ATE91023T1 - Verfahren und vorrichtungen zur durchfuehrung von untersuchungen. - Google Patents
Verfahren und vorrichtungen zur durchfuehrung von untersuchungen.Info
- Publication number
- ATE91023T1 ATE91023T1 AT89900551T AT89900551T ATE91023T1 AT E91023 T1 ATE91023 T1 AT E91023T1 AT 89900551 T AT89900551 T AT 89900551T AT 89900551 T AT89900551 T AT 89900551T AT E91023 T1 ATE91023 T1 AT E91023T1
- Authority
- AT
- Austria
- Prior art keywords
- label
- analyte
- assay
- assay mixture
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000003556 assay Methods 0.000 abstract 6
- 239000012491 analyte Substances 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 230000027455 binding Effects 0.000 abstract 3
- 238000001514 detection method Methods 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 238000000159 protein binding assay Methods 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
- G01N33/5304—Reaction vessels, e.g. agglutination plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/495—Transforming growth factor [TGF]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/795—Porphyrin- or corrin-ring-containing peptides
- G01N2333/805—Haemoglobins; Myoglobins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/969—Multiple layering of reactants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/81—Tube, bottle, or dipstick
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Mycology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12794487A | 1987-12-01 | 1987-12-01 | |
| EP89900551A EP0344276B1 (de) | 1987-12-01 | 1988-11-30 | Verfahren und vorrichtungen zur durchführung von untersuchungen |
| PCT/US1988/004273 WO1989005456A1 (en) | 1987-12-01 | 1988-11-30 | Methods and devices for conducting assays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE91023T1 true ATE91023T1 (de) | 1993-07-15 |
Family
ID=22432784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89900551T ATE91023T1 (de) | 1987-12-01 | 1988-11-30 | Verfahren und vorrichtungen zur durchfuehrung von untersuchungen. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6121055A (de) |
| EP (1) | EP0344276B1 (de) |
| JP (1) | JP2854058B2 (de) |
| AT (1) | ATE91023T1 (de) |
| CA (1) | CA1341076C (de) |
| DE (1) | DE3882040T2 (de) |
| WO (1) | WO1989005456A1 (de) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364591A (en) * | 1992-06-01 | 1994-11-15 | Eastman Kodak Company | Device for moving a target-bearing solid through a liquid for detection while being contained |
| FR2697633B1 (fr) * | 1992-10-21 | 1995-01-20 | Pasteur Sanofi Diagnostics | Procédé d'immunodiagnostic en matrice poreuse avec particules sensibilisées et dispositif pour sa mise en Óoeuvre. |
| US5342790A (en) * | 1992-10-30 | 1994-08-30 | Becton Dickinson And Company | Apparatus for indirect fluorescent assay of blood samples |
| WO1994026414A1 (en) * | 1993-05-17 | 1994-11-24 | Syntex (U.S.A.) Inc. | Reaction container for specific binding assays and method for its use |
| US5905028A (en) * | 1994-05-17 | 1999-05-18 | Gamma Biologicals, Inc. | Method and apparatus useful for detecting bloodgroup antigens and antibodies |
| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| DE19903576C2 (de) * | 1999-01-29 | 2001-02-22 | Bodenseewerk Perkin Elmer Co | Quantitative Bestimmung von Analyten in einem heterogenen System |
| US7361481B2 (en) * | 1999-04-09 | 2008-04-22 | Women's And Children's Hospital | Diagnosis of lysosomal storage disorders using saposins and other markers |
| US6623982B1 (en) | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
| US6613285B1 (en) * | 2000-09-25 | 2003-09-02 | General Electric Company | Reactor plate and method |
| EP1502101B1 (de) | 2001-09-06 | 2012-11-07 | Straus Holdings Inc. | Schneller und empfindlicher nachweis von zellen und viren |
| AU2002361977A1 (en) * | 2001-12-04 | 2003-06-17 | Omx Gmbh | Device and method for processing biological or chemical substances or substance mixtures thereof |
| US20030219469A1 (en) * | 2002-02-11 | 2003-11-27 | Kci Licensing, Inc. | Environmental control device for tissue treatment |
| US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
| SE0203548D0 (sv) * | 2002-12-02 | 2002-12-02 | Biacore Ab | Method of determining site-specificity and kit therefor |
| US8883487B2 (en) * | 2004-12-23 | 2014-11-11 | Abbott Point Of Care Inc. | Molecular diagnostics system and methods |
| US9057046B2 (en) | 2005-09-26 | 2015-06-16 | Rapid Micro Biosystems, Inc. | Cassette containing growth medium |
| US7807354B2 (en) * | 2005-12-28 | 2010-10-05 | Agilent Technologies, Inc. | Low volume hybridization |
| WO2007106013A1 (en) * | 2006-03-13 | 2007-09-20 | Gyros Patent Ab | Enhanced magnetic particle steering |
| US8012744B2 (en) | 2006-10-13 | 2011-09-06 | Theranos, Inc. | Reducing optical interference in a fluidic device |
| US8008034B2 (en) * | 2006-10-13 | 2011-08-30 | Theranos, Inc. | Reducing optical interference in a fluidic device |
| CN102027367B (zh) * | 2008-02-29 | 2016-03-23 | 西北大学 | 促进生物反应的屏障 |
| CN107121396B (zh) * | 2008-09-24 | 2020-06-30 | 曙光生命科学公司 | 用于检测分析物的方法 |
| JP5283113B2 (ja) * | 2008-10-03 | 2013-09-04 | 独立行政法人産業技術総合研究所 | 微量液滴の体積測定方法及び装置 |
| JP6182574B2 (ja) | 2008-10-31 | 2017-08-16 | ビオメリュー・インコーポレイテッド | 分光法を使用した微生物の分離、キャラクタリゼーションおよび/または同定方法 |
| BRPI0919895B1 (pt) * | 2008-10-31 | 2019-08-13 | Bio Merieux Inc | método para identificação de um microorganismo desconhecido a partir de uma amostra de teste |
| US8647835B2 (en) * | 2008-10-31 | 2014-02-11 | BIO MéRIEUX, INC. | Methods for separation, characterization and/or identification of microorganisms using spectroscopy |
| CA2741008C (en) * | 2008-10-31 | 2018-08-28 | Biomerieux, Inc. | Methods for separation and characterization of microorganisms using identifier agents |
| CA2741021C (en) * | 2008-10-31 | 2018-07-17 | Biomerieux, Inc. | Separation device for use in the separation, characterization and/or identification of microorganisms |
| WO2011042828A1 (en) | 2009-10-06 | 2011-04-14 | Koninklijke Philips Electronics N.V. | Magnetic sample purification |
| DE102010041621B4 (de) | 2010-09-29 | 2016-11-03 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | Verfahren zum Transport magnetischer Partikel |
| CN103269787B9 (zh) * | 2010-12-21 | 2016-07-20 | 株式会社岛津制作所 | 用于在管内操作对象成分的器件和方法 |
| KR20140040239A (ko) | 2011-06-19 | 2014-04-02 | 아보젠, 인크. | 샘플 수집을 위한 장치, 용액 및 방법 |
