FR2465785A1 - Procede pour determiner l'activite de l'enzyme transformant l'angiotensine - Google Patents

Procede pour determiner l'activite de l'enzyme transformant l'angiotensine Download PDF

Info

Publication number
FR2465785A1
FR2465785A1 FR8019999A FR8019999A FR2465785A1 FR 2465785 A1 FR2465785 A1 FR 2465785A1 FR 8019999 A FR8019999 A FR 8019999A FR 8019999 A FR8019999 A FR 8019999A FR 2465785 A1 FR2465785 A1 FR 2465785A1
Authority
FR
France
Prior art keywords
histidyl
leucine
hippuryl
activity
angiotensin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8019999A
Other languages
English (en)
French (fr)
Other versions
FR2465785B1 (cg-RX-API-DMAC10.html
Inventor
Yasushi Kasahara
Yoshihiro Ashihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Inc
Original Assignee
Fujizoki Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujizoki Pharmaceutical Co Ltd filed Critical Fujizoki Pharmaceutical Co Ltd
Publication of FR2465785A1 publication Critical patent/FR2465785A1/fr
Application granted granted Critical
Publication of FR2465785B1 publication Critical patent/FR2465785B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
    • C12Q2326/90—Developer
    • C12Q2326/96—4-Amino-antipyrine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR8019999A 1979-09-26 1980-09-17 Procede pour determiner l'activite de l'enzyme transformant l'angiotensine Granted FR2465785A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54122562A JPS5823080B2 (ja) 1979-09-26 1979-09-26 アンジオテンシン変換酵素の活性測定法

Publications (2)

Publication Number Publication Date
FR2465785A1 true FR2465785A1 (fr) 1981-03-27
FR2465785B1 FR2465785B1 (cg-RX-API-DMAC10.html) 1984-08-10

Family

ID=14838956

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8019999A Granted FR2465785A1 (fr) 1979-09-26 1980-09-17 Procede pour determiner l'activite de l'enzyme transformant l'angiotensine

Country Status (6)

Country Link
US (1) US4292404A (cg-RX-API-DMAC10.html)
JP (1) JPS5823080B2 (cg-RX-API-DMAC10.html)
DE (1) DE3034618C2 (cg-RX-API-DMAC10.html)
FR (1) FR2465785A1 (cg-RX-API-DMAC10.html)
GB (1) GB2060646B (cg-RX-API-DMAC10.html)
NL (1) NL183832C (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2496694A1 (fr) * 1980-12-23 1982-06-25 Fujizoki Seiyaku Kk Procede de determination de l'activite de l'enzyme transformant l'angiotensine

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984004331A1 (fr) * 1983-05-03 1984-11-08 Boehringer Mannheim Gmbh Procede et reactif pour la determination d'"angiotensin converting enzyme"
JPS59227851A (ja) * 1983-06-09 1984-12-21 Sankyo Co Ltd レニン阻害作用を有するペプチド類
US5803357A (en) * 1997-02-19 1998-09-08 Coleman Safety And Security Products, Inc. Thermostat with remote temperature sensors and incorporating a measured temperature feature for averaging ambient temperatures at selected sensors
DE102022132512A1 (de) * 2022-12-07 2024-06-13 Diasys Diagnostic Systems Gmbh Testsystem zur Messung der Enzymaktivität des Angiotensin-konvertierenden Enzyms (ACE)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4108726A (en) * 1976-07-15 1978-08-22 Research Corporation Sarcoidosis test

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2496694A1 (fr) * 1980-12-23 1982-06-25 Fujizoki Seiyaku Kk Procede de determination de l'activite de l'enzyme transformant l'angiotensine

Also Published As

Publication number Publication date
GB2060646B (en) 1983-06-08
JPS5648899A (en) 1981-05-02
FR2465785B1 (cg-RX-API-DMAC10.html) 1984-08-10
GB2060646A (en) 1981-05-07
DE3034618A1 (de) 1981-04-09
JPS5823080B2 (ja) 1983-05-12
NL8005242A (nl) 1981-03-30
US4292404A (en) 1981-09-29
DE3034618C2 (de) 1983-01-13
NL183832C (nl) 1989-02-01

Similar Documents

Publication Publication Date Title
Goodman et al. Peptide synthesis via active esters. IV. Racemization and ring-opening reactions of opitcally active oxazolones
JP2003513025A (ja) ８−（アリニノ）−１−ナフタレンスルホネート類似物およびそれらを分析物検出検定で用いる使用
US4167449A (en) Composition and method for determining transferase and protease activity
CN109438319B (zh) 一种检测亮氨酸氨肽酶的化合物及其制备方法和应用
CH627734A5 (fr) Procede de synthese de peptides modifies.
EP0447324A1 (fr) Dérivés de pyrimidinedione-2,4 et médicaments les contenant
JPS5856695A (ja) 新規なトロンビン測定用基質
FR2459226A1 (fr) Nouveaux amides de tripeptides, utiles dans la determination quantitative d'enzymes proteolytiques
FR2465785A1 (fr) Procede pour determiner l'activite de l'enzyme transformant l'angiotensine
EP0056210B1 (fr) Procédé pour le dosage fluorimétrique des endotoxines, nouveaux peptides portant un fluorophore utilisables dans ledit procédé et leur méthode de préparation
EP0309324A1 (fr) Procédé de synthèse d'alpha amino N alkyles et de leurs esters. Application à la synthèse de carboxyalkyl dipeptides
EP0516532B1 (fr) Dérivés de coumarines hydrosolubles, leur préparation et leur utilisation comme substrat d'enzyme ou pour la préparation de tels substrats
FR2669638A1 (fr) Procede de preparation de dipeptides.
FR2490222A1 (fr) Derives de la phenylalanylarginine, procede pour leur preparation et procede de mesure de l'activite d'enzymes utilisant ceux-ci
JPS5863399A (ja) 新規なプラスミン測定用基質
CN111675728B (zh) 基于苯硒醚基团专一响应Cys的荧光探针、制备方法及应用
EP0162877B1 (fr) Méthode de dosage d'enzymes
CH645992A5 (en) Reagent for the fluorimetric determination of transferase and protease activity and its use for this determination
FR2479817A1 (fr) Nouveau substrat synthetique contenant un amide et procede de determination de l'activite enzymatique de la leucine aminopeptidase
FR2584399A1 (fr) Procede de synthese stereospecifique d'acides amino-4 hydroxy-3 carboxyliques
FR2609985A1 (fr) Procede de n-o trifluoroacetylation des a, o diaminoacides monocarboxyliques aliphatiques satures
EP0363263B1 (fr) Procédé de préparation de dérives de l'acide propionique
RU2841339C1 (ru) 2-(4-Карбонилбензилидено)диптерокарпол, проявляющий гипогликемическую активность, его применение и способ его получения
CA1257186A (fr) Methode de dosage utilisant au moins un derive peptidique
BE899539A (fr) Procede permettant de determiner la cathepsine b en presence d'autres enzymes proteolytiques et composes utiles a cet effet.

Legal Events

Date Code Title Description
CD Change of name or company name
ST Notification of lapse