DE69029107T2 - Substrate für beta-Galactosidase - Google Patents

Substrate für beta-Galactosidase

Info

Publication number
DE69029107T2
DE69029107T2 DE69029107T DE69029107T DE69029107T2 DE 69029107 T2 DE69029107 T2 DE 69029107T2 DE 69029107 T DE69029107 T DE 69029107T DE 69029107 T DE69029107 T DE 69029107T DE 69029107 T2 DE69029107 T2 DE 69029107T2
Authority
DE
Germany
Prior art keywords
galactosidase
beta
substrates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69029107T
Other languages
English (en)
Other versions
DE69029107D1 (de
Inventor
Wayne B Manning
Pyare Khanna
Glenda Choate
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Corp
Original Assignee
Microgenics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microgenics Corp filed Critical Microgenics Corp
Application granted granted Critical
Publication of DE69029107D1 publication Critical patent/DE69029107D1/de
Publication of DE69029107T2 publication Critical patent/DE69029107T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/10—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases p-Nitrophenol derivatives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
DE69029107T 1989-08-16 1990-08-14 Substrate für beta-Galactosidase Expired - Fee Related DE69029107T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/394,495 US5444161A (en) 1989-08-16 1989-08-16 Substrates for β-galactosidase

Publications (2)

Publication Number Publication Date
DE69029107D1 DE69029107D1 (de) 1996-12-19
DE69029107T2 true DE69029107T2 (de) 1997-04-03

Family

ID=23559201

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029107T Expired - Fee Related DE69029107T2 (de) 1989-08-16 1990-08-14 Substrate für beta-Galactosidase

Country Status (7)

Country Link
US (2) US5444161A (de)
EP (1) EP0413561B1 (de)
JP (1) JP2732501B2 (de)
AU (1) AU627611B2 (de)
CA (1) CA1337966C (de)
DE (1) DE69029107T2 (de)
ES (1) ES2095858T3 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4021063A1 (de) * 1990-07-03 1992-01-09 Boehringer Mannheim Gmbh Neue ss-galactosidase-substrate fuer den cedia
ES2039155B1 (es) * 1991-11-15 1994-03-01 Univ Barcelona Autonoma Metodos analiticos y equipos automaticos para la determinacion cuantitativa de beta-galactosidasa.
US5427912A (en) * 1993-08-27 1995-06-27 Boehringer Mannheim Corporation Electrochemical enzymatic complementation immunoassay
JP2935578B2 (ja) * 1994-12-19 1999-08-16 ベーリンガー マンハイム コーポレイション 改善された直線性を有する競合結合アッセイ
AU4893897A (en) * 1997-05-27 1998-12-30 Microgenics Corporation Conjugates and specific immunoassays for the methadone metabolite 2-ethylidine-1,5-dimethyl-3,3-diphenylpyrrolidine
US6512100B1 (en) 1997-10-27 2003-01-28 Ibbex, Inc. Chromogenic substrates of sialidase and methods of making and using the same
US6667161B1 (en) 1997-10-27 2003-12-23 Ibbex, Inc. Chromogenic substrates of sialidase of bacterial, viral, protozoa, and vertebrate origin and methods of making and using the same
EP1124836B1 (de) * 1998-10-27 2005-12-14 IBBEX, Inc. c/o Gryphus Diagnostics, L.L.C. Chromogene sialidasesubstrate und verfahren zu deren herstellung und verwendung
US6262265B1 (en) 1999-06-18 2001-07-17 Microgenics Corporation Non-hydrolyzable analogs of heroin metabolites suitable for use in immunoassay
EP1234873A1 (de) * 2001-02-20 2002-08-28 Deutsches Ressourcenzentrum für Genomforschung GmbH Indikator-Medium für den Nachweis von Verunreinigungen in Gen-Bibliotheken
US7312031B1 (en) 2002-12-06 2007-12-25 The Salk Institute For Biological Studies Alpha-complementation viral fusion assay
US8586294B2 (en) 2004-05-18 2013-11-19 The Board Of Trustees Of The Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
US7138504B2 (en) * 2004-08-12 2006-11-21 Microgenics Corporation Reagents and methods for mycophenolic acid immunoassay
US20060240496A1 (en) * 2005-04-21 2006-10-26 Lakshmi Anne Immunogens, derivatives and immunoassay for ethyl glucuronide
US20070196280A1 (en) * 2006-02-21 2007-08-23 The Government Of The U.S.A. As Represented By The Sec. Of The Dept. Of Health And Human Services In vivo magnetic resonance spectroscopy of aspartate transaminase activity
US8101373B2 (en) * 2007-10-12 2012-01-24 Discoverx Corporation β-galactosidase donor fragments
JP6141327B2 (ja) 2012-02-06 2017-06-07 ディスカヴァーエックス コーポレイション タンパク質存在量の測定による細胞内結合事象の検出
CN106399278B (zh) * 2016-09-22 2019-06-18 北京九强生物技术股份有限公司 一种大肠杆菌β半乳糖苷酶受体及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3427300A (en) * 1965-11-12 1969-02-11 Merck & Co Inc Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
US3427380A (en) * 1966-11-23 1969-02-11 Procter & Gamble Oral compositions for retarding dental plaque formation comprising para-aminobenzoic acid
US3547902A (en) * 1968-12-16 1970-12-15 Bristol Myers Co Coumarin derivatives
JPS59159175A (ja) * 1983-03-02 1984-09-08 Konishiroku Photo Ind Co Ltd 圧力定着性マイクロカプセル型トナ−
DE3345748A1 (de) * 1983-12-17 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim Phenolsulfonphthaleinyl-ss-d-galactoside, verfahren zu deren herstellung sowie deren verwendung zur bestimmung der ss-d-galactosidase
US4708929A (en) * 1984-10-29 1987-11-24 Microgenics Corporation Methods for protein binding enzyme complementation assays
DE3587549T2 (de) * 1984-10-29 1994-02-17 Microgenics Corp Ergänzungstestverfahren von proteine bindenden enzymen.
US4963479A (en) * 1986-10-07 1990-10-16 Hoechst Celanese Corporation Reagent system for an alpha-amylase assay containing aromatic substituted glycoside
IL85581A (en) * 1987-05-21 1992-05-25 Technicon Instr Substrate for beta-galactosidase comprising derivatives of 4-nitrophenyl-beta-d-galactopyranoside and beta-galactosidase immunoassay containing said substrate
US4952495A (en) * 1987-06-08 1990-08-28 Eastman Kodak Company Hydrolyzable compounds which release electron transfer agents and analytical use of same
EP0328106A3 (de) * 1988-02-09 1990-12-19 Konica Corporation Verfahren zur Bestimmung einer Substanz und Immunoassay-Element
EP0411159B1 (de) * 1989-02-23 1995-11-22 Iatron Laboratories, Inc. Verfahren zur bestimmung von enzymatischer wirksamkeit

Also Published As

Publication number Publication date
JPH03175999A (ja) 1991-07-31
DE69029107D1 (de) 1996-12-19
EP0413561A3 (en) 1992-02-26
AU627611B2 (en) 1992-08-27
CA1337966C (en) 1996-01-23
EP0413561A2 (de) 1991-02-20
US5514560A (en) 1996-05-07
US5444161A (en) 1995-08-22
ES2095858T3 (es) 1997-03-01
AU6099290A (en) 1991-02-28
JP2732501B2 (ja) 1998-03-30
EP0413561B1 (de) 1996-11-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ROCHE DIAGNOSTICS CORP., INDIANAPOLIS, IND., US

8339 Ceased/non-payment of the annual fee