| CN103619727B (zh) * | 2011-06-24 | 2015-04-29 | 株式会社岛津制作所 | 容纳于容器内的物质的分割方法 |
| JP6105613B2 (ja) | 2011-11-07 | 2017-03-29 | ラピッド マイクロ バイオシステムズ インコーポレイテッド | 無菌試験用カセット |
| WO2013145901A1 (ja) * | 2012-03-30 | 2013-10-03 | 株式会社島津製作所 | 分割可能な容器及び容器に収容された物質の分割方法 |
| JP5954532B2 (ja) * | 2012-04-05 | 2016-07-20 | セイコーエプソン株式会社 | 核酸抽出用デバイス、核酸抽出用キット、核酸抽出用装置及び核酸抽出方法 |
| CN107841461A (zh) | 2012-04-16 | 2018-03-27 | 快速微型生物系统公司 | 细胞培养装置 |
| JP2013236559A (ja) * | 2012-05-11 | 2013-11-28 | Sharp Corp | 反応検出方法 |
| JP5483134B2 (ja) * | 2012-10-09 | 2014-05-07 | 独立行政法人産業技術総合研究所 | 微量液滴の体積測定方法及び装置 |
| JP6120518B2 (ja) * | 2012-10-10 | 2017-04-26 | 公益財団法人かずさDna研究所 | 簡易測定器具 |
| JP2014176305A (ja) * | 2013-03-13 | 2014-09-25 | Seiko Epson Corp | 核酸増幅反応用カートリッジ |
| JP2014176304A (ja) * | 2013-03-13 | 2014-09-25 | Seiko Epson Corp | 核酸増幅反応用カートリッジ |
| JP2014176306A (ja) * | 2013-03-13 | 2014-09-25 | Seiko Epson Corp | 核酸増幅反応用カートリッジ |
| EP2969140B1 (de) | 2013-03-15 | 2021-02-17 | Abbott Molecular Inc. | Einstufiges verfahren zur aufreinigung von nukleinsäuren |
| TWI499779B (zh) | 2013-07-04 | 2015-09-11 | Ind Tech Res Inst | 檢測晶片及其使用方法 |
| CN103333680B (zh) * | 2013-07-16 | 2015-05-27 | 北京化工大学 | 一种具有多色荧光特性的二苯基恶唑共晶材料及其制备方法 |
| CN103808923A (zh) * | 2013-11-25 | 2014-05-21 | 珠海迪尔生物工程有限公司 | 一种可移动式磁分离荧光免疫检测分析方法及装置 |
| CN105828947B (zh) | 2013-12-20 | 2017-09-29 | 3M创新有限公司 | 用于样品浓缩和检测的系统和方法 |
| CN111514950A (zh) * | 2013-12-20 | 2020-08-11 | 3M创新有限公司 | 使用分离液进行样品浓缩和检测的系统和方法 |
| CN107980096B (zh) * | 2015-05-19 | 2020-07-24 | 博瑞创新公司 | 低密度不混溶化合物在用于检测样本中分析物的装置中的用途 |
| US10545139B2 (en) * | 2015-06-16 | 2020-01-28 | Curiox Biosystems Pte Ltd. | Methods and devices for performing biological assays using magnetic components |
| US10850280B2 (en) * | 2017-11-17 | 2020-12-01 | Siemens Healthcare Diagnostics Inc. | Method for internally coating a liquid test sample collection device with at least one anticoagulant compound, and devices and kits related thereto |
| CN112740017B (zh) | 2018-04-19 | 2024-12-13 | 曙光诊断学公司 | 靶标检测 |
| JP7091891B2 (ja) * | 2018-07-06 | 2022-06-28 | 株式会社島津製作所 | 磁性体粒子操作用容器 |
| US12480944B2 (en) | 2018-10-04 | 2025-11-25 | First Light Diagnostics, Inc. | Detection and analysis of cells |
| EA202191395A1 (ru) | 2018-11-20 | 2021-08-23 | СПЕКТРУМ СОЛЮШНЗ, ЭлЭлСи | Система сбора образцов, содержащая уплотнительную крышку и клапан |
| CN109735437B (zh) * | 2019-01-28 | 2022-04-19 | 长春长光辰英生物科学仪器有限公司 | 一种细胞弹射分选后用于细胞收集与处理的器皿及方法 |
| US11701094B2 (en) | 2019-06-20 | 2023-07-18 | Spectrum Solutions L.L.C. | Sample collection system including valve and plug assemblies |
| US20220251539A1 (en) * | 2019-10-29 | 2022-08-11 | Hewlett-Packard Development Company, L.P. | Concentrating biological components |
| CN115697561A (zh) * | 2020-04-15 | 2023-02-03 | 伊努梅里斯公司 | 用于产生具有合适澄清度的乳剂的系统和方法及其应用 |
| CN117241878A (zh) | 2021-03-05 | 2023-12-15 | 伊努梅里斯公司 | 用于生成微滴和执行数字分析的系统和方法 |
| EP4351788A4 (de) | 2021-06-04 | 2025-04-09 | Enumerix, Inc. | Zusammensetzungen, verfahren und systeme zur einzelzellenbarcodierung und -sequenzierung |
| US12252745B2 (en) | 2021-09-02 | 2025-03-18 | Enumerix, Inc. | Detection and digital quantitation of multiple targets |
| CN118922556A (zh) | 2021-12-20 | 2024-11-08 | 伊努梅里斯公司 | 多个靶的检测和数字定量 |
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| US4038150A (en) * | 1976-03-24 | 1977-07-26 | J. K. And Susie L. Wadley Research Institute And Blood Bank | Sample mixing and centrifugation apparatus |
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| JPS5510590A (en) * | 1978-05-04 | 1980-01-25 | Wellcome Found | Enzyme immunity quantity analysis |
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| IL56839A0 (en) * | 1979-03-11 | 1979-05-31 | Technion Res & Dev Foundation | Improvement in specific binding assay technique |
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| US4295974A (en) * | 1980-05-05 | 1981-10-20 | Sherwood Medical Industries Inc. | Blood sample collection and phase separation device |
| CA1178257A (en) * | 1980-05-08 | 1984-11-20 | Toshiji Ichikawa | Apparatus for separating blood |
| US4752562A (en) * | 1981-01-23 | 1988-06-21 | Baxter Travenol Laboratories, Inc. | Detection of serum antibody and surface antigen by radial partition immunoassay |
| DE3222962C2 (de) * | 1982-06-19 | 1987-02-19 | Bayer Ag, 5090 Leverkusen | Siliconpasten für die Trennung von Blutproben |
| FI844027A7 (fi) * | 1984-10-12 | 1986-04-13 | Labsystems Oy | Immunologiskt bestaemningsfoerfarande. |
| DE3682502D1 (de) * | 1985-08-21 | 1991-12-19 | Biotope Inc | Verfahren und geraete zur trennung, vermischung und bestimmung von komponenten in spezifischen bindungstests. |
| SE448323B (sv) * | 1985-08-27 | 1987-02-09 | Ersson Nils Olof | Forfarande och anordnig att separera serum eller plasma fran blod |
| FI853523A0 (fi) * | 1985-09-13 | 1985-09-13 | Labsystems Oy | Foerfarande foer utfoering av immunobestaemningar med hjaelp av enzymstaempel. |
| US4868105A (en) * | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
| US4862047A (en) * | 1986-05-21 | 1989-08-29 | Kabushiki Kaisha Komatsu Seisakusho | Apparatus for guiding movement of an unmanned moving body |
| DE3843610A1 (de) * | 1988-01-13 | 1989-07-27 | Stephan Dr Diekmann | Trenn- oder reaktionssaeuleneinheit |
| US5108933A (en) * | 1988-09-16 | 1992-04-28 | Immunicon Corporation | Manipulation of colloids for facilitating magnetic separations |
-
1988
- 1988-11-30 AT AT89900551T patent/ATE91023T1/de not_active IP Right Cessation
- 1988-11-30 DE DE89900551T patent/DE3882040T2/de not_active Expired - Fee Related
- 1988-11-30 EP EP89900551A patent/EP0344276B1/de not_active Expired - Lifetime
- 1988-11-30 JP JP1500610A patent/JP2854058B2/ja not_active Expired - Fee Related
- 1988-11-30 WO PCT/US1988/004273 patent/WO1989005456A1/en not_active Ceased
- 1988-12-01 CA CA000584687A patent/CA1341076C/en not_active Expired - Fee Related
-
1995
- 1995-04-28 US US08/430,265 patent/US6121055A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6121055A (en) | 2000-09-19 |
| EP0344276B1 (de) | 1993-06-23 |
| DE3882040D1 (de) | 1993-07-29 |
| JPH02502405A (ja) | 1990-08-02 |
| WO1989005456A1 (en) | 1989-06-15 |
| CA1341076C (en) | 2000-08-08 |
| EP0344276A1 (de) | 1989-12-06 |
| DE3882040T2 (de) | 1993-09-30 |
| JP2854058B2 (ja) | 1999-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEIH | Change in the person of patent owner | ||
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |