DE3034618C2 - Verfahren zur Bestimmung der Aktivität des Angiotensin-konvertierenden Enzyms - Google Patents

Verfahren zur Bestimmung der Aktivität des Angiotensin-konvertierenden Enzyms

Info

Publication number
DE3034618C2
DE3034618C2 DE3034618A DE3034618A DE3034618C2 DE 3034618 C2 DE3034618 C2 DE 3034618C2 DE 3034618 A DE3034618 A DE 3034618A DE 3034618 A DE3034618 A DE 3034618A DE 3034618 C2 DE3034618 C2 DE 3034618C2
Authority
DE
Germany
Prior art keywords
activity
histidyl
leucine
hippuryl
ace
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3034618A
Other languages
German (de)
English (en)
Other versions
DE3034618A1 (de
Inventor
Yoshihiro Fuchu Tokyo Ashihara
Yasushi Tama Tokyo Kasahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Inc
Original Assignee
Fujizoki Pharmaceutical Co., Ltd., Tokyo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujizoki Pharmaceutical Co., Ltd., Tokyo filed Critical Fujizoki Pharmaceutical Co., Ltd., Tokyo
Publication of DE3034618A1 publication Critical patent/DE3034618A1/de
Application granted granted Critical
Publication of DE3034618C2 publication Critical patent/DE3034618C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
    • C12Q2326/90—Developer
    • C12Q2326/96—4-Amino-antipyrine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE3034618A 1979-09-26 1980-09-13 Verfahren zur Bestimmung der Aktivität des Angiotensin-konvertierenden Enzyms Expired DE3034618C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54122562A JPS5823080B2 (ja) 1979-09-26 1979-09-26 アンジオテンシン変換酵素の活性測定法

Publications (2)

Publication Number Publication Date
DE3034618A1 DE3034618A1 (de) 1981-04-09
DE3034618C2 true DE3034618C2 (de) 1983-01-13

Family

ID=14838956

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3034618A Expired DE3034618C2 (de) 1979-09-26 1980-09-13 Verfahren zur Bestimmung der Aktivität des Angiotensin-konvertierenden Enzyms

Country Status (6)

Country Link
US (1) US4292404A (cg-RX-API-DMAC10.html)
JP (1) JPS5823080B2 (cg-RX-API-DMAC10.html)
DE (1) DE3034618C2 (cg-RX-API-DMAC10.html)
FR (1) FR2465785A1 (cg-RX-API-DMAC10.html)
GB (1) GB2060646B (cg-RX-API-DMAC10.html)
NL (1) NL183832C (cg-RX-API-DMAC10.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3150416A1 (de) * 1980-12-23 1982-08-12 Fujizoki Pharmaceutical Co., Ltd., Tokyo Verfahren und reagenz zur bestimmung der aktivitaet von angiotensin-konvertierendem enzym
DE102022132512A1 (de) 2022-12-07 2024-06-13 Diasys Diagnostic Systems Gmbh Testsystem zur Messung der Enzymaktivität des Angiotensin-konvertierenden Enzyms (ACE)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984004331A1 (fr) * 1983-05-03 1984-11-08 Boehringer Mannheim Gmbh Procede et reactif pour la determination d'"angiotensin converting enzyme"
JPS59227851A (ja) * 1983-06-09 1984-12-21 Sankyo Co Ltd レニン阻害作用を有するペプチド類
US5803357A (en) * 1997-02-19 1998-09-08 Coleman Safety And Security Products, Inc. Thermostat with remote temperature sensors and incorporating a measured temperature feature for averaging ambient temperatures at selected sensors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4108726A (en) * 1976-07-15 1978-08-22 Research Corporation Sarcoidosis test

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3150416A1 (de) * 1980-12-23 1982-08-12 Fujizoki Pharmaceutical Co., Ltd., Tokyo Verfahren und reagenz zur bestimmung der aktivitaet von angiotensin-konvertierendem enzym
DE102022132512A1 (de) 2022-12-07 2024-06-13 Diasys Diagnostic Systems Gmbh Testsystem zur Messung der Enzymaktivität des Angiotensin-konvertierenden Enzyms (ACE)

Also Published As

Publication number Publication date
GB2060646B (en) 1983-06-08
JPS5648899A (en) 1981-05-02
FR2465785B1 (cg-RX-API-DMAC10.html) 1984-08-10
FR2465785A1 (fr) 1981-03-27
GB2060646A (en) 1981-05-07
DE3034618A1 (de) 1981-04-09
JPS5823080B2 (ja) 1983-05-12
NL8005242A (nl) 1981-03-30
US4292404A (en) 1981-09-29
NL183832C (nl) 1989-02-01

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Legal Events

Date Code Title Description
D2 Grant after examination
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: FUJIREBIO K.K., TOKYO, JP

8339 Ceased/non-payment of the annual fee