords
label
analyte
assay
assay mixture
methods
Prior art date
Application number
AT89900551T
Other languages
English (en)
Inventor
William R Hargreaves
Original Assignee
Biotope Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotope Inc filed Critical Biotope Inc
Application granted granted Critical
Publication of ATE91023T1 publication Critical patent/ATE91023T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G01N33/5304—Reaction vessels, e.g. agglutination plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/495—Transforming growth factor [TGF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/795—Porphyrin- or corrin-ring-containing peptides
    • G01N2333/805—Haemoglobins; Myoglobins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/969—Multiple layering of reactants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Mycology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT89900551T 1987-12-01 1988-11-30 Verfahren und vorrichtungen zur durchfuehrung von untersuchungen. ATE91023T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12794487A 1987-12-01 1987-12-01
EP89900551A EP0344276B1 (de) 1987-12-01 1988-11-30 Verfahren und vorrichtungen zur durchführung von untersuchungen
PCT/US1988/004273 WO1989005456A1 (en) 1987-12-01 1988-11-30 Methods and devices for conducting assays

Publications (1)

Publication Number Publication Date
ATE91023T1 true ATE91023T1 (de) 1993-07-15

Family

ID=22432784

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89900551T ATE91023T1 (de) 1987-12-01 1988-11-30 Verfahren und vorrichtungen zur durchfuehrung von untersuchungen.

Country Status (7)

Country Link
US (1) US6121055A (de)
EP (1) EP0344276B1 (de)
JP (1) JP2854058B2 (de)
AT (1) ATE91023T1 (de)
CA (1) CA1341076C (de)
DE (1) DE3882040T2 (de)
WO (1) WO1989005456A1 (de)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364591A (en) * 1992-06-01 1994-11-15 Eastman Kodak Company Device for moving a target-bearing solid through a liquid for detection while being contained
FR2697633B1 (fr) * 1992-10-21 1995-01-20 Pasteur Sanofi Diagnostics Procédé d'immunodiagnostic en matrice poreuse avec particules sensibilisées et dispositif pour sa mise en Óoeuvre.
US5342790A (en) * 1992-10-30 1994-08-30 Becton Dickinson And Company Apparatus for indirect fluorescent assay of blood samples
WO1994026414A1 (en) * 1993-05-17 1994-11-24 Syntex (U.S.A.) Inc. Reaction container for specific binding assays and method for its use
US5905028A (en) * 1994-05-17 1999-05-18 Gamma Biologicals, Inc. Method and apparatus useful for detecting bloodgroup antigens and antibodies
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
DE19903576C2 (de) * 1999-01-29 2001-02-22 Bodenseewerk Perkin Elmer Co Quantitative Bestimmung von Analyten in einem heterogenen System
US7361481B2 (en) * 1999-04-09 2008-04-22 Women's And Children's Hospital Diagnosis of lysosomal storage disorders using saposins and other markers
US6623982B1 (en) * 1999-07-12 2003-09-23 Immunivest Corporation Increased separation efficiency via controlled aggregation of magnetic nanoparticles
US6613285B1 (en) * 2000-09-25 2003-09-02 General Electric Company Reactor plate and method
ATE437216T1 (de) 2001-09-06 2009-08-15 Genomic Profiling Systems Inc Schnellnachweis replizierender zellen
AU2002361977A1 (en) * 2001-12-04 2003-06-17 Omx Gmbh Device and method for processing biological or chemical substances or substance mixtures thereof
US20030219469A1 (en) * 2002-02-11 2003-11-27 Kci Licensing, Inc. Environmental control device for tissue treatment
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
SE0203548D0 (sv) * 2002-12-02 2002-12-02 Biacore Ab Method of determining site-specificity and kit therefor
WO2006071770A2 (en) * 2004-12-23 2006-07-06 I-Stat Corporation Molecular diagnostics system and methods
US9057046B2 (en) 2005-09-26 2015-06-16 Rapid Micro Biosystems, Inc. Cassette containing growth medium
US7807354B2 (en) * 2005-12-28 2010-10-05 Agilent Technologies, Inc. Low volume hybridization
EP2004541A1 (de) * 2006-03-13 2008-12-24 Gyros Patent Ab Verbessertes lenken magnetischer teilchen
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
US8008034B2 (en) 2006-10-13 2011-08-30 Theranos, Inc. Reducing optical interference in a fluidic device
CN102027367B (zh) * 2008-02-29 2016-03-23 西北大学 促进生物反应的屏障
CN102224410B (zh) * 2008-09-24 2017-02-08 施特劳斯控股公司 用于测试分析物的成像分析仪
JP5283113B2 (ja) * 2008-10-03 2013-09-04 独立行政法人産業技術総合研究所 微量液滴の体積測定方法及び装置
US8652800B2 (en) * 2008-10-31 2014-02-18 Biomerieux, Inc. Method for separation, characterization and/or identification of microorganisms using spectroscopy
MX2011004169A (es) * 2008-10-31 2011-09-27 Bio Merieux Inc Metodos para la separacion y caracterizacion de microorganismos utilizando agentes identificadores.
CN102271814B (zh) * 2008-10-31 2015-07-08 生物梅里埃公司 用于微生物的分离、表征和/或鉴定的分离装置
US8647835B2 (en) * 2008-10-31 2014-02-11 BIO MéRIEUX, INC. Methods for separation, characterization and/or identification of microorganisms using spectroscopy
JP6182574B2 (ja) 2008-10-31 2017-08-16 ビオメリュー・インコーポレイテッド 分光法を使用した微生物の分離、キャラクタリゼーションおよび／または同定方法
EP2485844B1 (de) 2009-10-06 2020-07-22 Koninklijke Philips N.V. Magnetische probenreinigung
DE102010041621B4 (de) 2010-09-29 2016-11-03 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Verfahren zum Transport magnetischer Partikel
US9517472B2 (en) * 2010-12-21 2016-12-13 Shimadzu Corporation Device and method for processing target component in tube
US9442046B2 (en) 2011-06-19 2016-09-13 Abogen, Inc. Device for sample collection
JP5741872B2 (ja) * 2011-06-24 2015-07-01 株式会社島津製作所 容器に収容された物質の分割方法
WO2013070730A2 (en) 2011-11-07 2013-05-16 Rapid Micro Biosystems, Inc. Cassette for sterility testing
WO2013145901A1 (ja) * 2012-03-30 2013-10-03 株式会社島津製作所 分割可能な容器及び容器に収容された物質の分割方法
JP5954532B2 (ja) * 2012-04-05 2016-07-20 セイコーエプソン株式会社 核酸抽出用デバイス、核酸抽出用キット、核酸抽出用装置及び核酸抽出方法
JP6444859B2 (ja) 2012-04-16 2018-12-26 ラピッド マイクロ バイオシステムズ インコーポレイテッド 細胞培養デバイス
JP2013236559A (ja) * 2012-05-11 2013-11-28 Sharp Corp 反応検出方法
JP5483134B2 (ja) * 2012-10-09 2014-05-07 独立行政法人産業技術総合研究所 微量液滴の体積測定方法及び装置
JP6120518B2 (ja) * 2012-10-10 2017-04-26 公益財団法人かずさＤｎａ研究所 簡易測定器具
JP2014176306A (ja) * 2013-03-13 2014-09-25 Seiko Epson Corp 核酸増幅反応用カートリッジ
JP2014176304A (ja) * 2013-03-13 2014-09-25 Seiko Epson Corp 核酸増幅反応用カートリッジ
JP2014176305A (ja) * 2013-03-13 2014-09-25 Seiko Epson Corp 核酸増幅反応用カートリッジ
JP6431522B2 (ja) 2013-03-15 2018-11-28 アボツト・モレキユラー・インコーポレイテツド 核酸の精製のための１工程法
TWI499779B (zh) * 2013-07-04 2015-09-11 Ind Tech Res Inst 檢測晶片及其使用方法
CN103333680B (zh) * 2013-07-16 2015-05-27 北京化工大学 一种具有多色荧光特性的二苯基恶唑共晶材料及其制备方法
CN103808923A (zh) * 2013-11-25 2014-05-21 珠海迪尔生物工程有限公司 一种可移动式磁分离荧光免疫检测分析方法及装置
CN111514950A (zh) * 2013-12-20 2020-08-11 3M创新有限公司 使用分离液进行样品浓缩和检测的系统和方法
CN105828947B (zh) 2013-12-20 2017-09-29 3M创新有限公司 用于样品浓缩和检测的系统和方法
WO2016184924A1 (en) * 2015-05-19 2016-11-24 Bio-Rad Innovations Use of a low-density immiscible compound in a device for detecting an analyte in a sample
US10545139B2 (en) * 2015-06-16 2020-01-28 Curiox Biosystems Pte Ltd. Methods and devices for performing biological assays using magnetic components
US10850280B2 (en) * 2017-11-17 2020-12-01 Siemens Healthcare Diagnostics Inc. Method for internally coating a liquid test sample collection device with at least one anticoagulant compound, and devices and kits related thereto
US12031985B2 (en) 2018-04-19 2024-07-09 First Light Diagnostics, Inc. Detection of targets
JP7091891B2 (ja) * 2018-07-06 2022-06-28 株式会社島津製作所 磁性体粒子操作用容器
CA3115279A1 (en) 2018-10-04 2020-04-09 First Light Diagnostics, Inc. Analysis instrument
CA3120708A1 (en) 2018-11-20 2020-05-28 Spectrum Solutions, Llc Sample collection system including sealing cap and valve
CN109735437B (zh) * 2019-01-28 2022-04-19 长春长光辰英生物科学仪器有限公司 一种细胞弹射分选后用于细胞收集与处理的器皿及方法
US11701094B2 (en) 2019-06-20 2023-07-18 Spectrum Solutions L.L.C. Sample collection system including valve and plug assemblies
WO2021086313A1 (en) * 2019-10-29 2021-05-06 Hewlett-Packard Development Company, L.P. Concentrating biological components
US11162136B1 (en) 2020-04-15 2021-11-02 Enumerix, Inc. Systems and methods for generation of emulsions with suitable clarity with applications of use
US20230295549A1 (en) * 2020-08-20 2023-09-21 Danmarks Tekniske Universitet Methods, assembly and system for high-throughput, parallel monitoring of reaction systems
US12540948B2 (en) 2021-03-05 2026-02-03 Countable Labs, Inc. Systems and methods for generating droplets and performing digital analyses
WO2022187684A1 (en) 2021-03-05 2022-09-09 Enumerix, Inc. Systems and methods for generating droplets and performing digital analyses
JP2024519214A (ja) * 2021-05-06 2024-05-09 アボツト・モレキユラー・インコーポレイテツド 簡易試料抽出用組成物及び方法
WO2022256612A1 (en) 2021-06-04 2022-12-08 Enumerix, Inc. Compositions, methods, and systems for single cell barcoding and sequencing
US12252745B2 (en) 2021-09-02 2025-03-18 Enumerix, Inc. Detection and digital quantitation of multiple targets
EP4453246A4 (de) 2021-12-20 2025-12-24 Countable Labs Inc Nachweis und digitale quantifizierung mehrerer ziele
CN117205772A (zh) * 2023-08-03 2023-12-12 中国辐射防护研究院 一种可携式放射性甲基碘示踪气体发生装置

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1411382A (en) * 1971-12-16 1975-10-22 Radiochemical Centre Ltd Methods of analysis
US3865548A (en) * 1972-06-13 1975-02-11 Einstein Coll Med Analytical apparatus and process
US3852194A (en) * 1972-12-11 1974-12-03 Corning Glass Works Apparatus and method for fluid collection and partitioning
GB1566098A (en) * 1975-11-14 1980-04-30 Nat Res Dev Separation of solid and liquid components of mixtures
GB1533272A (en) * 1976-02-13 1978-11-22 Radiochemical Centre Ltd Centrifuge tube
US4038150A (en) * 1976-03-24 1977-07-26 J. K. And Susie L. Wadley Research Institute And Blood Bank Sample mixing and centrifugation apparatus
FI56750C (fi) * 1978-02-27 1980-03-10 Reijo Vihko Rekationskaerl foer engaongsbruk vid immunologiskt bestaemning
JPS5510590A (en) * 1978-05-04 1980-01-25 Wellcome Found Enzyme immunity quantity analysis
US4212948A (en) * 1978-10-18 1980-07-15 J. K. And Susie L. Wadley Research Institute And Blood Bank Apparatus for detecting microbial pathogens employing a cushioning agent
IL56839A0 (en) * 1979-03-11 1979-05-31 Technion Res & Dev Foundation Improvement in specific binding assay technique
IL58943A (en) * 1979-12-12 1983-05-15 Cais Michael Method and device for mass transfer operations in immunoassays and other applications
US4295974A (en) * 1980-05-05 1981-10-20 Sherwood Medical Industries Inc. Blood sample collection and phase separation device
CA1178257A (en) * 1980-05-08 1984-11-20 Toshiji Ichikawa Apparatus for separating blood
US4752562A (en) * 1981-01-23 1988-06-21 Baxter Travenol Laboratories, Inc. Detection of serum antibody and surface antigen by radial partition immunoassay
DE3222962C2 (de) * 1982-06-19 1987-02-19 Bayer Ag, 5090 Leverkusen Siliconpasten für die Trennung von Blutproben
FI844027A7 (fi) * 1984-10-12 1986-04-13 Labsystems Oy Immunologiskt bestaemningsfoerfarande.
DE3682502D1 (de) * 1985-08-21 1991-12-19 Biotope Inc Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests.
SE448323B (sv) * 1985-08-27 1987-02-09 Ersson Nils Olof Forfarande och anordnig att separera serum eller plasma fran blod
FI853523A0 (fi) * 1985-09-13 1985-09-13 Labsystems Oy Foerfarande foer utfoering av immunobestaemningar med hjaelp av enzymstaempel.
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
WO1987007403A1 (fr) * 1986-05-21 1987-12-03 Kabushiki Kaisha Komatsu Seisakusho Appareil de guidage pour des corps en mouvement sans equipage
DE3843610A1 (de) * 1988-01-13 1989-07-27 Stephan Dr Diekmann Trenn- oder reaktionssaeuleneinheit
US5108933A (en) * 1988-09-16 1992-04-28 Immunicon Corporation Manipulation of colloids for facilitating magnetic separations

Also Published As

Publication number Publication date
JP2854058B2 (ja) 1999-02-03
EP0344276A1 (de) 1989-12-06
CA1341076C (en) 2000-08-08
EP0344276B1 (de) 1993-06-23
JPH02502405A (ja) 1990-08-02
US6121055A (en) 2000-09-19
DE3882040D1 (de) 1993-07-29
WO1989005456A1 (en) 1989-06-15
DE3882040T2 (de) 1993-09-30

Similar Documents

Publication Publication Date Title
DE3882040D1 (de) Verfahren und vorrichtungen zur durchfuehrung von untersuchungen.
DE3682502D1 (de) Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests.
DE3851967D1 (de) Verfahren zur Bestimmung von Antikörpern.
ZA863086B (en) Multizone analytical element having detectable signal concentration zone
ES443619A1 (es) Aparato de ensayo para analizar una pluralidad de muestras liquidas.
KR890012165A (ko) 이온-포획 분석방법 및 장치
DE69416828D1 (de) Vorrichtung zur chromatographischen bestimmung, die einander entgegenstellbare teile enthalten
ATE80735T1 (de) Kolorimetrisches immunoessay auf fester oberflaeche, sowie dazu zu verwendender teststab und seine herstellung.
CA1267081C (en) MULTIZONE ANALYTICAL ELEMENT AND BRAND REAGENT
ATE4126T1 (de) Verfahren und reagenz zur enzymatischen bestimmung von enzymsubstraten.
JPS6447953A (en) Method and apparatus for separating labelled reagent for testing immunological bond measuring test
ATE52140T1 (de) Bestimmungsmethode unter einbeziehung einer phasentrennung und testsatz hierfuer.
DK314987D0 (da) Fremgangsmaade til specifik bestemmelse af serumfructosaminindhold samt hertil egnet reagensblanding
ATE77149T1 (de) Verfahren und testkit zur bestimmung freier wirkstoffe in biologischen fluessigkeiten.
ATE161104T1 (de) Verfahren und reagenzien zur ausführung von ioneneinfang-digoxin-assays
ATE160023T1 (de) Verfahren zur bestimmung eines analyts und seine verwendung zur bestimmung von anti-tsh- rezeptorautoantikörpern in einem patientenserum
DE69512909D1 (de) Festphasen-filtrationsverfahren zur antigen- und antikörperprüfung in der blutgruppen-serologie, und testsatz
ATE161332T1 (de) Vorrichtungen zur ausführung von ioneneinfangassays
DE59909404D1 (de) Verfahren zum nachweis von antikörpern oder antigenen sowie zur blutgruppenbestimmung
ATE163764T1 (de) Testverfahren
DE3650691D1 (de) Verfahren zum Messen von Freitestosteronen in biologischen Flüssigkeiten
DE69026497D1 (de) Verfahren zur prüfung von d-vanillylmandelsäure und reagenz und satz dafür
EP0253270A3 (en) Method for diagnostic immunoassay by solid phase separation
KR960706073A (ko) 혈액성분의 검출방법 및 이에 사용하는 킷트
FR2319903A1 (fr) Procede et appareillage pour effectuer des analyses chimiques et cliniques

Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee